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VLAGFLAMLLLFPVFGGGGMLVMRLSDQVAQDSELVVEGEVPIVSTMVDAAGNPIAWFYQQRRWIVPSER IADTIKLAIVSIEDKRFAEHNGVDLQGTLNGLIGYLRGIDDVRGGSTLEQQYVKNYNLLVKARTQAERRA AVEISPARKLREIRIALALDNALSKGEILTRYLNLVSFGNGAFGVQDAARTYFGVDASQLNWQQAALLAG LVRSTSALNPYTNPDGALSRRNLVLDTMIEYVPDRAAELRAAKATPLGVLPRPDPLPQGCIGARDRAFFC EYALQYLANAGISPDEVARNGYLIRTTLDPVVQDSVKSAVDGIAAPTTRGVASVMSVITPGKTAHRVVAM ADNRTYGLDLDAGETMQPQPFSLVGDGAGSIFKIFTTAAALDMGMGINARLDVPGSFAGRGLGSSDTPGC PKETWCVRNARAYSSPMNVTDALAQSPNTAFAKLISQIGVPRAVDMAVRLGLRSYAQPGSASAYTDNPDE SIADYVKRQNIGSFTLGPLELNALELSNVGATLASGGMWCPPTPIDKVFDRNGKEVGVETVPCEQAVPEG LANTLANALGKDHTGGTATGAASSVGWALPMSGKTGTTESHRSSAFLGFTNQYAAANYIFDDSSSPSGLC SYPLRKCGDGDLYGGTEPARTWYTAMKPIAEHFGPIAMPPTDPRYVEGGPGSQVPSVTGLKLDAARKKLQ DAGFQVAEYPTPVNSSATRGSVVGTTPSGRTIPGSVITINTSTGYVPPPVVVRPPDAPPPPPEGPPPPPN VVLIPGLPPITIPGAPPPPPPPPPPPPPPGTPF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4384 | - | - | 100% (803) | penicillin binding protein transpeptidase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_6201 | - | 0.0 | 72.19% (791) | transglycosylase |
| M. smegmatis MC2 155 | MSMEG_6900 | - | 2e-44 | 25.81% (806) | penicillin-binding protein 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3707 | ponA2 | 0.0 | 69.67% (798) | bifunctional membrane-associated penicillin-binding protein |
| M. gilvum PYR-GCK | Mflv_5209 | - | 0.0 | 75.56% (806) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv3682 | ponA2 | 0.0 | 69.67% (798) | bifunctional membrane-associated penicillin-binding protein |
| M. leprae Br4923 | MLBr_02308 | pon1 | 0.0 | 69.27% (794) | penicillin binding protein (class A) |
| M. abscessus ATCC 19977 | MAB_0408c | - | 0.0 | 65.83% (793) | bifunctional membrane-associated penicillin-binding protein |
| M. marinum M | MMAR_5171 | ponA2 | 0.0 | 69.40% (794) | bifunctional membrane-associated penicillin- binding |
| M. avium 104 | MAV_0446 | - | 0.0 | 69.81% (795) | transglycosylase |
| M. thermoresistible (build 8) | TH_2122 | ponA | 0.0 | 72.05% (762) | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING |
| M. ulcerans Agy99 | MUL_4257 | ponA2 | 0.0 | 69.14% (794) | bifunctional membrane-associated penicillin- binding |
| M. vanbaalenii PYR-1 | Mvan_1068 | - | 0.0 | 76.05% (806) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3707|M.bovis_AF2122/97 MPERL-------PAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRA
Rv3682|M.tuberculosis_H37Rv MPERL-------PAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRA
MMAR_5171|M.marinum_M MSERP-------PAALTLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRA
MUL_4257|M.ulcerans_Agy99 MSERP-------PAALSLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRA
MAV_0446|M.avium_104 ------------------------------MATALLFPVAGGIGLVSNRA
MLBr_02308|M.leprae_Br4923 MSERL-------PAVLAVLKLAGYCLLAGVVTTAMMFPLAGGLGVISNRA
MAB_0408c|M.abscessus_ATCC_199 MPERLSPQ---IPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRA
TH_2122|M.thermoresistible__bu MPEDPPTAPTESTRAATVIKLAWCCLLAAVIAAALMFPVVGGIGLLSNRA
Mflv_5209|M.gilvum_PYR-GCK MRDRRR------AKVIAAGKLAGCVLIAGLLAAALMFPFVGGAGTVVMRV
Mvan_1068|M.vanbaalenii_PYR-1 MSAQGR------AKWGAIARLAGCCLLAGLLAAALMFPFVGGAGTAILRV
MSMEG_4384|M.smegmatis_MC2_155 -------------------------MLAGFLAMLLLFPVFGGGGMLVMRL
: : **. ** * *
Mb3707|M.bovis_AF2122/97 SEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
Rv3682|M.tuberculosis_H37Rv SEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MMAR_5171|M.marinum_M SEVVANGSAQLLQGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MUL_4257|M.ulcerans_Agy99 SEVVANGSAQLLQGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MAV_0446|M.avium_104 SEVVANGSAQLLEGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MLBr_02308|M.leprae_Br4923 SEVVANGSAQLLEGEVPAVSTMVDAKGNTIAWLYSQRRFEVPTDKIANTM
MAB_0408c|M.abscessus_ATCC_199 SDVVANGSTQLLQGEVPAVTTVEDAKGNKIAYLYTQRRFEVSADEIADTM
TH_2122|M.thermoresistible__bu SDVVANGSAQLVEGDVPAVSTMVDAEGNPIAWLYSQRRWEVPSEEIADTM
Mflv_5209|M.gilvum_PYR-GCK SVSATDESADLINGELPRVSTMVDAAGKPIAWLYEQRRWEVPSERIANTM
Mvan_1068|M.vanbaalenii_PYR-1 SNSATEESTQLLEGEVPLVSTMVDAAGNPIAWLYEQRRWVVPGNRIANTM
MSMEG_4384|M.smegmatis_MC2_155 SDQVAQDSELVVEGEVPIVSTMVDAAGNPIAWFYQQRRWIVPSERIADTI
* .:: * :::*::* *:*: ** *: **::* ***: *. :.**:*:
Mb3707|M.bovis_AF2122/97 KLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKN
Rv3682|M.tuberculosis_H37Rv KLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKN
MMAR_5171|M.marinum_M KLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQYIKN
MUL_4257|M.ulcerans_Agy99 KLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQYIKN
MAV_0446|M.avium_104 KLAIVSIEDKRFADHNGVDWKGTLTGLAGYARGDVDTRGGSTIEQQYIKN
MLBr_02308|M.leprae_Br4923 KLAIVSIEDKRFTDHNGVDWPGTLTGLAGYASGDVDTRGGSTIEQQYVKN
MAB_0408c|M.abscessus_ATCC_199 KLALLSIEDKRFTSHNGVDWKGTLGGLAGYASGDEDTRGGSTIEQQYVKN
TH_2122|M.thermoresistible__bu KLAIVAIEDKRFAEHNGVDWQGTLTGLTGYLRGDSDTRGGSTLEQQYVKN
Mflv_5209|M.gilvum_PYR-GCK KLAIVSIEDKRFTEHNGVDWQGTLTGLAGYVRGDKGVRGGSTLEQQYVKN
Mvan_1068|M.vanbaalenii_PYR-1 KLAIISIEDKRFTEHNGVDWQGTLTGLAGYLQGAVTTRGGSTIEQQYVKN
MSMEG_4384|M.smegmatis_MC2_155 KLAIVSIEDKRFAEHNGVDLQGTLNGLIGYLRGIDDVRGGSTLEQQYVKN
***:::******:.*.*** *** ** ** * .*****:****:**
Mb3707|M.bovis_AF2122/97 YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNL
Rv3682|M.tuberculosis_H37Rv YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNL
MMAR_5171|M.marinum_M YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL
MUL_4257|M.ulcerans_Agy99 YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL
MAV_0446|M.avium_104 YQLLVTAKTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL
MLBr_02308|M.leprae_Br4923 YQLLVTAQTDAEKRAAVETTPARKLREIRIALTLDKTFTKPEILTRYLNL
MAB_0408c|M.abscessus_ATCC_199 YQLLVVAKTDAERKAAIETTPARKLREIRMALRLDQTFTKQEILTRYLNL
TH_2122|M.thermoresistible__bu YQLLVVAQTDAEKRAAIETTPARKLREIRMALTLDKTLTKPEILTRYLNL
Mflv_5209|M.gilvum_PYR-GCK FNLLVRAKTDAERRAAVAVTPARKLREIRAALAMDKLLSKTEILTRYLNL
Mvan_1068|M.vanbaalenii_PYR-1 FNLLVKAQTNEDRRAAVEITPARKLREIRAALAMDAALPKAEILTRYLNL
MSMEG_4384|M.smegmatis_MC2_155 YNLLVKARTQAERRAAVEISPARKLREIRIALALDNALSKGEILTRYLNL
::*** *:*: :::**: :********* ** :* :.* *********
Mb3707|M.bovis_AF2122/97 VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPD
Rv3682|M.tuberculosis_H37Rv VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPD
MMAR_5171|M.marinum_M VSFGNNSFGVQDAAQTYFGINASELNWQQSALLAGMVQSTSTLNPYTNPD
MUL_4257|M.ulcerans_Agy99 VSFGNNSFGVQDAAQTYFGINASELNWQQSALLAGMVQSTSTLNPYTNPD
MAV_0446|M.avium_104 VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSALNPYTNPE
MLBr_02308|M.leprae_Br4923 VSFGNNSFGVQDAAQTYFGVNASDLNWQQAALLAGMVQSTSTLNPYTNPE
MAB_0408c|M.abscessus_ATCC_199 VSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGLNPYVNPE
TH_2122|M.thermoresistible__bu VSFGNGAYGIQDAAQTYFGINASELDWHQAALLAGLVQSTTALNPYTNPD
Mflv_5209|M.gilvum_PYR-GCK VAFGNGAFGVQDAARTYFGIDAADLNWAQASLLAGMVRSTSLLDPYTNPD
Mvan_1068|M.vanbaalenii_PYR-1 VSFGNGAFGVQDAARTYFGINAAELNWQQAALLAGMVRSPSSLDPYTYPD
MSMEG_4384|M.smegmatis_MC2_155 VSFGNGAFGVQDAARTYFGVDASQLNWQQAALLAGLVRSTSALNPYTNPD
*:***.::*:****:****::* :*:* *::****:*:*.: *:**. *:
Mb3707|M.bovis_AF2122/97 GALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGD
Rv3682|M.tuberculosis_H37Rv GALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGD
MMAR_5171|M.marinum_M GALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQPNELPRGCIAAGD
MUL_4257|M.ulcerans_Agy99 GALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQPNELPRGCIAAGD
MAV_0446|M.avium_104 GALARRNLVLDTMIENIPQEADALRAAKAAPLGILPQPNELPRGCIAAGD
MLBr_02308|M.leprae_Br4923 GALARRNLVLDTMIENLPQDAEALRAAKTEPLGILPRPNELPRGCIAAGD
MAB_0408c|M.abscessus_ATCC_199 RALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGD
TH_2122|M.thermoresistible__bu GALARRNLVLDTMIDQLPQEAEALRAAKEQPLGILPRPNELPRGCIAAGD
Mflv_5209|M.gilvum_PYR-GCK DALARRNIVLDTMIDNLPEHADELRAAKAQPLGVLPRPAPLPQGCIAAGD
Mvan_1068|M.vanbaalenii_PYR-1 AALERRNVVLNTMIENLPDRADELRAAKARPLGVLPRPDPLPQGCIAAGD
MSMEG_4384|M.smegmatis_MC2_155 GALSRRNLVLDTMIEYVPDRAAELRAAKATPLGVLPRPDPLPQGCIGARD
** ***:**:*** * * *** ***:**:* **:***.* *
Mb3707|M.bovis_AF2122/97 RAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYAS
Rv3682|M.tuberculosis_H37Rv RAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYAS
MMAR_5171|M.marinum_M RAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFAS
MUL_4257|M.ulcerans_Agy99 RAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFAS
MAV_0446|M.avium_104 RAYFCDYVQEYLSRAGISKEQVARGGYLIKTTLDPDVQIPVKAAIDKFAS
MLBr_02308|M.leprae_Br4923 RAFFCDYVQEYLSHAGISKDRLAKGGYLIRTTLDPNVQAPVKAAIDKFAS
MAB_0408c|M.abscessus_ATCC_199 RAFFCDYVLDYLAKSGISKDQVMKGGYLIRTTLDPDVQNSVKQAVSHVAD
TH_2122|M.thermoresistible__bu RAFFCDYVLEYLARAGISKEQVAKGGYLIKTTLDPEVQRAVKSAIDQYAR
Mflv_5209|M.gilvum_PYR-GCK RGFFCEYAMRYLARAGLSMKDVARNGYLIRTTLDPKIQAGVKSAVDHYAE
Mvan_1068|M.vanbaalenii_PYR-1 RAFFCEYALRYLARAGLSREDLARNGYLIRTTLDPKVQDSVKTAINKVAD
MSMEG_4384|M.smegmatis_MC2_155 RAFFCEYALQYLANAGISPDEVARNGYLIRTTLDPVVQDSVKSAVDGIAA
*.:**:*. **:.:*:* . : .****:***** :* ** *:. *
Mb3707|M.bovis_AF2122/97 PNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVG
Rv3682|M.tuberculosis_H37Rv PNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVG
MMAR_5171|M.marinum_M PTLPGISSVMSVIKPGKESHQVLAMASNRKYGLDINAGETMRPQPFSLVG
MUL_4257|M.ulcerans_Agy99 PTLPGISSVMSVIKPGKESHQVLAMASNRAYGLDINAGETMRPQPFSLVG
MAV_0446|M.avium_104 PTLPGISSVMSVIQPGKTSHKVMAMASNRTYGLDVDAGQTMRPQPFSLVG
MLBr_02308|M.leprae_Br4923 PNLAGISSVMSVITPGKDAHRVIAMGSNRRYGLDTEAGETMRPQTFSLVG
MAB_0408c|M.abscessus_ATCC_199 PGLNGIANVMSVIKPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVG
TH_2122|M.thermoresistible__bu PDANGVASVMSVIRPGKESHPVLAMASSRHYGLNSEAGETMQPQPFSLVG
Mflv_5209|M.gilvum_PYR-GCK PTTPGVASVMSVILPGKDAHRVVAMADNRSYGLDLNAGQTVQPQPFTLAG
Mvan_1068|M.vanbaalenii_PYR-1 PTAVGVASVMSVIRPGRDAHRIVAMADSRTYGLDRDAGQTVQPQPFSLVG
MSMEG_4384|M.smegmatis_MC2_155 PTTRGVASVMSVITPGKTAHRVVAMADNRTYGLDLDAGETMQPQPFSLVG
* *::.***** **: :* ::**...* ***: :* :*::**.*:*.*
Mb3707|M.bovis_AF2122/97 DGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSG-GAKGCPKET
Rv3682|M.tuberculosis_H37Rv DGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSG-GAKGCPKET
MMAR_5171|M.marinum_M DGAGSIFKIFTTAAALDMGMGINAQLDVPGRFQGKGLGSG-GAKGCPKDT
MUL_4257|M.ulcerans_Agy99 DGAGSIFKIFTTAAALDMGMGISAQLDVPGRFQGKGLGSG-GAKGCPKDT
MAV_0446|M.avium_104 DGAGSVFKIFTTAAALDMGMGINATLEVPGRFQAKGMGSG-GAKGCPKDT
MLBr_02308|M.leprae_Br4923 DGAGSVFKIFTTAAALDMGMGINAKLEVPSRFQAKGMGSG-GAKGCPKET
MAB_0408c|M.abscessus_ATCC_199 DGAGSIFKIFTVAAAMDMGMGINTVLDVPPTFAAKGLGSSDGSKGCPKDN
TH_2122|M.thermoresistible__bu HGAGSVFKIFTTAAAMEMGMGINTQLEAPAFFQAKGLGSS-DTPGCPAAT
Mflv_5209|M.gilvum_PYR-GCK DGAGSIFKIFTTAAALEMGLGINATLDVPQTFRATGLGDS-TEPGCPPKT
Mvan_1068|M.vanbaalenii_PYR-1 DGAGSIFKIFTTAAALEMGLGINAKLDVPQTFRGTGLGDS-SEPGCPPKT
MSMEG_4384|M.smegmatis_MC2_155 DGAGSIFKIFTTAAALDMGMGINARLDVPGSFAGRGLGSS-DTPGCPKET
.****:*****.***::**:**.: *:.* * . *:*.. *** .
