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M. smegmatis MC2 155 MSMEG_4097 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 4174286 - 4175515
length: 409

TSTQPTELDEALVRIRAVFDALAEGAAERDQANEHPYALVSDLAGAGFGRLRLPREFGGFGVDLPTLFAL
LAEAGQADSNLPQIWRGHFTTTEILLRECDQDARRHWSEKIAAGAVFGNAQSEPSSVVAGIDPTDGCGAI
TTRVRINDRGRRVVSGTKFYSTGSRFADYIRAAVLDEQGRRRFVVIPARHPGVDHVDDWDGIGQRQTGSG
TTILTDVPVEPHGCIGHHLHSVQGLDSFVQIVHLANLTGIARSIVAETVDIVRTRTRTSRHALTQSAAND
PDVLAVIGKLQARRLTAEVLLDRAARRLEAAHAAGDEDSYAEAYTETSTAQVAVIEAVLDAATTAFDAGG
SSAVRTRVHLDRHWRNARTLASHNPVIYKPRVIGDFLVNGNRPVSGYYNGHDTGVDAS*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_4097 - - 100% (409) acyl-CoA dehydrogenase domain-containing protein
M. smegmatis MC2 155 MSMEG_5001 - 1e-61 36.36% (396) pesticide degrading monooxygenase
M. smegmatis MC2 155 MSMEG_4547 - 1e-60 37.25% (400) acyl-CoA dehydrogenase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2528c fadE19 2e-07 20.05% (364) acyl-CoA dehydrogenase
M. gilvum PYR-GCK Mflv_2554 - 3e-10 22.19% (365) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv2500c fadE19 2e-07 20.05% (364) acyl-CoA dehydrogenase
M. leprae Br4923 MLBr_00737 fadE25 8e-06 26.55% (177) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_1422c - 4e-61 36.64% (393) putative acyl-CoA dehydrogenase
M. marinum M MMAR_3847 fadE19 2e-11 22.16% (361) acyl-CoA dehydrogenase FadE19
M. avium 104 MAV_3422 - 1e-60 38.86% (386) acyl-CoA dehydrogenase domain-containing protein
M. thermoresistible (build 8) TH_3721 - 3e-47 40.60% (298) PUTATIVE putative acyl-CoA dehydrogenase family protein
M. ulcerans Agy99 MUL_3778 fadE19 4e-11 21.88% (361) acyl-CoA dehydrogenase FadE19
M. vanbaalenii PYR-1 Mvan_3173 - 2e-32 28.68% (401) acyl-CoA dehydrogenase type 2

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4097|M.smegmatis_MC2_155      ------MTSTQPTELDEALVRIRAVFDALAEGAAE---RDQA--NEHPYA
TH_3721|M.thermoresistible__bu      ------VPYFDEQRFEALAAEFRPVFDRIRAGAVQ---RERD--RELPFE
MAB_1422c|M.abscessus_ATCC_199      ---MTSAPSVLEIRALPGTDTYRNLLAQVAEGARD---RDLD--DENPFD
MAV_3422|M.avium_104                ---MPVAFHRQDT--PAGAAAVQPVLAEIAADYRL---RLADGGTEPPLR
Mb2528c|M.bovis_AF2122/97           --MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYE
Rv2500c|M.tuberculosis_H37Rv        --MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYE
MMAR_3847|M.marinum_M               -----MTTAISAGTLPKEYQDLRDTVADFARSVVAPVSAKHDEEHSFPYE
MUL_3778|M.ulcerans_Agy99           -----MTTAISAGTLPKEYQDLRDTVADFARSVVAPVSAKHDEEHSFPYE
Mflv_2554|M.gilvum_PYR-GCK          -----MSDFLSTGTLPDHYAQLAKTVRDFAQSVVAPVAAKHDEEHSFPYE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
Mvan_3173|M.vanbaalenii_PYR-1       --MATDITDRIPDTLLRTPADALAAAEEVAEAIAAG-SAERERAGAVLTP
                                                                .                     

