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M. smegmatis MC2 155 MSMEG_5915 (-)

annotation: enoyl-CoA hydratase
coordinates: 5975459 - 5976259
length: 266

VSETGKGPDALVEQRGHTLIVTLNRPEARNALSGEMLSIMVEAWDRVDNDPEIRTCILTGAGGYFCSGMD
LKGADKKPPGDSFKDGSYDPSKIPGLLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISE
AKWSLYPMGGSAVRLVRQIPYTIACDMLLTGRHITAAEAKEYGLIGYVVPDGTALDKALEIAETINNNGP
LAVQAILKTIRETEGMHEDEAFGPDTRNGIPVFLSEDAKEGPRAFKEKRAPNFQMK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5915--100% (266)enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_2227-4e-4845.31% (256) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5198-2e-4639.70% (267) carnitinyl-CoA dehydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3545echA191e-12584.88% (258) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_1542-1e-12885.44% (261) enoyl-CoA hydratase
M. tuberculosis H37RvRv3516echA191e-12484.50% (258) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-3e-3134.43% (244) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_4164-1e-11880.08% (256) enoyl-CoA hydratase
M. marinum MMMAR_5002echA191e-12786.05% (258) enoyl-CoA hydratase EchA19
M. avium 104MAV_0643-1e-12887.21% (258) enoyl-CoA hydratase
M. thermoresistible (build 8)TH_1820echA191e-13187.22% (266) POSSIBLE ENOYL-CoA HYDRATASE ECHA19 (ENOYL HYDRASE)
M. ulcerans Agy99MUL_4076echA191e-12685.27% (258) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_5216-1e-13991.73% (266) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3545|M.bovis_AF2122/97            ------------------------MESGPDALVERRGHTLIVTMNRPAAR
Rv3516|M.tuberculosis_H37Rv         ------------------------MESGPDALVERRGHTLIVTMNRPAAR
MMAR_5002|M.marinum_M               -------------MAPNTSETPANGESGPDALVEQRGHTLIVTMNRPSRR
MUL_4076|M.ulcerans_Agy99           ---MPDVMRKAVLVAPNTSETPANGESGPDALVEQRGHTLIVTMNRPSRR
MAV_0643|M.avium_104                -----------------MAEASANEKTGPDALVEQRGHTLIVTLNRPHAR
MSMEG_5915|M.smegmatis_MC2_155      ------------------MSE---TGKGPDALVEQRGHTLIVTLNRPEAR
Mvan_5216|M.vanbaalenii_PYR-1       ------------------MSD---PQKGPDALVEQRGHTLIVTLNRPEAR
Mflv_1542|M.gilvum_PYR-GCK          MLHFQTSLWHRRWKADQFVSDEQNPEKAPDALVEQRGHTLIVTMNRPEKR
TH_1820|M.thermoresistible__bu      --------------VDQPVSA---LGSQPHALIEQRGHTLILTLNRPEAR
MAB_4164|M.abscessus_ATCC_1997      -------MTEADALRASGSSHTVTEQDAPHALVELRDHVLIVTMNRPHAR
MLBr_02402|M.leprae_Br4923          -------------------------MKYDTILVDGYQRVGIITLNRPQAL
                                                                   *::   :. *:*:***   

Mb3545|M.bovis_AF2122/97            NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPP
Rv3516|M.tuberculosis_H37Rv         NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPP
MMAR_5002|M.marinum_M               NALSGEMMQIMVEAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATKKPP
MUL_4076|M.ulcerans_Agy99           NALSGEMMQIMVEAWDRVDNDPDIRCCILTGAGDYFCAGMDLKAATKKPP
MAV_0643|M.avium_104                NALSTEMMEIMVQAWDRVDNDDDIRCCILTGAGGYFCAGMDLKAATKKPP
MSMEG_5915|M.smegmatis_MC2_155      NALSGEMLSIMVEAWDRVDNDPEIRTCILTGAGGYFCSGMDLKGADKKPP
Mvan_5216|M.vanbaalenii_PYR-1       NALSTEMLSIMVDAWNRVDEDPEIRTCILTGAGGYFCAGMDLKAASKKPP
Mflv_1542|M.gilvum_PYR-GCK          NALSAEMMQIMVEAWDRVDSDPEIRSCILTGAGGAFCAGMDLKKADSQAP
TH_1820|M.thermoresistible__bu      NALSTEMLATMVEAWDRVDNDPEIRTCILTGAGGYFCSGMDLKAATARPP
MAB_4164|M.abscessus_ATCC_1997      NALSGEMLEIMTQAWDRVDNDPEVRVCILTGAGGYFCAGADLKAMNKRAP
MLBr_02402|M.leprae_Br4923          NALNSQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTF
                                    ***. :*:  :.:* ..:* * ::   ::**:   *.:* *:*     . 

