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MTRTRLFRFGSAVASTLTVAALALSACAPGPSGDSGSSPAPTGEVSKDIASAGPVTLTVWDQNTDGGIRE AQEKLNAQFQEMYPNVTIKRTVESFSDLKTTLRLALSSNTPPDVVQANQGYPDMGAFVAAGMLRPMSDYA ELYGWNTYYPEALLKQNSFSSDGKTWQGDTLYGVSQTGEVVGIFYNRELLSSLGLEVPKTLDDLNAAMEA AKAKNILPMAFGNLDKSPGIHVYGVVQAALAGAPAVNDLVSGKGGAWTDEPSLKAAQQIADWSTKGYLTP GANGVSRDDAIAEFGRGGALFTITGTWMQQPLQDALGDKAGFTTLTSDQGEPATTGGQGLAWAITSKSAH PDVAAAYIDFITNAKASQLLLDTGNLPTVLPSGYEPEAGTVAADIATQYRDVQEANGEVPYLDYATPTFY DTITAAMQELVGGQATPEQFVDTLQKDYADFLASQK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0505 | - | - | 100% (456) | sugar ABC transporter, substrate-binding protein, putative |
| M. smegmatis MC2 155 | MSMEG_3111 | - | 1e-11 | 23.81% (420) | extracellular solute-binding protein, family protein 1 |
| M. smegmatis MC2 155 | MSMEG_5145 | - | 9e-11 | 21.35% (459) | extracellular solute-binding protein, family protein 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2345 | uspC | 6e-06 | 22.78% (395) | periplasmic sugar-binding lipoprotein UspC |
| M. gilvum PYR-GCK | Mflv_3775 | - | 4e-13 | 25.06% (447) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv2318 | uspC | 3e-06 | 23.04% (395) | periplasmic sugar-binding lipoprotein UspC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1715c | - | 3e-05 | 25.53% (188) | sugar ABC transporter, sugar-binding protein |
| M. marinum M | MMAR_3619 | uspC | 6e-08 | 23.70% (384) | periplasmic sugar-binding lipoprotein UspC |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1246 | uspC | 4e-08 | 23.70% (384) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | Mvan_2624 | - | 1e-12 | 26.40% (356) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3619|M.marinum_M ------MSRPRFSTLVAVAVTLIAALLGVTAVALDRIDAPPGGKIVVTVR
MUL_1246|M.ulcerans_Agy99 ------MNRPRFSTLVAVAVTLIAALLGVTAVALDRIDAPPGGKIVVTVR
Mb2345|M.bovis_AF2122/97 ------MTRPRQSTLVATALVLVAILLGVTAVLLGLSAEPRGGKIVVTVR
Rv2318|M.tuberculosis_H37Rv ------MTRPRQSTLVATALVLVAILLGVTAVLLGLSAEPRGGKIVVTVR
MAB_1715c|M.abscessus_ATCC_199 ---------MKASTRAALTLALVALLLFGVAAWLGIPTTPHG-KTVVTVR
Mflv_3775|M.gilvum_PYR-GCK MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSACAGSGGPEQAESTG
Mvan_2624|M.vanbaalenii_PYR-1 MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEATG
MSMEG_0505|M.smegmatis_MC2_155 ---MTRTRLFRFGSAVASTLTVAALALSACAPGPSGDSGSSPAPTGEVSK
: . : : * .
MMAR_3619|M.marinum_M ---------------LWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFST
MUL_1246|M.ulcerans_Agy99 ---------------LWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFST
Mb2345|M.bovis_AF2122/97 ---------------LWDEPIAAAYRQSFAAFTRSHPDIEVRTNLVAYST
Rv2318|M.tuberculosis_H37Rv ---------------LWDEPIAAAYRQSFAAFTRSHPDIEVRTNLVAYST
MAB_1715c|M.abscessus_ATCC_199 ---------------VWDQQVAEAYRGSFDEFSRRNPDIQVAVTVTSYAS
Mflv_3775|M.gilvum_PYR-GCK SGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYPGVEINIESLTFDQ
Mvan_2624|M.vanbaalenii_PYR-1 TGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYPGVEINIESLTFDQ
MSMEG_0505|M.smegmatis_MC2_155 DIASAGPVTLTVWDQNTDGGIREAQEKLNAQFQEMYPNVTIKRTVESFSD
. * *.: : ::
MMAR_3619|M.marinum_M YFDTLRTDVAGGS-ADDIFWLSN--AYLAAYADSGRLMKIDTAV------
MUL_1246|M.ulcerans_Agy99 YFDTLRTDVAGGS-ADDIFWLSN--AYLAAYADSGRLMKIDTAV------
Mb2345|M.bovis_AF2122/97 YFETLRTDVAGGS-ADDIFWLSN--AYFAAYADSGRLMKIQT--------
Rv2318|M.tuberculosis_H37Rv YFETLRTDVAGGS-ADDIFWLSN--AYFAAYADSGRLMKIQT--------
MAB_1715c|M.abscessus_ATCC_199 YFNSLRTDVAGHG-ADDIFWLSN--AYLSDYADTGNLVPVEP--------
Mflv_3775|M.gilvum_PYR-GCK MRDKLVSSFQSSSPAYDLIVVDN--PWMVDFANAKFLQPLDARIDSTPDY
Mvan_2624|M.vanbaalenii_PYR-1 MRDKLVSSFQSSSPTYDLIVVDN--PWMVDFANAKFLQPLDARIDSTPDY
MSMEG_0505|M.smegmatis_MC2_155 LKTTLRLALSSNT-PPDVVQANQGYPDMGAFVAAGMLRPMSDYAELYGWN
.* . . . *:. .: . : :. : * :.