MSMEG_4097|M.smegmatis_MC2_155      LVSDLAGAGFGRLRLPREFGGFGVDLPTLFALLAEAGQADSNLPQIWRGH
TH_3721|M.thermoresistible__bu      QIGWLKAAGFGAVRLPVSAGGRGATIPELTRLLIELSTADSNITQALRGH
MAB_1422c|M.abscessus_ATCC_199      QVRLLKEAGFGRLRIPTELGGAGLSVRQLFSAIIDVAQADPIVAHIFRTH
MAV_3422|M.avium_104                GLKLVRDHRLGALRLARELGGAGYTAPEFFDYLVALAAADPDLAHILRIH
Mb2528c|M.bovis_AF2122/97           IVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAA
Rv2500c|M.tuberculosis_H37Rv        IVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAA
MMAR_3847|M.marinum_M               VVAKMGEMGLFGLPFPEEYGGMGGDYFALALALEELGKVDQSVAITLEAG
MUL_3778|M.ulcerans_Agy99           VVAKMGEMGLFGLPFPEEYGGMGGDYFALALALEELGKVNQSVAITLEAG
Mflv_2554|M.gilvum_PYR-GCK          VVSGMADMGLFGLPFPEEYGGMGGDYFALCLALEELGKVDQSVAITLEAG
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mvan_3173|M.vanbaalenii_PYR-1       QLRLVAESGLLGISVPTAHGGPGLPASTVVEVLRRLARADGAVGQLLLSH
                                     :  :    :  : ..   ** *         :   . .:          

MSMEG_4097|M.smegmatis_MC2_155      FTTTEILLREC-DQDARRHWSEKIAAGAVFGNAQSEPSSVVAGIDPTDGC
TH_3721|M.thermoresistible__bu      FAFAEDRLVAA-PGPGRDRWWQRFAAGDLAGNAWTEIGDVVLG-------
MAB_1422c|M.abscessus_ATCC_199      FWFVEERLRTL-ADPVSAAWLTKVNEGNLFANAFSEKGSLAVG-------
MAV_3422|M.avium_104                YALVEELQVTP-RRPGSDRWIAVVAEGGLIGGANAEQSQKSVG-------
Mb2528c|M.bovis_AF2122/97           VGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSD-------
Rv2500c|M.tuberculosis_H37Rv        VGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSD-------
MMAR_3847|M.marinum_M               VGLGAMPIYRFGNEEQKSKWLPDLLAGRALAGFGLTEPGAGSD-------
MUL_3778|M.ulcerans_Agy99           VGLGAMPIYRFGNEEQKSKWLPDLLAGRALAGFGLTEPGAGSD-------
Mflv_2554|M.gilvum_PYR-GCK          VSLGAMPVYRFGNESQKQEWLPLLASGKALGAFGLTEAGGGSD-------
MLBr_00737|M.leprae_Br4923          K-LGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSD-------
Mvan_3173|M.vanbaalenii_PYR-1       FVVAQAISGLGHTQPAP-RIYADLLAGAQLGNASAERGTAHAL-------
                                                           .      .                   

MSMEG_4097|M.smegmatis_MC2_155      GAITTRVRINDRGRRVVSGTKFYST--GSRFADYIR-AAVLD-------E
TH_3721|M.thermoresistible__bu      EANTKVAPSGDPGTFVVNGQKFYST--GSIFADWIDLYAQRT-------D
MAB_1422c|M.abscessus_ATCC_199      SLVFNTRLLPVGDAYRLNGEKFYST--GTLFADYLT-VTATT-------D
MAV_3422|M.avium_104                GNHRDTRLVTTPDGLRLRGRKFYST--GAQFSDYLR-ITAQD-------D
Mb2528c|M.bovis_AF2122/97           AGSTRTTARLEGDEWIINGSKQFITNSGTDITSLVTVTAVTGTTGTAADA
Rv2500c|M.tuberculosis_H37Rv        AGSTRTTARLEGDEWIINGSKQFITNSGTDITSLVTVTAVTGTTGTAADA
MMAR_3847|M.marinum_M               AGSTRTTARLDGGEWVVNGSKQFITNSGTDITSLVTITAVTG---SIADG
MUL_3778|M.ulcerans_Agy99           AGSTRTTARLDGGEWVVNGSKQFITNSGTDITSLVTITAVTG---SIADG
Mflv_2554|M.gilvum_PYR-GCK          AGATKTTAKSDGASWVINGTKQFITNSGTDITKLVTVTAVTG----ENNG
MLBr_00737|M.leprae_Br4923          AASMRTRAKADGDDWILNGFKCWITNGGK--STWYTVMAVTD----PDKG
Mvan_3173|M.vanbaalenii_PYR-1       --DRRTTVTRRDGHWVLNGTKYYAT--GTLGATWIAVAARIE-----GRE
                                                    : * * : *  *   :      :           

