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TETAPGALTERRGNVLLITINRPEARNAINSSVSQAVGDALAEAQNDPEVRAVVLTGAGDKSFCAGADLK AISRGENLFHPEHPEYGFAGYVSHFIDKPTIAAVNGTALGGGTELALASDLVVAEERAMFGLPEVKRGLI AGAGGVFRIIEQLPRKVALELVYTGDPISAADALKWGLINQVVPDGTVVDAALALAERITCNAPLAVQAS KRVAYGAEEGTVPAEQPSWKRTNREFVTLLKTEDAMEGPLAFAQKRQPVWKAK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5198 | - | - | 100% (264) | carnitinyl-CoA dehydratase |
| M. smegmatis MC2 155 | MSMEG_2227 | - | 2e-54 | 45.85% (253) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5915 | - | 2e-46 | 39.70% (267) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 4e-46 | 40.60% (266) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2117 | - | 1e-129 | 87.69% (260) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 2e-58 | 47.13% (261) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-32 | 36.36% (242) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4588c | - | 2e-57 | 47.31% (260) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4317 | echA1_1 | 1e-112 | 75.29% (259) | enoyl-CoA hydratase, EchA1_1 |
| M. avium 104 | MAV_2597 | - | 1e-121 | 80.84% (261) | carnitinyl-CoA dehydratase |
| M. thermoresistible (build 8) | TH_4237 | - | 1e-102 | 84.36% (211) | PUTATIVE carnitinyl-CoA dehydratase |
| M. ulcerans Agy99 | MUL_0972 | echA1_1 | 1e-108 | 72.59% (259) | enoyl-CoA hydratase, EchA1_1 |
| M. vanbaalenii PYR-1 | Mvan_4588 | - | 1e-131 | 87.12% (264) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2117|M.gilvum_PYR-GCK --------MA-PGALTERRGNVLIITINRPEARNAINASVSIAVGDALQA
Mvan_4588|M.vanbaalenii_PYR-1 -MTDTVTDTA-PGALTERRGNVLIITINRPEARNAVNASVSIGVGNALQA
MSMEG_5198|M.smegmatis_MC2_155 -----MTETA-PGALTERRGNVLLITINRPEARNAINSSVSQAVGDALAE
TH_4237|M.thermoresistible__bu --------------------------------------------------
MAV_2597|M.avium_104 -MAETLTEVTRQAAVVERRGNVALITIDRPDARNAVNGAVSTAVGDALEE
MMAR_4317|M.marinum_M ---MTDAGDDQPAGLVEHRGNVMVITINRPEARNAINGAVSVAVGDALES
MUL_0972|M.ulcerans_Agy99 ---MTDAGDDQPAGLVEHRGNVMVITINRPEARNAINGAVSVAVGGALES
Rv0222|M.tuberculosis_H37Rv MSSESDAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQ
MAB_4588c|M.abscessus_ATCC_199 ---------MADEVLIEQRDRVLLITINRPDARNAVNRAVSQGLAAAADQ
Mb3545|M.bovis_AF2122/97 -------MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDR
MLBr_02402|M.leprae_Br4923 --------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKE
Mflv_2117|M.gilvum_PYR-GCK AQEDPDVRAVILTGAGDKSFCAGADLKAISR---GENLFHPEHSEWGFAG
Mvan_4588|M.vanbaalenii_PYR-1 AQDDPEIRAVILTGAGDKSFCAGADLKAISR---GENLFHPEHTEWGFAG
MSMEG_5198|M.smegmatis_MC2_155 AQNDPEVRAVVLTGAGDKSFCAGADLKAISR---GENLFHPEHPEYGFAG
TH_4237|M.thermoresistible__bu ---------VVLTGSGDKSFCAGADLKAIAR---GENLFHPDHPEWGFAG
MAV_2597|M.avium_104 AQRDPEVWAVVITGAGDKSFCAGADLKAISR---GENLYHAEHPEWGFAG
MMAR_4317|M.marinum_M AQNDPEVRAVVITGAGDKSFCAGADLLAISR---RENIYHPDHNEWGFAG
MUL_0972|M.ulcerans_Agy99 AQNDAEVRAVVITGAGDKSFCAGADLLAISR---RENIYHPDHNEWGFAG
Rv0222|M.tuberculosis_H37Rv LDGDAGLSVAILTGGGG-SFCAGMDLKAFAR---GENVVVEG----RGLG
MAB_4588c|M.abscessus_ATCC_199 LDSSADLSVAIITGAGG-NFCAGMDLKAFVS---GEAVLSE-----RGLG
Mb3545|M.bovis_AF2122/97 VDNDPDIRCCILTGAGG-YFCAGMDLKAATQKPPGDSFKDGSYDPSRIDA
MLBr_02402|M.leprae_Br4923 LDIDPDVGAILITGSPK-VFAAGADIKEMAS-----LTFTDAFDADFFSA
::**. *.** *: .