Mb3707|M.bovis_AF2122/97 WCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRS
Rv3682|M.tuberculosis_H37Rv WCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRS
MMAR_5171|M.marinum_M WCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGLRS
MUL_4257|M.ulcerans_Agy99 WCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGLRS
MAV_0446|M.avium_104 WCVVNAGNYKGSMNVTEALATSPNTAFAKLIQQVGVTRTVDMAIKLGLRS
MLBr_02308|M.leprae_Br4923 WCVINAGNYRGSMNVTDALATSPNTAFAKLIQQVGVARTVDMAIKLGLRS
MAB_0408c|M.abscessus_ATCC_199 WCVKNVGNYRSPMSVTDALATSPNTAFAKLIQSIGVSKAVDMAVKLGMRS
TH_2122|M.thermoresistible__bu WCVRNAGSYRGSMNVTDALATSPNTAFAKLISQIGVPRTVDMAVRLGLRS
Mflv_5209|M.gilvum_PYR-GCK WCVKNVSGFSGQMNVTDALAKSPNTAFAKLISQIGVPRAVDMAVRLGLRS
Mvan_1068|M.vanbaalenii_PYR-1 WCVKNVSGYGGQMTVTDALAKSPNTAFAKLIAQIGVPRAMDMAVRLGLRS
MSMEG_4384|M.smegmatis_MC2_155 WCVRNARAYSSPMNVTDALAQSPNTAFAKLISQIGVPRAVDMAVRLGLRS
*** *. : . *.**:*** ********** .:** :::***::**:**
Mb3707|M.bovis_AF2122/97 YANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLA
Rv3682|M.tuberculosis_H37Rv YANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLA
MMAR_5171|M.marinum_M YANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
MUL_4257|M.ulcerans_Agy99 YANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
MAV_0446|M.avium_104 YADPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
MLBr_02308|M.leprae_Br4923 YTTPGTARDYNPDSNESLADFVKRQNIGSFTLGPIKVNALELSNVAATLA
MAB_0408c|M.abscessus_ATCC_199 YAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELSNVAATLA
TH_2122|M.thermoresistible__bu YAQPGTARDYDPNSDESIADWVKRQNIGSFTLGPIEVNALELSNVAATLA
Mflv_5209|M.gilvum_PYR-GCK YAEPGSARVYDPETDESIADFVKRQNIGSFTLGPFELNALELTNVAATLA
Mvan_1068|M.vanbaalenii_PYR-1 YAEPGTARAYDPETDESIADFVKRQNLGSFTLGPLELNALELSNVAATLA
MSMEG_4384|M.smegmatis_MC2_155 YAQPGSASAYTDNPDESIADYVKRQNIGSFTLGPLELNALELSNVGATLA
*: **:* * : :**:*:::*: *:*******:::*.***:**.****
Mb3707|M.bovis_AF2122/97 SGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAV
Rv3682|M.tuberculosis_H37Rv SGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAV
MMAR_5171|M.marinum_M SGGVWCPPNPVDKLIDRNGNEVAVTTETCDQVVPEGLANTLANAMSKDAV
MUL_4257|M.ulcerans_Agy99 SGGVWCPPNPVDKLIDRNGNEVAVTTETCDQVVPEGLANTLANAMSKDAV
MAV_0446|M.avium_104 SGGTWCPPNPIDKLIDRKGNEVAVTTETCDQVVPEGLANTMANAMSKDAV
MLBr_02308|M.leprae_Br4923 SGGMWCPPNPIDKLFDRNGNEVAVTVETCDRVVPEGLANTLANAMSKDTK
MAB_0408c|M.abscessus_ATCC_199 SGGKWCPPNPIDKVFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQ
TH_2122|M.thermoresistible__bu SGGVWCPPNPIDKVYDRHGNEVSVTTETCEQVVPEGLANTLANAMSEDDR
Mflv_5209|M.gilvum_PYR-GCK SGGMWCLPSPIDKVFDRHGNEVPLQTPPCEQAVPEGLANAMANALGKDHT
Mvan_1068|M.vanbaalenii_PYR-1 SGGMWCPPSPIDTVFDRHGGEVALEEAPCEQVVPEGLANTMANALGKDHI