MSMEG_4097|M.smegmatis_MC2_155      QGRRRFVVIPARHPGVDHVDD-WDGIGQRQTGSGTTILTDVPVEPHGCIG
TH_3721|M.thermoresistible__bu      TGEFVIAAVDAHADGVTHADD-WDGFGQRTTGSGTSTYRDVRVPAENLIP
MAB_1422c|M.abscessus_ATCC_199      RDSVASVIVPGDRDGVRLVDD-WDGFGQRRTGTGTTIFSQVDVAADEILS
MAV_3422|M.avium_104                DGAPTAVVIPVDRAGVEHLDD-WDGIGQRQTGSGTTVFNDVAVADDEVFP
Mb2528c|M.bovis_AF2122/97           KKEISTIIVPSGTPGFTVEPV-YNKVGWNASDTHPLTFADARVPRENLLG
Rv2500c|M.tuberculosis_H37Rv        KKEISTIIVPSGTPGFTVEPV-YNKVGWNASDTHPLTFADARVPRENLLG
MMAR_3847|M.marinum_M               KKEISTIIVPSGTPGFIVEPV-YNKVGWNASDTHPLSFDDARVPEENLLG
MUL_3778|M.ulcerans_Agy99           KKEISTIIVPSGTPGFIVEPV-YNKVGWNASDTHPLSFDDARVPEENLLG
Mflv_2554|M.gilvum_PYR-GCK          KKEISSILVPVPTEGFTAEPA-YNKVGWNASDTHPLSFDDVRVPQENLLG
MLBr_00737|M.leprae_Br4923          ANGISAFIVHKDDEGFSIGPK-EKKLGIKGSPTTELYFDKCRIPGDRIIG
Mvan_3173|M.vanbaalenii_PYR-1       NGDTATAFVRPDQEGVTLDLESWSAFGQRGTASGEVRLNNVVVDDDLLID
                                            :     *.       . .* . : :      .  :  .  : 

MSMEG_4097|M.smegmatis_MC2_155      HHLHSVQGLD------SFVQIVHLANLTGIARSIVAETVDIVRTRTRTSR
TH_3721|M.thermoresistible__bu      FATR-FRYQT------AFYQLFHLATLAGIAHAATAELAQRVRGRTRTFS
MAB_1422c|M.abscessus_ATCC_199      ETPYDAAPVPTT--QYASLQLYILAIVAGVLRAVVDDGEALLRSRQRNFS
MAV_3422|M.avium_104                LG--STIGVNRA--RGALVQLYLHAVAAGILRSLTEDAAALVRGRRRTYT
Mb2528c|M.bovis_AF2122/97           ARGSGYANFLS---ILDEGRIAIAALATGAAQGCVDESVKYANQRQS---
Rv2500c|M.tuberculosis_H37Rv        ARGSGYANFLS---ILDEGRIAIAALATGAAQGCVDESVKYANQRQS---
MMAR_3847|M.marinum_M               IRGKGYANFLS---ILDEGRIAIAALATGVAQGCVDESVKYAKERQS---
MUL_3778|M.ulcerans_Agy99           IRGKGYANFLS---ILDEGRIAIAALATGVAQGCVDESVKYAKERQS---
Mflv_2554|M.gilvum_PYR-GCK          ERGRGYANFLR---ILDEGRIAIAALSVGAAQGCVDESVKYAKERQA---
MLBr_00737|M.leprae_Br4923          EPGTGFKTALA---TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ---
Mvan_3173|M.vanbaalenii_PYR-1       EGPPPDPITADPSVLGAFDQALHAAIDIGIARAALEDGAVFVRTRSRPWK
                                                       :    *   *  :.         . *     