Mflv_2117|M.gilvum_PYR-GCK YVR-HFIDKPTIAAVNGTALGGGTELALASDLVVAEERAKFGLPEVKRGL
Mvan_4588|M.vanbaalenii_PYR-1 YVR-HFIDKPTIAAVNGTALGGGTELALASDLVVAEERAKFGLPEVKRGL
MSMEG_5198|M.smegmatis_MC2_155 YVS-HFIDKPTIAAVNGTALGGGTELALASDLVVAEERAMFGLPEVKRGL
TH_4237|M.thermoresistible__bu YVR-HFMDKPTIAAVNGTALGGGTELALASDLVVARESAVFGLPEVKRGL
MAV_2597|M.avium_104 YVH-HFIDKPTIAAVNGTALGGGSELALASDLVIACESASFGLPEVKRGL
MMAR_4317|M.marinum_M YVH-HFIDKPTIAAVNGTALGGGTELALASDLVVADERAKFGLPEVKRGL
MUL_0972|M.ulcerans_Agy99 YVH-HFIDKPTIAAVNGTALCGGTELALASDLVVADERAKFGLPEAKRGF
Rv0222|M.tuberculosis_H37Rv FTE-RPPTKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRGL
MAB_4588c|M.abscessus_ATCC_199 FTN-VPPRKPIIAAVEGFALAGGTELVLSCDLVVAGRSAKFGIPEVKRGL
Mb3545|M.bovis_AF2122/97 LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSL
MLBr_02402|M.leprae_Br4923 WGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
.* **** * *: ** *: *: :* : ** .* * ..
Mflv_2117|M.gilvum_PYR-GCK IAGAGGVFRIVEQLPRKVALELIYTGEPISSADALRWGLINQVVPDGTVV
Mvan_4588|M.vanbaalenii_PYR-1 IAGAGGVFRIVEQLPRKVALELIYTGEPISSADALRWGLINQVVPDGTVV
MSMEG_5198|M.smegmatis_MC2_155 IAGAGGVFRIIEQLPRKVALELVYTGDPISAADALKWGLINQVVPDGTVV
TH_4237|M.thermoresistible__bu IAGAGGVFRIVEQLPRKVALELLFTGEPITAAEALRWGLINEVVPDGAEL
MAV_2597|M.avium_104 IAGAGGVFRIVEQLPRKVALELVLTGEPMTASDALRWGLINEVVPDGTVV
MMAR_4317|M.marinum_M IAAAGGVFRIVNQLPRKVAMEMLLTGEPITASDAYEWGLINQVVKQGAVL
MUL_0972|M.ulcerans_Agy99 IAAAGGVFRIVNQLPRKVAMEMLLTGEPITASDAYEWGLINQVVKQGAVL
Rv0222|M.tuberculosis_H37Rv VAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTAL
MAB_4588c|M.abscessus_ATCC_199 VAGAGGLLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQAL
Mb3545|M.bovis_AF2122/97 YPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQAL
MLBr_02402|M.leprae_Br4923 LPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLL
. *. *: . : * :: ** : : * . *::. :. . :
Mflv_2117|M.gilvum_PYR-GCK DAALALAERITCNAPLAVRASKRVSYGAIDGVVGSDEPFWKQTFSEFSTL
Mvan_4588|M.vanbaalenii_PYR-1 DAALALAERITCNAPLAVQASKRVSYGAVDGVVGSEEPFWKQTFGEFSTL
MSMEG_5198|M.smegmatis_MC2_155 DAALALAERITCNAPLAVQASKRVAYGAEEGTVPAEQPSWKRTNREFVTL
TH_4237|M.thermoresistible__bu DAALALAERITVNAPLAVQASKRVAYGAENGTVPGDENGWKLTNREFSTL
MAV_2597|M.avium_104 EAALALAERITCNAPLSVQASKRVAYGADDGIIGAEEPKWERTIREFTEL
MMAR_4317|M.marinum_M DAALALAARVTVNAPLSVRASKRIAYGVDDGVVADEERGWERTMREMRSL
MUL_0972|M.ulcerans_Agy99 DAALALAARVTVNAPLSVRASKRIAYGVDDGVVADEERGWERTMREMRSL
Rv0222|M.tuberculosis_H37Rv DAAIALAEKITANGPLAVVATKRIITESRG---WSPDTMFAEQMKILVPV
MAB_4588c|M.abscessus_ATCC_199 DTALELAAKITANGPLAVAATKRIIIESAS---WAPEEAFAKQGEILMPI
Mb3545|M.bovis_AF2122/97 TKALELADAISANGPLAVQAILRSIRETEC---MPENEAFKIDTQIGIKV
MLBr_02402|M.leprae_Br4923 PEAKAVATTISQMSRSATRMAKEAVNRSFES---TLAEGLLHERRLFHST
* :* :: . :. .
Mflv_2117|M.gilvum_PYR-GCK LKTEDAMEGPLAFAQKREPVWKAK
Mvan_4588|M.vanbaalenii_PYR-1 LKTEDAMEGPLAFAQKREPVWKAK
MSMEG_5198|M.smegmatis_MC2_155 LKTEDAMEGPLAFAQKRQPVWKAK
TH_4237|M.thermoresistible__bu LKTEDAKEGPLAFAEKREPVWKAR
MAV_2597|M.avium_104 LKSEDAKEGPLAFAEKRQPVWKAR
MMAR_4317|M.marinum_M IRSEDAKEGPLAFAQKREPVWKAR
MUL_0972|M.ulcerans_Agy99 IRSEDAKEGPLAFAEKREPVWKTR
Rv0222|M.tuberculosis_H37Rv FTSNDAKEGAIAFAERRRPRWTGT
MAB_4588c|M.abscessus_ATCC_199 FVSEDAKEGAKAFAEKRAPVWQGK
Mb3545|M.bovis_AF2122/97 FLSDDAKEGPRAFAEKRAPNFQNR
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR
: ::* ** ** ::* * :