Mb3545|M.bovis_AF2122/97            GDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
Rv3516|M.tuberculosis_H37Rv         GDSFKDGSYGPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
MMAR_5002|M.marinum_M               GDSFKDGSYDPSRIDALLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV
MUL_4076|M.ulcerans_Agy99           GDSFKDGSYDPSRIDALLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV
MAV_0643|M.avium_104                GESFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
MSMEG_5915|M.smegmatis_MC2_155      GDSFKDGSYDPSKIPGLLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
Mvan_5216|M.vanbaalenii_PYR-1       GDSFADGSYDPSKIEGLLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV
Mflv_1542|M.gilvum_PYR-GCK          GDSFKDGSYDPSKIPALLKGRRLKKPLIAAVEGAAIAGGTEILQGTDIRV
TH_1820|M.thermoresistible__bu      GDSFKDGSYDPSTIPALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRI
MAB_4164|M.abscessus_ATCC_1997      GDQFSDGSYDPSVIPGLLKGRRLTKPLIAAVEGPAIAGGTEILQATDIRV
MLBr_02402|M.leprae_Br4923          TDAFDADFFS-----AWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLI
                                     : *  . :.     .  *   : .*:**** * *:.** *:    *: :

Mb3545|M.bovis_AF2122/97            AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEA
Rv3516|M.tuberculosis_H37Rv         AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEA
MMAR_5002|M.marinum_M               AAESAKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA
MUL_4076|M.ulcerans_Agy99           AAESAKFGISEAEWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA
MAV_0643|M.avium_104                AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA
MSMEG_5915|M.smegmatis_MC2_155      AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTIACDMLLTGRHITAAEA
Mvan_5216|M.vanbaalenii_PYR-1       AGESAKFGISEAKWSLYPMGGSAVRLPRQIPYTIACDLLLTGRHITAAEA
Mflv_1542|M.gilvum_PYR-GCK          AGESAKFGVSEAKWSLYPMGGSAVRLVRQIPYTVACDILLTGRHISAAEA
TH_1820|M.thermoresistible__bu      AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTIAADLLLTGRHITAAEA
MAB_4164|M.abscessus_ATCC_1997      AGESAKFGVSEVKWSLYPMGGSAVRLPRQIPYTVACDILLTGRHIKAPEA
MLBr_02402|M.leprae_Br4923          AADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEA
                                    *.::**** .* : .: *  *.: ** * *  : * *::**** * *.**

Mb3545|M.bovis_AF2122/97            KEMGLIGHVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPEN
Rv3516|M.tuberculosis_H37Rv         KEMGLIGHVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPEN
MMAR_5002|M.marinum_M               KEMGLVGHVVPDGQALTKALEIAEIIAANGPLAVQAILRTIRETEGMHEN
MUL_4076|M.ulcerans_Agy99           KEMGLVGHVVPDGQALTKALEIAEIIAANGPLAVQAILRTIRETEGMHEN
MAV_0643|M.avium_104                KEMGLIGHVVPDGQALAKALEIAEVIENNGPLAVQAILRAIRETEGMHEN
MSMEG_5915|M.smegmatis_MC2_155      KEYGLIGYVVPDGTALDKALEIAETINNNGPLAVQAILKTIRETEGMHED
Mvan_5216|M.vanbaalenii_PYR-1       LQYGLIGHVVPDGTALDKALEIAEVINNNGPLAVQAILKTIRETEGMHEE
Mflv_1542|M.gilvum_PYR-GCK          KEFGLIGHVVPDGQALTKALEIAEVINGNGPLAVQAILKTIRETEGMHEE
TH_1820|M.thermoresistible__bu      KEIGLIGYVVPDGTALDKALEIAEVINNNGPLAVQAILRSIRETEGLPEN
MAB_4164|M.abscessus_ATCC_1997      KDIGLIGHVVPDGQALEKALELANMIAGNGPLAVQAVLKTIRDSEGMHEN
MLBr_02402|M.leprae_Br4923          ERSGLVSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLA
                                       **:. **  .  * :*  :*  *   .  *.:   .::. :      

Mb3545|M.bovis_AF2122/97            EAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
Rv3516|M.tuberculosis_H37Rv         EAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
MMAR_5002|M.marinum_M               EAFKIDTRIGIEVFLSDDAKEGPQAFAQKRKPNFQNR
MUL_4076|M.ulcerans_Agy99           EAFKIDTRIGIEVFLSDDAKEGPQAFAQKRKPNFQNR
MAV_0643|M.avium_104                EAFKIDTQIGIKVFLSEDAKEGPRAFAEKRKPNFQNR
MSMEG_5915|M.smegmatis_MC2_155      EAFGPDTRNGIPVFLSEDAKEGPRAFKEKRAPNFQMK
Mvan_5216|M.vanbaalenii_PYR-1       EAFKPDTANGIPVFLSEDAKEGPRAFKEKRAPNFQMK
Mflv_1542|M.gilvum_PYR-GCK          EAFKPDTANGIPVFLSEDSKEGPKAFLEKRKPVWKLK
TH_1820|M.thermoresistible__bu      EAFKIDTKIGIEVFLSEDAKEGPRAFKEKRKPVFKMK
MAB_4164|M.abscessus_ATCC_1997      EAFKADTKVGIGVFTSNDAKEGPRAFAEKRAPNFTGS
MLBr_02402|M.leprae_Br4923          EGLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR
                                    *.:  :      .* ::* .**  ** :** * :