MSMEG_4384|M.smegmatis_MC2_155 SGGMWCPPTPIDKVFDRNGKEVGVETVPCEQAVPEGLANTLANALGKDHT
*** ** *.*:* : **:* ** .*::.** ****::***:.:*
Mb3707|M.bovis_AF2122/97 GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
Rv3682|M.tuberculosis_H37Rv GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
MMAR_5171|M.marinum_M GGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
MUL_4257|M.ulcerans_Agy99 GGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
MAV_0446|M.avium_104 GGGTAAGSAGAAGWDLPMSGKTGTTEAHRSSGFVGFTNHYAAANYIYDDS
MLBr_02308|M.leprae_Br4923 GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSSGFVGFTNHYAAANYIYDDS
MAB_0408c|M.abscessus_ATCC_199 PGGTAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGASYIYDDS
TH_2122|M.thermoresistible__bu GAGTAAGAAASVGWDLPMSGKTGTTESNRSSAFLGFTNQLAAANYIYDDS
Mflv_5209|M.gilvum_PYR-GCK G-GTATGAAGSVGWDLPMSGKTGTTESHRSSAFLGFTNRYAAANYIFDDS
Mvan_1068|M.vanbaalenii_PYR-1 S-GTATSAAGSVGWDLPMAGKTGTTESHRSSAFLGFTNQYAAANYIFDDS
MSMEG_4384|M.smegmatis_MC2_155 G-GTATGAASSVGWALPMSGKTGTTESHRSSAFLGFTNQYAAANYIFDDS
***:.:*.:.** **::.******::**:.*:*:**. *.*.**:***
Mb3707|M.bovis_AF2122/97 SSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDP
Rv3682|M.tuberculosis_H37Rv SSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDP
MMAR_5171|M.marinum_M TNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDP
MUL_4257|M.ulcerans_Agy99 TNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDP
MAV_0446|M.avium_104 PNPTDLCSAPLRHCGEGDLYGGNEPARTWFTAMKPIATNFGPVQLPPTDP
MLBr_02308|M.leprae_Br4923 TSPTNLCSGPLRHCSNGDLYGGNEPARTWFTAMKPIATKFGEVRLPPTDP
MAB_0408c|M.abscessus_ATCC_199 TTPGDLCSFPLRKCGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEP
TH_2122|M.thermoresistible__bu NSPGELCSFPLRRCGSGDLFGGNEPARTWFAAMKPIAEKFGPVALPPTDP
Mflv_5209|M.gilvum_PYR-GCK PSPSGLCSYPLRKCGSGDLYGGTEPALTWYRAMKPIAEDFGPVSLPPTEP
Mvan_1068|M.vanbaalenii_PYR-1 PTPSGLCTSPLRRCRDGNLYGGTEPARTWYLAMKPIAEDFGPVAMPPTDP
MSMEG_4384|M.smegmatis_MC2_155 SSPSGLCSYPLRKCGDGDLYGGTEPARTWYTAMKPIAEHFGPIAMPPTDP
.* **: ***:* .*:*:**.**: :*: *:**** .:* :***:*
Mb3707|M.bovis_AF2122/97 RYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVV
Rv3682|M.tuberculosis_H37Rv RYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVV
MMAR_5171|M.marinum_M RYVDGAPGSRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEVV
MUL_4257|M.ulcerans_Agy99 RYVDGAPGSRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEAV
MAV_0446|M.avium_104 RYVDGAPGSRVPSVAGLDIDAARQRIKEAGFQVADQNNFVNSSAKQGEVV
MLBr_02308|M.leprae_Br4923 RYVDGSPGSQVPSVTGLDLDAARQRLKGAGFQVADQPTLINSTAKLGAVV
MAB_0408c|M.abscessus_ATCC_199 RYVEGGPGSKVPSINGLREPEARDVLKKAGFRVADQASSVNSTAPFNEVV
TH_2122|M.thermoresistible__bu RYVDGGPGSRVPSVSGLSEEAARQRLRDAGFQVADGVATVNSSARRGTVV
