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PPDDRLTAVLPPVRDGDIAPPIDVVRAALEGSPPPKPPPPPPPGRGGGGPSGPGGPSGPGRQFRINWKWV RRGSAIAVAVMVLLPLITFGMAYMIVDVPEPGDIRTPQVSTILASDGSEIARIVPPEGNRVDVKIDQIPV HVRDAVMAAEDRDFYSNPGFSWTGFLRAIKNNLFGGGGLQGGSTITQQYVKNALVGDERSGIGGLIRKAK ELVISTKMSGEWSKDAVLQAYLNIIYFGRGAYGISAASKAYFDKPVEQLDVAEGALLAALIQRPSTLDPA VDPEGAADRWNWVLDGMVDIGALSQADRDAQVFPPTVPPDYAFQQNQTTGPNGLIERQVTNELLDLFDIN EQTLNTEGLQITTTIDPKAQEAAVDAVDKYLEGQDPDMRAAVVSIDPRTGGIKAYYGGSDANGFDFAQAG LPTGSSFKVFALVAALQQGIGLGYQIDSGPLEVNGIKIGNVEGEGCGTCSIAEALKRSLNTSYYRLMLKL ENGPADVAEAAHDAGVAESFPGVEHTLSEDGKGGPPNNGVVLGQYQSRVLDMASAYATLAASGVYHKPHF VEKVVNSSGQVLFDASKEDNGEERIDKAVADNVTSAMQPIAGWSRGHNLAGGRPSAAKTGTVQLGDTGDN RDAWMVGYTPSLSTAVWVGTTEGVKPLVNKWGSPIYGSGLPSDIWKATMDGALEGTDVESFPKPTEIGGY AGVPQAPAAPPPSAGPPTDPGQPSVTVIQPTIEVAPGITIPIGPPTTVPVGPPPGAPGAPVGPGAPEVPV APGAPGVPGAPPPP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6900 | - | - | 100% (785) | penicillin-binding protein 1 |
M. smegmatis MC2 155 | MSMEG_6201 | - | 4e-50 | 26.30% (768) | transglycosylase |
M. smegmatis MC2 155 | MSMEG_4384 | - | 2e-44 | 25.81% (806) | penicillin binding protein transpeptidase domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0051 | ponA1 | 0.0 | 78.56% (681) | bifunctional penicillin-binding protein 1A/1B |
M. gilvum PYR-GCK | Mflv_0871 | - | 0.0 | 77.28% (810) | glycosyl transferase family protein |
M. tuberculosis H37Rv | Rv0050 | ponA1 | 0.0 | 78.85% (681) | bifunctional penicillin-binding protein 1A/1B |
M. leprae Br4923 | MLBr_02688 | ponA | 0.0 | 72.81% (695) | penicillin-bonding protein |
M. abscessus ATCC 19977 | MAB_4901c | - | 0.0 | 69.19% (779) | penicillin-binding protein |
M. marinum M | MMAR_0069 | ponA1 | 0.0 | 78.22% (698) | bifunctional penicillin-binding protein 1A/1B PonA1 |
M. avium 104 | MAV_0071 | - | 0.0 | 72.03% (833) | transglycosylase |
M. thermoresistible (build 8) | TH_3201 | - | 0.0 | 79.02% (691) | PUTATIVE glycosyl transferase, family 51 |
M. ulcerans Agy99 | MUL_0068 | ponA1 | 0.0 | 77.91% (688) | bifunctional penicillin-binding protein 1A/1B PonA1 |
M. vanbaalenii PYR-1 | Mvan_6036 | - | 0.0 | 80.67% (802) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0871|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6036|M.vanbaalenii_PYR-1 ---------------------------MGARNPQHRKDDPVRRPGEGGVR MSMEG_6900|M.smegmatis_MC2_155 -------------------------------------------------- TH_3201|M.thermoresistible__bu --------------------------------------------MRLSTL MMAR_0069|M.marinum_M -------------------------------------------------- MUL_0068|M.ulcerans_Agy99 -------------------------------------------------- MAV_0071|M.avium_104 MSSNNEGRHSQSSGDQRGPAAEQGAGERRETARPDADPQRRNGPSTSSRR Mb0051|M.bovis_AF2122/97 -------------------------------------------------- Rv0050|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02688|M.leprae_Br4923 -------------------------------------------------- MAB_4901c|M.abscessus_ATCC_199 ---------------------------------MVGEENSVAPNSGPDSP Mflv_0871|M.gilvum_PYR-GCK --MPPDDRHTAVLPPFRDGPPPPTRDPIDAVKSALDSRDRR--------- Mvan_6036|M.vanbaalenii_PYR-1 RAPAPDDRHTTVIPPVRDGAPPPLRDPIDAVKRALDGGAR---------- MSMEG_6900|M.smegmatis_MC2_155 --MPPDDRLTAVLPPVRDGDIAP---PIDVVRAALE-------------- TH_3201|M.thermoresistible__bu ATTAAAVALTGTVGGLATGPAARSRWFARLKKPGFQPPAQ---------- MMAR_0069|M.marinum_M -------------------------------------------------- MUL_0068|M.ulcerans_Agy99 -------------------------------------------------- MAV_0071|M.avium_104 RQAPPDDRLTTILPPVDDDRAPRRSDPIEEVKAALAGPPSTPLRRDALDE Mb0051|M.bovis_AF2122/97 -------------------------------------------------- Rv0050|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02688|M.leprae_Br4923 -------------------------------------------------- MAB_4901c|M.abscessus_ATCC_199 RTPSTDDRPTSILDPIEDLPLYRRDDDAVAAARAALERDED--------- Mflv_0871|M.gilvum_PYR-GCK ----------RRDGDRRREGDQRRGS-GPPPPPPGPPRHGGGGPTGGDGP Mvan_6036|M.vanbaalenii_PYR-1 -------------GERKNFGPPKQPPPSQPPPPPGRP-PGGGGPPGGGGP MSMEG_6900|M.smegmatis_MC2_155 ------------------------GSPPPKPPPPPPPGRGGGGPSGPGGP TH_3201|M.thermoresistible__bu -------------------AFPIVWPILYTDIAGVSAATIDRLXXXPGEP MMAR_0069|M.marinum_M -------------------------------------------------- MUL_0068|M.ulcerans_Agy99 -------------------------------------------------- MAV_0071|M.avium_104 VKAALDSRGPASGRQQRAGLGGRPPVGPPPPPPRRGWSGGPGGPGGRGSG Mb0051|M.bovis_AF2122/97 -------------------------------------------------- Rv0050|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02688|M.leprae_Br4923 ------------------------------------------MPGSRLNR MAB_4901c|M.abscessus_ATCC_199 -----------------------GGRGHEPPPPPGTP-----GRPGGSSR Mflv_0871|M.gilvum_PYR-GCK SGPPRSLREQINWTWVRRGSLIAAVVLIVLPLLTFGMAYMIVDVPKPGDI Mvan_6036|M.vanbaalenii_PYR-1 AGPRRSLREQINWKWVRRGSIIAAAVLILLPLLTFGMAYMIVDVPKPGDI MSMEG_6900|M.smegmatis_MC2_155 SGPGRQFR--INWKWVRRGSAIAVAVMVLLPLITFGMAYMIVDVPEPGDI TH_3201|M.thermoresistible__bu PEEPANWFDRINWRWVRRGLFAGAVALLVLPIITFVMAYLIVDVPRPGDI MMAR_0069|M.marinum_M ---------------MRRSAYLAAAVVILLPIVTFTMAYFIVDVPRPGDI MUL_0068|M.ulcerans_Agy99 -------------------------MVILLPIVTFTVAYFIVDVPRPGDI MAV_0071|M.avium_104 PWRDWSWTQQINWLWVRRAAYLCAAVLVLLPIVTFAMAYFIVDIPKPGDL Mb0051|M.bovis_AF2122/97 -------------------------MVILLLMVTFTMAYLIVDVPKPGDI Rv0050|M.tuberculosis_H37Rv -------------------------MVILLPMVTFTMAYLIVDVPKPGDI MLBr_02688|M.leprae_Br4923 TWLLHLN-RQVNWRWVRYSLYLAVVVLLLLPIVTFTMTYFMVKVPRPGDI MAB_4901c|M.abscessus_ATCC_199 PPQRRRKRKSNGWKIFRNVMIALVLLAIVIPLATFALAYSVVDIPKPGDI ::: : ** ::* :*.:*.