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LPPLPAEDWDDAARDALASVVPPERRDADGVGNALGVLVRHPELARHFLQFNNYLQRDSLLPERIRELVI LRTAYRAGCVYEWGHHAAMGLLAGLTVDDVESARSGSAADEFDQTVLDATDELVAGAQLSPETWTRLGRW LDDRQRMDLMFTVGGYLTLAMALNTFEVQLEEGAGRPEFYAPVGTAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6536 | - | - | 100% (188) | carboxymuconolactone decarboxylase |
| M. smegmatis MC2 155 | MSMEG_4839 | - | 2e-47 | 52.60% (173) | carboxymuconolactone decarboxylase |
| M. smegmatis MC2 155 | MSMEG_0905 | pcaC | 3e-12 | 31.16% (138) | hypothetical protein MSMEG_0905 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 1e-14 | 32.39% (142) | hypothetical protein Mb1558 |
| M. gilvum PYR-GCK | Mflv_2440 | - | 1e-41 | 48.24% (170) | carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv1531 | - | 1e-14 | 32.39% (142) | hypothetical protein Rv1531 |
| M. leprae Br4923 | MLBr_02465 | - | 6e-09 | 29.06% (117) | hypothetical protein MLBr_02465 |
| M. abscessus ATCC 19977 | MAB_4119 | - | 4e-10 | 28.35% (127) | hypothetical protein MAB_4119 |
| M. marinum M | MMAR_4743 | - | 6e-48 | 51.16% (172) | hypothetical protein MMAR_4743 |
| M. avium 104 | MAV_3958 | pcaC | 3e-43 | 49.42% (172) | hypothetical protein MAV_3958 |
| M. thermoresistible (build 8) | TH_2018 | - | 5e-48 | 53.18% (173) | carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 5e-09 | 31.40% (121) | hypothetical protein MUL_4533 |
| M. vanbaalenii PYR-1 | Mvan_4212 | - | 8e-45 | 50.58% (172) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 --------MTTSRVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLN
Rv1531|M.tuberculosis_H37Rv --------MTTSRVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLN
MMAR_4743|M.marinum_M --------MRLPPLPADQWDEAVQRSLSVILPAQRCNPRDAGNALSTFAN
TH_2018|M.thermoresistible__bu --------VRLAPLPAEQWDDEVLSALAVMLPEERRNPDGAGTALSTLVR
Mflv_2440|M.gilvum_PYR-GCK --------MRVAPLPADQWDDTVDKALSGLMPEEMRNPETAGNLVATLVR
Mvan_4212|M.vanbaalenii_PYR-1 --------MRLAPLPADQWDGVAEQALSGLMPAELRNPETAGNLVGTLLR
MAV_3958|M.avium_104 MAASDRHPQRLTPLPADEWDEDTRAALASLIPAERANPVGAGNVLSTLVR
MSMEG_6536|M.smegmatis_MC2_155 ---------MLPPLPAEDWDDAARDALASVVPPERRDADGVGNALGVLVR
MLBr_02465|M.leprae_Br4923 -MSGGTGTGPVGRIPPGSLRQLGPINWVIAKLAASLLRTSEMHLFTILGQ
MUL_4533|M.ulcerans_Agy99 -MTG----DQVARIPSGGIRQLGPVNWALAKLAARSVRAPEMHLFTALGY
MAB_4119|M.abscessus_ATCC_1997 -MSS-------GRIPSGGLRELGPINWVIAKGMARAVNAPEMHLATTLGQ
:* :
Mb1558|M.bovis_AF2122/97 HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
Rv1531|M.tuberculosis_H37Rv HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
MMAR_4743|M.marinum_M HPALAKAFLRFNTHLLFASTLPARVRELAILRVAHRRACAYEWTHHVALA
TH_2018|M.thermoresistible__bu HPRLTKAFLRFSNHLLFRSTLPPRLRELAVLRVAHRRSCDYEWAHHVFIG
Mflv_2440|M.gilvum_PYR-GCK HPRLAKGFLRFNFHLLYGSSLPARLRELAVLRIAHLTKCEYEWLHHVEMG
Mvan_4212|M.vanbaalenii_PYR-1 HPKLARAFLRFNFQLLYGTTLPERLREFVVLRVARLSNCEYEWRHHVAMG
MAV_3958|M.avium_104 HPDLTAAYLPFNAYLLTRSTLSPRIREVALLRVVHRSKCGYLWSHHLPIA
MSMEG_6536|M.smegmatis_MC2_155 HPELARHFLQFNNYLQRDSLLPERIRELVILRTAYRAGCVYEWGHHAAMG
MLBr_02465|M.leprae_Br4923 RQLLFWAWLIYGGRLLRG-KLPRVDTELVILRVAHLRTCEYELQHHRRMA
MUL_4533|M.ulcerans_Agy99 RQYLFWTWAIYSGRLLHG-RLPRIDTELVILRVAHLRSCEYELQHHRRMA
MAB_4119|M.abscessus_ATCC_1997 TGARFWPWLAYSGAILRGTKLSTRDTEVVILRVAHVRECEYELQHHTRIA
: : * *..::* * * :* :.
