For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4593 (-)

annotation: acyl-CoA dehydrogenase
coordinates: 4684539 - 4685030
length: 163

MTALDDLIRIAADEGFDPARRWPVAADFGVAHILSDLARQAAHRDAMRESPADDVRRLQQAGVPALRLPT
ELGGRGIPLTQLFAFAAELADADPSVAHALRNHFWFVEQALRSAPDSPRRAYLARVADGDLIGGSFGELH
TSKAGNTEVTLRQALRSSSWDSR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4593--100% (163)acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_5001-1e-2141.23% (114) pesticide degrading monooxygenase
M. smegmatis MC2 155MSMEG_4084-5e-1837.98% (129) putative acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1422c-2e-2339.04% (146) putative acyl-CoA dehydrogenase
M. marinum M-----
M. avium 104MAV_3422-8e-1135.90% (117) acyl-CoA dehydrogenase domain-containing protein
M. thermoresistible (build 8)TH_3721-2e-1536.03% (136) PUTATIVE putative acyl-CoA dehydrogenase family protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0356-2e-0629.89% (87) acyl-CoA dehydrogenase type 2

CLUSTAL 2.0.9 multiple sequence alignment


MAB_1422c|M.abscessus_ATCC_199      ---------MTSAPSVLEIRALPGTDTYRNLLAQVAEGARDR-----DLD
MAV_3422|M.avium_104                ---------MPVAFHRQDT--PAGAAAVQPVLAEIAADYRLR-----LAD
TH_3721|M.thermoresistible__bu      ------------VPYFDEQRFEALAAEFRPVFDRIRAGAVQR-----ERD
MSMEG_4593|M.smegmatis_MC2_155      MTALDDLIRIAADEGFDPARRWPVAADFGVAHILSDLARQAA-----HRD
Mvan_0356|M.vanbaalenii_PYR-1       -MTGSIGTNRSTIKGVTMLEQDLTDEDFAPYFVKAQEVSQFFREIGPKYD
                                                                                     *

MAB_1422c|M.abscessus_ATCC_199      --DENPFDQVRLLKEAGFGRLRIPTELGGAGLSVRQLFSAIIDVAQADPI
MAV_3422|M.avium_104                GGTEPPLRGLKLVRDHRLGALRLARELGGAGYTAPEFFDYLVALAAADPD
TH_3721|M.thermoresistible__bu      --RELPFEQIGWLKAAGFGAVRLPVSAGGRGATIPELTRLLIELSTADSN
MSMEG_4593|M.smegmatis_MC2_155      AMRESPADDVRRLQQAGVPALRLPTELGGRGIPLTQLFAFAAELADADPS
Mvan_0356|M.vanbaalenii_PYR-1       QENTFAYPSIEVFKKSGLGALPVPKAFGGPGGNILQVSKVVSELSKGDSA
                                         .   :  .:   .  : :.   ** *    :.      :: .*. 

MAB_1422c|M.abscessus_ATCC_199      VAHIFRTHFWFVEERLRTLADPVSAAWLTKVNEGNLFANAFSEKGSLAVG
MAV_3422|M.avium_104                LAHILRIHYALVEELQVTPRRPGSDRWIAVVAEGGLIGGANAEQSQKSVG
TH_3721|M.thermoresistible__bu      ITQALRGHFAFAEDRLVAAPGPGRDRWWQRFAAGDLAGNAWTEIGDVVLG
MSMEG_4593|M.smegmatis_MC2_155      VAHALRNHFWFVEQALRSAPDSPRRAYLARVADGDLIGGSFGELHTSKAG
Mvan_0356|M.vanbaalenii_PYR-1       ITLAYNMHYIMVGIAGNLMSEEQNKYWLGRVADGELMFGPFSEQRAGFSG
                                    ::   . *: :.              :   .  * *  ..  *      *