MMAR_3619|M.marinum_M DPGEWEPAVVDQFTRNG------VLWGVPQLTDAGIAVFYNADLLAAAGV
MUL_1246|M.ulcerans_Agy99 DPGEWEPAVVDQFTRNG------VLWGVPQLTDAGIAVFYNADLLAAAGV
Mb2345|M.bovis_AF2122/97 DAADWEPAVVDQFTRSG------VLWGVPQLTDAGIAVFYNADLLAAAGV
Rv2318|M.tuberculosis_H37Rv DAADWEPAVVDQFTRSG------VLWGVPQLTDAGIAVFYNADLLAAAGV
MAB_1715c|M.abscessus_ATCC_199 -RADWDPSVVAQFTRDG------KLWGVPQLSDAGIALYYNKNLLDAAQV
Mflv_3775|M.gilvum_PYR-GCK DAGDFFTPLTDITTVDG------TRYGVPFYNYALGYLYNADDLAAANQQ
Mvan_2624|M.vanbaalenii_PYR-1 DAADFFKPLTDITTVDG------ARYGVPFYNYALGYLYNADDLTAANQQ
MSMEG_0505|M.smegmatis_MC2_155 TYYPEALLKQNSFSSDGKTWQGDTLYGVSQTGEVVGIFYNRELLSSLGLE
: .* :**. . .: *
MMAR_3619|M.marinum_M DPAELDGLRWSPGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGY
MUL_1246|M.ulcerans_Agy99 DPAELDGLRWSPGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGY
Mb2345|M.bovis_AF2122/97 DPTQVDNLRWSRGDD-DTLRPMLARLTVDADGRTANTPGFDARRVRQWGY
Rv2318|M.tuberculosis_H37Rv DPTQVDNLRWSRGDD-DTLRPMLARLTVDADGRTANTPGFDARRVRQWGY
MAB_1715c|M.abscessus_ATCC_199 DPAELAELRWDPDPEVDTLRPMLHRLTAPG----------------HWGY
Mflv_3775|M.gilvum_PYR-GCK VPTTLDELVSTSKALKSGDRAGIAMQ-------------------PQRGY
Mvan_2624|M.vanbaalenii_PYR-1 VPTTLDELVSTSKALKSGDRAGIAMQ-------------------PQRGY
MSMEG_0505|M.smegmatis_MC2_155 VPKTLDDLNAAMEAAKAKNILPMAFGNLD----------------KSPGI
* : * : *
MMAR_3619|M.marinum_M NAANDPQAIYLNYIGSAGGVFMRDNEFAFDNPPAIDAFRYLVGLINNDHV
MUL_1246|M.ulcerans_Agy99 NAANDPQAIYLNYIGSAGGVFMRDNEFAFDNPPAIDAFRYLVGLINNDHV
Mb2345|M.bovis_AF2122/97 NAANDPQAIYLNYIGSAGGVFQRDGKFAFDNPGAIEAFRYLVGLINDDHV
Rv2318|M.tuberculosis_H37Rv NAANDPQAIYLNYIGSAGGVFQRDGKFAFDNPGAIEAFRYLVGLINDDHV
MAB_1715c|M.abscessus_ATCC_199 NAANDLQGIYLNYLGSAGAVFQADDKFAFAKPRAEMAFTYLVDLINVDRV
Mflv_3775|M.gilvum_PYR-GCK KIFEEWGNWLF---AAGGSIYDADGKITLNTP---EAKRALEAYIDTYNT
Mvan_2624|M.vanbaalenii_PYR-1 KIFEEWGNWLF---AAGGSIYDADGKITLNTP---EAKRALEAYIDTYNT
MSMEG_0505|M.smegmatis_MC2_155 HVYGVVQAALAGAPAVNDLVSGKGG--AWTDEPSLKAAQQIADWSTKGYL
: . . : .. : * :
MMAR_3619|M.marinum_M APPASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDATFRWGVAMLP
MUL_1246|M.ulcerans_Agy99 APPASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDATFRWGVAMLP
Mb2345|M.bovis_AF2122/97 APPASDTNDNGDFSRNQFLAGKMALFQSGTYSLAPVARDALFHWGVAMLP
