For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2452 | - | - | 100% (493) | putative sensor histidine kinase PhoR |
| M. thermoresistible (build 8) | TH_4550 | - | 3e-31 | 31.66% (338) | PUTATIVE putative integral membrane sensor signal transduction |
| M. thermoresistible (build 8) | TH_2428 | - | 2e-25 | 30.79% (302) | PUTATIVE integral membrane sensor signal transduction histidine |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0781 | phoR | 4e-38 | 28.93% (484) | two component system response sensor kinase membrane |
| M. gilvum PYR-GCK | Mflv_1582 | - | 6e-38 | 30.50% (518) | integral membrane sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv0758 | phoR | 6e-39 | 29.13% (484) | two component system response sensor kinase membrane |
| M. leprae Br4923 | MLBr_00175 | - | 6e-25 | 30.70% (316) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_0674 | - | 3e-38 | 35.74% (319) | putative sensor histidine kinase PhoR |
| M. marinum M | MMAR_4941 | phoR | 4e-38 | 32.85% (414) | two-component system response phosphate sensor kinase, PhoR |
| M. avium 104 | MAV_0703 | - | 6e-38 | 30.97% (507) | sensor histidine kinase PhoR |
| M. smegmatis MC2 155 | MSMEG_5870 | - | 7e-39 | 35.90% (312) | sensor histidine kinase PhoR |
| M. ulcerans Agy99 | MUL_0464 | phoR | 3e-38 | 32.85% (414) | two component system response phosphate sensor kinase, PhoR |
| M. vanbaalenii PYR-1 | Mvan_5174 | - | 7e-38 | 30.18% (507) | integral membrane sensor signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4941|M.marinum_M ------MAER-------------------LPRAVP--LRVGLVAATLALV
MUL_0464|M.ulcerans_Agy99 ------MAER-------------------LPRAVQ--LRVGLVAATLALV
MAV_0703|M.avium_104 -----MVVTR-------------------PRRGLP--LRVGLVAATLALV
Mb0781|M.bovis_AF2122/97 ------MARH-------------------LRGRLP--LRVRLVAATLILV
Rv0758|M.tuberculosis_H37Rv ------MARH-------------------LRGRLP--LRVRLVAATLILV
Mflv_1582|M.gilvum_PYR-GCK ------MSSASPDERSNLNNGDVAGRRRYLRRGVP--LRVALVAATLLLV
Mvan_5174|M.vanbaalenii_PYR-1 ------MDGG---DGPTLNNGGVPGR---IRRGVP--LRVGLVAAMLLLV
MSMEG_5870|M.smegmatis_MC2_155 ------MNRG--------------------RRGIP--LRVGLVAAALVLV
MAB_0674|M.abscessus_ATCC_1997 MAWDTYCASRDERLREEQLALLVAVPG--VRRGVP--LRVSLVVGTLVLV
TH_2452|M.thermoresistible__bu MTSE----------------PPSPSGRPRWRRLLPSAARTRIIGWVLLLV
MLBr_00175|M.leprae_Br4923 MVRFAWRRRAS------------------LRATSSLSLRWRVMLLAMSMV
* :: : :*
MMAR_4941|M.marinum_M LCGLLASGVAVTSILRHSLVSRIDSTLLEASRTWAQASWRHSMPSVEGPD
MUL_0464|M.ulcerans_Agy99 LCGLLASGVAVTSILRHSLVSRIDSTLLEASRTWAQASWRHSMPSVEGPD