MAB_1422c|M.abscessus_ATCC_199      SLVFNTRLLPVGDAYRLNGEKFYSTGTLFADYLTVTAT-TDRDSVASVIV
MAV_3422|M.avium_104                GNHRDTRLVTTPDGLRLRGRKFYSTGAQFSDYLRITAQ-DDDGAPTAVVI
TH_3721|M.thermoresistible__bu      EANTKVAPSGDPGTFVVNGQKFYSTGSIFADWIDLYAQRTDTGEFVIAAV
MSMEG_4593|M.smegmatis_MC2_155      NTEVTLRQALRSSSWDSR--------------------------------
Mvan_0356|M.vanbaalenii_PYR-1       LADMQAVPQ-KDGGWKLYGKKTWGTLCEAADIITTNATETDADGNLPDTF
                                                .                                     

MAB_1422c|M.abscessus_ATCC_199      P------------------GDRDGVRLVDDWDGFGQRRTGTGTTIFSQVD
MAV_3422|M.avium_104                P------------------VDRAGVEHLDDWDGIGQRQTGSGTTVFNDVA
TH_3721|M.thermoresistible__bu      D------------------AHADGVTHADDWDGFGQRTTGSGTSTYRDVR
MSMEG_4593|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0356|M.vanbaalenii_PYR-1       DGRVAAEKLFIGDFKVDENGVGDGIRIEKTWDALGMHATGTQTIVFDGYF
                                                                                      

MAB_1422c|M.abscessus_ATCC_199      VAADEILSETPYDAAPVPTTQYASLQLYILAIVAGVLRAVVDDGEALLRS
MAV_3422|M.avium_104                VADDEVFPLG--STIGVNRARGALVQLYLHAVAAGILRSLTEDAAALVRG
TH_3721|M.thermoresistible__bu      VPAENLIPFAT-----RFRYQTAFYQLFHLATLAGIAHAATAELAQRVRG
MSMEG_4593|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0356|M.vanbaalenii_PYR-1       VPEDGFVSVWRAGAFGVLEWASLMFASIYLGMQQRILEESVKSLSKKHLG
                                                                                      

MAB_1422c|M.abscessus_ATCC_199      RQRNFSHALTERPVDDPLLQRTLGELSATAFAAEATVLAAADAIEAATAT
MAV_3422|M.avium_104                RRRTYTFASADTPTADPQLLQIVGEIDAVAYTAHALVRNAAAELAPALQA
TH_3721|M.thermoresistible__bu      RTRTFSHGNAPRYAADPQIQQVVGEVMAAAFAAEAIALRAAEDXXXRRRS
MSMEG_4593|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0356|M.vanbaalenii_PYR-1       ATFGAIVAADTEVKSVGHIIDGIGDMASRVECSRRVLYQTCQDLLDGKDK
                                                                                      

MAB_1422c|M.abscessus_ATCC_199      LRDGVPDAQLAQEAQVAVAKAKVHIDAVALDAATKLLDLGGASAASRTRN
MAV_3422|M.avium_104                ARDTGIDPELEAAASIAAARVKVAIQEPALRAASRVFDAGGASAVQASAL
TH_3721|M.thermoresistible__bu      SAAPPRRRTRPRSCWDATRSSSVCVPRSRPPRCTSPWAPRPMSG------
MSMEG_4593|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0356|M.vanbaalenii_PYR-1       LWAPELRFPYLGLAKTFIAGNVMHMSRQAMSMVGGQSFRRGGIFERLYR-
                                                                                      

MAB_1422c|M.abscessus_ATCC_199      LDRHWRNIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF
MAV_3422|M.avium_104                LDRHWRNLRTLFSHNPTVYKARVLGDVVVNGAALPDTSFF
TH_3721|M.thermoresistible__bu      ----------------------------------------
MSMEG_4593|M.smegmatis_MC2_155      ----------------------------------------
Mvan_0356|M.vanbaalenii_PYR-1       -----DSAASMFQPLNGDQTRTYIGQFLLESAAAQNGASS