MSMEG_4097|M.smegmatis_MC2_155      HALTQSAA---NDPDVLAVIGKLQARRLTAEVLLDRAARRLEAAHAAGDE
TH_3721|M.thermoresistible__bu      HGNAPRYA---ADPQIQQVVGEVMAAAFAAEAIALRAAEDXXXRRRSS--
MAB_1422c|M.abscessus_ATCC_199      HALTERPV---DDPLLQRTLGELSATAFAAEATVLAAADAIEAATATLRD
MAV_3422|M.avium_104                FASADTPT---ADPQLLQIVGEIDAVAYTAHALVRNAAAELAPALQAARD
Mb2528c|M.bovis_AF2122/97           --FGQPIG---AYQAIGFKIARMEARAHVARTAYYDAAAKMLA-------
Rv2500c|M.tuberculosis_H37Rv        --FGQPIG---AYQAIGFKIARMEARAHVARTAYYDAAAKMLA-------
MMAR_3847|M.marinum_M               --FGQPIG---SYQAISFKIARMEARAHVARTAYYEAAAKMLA-------
MUL_3778|M.ulcerans_Agy99           --FGQPIG---SYQAISFKIARMEARAHVARTAYYEAAAKMLA-------
Mflv_2554|M.gilvum_PYR-GCK          --FGAAIG---TYQAIAFKIARMEARAHTARAAYYDAAALMLS-------
MLBr_00737|M.leprae_Br4923          --FGESIS---TFQSIQFMLADMAMKVEAARLIVYAAAARAER-------
Mvan_3173|M.vanbaalenii_PYR-1       EALDAGIERADQEPHVVRRFGELTARLYALEALLARGTALIDEAYAAPEV
                                                   :   .. :     . .     .:            

MSMEG_4097|M.smegmatis_MC2_155      -----DSYAEAYTETSTAQVAVIEAVLDAATTAFDAGGSSAVRTRVHLDR
TH_3721|M.thermoresistible__bu      --------------------------------------AAPPRRRTRPRS
MAB_1422c|M.abscessus_ATCC_199      GVPDAQLAQEAQVAVAKAKVHIDAVALDAATKLLDLGGASAASRTRNLDR
MAV_3422|M.avium_104                TGIDPELEAAASIAAARVKVAIQEPALRAASRVFDAGGASAVQASALLDR
Mb2528c|M.bovis_AF2122/97           ------GKP-FKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVAR
Rv2500c|M.tuberculosis_H37Rv        ------GKP-FKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVAR
MMAR_3847|M.marinum_M               ------GKP-FKKEAAIAKMISSEAAMDNARDATQVHGGYGFMNEYPVAR
MUL_3778|M.ulcerans_Agy99           ------GKP-FKKEAAIAKMISSEAAMDNARDAAQVHGGYGFMNEYPVAR
Mflv_2554|M.gilvum_PYR-GCK          ------GKP-FKKAASVAKMVASEAAMDNARDATQIFGGYGFMNEYSVAR
MLBr_00737|M.leprae_Br4923          ------GEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVER
Mvan_3173|M.vanbaalenii_PYR-1       TR---DAAAQASLTVAAAKALAQQDAVEIAGAIFELTGTSGTDGAVNLDR
                                                                                      

MSMEG_4097|M.smegmatis_MC2_155      HWRNARTLASHNPVIYKPRVIGDFLVNGNRPVSGYYNGHDTGVDAS
TH_3721|M.thermoresistible__bu      CWDATRSSSVCVPRSRPPRCTSPWAP---RPMSG------------
MAB_1422c|M.abscessus_ATCC_199      HWRNIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF---------
MAV_3422|M.avium_104                HWRNLRTLFSHNPTVYKARVLGDVVVNGAALPDTSFF---------
Mb2528c|M.bovis_AF2122/97           HYRDSKVLEIGEGTTEVQLMLIARSLGLQ-----------------
Rv2500c|M.tuberculosis_H37Rv        HYRDSKVLEIGEGTTEVQLMLIARSLGLQ-----------------
MMAR_3847|M.marinum_M               HYRDSKILEIGEGTTEVQLMLIARSLGLS-----------------
MUL_3778|M.ulcerans_Agy99           HYRDSKILEIGEGTTEVQLMLIARSLGLS-----------------
Mflv_2554|M.gilvum_PYR-GCK          HYRDSKILEIGEGTTEVQLMLIGRELGL------------------
MLBr_00737|M.leprae_Br4923          FMRDAKITQIYEGTNQIQRVVMSRALLR------------------
Mvan_3173|M.vanbaalenii_PYR-1       HWRNVRVHSLHDPARWKYVHLGNHTLHDTRPPRLGLIL--------
                                         :

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_4097	-	-	100% (409)	acyl-CoA dehydrogenase domain-containing protein
M. smegmatis MC2 155	MSMEG_5001	-	1e-61	36.36% (396)	pesticide degrading monooxygenase
M. smegmatis MC2 155	MSMEG_4547	-	1e-60	37.25% (400)	acyl-CoA dehydrogenase family protein