MAV_0703|M.avium_104 ACGLAVSGIAVTSILRHSLVSRIDSTLLDASRGWAQAPRRQSSSAYEGPD
Mb0781|M.bovis_AF2122/97 ATGLVASGIAVTSMLQHRLTSRIDRVLLEEAQIWAQITLPLAPDPYPIHN
Rv0758|M.tuberculosis_H37Rv ATGLVASGIAVTSMLQHRLTSRIDRVLLEEAQIWAQITLPLAPDPYPGHN
Mflv_1582|M.gilvum_PYR-GCK ACGLLASGIAVTTIMQHSLMNRVDDTLLDASRGWAQVPRRLPTITVDDPN
Mvan_5174|M.vanbaalenii_PYR-1 ACGLLASGIAVTTIMQHSLMNRVDDTLLDASRGWAQVPRRVLTVPMEGPN
MSMEG_5870|M.smegmatis_MC2_155 ACGLLASGIAVTSIMRHTEVSRIDQTLLDASRSWAQAPRRAPTTPLEGPN
MAB_0674|M.abscessus_ATCC_1997 ALGLVASGIAVTTTMQRTMMNRADRELIDAANGWANRP--PPPPPAFETT
TH_2452|M.thermoresistible__bu MVALGVVTLTTWRLMVSSIDARMDEALHIEVDEFEELTASGLNPRTGAPF
MLBr_00175|M.leprae_Br4923 AMVVVLMAFAVYVVISAALYSDIDNQLQSRAQLLIASGSLAADPGKAIEG
: .:. : * *
MMAR_4941|M.marinum_M P--------------ARP--------PSKFYVRSISPDGRAMTAINDRN-
MUL_0464|M.ulcerans_Agy99 P--------------ARP--------PSKFYVRSISPDGRAMTAINDRN-
MAV_0703|M.avium_104 P--------------GRP--------PSKFYVRGVSTDGTPFTAINDRN-
Mb0781|M.bovis_AF2122/97 P--------------DRP--------PSRFYVRVISPDGQSYTALNDNT-
Rv0758|M.tuberculosis_H37Rv P--------------DRP--------PSRFYVRVISPDGQSYTALNDNT-
Mflv_1582|M.gilvum_PYR-GCK P--------------ARP--------PSDFYVRGIDPDGHVWMLINDRE-
Mvan_5174|M.vanbaalenii_PYR-1 P--------------ARP--------PSDFYVRAVDPDGHVWMEVNDRE-
MSMEG_5870|M.smegmatis_MC2_155 P--------------ARP--------PSNFYVRGFDEDGRTWIAVNDRE-
MAB_0674|M.abscessus_ATCC_1997 R--------------HRP--------PSLFFIRTTDDRGRVVIMLNDRAR
TH_2452|M.thermoresistible__bu TGVAEVIREAIAYNLARPNEKFLGYVDGEYHTQSRQEPGFPEVLAGDDAF
MLBr_00175|M.leprae_Br4923 T-------------------------AYSDVNAMLVNPGHSIYTANQPGQ
* .:
MMAR_4941|M.marinum_M AEPALPADNDVGSDPTTLPSVNGSNIEWRAVSVHGPQGGLTTVAIDLSDV
MUL_0464|M.ulcerans_Agy99 AEPALPADNDVGSDPTTLPSVNGSNIEWRAVSVHGPQGGLTTVAIDLSDV
MAV_0703|M.avium_104 AEPALPADNDVGPNPTTLPSVNGSDIQWRAVSVRGPHG-LTTVAIDLSDV
Mb0781|M.bovis_AF2122/97 AIPAVPANNDVGRHPTTLPSIGGSKTLWRAVSVRASDGYLTTVAIDLADV
Rv0758|M.tuberculosis_H37Rv AIPAVPANNDVGRHPTTLPSIGGSKTLWRAVSVRASDGYLTTVAIDLADV
Mflv_1582|M.gilvum_PYR-GCK AEPELPADNNVGPEPRTVGSVDHSDVQWRAMTVRGLRGELTTVAIDLSDV
Mvan_5174|M.vanbaalenii_PYR-1 AEPALPEDNDVGSEPVTVASVDHSHVQWRAMTVRGLSGELTTVAIDLSDV
MSMEG_5870|M.smegmatis_MC2_155 AEPALPENNDVGPVPVTVGSIDKSNVEWRAMTVRGPNGELTTVAIDLSEV
MAB_0674|M.abscessus_ATCC_1997 ADPDLPFDNDVGGRPVTVRSSDGG-TEWRAVSRHDALGGYTTVARDITDV
TH_2452|M.thermoresistible__bu TERVATVTEPVEG-SYDHPEVGEVRYLAIPVTMAGDPAQGVIVAAYLGDA
MLBr_00175|M.leprae_Br4923 TLPVGTAEKAVIRGELFMSQRTASDQRILAIHLPNDSSLLISKSLRPTEA
: . : * . .: . : :.