Mflv_5209|M.gilvum_PYR-GCK RYVDGGPNSEVPSVTGMKFDAARNKLTENGFQVSPEPTAINSGAARGTVV
Mvan_1068|M.vanbaalenii_PYR-1 RYVDGGPGSEVPRVIGLKIDAARKKLEDAGFQVAAEPTAVNSSSAKGVIV
MSMEG_4384|M.smegmatis_MC2_155 RYVEGGPGSQVPSVTGLKLDAARKKLQDAGFQVAEYPTPVNSSATRGSVV
***:*.*.*.** : *: **. : **:*: :** : . *
Mb3707|M.bovis_AF2122/97 GTSPSGQTIPGSIVTIQISN-----GIPPAPPPPPLPE-----DGGPPPP
Rv3682|M.tuberculosis_H37Rv GTSPSGQTIPGSIVTIQISN-----GIPPAPPPPPLPE-----DGGPPPP
MMAR_5171|M.marinum_M GTSPSGQTIPGSIITIQISN-----GIPPAPPPPP--------EGEPPPP
MUL_4257|M.ulcerans_Agy99 GTSPSGQTIPGSIITIQISN-----GIPPAPPPPP--------EGEPPPP
MAV_0446|M.avium_104 GTTPSGATIPGSIITIQVSN-----GIPPAPPPPP---------EGAPPP
MLBr_02308|M.leprae_Br4923 GTTPSGQTIPGSIITIQTSS-----GIPPAPPPPP--------EGGPPMP
MAB_0408c|M.abscessus_ATCC_199 GTSPSGTTIPGSVITILMSN-----GIPPAPPPLVIPG-----IPGAPPG
TH_2122|M.thermoresistible__bu GTNPSGQTIPXXYPTQFLRADLDALGVIPADKLLEVPDGTRILIAGAVTH
Mflv_5209|M.gilvum_PYR-GCK GTSPRGKTIPGSIVTILVSN-----GIPPVVYRPPPPP-----SAPPPPP
Mvan_1068|M.vanbaalenii_PYR-1 GTTPSGKTIPGSIITINTSN-----GIAPAPVYQPPPP-----GAPPPPP
MSMEG_4384|M.smegmatis_MC2_155 GTTPSGRTIPGSVITINTST-----GYVPPPVVVRPP------DAPPPPP
**.* * *** * * * .
Mb3707|M.bovis_AF2122/97 --------VGSQVVEIPGLPPIT--IPLLAPPPPAPPP------------
Rv3682|M.tuberculosis_H37Rv --------VGSQVVEIPGLPPIT--IPLLAPPPPAPPP------------
MMAR_5171|M.marinum_M --------VGSQVVEIPGLPPIT--IPLLAPPPP----------------
MUL_4257|M.ulcerans_Agy99 --------VGSQVVEIPGLPPIT--IPLLAPPPP----------------
MAV_0446|M.avium_104 --------VGSQVVEIPGLPPIT--IPLLAPPPPAPGQPPP---------
MLBr_02308|M.leprae_Br4923 P------SVGSQVIEIPGLPPIT--IPLLAPP------------------
MAB_0408c|M.abscessus_ATCC_199 -------EMTTTIVNIPGLPPIT--VPVLAPPP-----------------
TH_2122|M.thermoresistible__bu RQ----RPATAQGVTFLNLEDETGMVNVLCSPGVWARHRRLAQTAPALLV
Mflv_5209|M.gilvum_PYR-GCK PGDAPPPPPPPNVIEIPGLPPIV--LPWPAPPPP------PPAPPPPPPA
Mvan_1068|M.vanbaalenii_PYR-1 PG--APPPPPPNVIQIPGLPPIV--LPWPAPPPPPLPLPPPPPPQPPPPA
MSMEG_4384|M.smegmatis_MC2_155 EG----PPPPPNVVLIPGLPPIT--IPGAPPPPP------PPPPPPPPPG
. : : .* . : .*
Mb3707|M.bovis_AF2122/97 ---------------------------------
Rv3682|M.tuberculosis_H37Rv ---------------------------------
MMAR_5171|M.marinum_M ---------------------------------
MUL_4257|M.ulcerans_Agy99 ---------------------------------
MAV_0446|M.avium_104 ---------------------------------
MLBr_02308|M.leprae_Br4923 ---------------------------------
MAB_0408c|M.abscessus_ATCC_199 ---------------------------------
TH_2122|M.thermoresistible__bu RGIVQNATGAVTVVADRMRRLELRVGSRSRDFR
Mflv_5209|M.gilvum_PYR-GCK ---------------------------------
Mvan_1068|M.vanbaalenii_PYR-1 ---------------------------------
MSMEG_4384|M.smegmatis_MC2_155 TPF------------------------------