Rv2318|M.tuberculosis_H37Rv APPASDTNDNGDFSRNQFLAGKMALFQSGTYSLAPVARDALFHWGVAMLP
MAB_1715c|M.abscessus_ATCC_199 APSAADTNDNNDFSRNQFLQGRMALFQSGTYNLAQIQANATFPWDVAMMP
Mflv_3775|M.gilvum_PYR-GCK AAPANSLSWGMDEAQRSVSANQSASMINYNWQLPALNEPGSGPAAGKIKL
Mvan_2624|M.vanbaalenii_PYR-1 AAPANSLSWGMDEAQRSVSANQAASMINYNWQLPALNEPGSGPAAGKIKL
MSMEG_0505|M.smegmatis_MC2_155 TPGANGVSR--DDAIAEFGRGGALFTITGTWMQQPLQDALGDKAGFTTLT
:. * . . * : .. . . .: :
MMAR_3619|M.marinum_M IGPAGRVSVTN-GIAAAGNSASQHPDAVRQVLAWMGSSAGNEYLGRDGVA
MUL_1246|M.ulcerans_Agy99 IGPAGRVSVTN-GIAAAGNSASQHPDAVRQVLAWMGSSAGNEYLGRDGVA
Mb2345|M.bovis_AF2122/97 AGPAGRVSVTN-GIAAAGNSASKHPDAVRQVLAWMGSTEGNSYVGRHGAA
Rv2318|M.tuberculosis_H37Rv AGPAGRVSVTN-GIAAAGNSASKHPDAVRQVLAWMGSTEGNSYLGRHGAA
MAB_1715c|M.abscessus_ATCC_199 AGPQGRVSVTN-GIVAAANSSSPHPDAVHKVLAWMGSTDGNSFLGRSGSA
Mflv_3775|M.gilvum_PYR-GCK ATIPGGKQVLG-SWSWAIPANSATPDAAWAFVSWITAKPNDVVRTEKGGA
Mvan_2624|M.vanbaalenii_PYR-1 ATIPGGKQVLG-SWSWAIPANSATPDAAWAFVSWITAKPNDVVRTEKGGA
MSMEG_0505|M.smegmatis_MC2_155 SDQGEPATTGGQGLAWAITSKSAHPDVAAAYIDFITNAKASQLLLDTGNL
. . . * : * **.. : :: . *
MMAR_3619|M.marinum_M IPAVRSAQPSYFAFWEAKGVNVEPFFAVLSGSRIPAPGGAGFAAGNDALK
MUL_1246|M.ulcerans_Agy99 IPAVRSAQPSYFAFWEAKGVNVNPFFAVLSGSRIPAPGGAGFAAGNDALK
Mb2345|M.bovis_AF2122/97 IPAVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGGAGFAAGQQALE
Rv2318|M.tuberculosis_H37Rv IPAVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGGAGFAAGQQALE
MAB_1715c|M.abscessus_ATCC_199 IPAVLSARAPYFQYWADKGVDVSPFFEVLRGQQIAAPGGQGFGAGFAALK
Mflv_3775|M.gilvum_PYR-GCK AIRKSTLQNP-AVLQGQFGEEYYRTVEQLLADAAPLTQGPSGEEMIQAVG
Mvan_2624|M.vanbaalenii_PYR-1 AIRQSTLQDP-AVLGGQFGEEYYRTVEQLLANAAPLTQGPSGEEMIQAVG
MSMEG_0505|M.smegmatis_MC2_155 PTVLPSGYEPEAGTVAADIATQYRDVQEANGEVPYLDYATP--TFYDTIT
: . . . ::
MMAR_3619|M.marinum_M PYFDEMFLGRGQVATILREAQAAANAAARR--
MUL_1246|M.ulcerans_Agy99 PYFDEMFLGRGQVATILREAQAAANAAARR--
Mb2345|M.bovis_AF2122/97 PYFDEMFLGRGDVTTTLRQAQAAANAATQR--
Rv2318|M.tuberculosis_H37Rv PYFDEMFLGRGDVTTTLRQAQAAANAATQR--
MAB_1715c|M.abscessus_ATCC_199 PYFAEMFLGRLDVREALQQAQRAANRALER--
Mflv_3775|M.gilvum_PYR-GCK TALNEAVAGEKSVDDALATAQAEAEKIQG---
Mvan_2624|M.vanbaalenii_PYR-1 TELNEAVAGKKSVDDALAAAQAEAEKIQG---
MSMEG_0505|M.smegmatis_MC2_155 AAMQELVGGQATPEQFVDTLQKDYADFLASQK
. : * . *. : *