MMAR_4941|M.marinum_M Q-HTVRSLVWLQIGIGAGVLVVVGLAGFAVVQRSLRPLSEVEQTAAAIAS
MUL_0464|M.ulcerans_Agy99 Q-HTVRSLVWLQIGIGAGVLVVVGLAGFAVVQRSLRPLSEVEQTAAAIAS
MAV_0703|M.avium_104 Q-HTVSSLVWLQIGIGVAVLAVVGIASFAVVQRSLRPLVEVEQTAAAIAA
Mb0781|M.bovis_AF2122/97 R-STVRSLVLLQVGIGSAVLVVLGVAGYAVVRRSLRPLAEFEQTAAAIGA
Rv0758|M.tuberculosis_H37Rv R-STVRSLVLLQVGIGSAVLVVPGVAGYAVVRRSLRPLAEFEQTAAAIGA
Mflv_1582|M.gilvum_PYR-GCK K-STMRSLVYTQVGIGAAVLLVLGIAGYAVVHRSLRPLSEVEQTAAAIAA
Mvan_5174|M.vanbaalenii_PYR-1 K-STVRSLVYTQAGFGVAVLVVLGIAGYAVVHRSLRPLSEVEQTAAAIAA
MSMEG_5870|M.smegmatis_MC2_155 Q-SSVRALVWSQVGIGAAVLLVLGVVGYVVVHRSLRPLVEVERTAAAIAA
MAB_0674|M.abscessus_ATCC_1997 R-TTVRDLLWLQVAIGIAVLTVLGVAGYWLVHRSLRPLAEVEATAADIAA
TH_2452|M.thermoresistible__bu ERAAADDAARLMLLVGAATLFGAIGAAWLVAGRILRPLRDVADTARTITD
MLBr_00175|M.leprae_Br4923 V---MTKLRWVLLIVGSLGVAVAAVAGGMVTRAGLRPVGRLTEAAERVAR
.* : .. :. ***: . :* :
MMAR_4941|M.marinum_M GQLDRRVPERDPRTEVGQLSLAMNGMLSQIQVALAASEDSAEKARSSEER
MUL_0464|M.ulcerans_Agy99 GQLDRRVPERDPRTEVGQLSLAMNGMLSQIQVALAASEDSAEKARSSEER
MAV_0703|M.avium_104 GQLDRRVPERDPRTEVGRLSLALNGMLAQIQQALASSESSAEKARGSEDR
Mb0781|M.bovis_AF2122/97 GQLDRRVPQWHPRTEVGRLSLALNGMLAQIQRAVASAESSAEKARDSEDR
Rv0758|M.tuberculosis_H37Rv GQLDRRVPQWHPRTEVGRLSLALNGMLAQIQRAVASAESSAEKARDSEDR
Mflv_1582|M.gilvum_PYR-GCK GQLDRRVPERDPRTEVGRLSLALNGMLAQIQHAMALSESSAEKARSSEDR
Mvan_5174|M.vanbaalenii_PYR-1 GQLDRRVPERDPRTEVGRLSLALNGMLAQIQRAMASSEASAEQARTSEDR
MSMEG_5870|M.smegmatis_MC2_155 GQLDRRVPERDPRTEVGRLSSALNGMLAQIQRAVAASEASAEQARSSEDR
MAB_0674|M.abscessus_ATCC_1997 GHLDRRVPERDPRTEVGRLSLALNGMLAQIQRAVADSEKSAKAARTSEER
TH_2452|M.thermoresistible__bu TDLSRRIPSRGEGDEMDSLVRTINGMLDRIEAGVS--------------A
MLBr_00175|M.leprae_Br4923 TDDLRPIPVFGS-DELARLTEAFNLMLRALAESRE--------------R
. * :* *: * ::* ** : .