***: Mflv_0871|M.gilvum_PYR-GCK RTAQVSTILASDGS-EIAKIVPPEGNRIDVNIDQIPVHVRDAVMAAEDRD Mvan_6036|M.vanbaalenii_PYR-1 RTAQVSTILASDGS-EIAKIVPPEGNRVDVDIDQIPVHVRDAVMAAEDRD MSMEG_6900|M.smegmatis_MC2_155 RTPQVSTILASDGS-EIARIVPPEGNRVDVKIDQIPVHVRDAVMAAEDRD TH_3201|M.thermoresistible__bu RTNQVSTILASDGS-ELARIVPPEGNRIDVNINQIPVHVRDAVMAAEDRD MMAR_0069|M.marinum_M RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPEHVRAAVIAAEDRG MUL_0068|M.ulcerans_Agy99 RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPEHVRAAVIAAEDRG MAV_0071|M.avium_104 RTNQVSTILASDGS-EIAKIIPPEGNRVDVNLNQVPVHVRQAVIAAEDRN Mb0051|M.bovis_AF2122/97 RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPMHVRQAVIAAEDRN Rv0050|M.tuberculosis_H37Rv RTNQVSTILASDGS-EIAKIVPPEGNRVDVNLSQVPMHVRQAVIAAEDRN MLBr_02688|M.leprae_Br4923 RTNQVSTILANNGL-EIAKIVPPEGNRVDVNLSQVPVHVRQAVIAAEDRN MAB_4901c|M.abscessus_ATCC_199 RTSQVSTILASDGTTELAKVVPPEGNRVDIKIDQVPQHVRAAVMAAEDRD ** *******.:* *:*:::******:*:.:.*:* *** **:*****. Mflv_0871|M.gilvum_PYR-GCK FYSNPGFSFTGFLRAFKNNIFGG-DLQGGSTITQQYVKNALVGDARSGVG Mvan_6036|M.vanbaalenii_PYR-1 FYSNPGFSFTGFLRAAKNNIFGG-DLQGGSTITQQYVKNALVGDARSGVG MSMEG_6900|M.smegmatis_MC2_155 FYSNPGFSWTGFLRAIKNNLFGGGGLQGGSTITQQYVKNALVGDERSGIG TH_3201|M.thermoresistible__bu FYSNPGFSFTGFARAIGNNIFGG-DVQGGSTITQQYVKNALVGSERVGVR MMAR_0069|M.marinum_M FYSNPGFSFSGFARAIKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS MUL_0068|M.ulcerans_Agy99 FYSNPGFSFSGFARAIKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS MAV_0071|M.avium_104 FYSNPGFDFSGFARAVNNNLFGNGDLQGGSTITQQYVKNALVGSAQHGVS Mb0051|M.bovis_AF2122/97 FYSNPGFSFTGFARAVKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS Rv0050|M.tuberculosis_H37Rv FYSNPGFSFTGFARAVKNNLFG-GDLQGGSTITQQYVKNALVGSAQHGWS MLBr_02688|M.leprae_Br4923 FYSNPGFDFRASVRAVQNNLFGSGDLQGGSTITQQYVKNALVGSAQHGFD MAB_4901c|M.abscessus_ATCC_199 FYGNPGFSFSGLLRAVKNNMFG-GDTQGGSTITQQYVKNAMVGSQRAGLG **.****.: . ** **:** . **************:**. : * Mflv_0871|M.gilvum_PYR-GCK GVIRKAKELVISTKMSSEWSKDQVLQSYLNIIYFGRGAYGVAAAAKAYFG Mvan_6036|M.vanbaalenii_PYR-1 GLIRKAKELVISTKMSSEWSKDQVLQSYLNIIYFGRGAYGVAAAAQAYFG MSMEG_6900|M.smegmatis_MC2_155 GLIRKAKELVISTKMSGEWSKDAVLQAYLNIIYFGRGAYGISAASKAYFD TH_3201|M.thermoresistible__bu GLIRKAKELVISTKMSRQWSKDQVMQSYLNIIYFGRGAYGVAAASRAYFD MMAR_0069|M.marinum_M GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD MUL_0068|M.ulcerans_Agy99 GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD MAV_0071|M.avium_104 GLMRKAKELVIATKMSGEWSKDEVLQSYLNIIYFGRGAYGISAAAKAYFD Mb0051|M.bovis_AF2122/97 GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD Rv0050|M.tuberculosis_H37Rv GLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRGAYGISAASKAYFD MLBr_02688|M.leprae_Br4923 GLMRKTKELVIAIKMSDAWSKDDVLQSYLNIIYFGRGAYGISAAAKAYFD MAB_4901c|M.abscessus_ATCC_199 GLTRKAKEIVISTKMSQSWSKDQVMEAYLNIIYFGRGAYGISAASKAYFD *: **:**:**: *** **** *:::*************::**::***. Mflv_0871|M.gilvum_PYR-GCK KPIEEVTVSEGALLAALIQRPSVLDPAVDPDASAVRWSWVLDGMVEIGAL