Mb1558|M.bovis_AF2122/97 SGLGVSADDLLGVRDWQGYNGFGP-------AEQAVLAATDDVVREGAVS
Rv1531|M.tuberculosis_H37Rv SGLGVSADDLLGVRDWQGYNGFGP-------AEQAVLAATDDVVREGAVS
MMAR_4743|M.marinum_M EQAGISGDEIAAVRRGEATDDF----------ERAVLTGVDELDENSELS
TH_2018|M.thermoresistible__bu KAEGLTDDDIAGVQRGAVDDPF----------DQAVLDAVDELEEHYRIS
Mflv_2440|M.gilvum_PYR-GCK REAGLSDDVIDGITRGEATDGL----------DRAVLNAVDELQNDSVVS
Mvan_4212|M.vanbaalenii_PYR-1 RDAGLSDDVIAGIERGEAVDEF----------DRAVLTAVDELHHDSVIS
MAV_3958|M.avium_104 RRAGLSESDIDDIRRGRCADPT----------DAAVVRAVDELTGESTLS
MSMEG_6536|M.smegmatis_MC2_155 LLAGLTVDDVESARSGSAADEF----------DQTVLDATDELVAGAQLS
MLBr_02465|M.leprae_Br4923 RKRGLDTKIQAMIFAWPDVPTGAG----LSVRQQALLAATDEFVKDRKIT
MUL_4533|M.ulcerans_Agy99 RAAGLDAHAQATIFAWPDAPQGDGPRRVLSSRQQALLTATDELIKNRSVT
MAB_4119|M.abscessus_ATCC_1997 KSAGIDPAYQERIFTG---AGAEG----LSDKERALITGVDEILTTRTLS
*: : ::: ..*:. ::
Mb1558|M.bovis_AF2122/97 AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
Rv1531|M.tuberculosis_H37Rv AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
MMAR_4743|M.marinum_M DQTWAALG--EHLDDRQRMDYVFTVGCYALLAMAFNTFGVQLEELEQDRA
TH_2018|M.thermoresistible__bu DATWATLG--ARLDERQLMDLVFTVGCYGLMAMAYNTFGITPETGR----
Mflv_2440|M.gilvum_PYR-GCK DATWTALS--DHLDERQLMDLVFTIGCYGALAMAINTFGVEPDQER----
Mvan_4212|M.vanbaalenii_PYR-1 DSTWTALS--SHLDERQLMDLVFTIGCYGALAMAINTFGVEPDQER----
MAV_3958|M.avium_104 RQTWDRLC--ELFTQRQCMDLIFTIGGYLLLALAVNTFGVQEEEETR---
MSMEG_6536|M.smegmatis_MC2_155 PETWTRLG--RWLDDRQRMDLMFTVGGYLTLAMALNTFEVQLEEGAGRPE
MLBr_02465|M.leprae_Br4923 SSSWQQLE--THLDRRRLIEFCMLISQYDGLAATISSLDIPLDNSC----
MUL_4533|M.ulcerans_Agy99 PATWEQLE--IHLNRRRLIEFCLLATQYDALAATITALGVPLDNPR----
MAB_4119|M.abscessus_ATCC_1997 DEAWEGLS--KFLDRRQLIGFCLLVTQYDGLAATMSSLRIPLDH------
:* : : :* :: : :
Mb1558|M.bovis_AF2122/97 PDGLSPR--
Rv1531|M.tuberculosis_H37Rv PDGLSPR--
MMAR_4743|M.marinum_M ER-------
TH_2018|M.thermoresistible__bu ---------
Mflv_2440|M.gilvum_PYR-GCK ---------
Mvan_4212|M.vanbaalenii_PYR-1 ---------
MAV_3958|M.avium_104 ---------
MSMEG_6536|M.smegmatis_MC2_155 FYAPVGTAR
MLBr_02465|M.leprae_Br4923 ---------
MUL_4533|M.ulcerans_Agy99 ---------
MAB_4119|M.abscessus_ATCC_1997 ---------