MMAR_4941|M.marinum_M MRRFITDASHELRTPLTTIRGFAELYRQGAA--------RDVAMLLSRIE
MUL_0464|M.ulcerans_Agy99 MRRFITDASHELRTPLTTIRGFAELYRQGAA--------RDVAMLLSRIE
MAV_0703|M.avium_104 MRRFITDASHELRTPLTTIRGFAELYRQGAA--------RDVAMLLSRIE
Mb0781|M.bovis_AF2122/97 MRQFITDASHELRTPLTTIRGFAELYRQGAA--------RDVGMLLSRIE
Rv0758|M.tuberculosis_H37Rv MRQFITDASHELRTPLTTIRGFAELYRQGAA--------RDVGMLLSRIE
Mflv_1582|M.gilvum_PYR-GCK MRRFITDASHELRTPLTTIRGFAELYRQGAA--------RDVEMLMGRIK
Mvan_5174|M.vanbaalenii_PYR-1 MRRFITDASHELRTPLTTIRGFAELYRQGAA--------RDVEMLMSRIE
MSMEG_5870|M.smegmatis_MC2_155 MRRFITDASHELRTPLTTIRGFAELYRQGAA--------RDIEMLMGRIE
MAB_0674|M.abscessus_ATCC_1997 MRRFITDASHELRTPLTTIRGYAELYRQGAA--------TDTELVLGRIE
TH_2452|M.thermoresistible__bu QRRFIDDAGHELRTPITIVRGHLEVLDPDDP--------DDVRSTVALVD
MLBr_00175|M.leprae_Br4923 QARLVTDAGHELRTPLTSLRTNVELLIASMAPEAPRLPDQEMADLRADVL
::: **.******:* :* *: . . : . :
MMAR_4941|M.marinum_M SEASRMGLLVDDLLTLARLDVQRPLERNRVDLLVLAADAVHDARAIDRKR
MUL_0464|M.ulcerans_Agy99 SEASRMGLLVDDLLTLARLDVQRPLERNRVDLLVLAADAVHDARAIDRKR
MAV_0703|M.avium_104 SEASRMGLLVDDLLLLARLDVQRPLEHHRVDLLALASDAVHDAQAMDPKR
Mb0781|M.bovis_AF2122/97 SEASRMGLLVDDLLLLARLDAHRPLELCRVDLLALASDAAHDARAMDPKR
Rv0758|M.tuberculosis_H37Rv SEASRMGLLVDDLLLLARLDAHRPLELCRVDLLALASDAAHDARAMDPKR
Mflv_1582|M.gilvum_PYR-GCK SESRRMGLLVEDLLLLARLDAQRPLEHRRVDLLALASDTVHDAQSIAPKR
Mvan_5174|M.vanbaalenii_PYR-1 SESRRMGLLVEDLLLLARLDAQRPLDRHRVDLLTLATDAVHDAQSIAPKR
MSMEG_5870|M.smegmatis_MC2_155 SESRRMGLLVEDLLLLARLDAQRPLERRRVDLLALATDAVHDAQSIAPKR
MAB_0674|M.abscessus_ATCC_1997 GESTRMGQLVEDLLLLARLDAHRPMEQRLVDLLVLATDAVHDAKATAPER
TH_2452|M.thermoresistible__bu DELVRMNRMVTDLLLLARSEQPTFLTPEPTDIGALTRAIFDKVVQLGDRD
MLBr_00175|M.leprae_Br4923 AQIEELSTLVGDLVDLTRDDAG-QVVHEPIDMSEVLYRSLERVRRRRNDI
: .:. :* **: *:* : : *: : . .
MMAR_4941|M.marinum_M AITVEVLEGPGTPEVLGDEPRLRQVLSNLVGNALQHTPDSADVTVRVGTA
MUL_0464|M.ulcerans_Agy99 AITVEVLEGPGTPEVLGDEPRLRQVLSNLVGNALQHTPDSADVTVRVGTA
MAV_0703|M.avium_104 TITLEVLDGPGTPEVFGDEPRIRQVLGNLIANALQHTPESADVTVRVGTD
Mb0781|M.bovis_AF2122/97 RITLEVLDGPGTPEVLGDESRLRQVLRNLVANAIQHTPESADVTVRVGTE
Rv0758|M.tuberculosis_H37Rv RITLEVLDGPGTPEVLGDESRLRQVLRNLVANAIQHTPESADVTVRVGTE
Mflv_1582|M.gilvum_PYR-GCK RIRMEVFDGPGTPEVLGDEARLRQVLSNLVANALQHTPESAGVTVRVGTA
Mvan_5174|M.vanbaalenii_PYR-1 SIKMEVFDGPGTPEVLGDEPRLRQVLSNLVANALQHTPETAAVTVRVGTD
MSMEG_5870|M.smegmatis_MC2_155 RVKMEVFDGPGTPEVLGDEARLRQVIGNLVANAVQHTPETAGITVRVGTD
MAB_0674|M.abscessus_ATCC_1997 DVELEVFDGPGTPEVIGDELRLRQVLGNLVSNALGHT--TAAVRVRVGTE
TH_2452|M.thermoresistible__bu ----YQLQSVAEVTAVLDAQRITQALIALADNACRYTRDGDWIAVGSGLY
MLBr_00175|M.leprae_Br4923 HFDVQAIG----WQIYGDAAGLSRAVLNLMDNAAKWSPSGGRVVVTMRQF
: * : :.: * ** : : *
MMAR_4941|M.marinum_M G-QNAVLEVADKGPGMPAEDAARVFERFYRTDSSRARASGGTGLGLSIVH
MUL_0464|M.ulcerans_Agy99 G-ENAVLEVADKGPGMPAEDAARVFERFYRTDSSRARASGGTGLGLSIVH
MAV_0703|M.avium_104 G-DDAVLEVADRGPGMNEQDASRVFERFYRTDSSRARASGGTGLGLSIVE
Mb0781|M.bovis_AF2122/97 G-DDAILEVADDGPGMSQEDALRVFERFYRADSSRARASGGTGLGLSIVD
Rv0758|M.tuberculosis_H37Rv G-DDAILEVADDGPGMSQEDALRVFERFYRADSSRARASGGTGLGLSIVD
Mflv_1582|M.gilvum_PYR-GCK D-DTAIVEVCDEGPGMTGEDAQRVFERFYRADSSRARASGGTGLGLSIVD
Mvan_5174|M.vanbaalenii_PYR-1 G-NDAVVEVCDEGPGMRPEDAQRVFERFYRTDTSRARASGGTGLGLSIVD
MSMEG_5870|M.smegmatis_MC2_155 G-DNAVLEVCDEGPGMSQEDARRVFERFYRADTSRTRASGGTGLGLSIVD
MAB_0674|M.abscessus_ATCC_1997 G-DDAVLEVIDRGPGMTKTDAERVFERFYRADSSRTRSSGGTGLGLSIVD
TH_2452|M.thermoresistible__bu D-GWLRFWVSDSGPGVSDADRDRIFERFARGSAGGQR-SDGAGLGLSIVR
MLBr_00175|M.leprae_Br4923 DPSHVELVVSDYGPGIPPQERRLVFERFYRSTT--ARSLPGSGLGLAIVK
. . * * ***: : :**** * : * *:****:**
MMAR_4941|M.marinum_M SLVKAHGGDVTLTTAPG----EGCCFRVTLP----RVSEAAVEL------
MUL_0464|M.ulcerans_Agy99 SLVKAHGGDVTLTTAPG----EGCCFRVTLP----RVSEAAVEL------
MAV_0703|M.avium_104 SLVRAHGGTVGVTTAPG----QGCCFRVTLP----RISDVPAVQ------
Mb0781|M.bovis_AF2122/97 SLVAAHGGAVTVTTALG----EGCCFRVSLP----RVSDVDQLS------
Rv0758|M.tuberculosis_H37Rv SLVAAHGGAVTVTTALG----EGCCFRVSLP----RVSDVDQLS------
Mflv_1582|M.gilvum_PYR-GCK SLVYAHGGRVSVTTAPG----CGCRFTVRLP----RVTDERLREEQATDE
Mvan_5174|M.vanbaalenii_PYR-1 SLVYAHGGRVSVTTAPG----QGSRFRVSLP----RIADAGP--------
MSMEG_5870|M.smegmatis_MC2_155 SLVYAHGGTVKVTTALG----KGSRFTVSLP----RIADLPARL------
MAB_0674|M.abscessus_ATCC_1997 ALTAAHGGTVTVHTAPG----AGCRFEVRLP----RADMTDDDADVDEPE
TH_2452|M.thermoresistible__bu AIAGAHGGHVDLDTVVG----RGSTFTITIP----AVLEAPWPAS-----
MLBr_00175|M.leprae_Br4923 QVVINHGGLLRVEDTAPGVQPPGTSIYVLLPGRPMPVSAYSTLADQDMGE
:. *** : : . * : : :*
MMAR_4941|M.marinum_M ----------------------TEPVS----------
MUL_0464|M.ulcerans_Agy99 ----------------------TEPVS----------
MAV_0703|M.avium_104 ----------------------AS-------------
Mb0781|M.bovis_AF2122/97 ----------------------LTPVVPGPP------
Rv0758|M.tuberculosis_H37Rv ----------------------LTPVVPGPP------
Mflv_1582|M.gilvum_PYR-GCK RLREEQMPAPEHAGEESRGEQTDVPVSATAPTPP---
Mvan_5174|M.vanbaalenii_PYR-1 ----------------DAGPDAEVPVSSAQLG-----
MSMEG_5870|M.smegmatis_MC2_155 -------------------------------------
MAB_0674|M.abscessus_ATCC_1997 ----------SATPDAAASEPKIVRASRSESAQP---
TH_2452|M.thermoresistible__bu -------------------------------------
MLBr_00175|M.leprae_Br4923 ANFQDKIGPAVQVSGKSANFRDSAHVISVDYQSARAR