Mvan_6036|M.vanbaalenii_PYR-1 KPVEQLNVSEGALLAALIQRPSVLDPAVDPDASAVRWSWVLDGMVEIGAL MSMEG_6900|M.smegmatis_MC2_155 KPVEQLDVAEGALLAALIQRPSTLDPAVDPEGAADRWNWVLDGMVDIGAL TH_3201|M.thermoresistible__bu KPVEELNVAEGALLAALIQRPSTLDPAADPQGAETRWNWVLDGMVEIGAL MMAR_0069|M.marinum_M KPVEQLTVSEGALLAALIRRPSTLDPAVDPDGALARWNWVLDGMVDTKAL MUL_0068|M.ulcerans_Agy99 KPVEQLTVSEGALLAALIRRPSTLDPAVDPDGALARWNWVLDGMVDTKAL MAV_0071|M.avium_104 KPVEQLTVSEGALLAALIRRPSTLDPAVDPKGALARWNWVLDGMVETKAL Mb0051|M.bovis_AF2122/97 KPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARWNWVLDGMVETKAL Rv0050|M.tuberculosis_H37Rv KPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARWNWVLDGMVETKAL MLBr_02688|M.leprae_Br4923 KPVEQLTCSEGALLAALIRRPSVLDPAINLKGVTARWNWVLDGMVDINAL MAB_4901c|M.abscessus_ATCC_199 KPVEQLTVSEGALLAALIQRPSRLDPAVDLPESTNRWNWVLDGMVTIGAL **:*:: :*********:*** **** : **.******* ** Mflv_0871|M.gilvum_PYR-GCK SEQDRAAQIFPPTIPPDQASTQNQTTGPNGLIERQVVSELMEIFDINEQA Mvan_6036|M.vanbaalenii_PYR-1 SPEDRAGQVFPPTIPPDQAFTQNQTTGPNGLIERQVVNELMEIFDINEQT MSMEG_6900|M.smegmatis_MC2_155 SQADRDAQVFPPTVPPDYAFQQNQTTGPNGLIERQVTNELLDLFDINEQT TH_3201|M.thermoresistible__bu SPQERAAQVFPPTVPPELARSQNQTTGPNGLIERQVTRELLELFNISEQA MMAR_0069|M.marinum_M SAKDRAEQVFPRTVPPDQARAANQTTGPNGLIERQVTKELLELFNIDEQT MUL_0068|M.ulcerans_Agy99 SAKDRAEQAFPRTVPPDQARAANQTTGPNGLIERQVTKELLELFNIDEQT MAV_0071|M.avium_104 PAKDRAAQVFPQTVPPDQARAQNQTTGPNGLIERQVTKELMELFNIDERT Mb0051|M.bovis_AF2122/97 SPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQT Rv0050|M.tuberculosis_H37Rv SPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQT MLBr_02688|M.leprae_Br4923 SPNDRSVQLFPATVPPDQARAQNQTTGPNGLIERQVVKELFELFNIDRQT MAB_4901c|M.abscessus_ATCC_199 SAQDRAGQVYPATVPPEQAAAQNATTGPNGLIKRQVMAELTDLFNIDEQT . :* * :* *:**: * * *.******:*** ** ::*:*..:: Mflv_0871|M.gilvum_PYR-GCK LNTEGLQITTTIDPKAQSAAQDAVEDYLDGQDPDMRSAVVSIDPKTGGIK Mvan_6036|M.vanbaalenii_PYR-1 LNTEGLQITTTIDPQMQAAAVDAVEEYMDGQDPDMRTAVVSIDPRTGGVR MSMEG_6900|M.smegmatis_MC2_155 LNTEGLQITTTIDPKAQEAAVDAVDKYLEGQDPDMRAAVVSIDPRTGGIK TH_3201|M.thermoresistible__bu LNTEGLQITTTIDPQAQQAAVDAVETYLEGQDPDMRAAVVSIDPRTGAVK MMAR_0069|M.marinum_M LNTQGLQVTTTIDAQAQQAAEKAVAKYLDGQDPEMRAAVVSIDPHNGAVR MUL_0068|M.ulcerans_Agy99 LNTQGLQVTTTIDAQAQQAAEKAVAKYLDGQDPEMRAAVVSIDPHNGAVR MAV_0071|M.avium_104 LNTQGLQVTTTIDPKAQQAAEKAVSKYLDGQDPDMRAAVVSVDPHDGAIR Mb0051|M.bovis_AF2122/97 LNTQGLVVTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVR Rv0050|M.tuberculosis_H37Rv LNTQGLVVTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVR MLBr_02688|M.leprae_Br4923 LNTQGLQVITTIDPQAQRIVEKAVSKYLDGQDPDMRAAIVSIDPHNGAIR MAB_4901c|M.abscessus_ATCC_199 LNTEGLQITTTIDTKAQQAAENAVNTTLQSENPDLRTAVVSIDPRTGAVK ***:** : ****.: * . .** ::.::*::*:*:**:**: *.:: Mflv_0871|M.gilvum_PYR-GCK AYYGGSDAAGFDFAQAGLPTGSSFKVFALIAALEQGMGLGYQVDSSPLEV Mvan_6036|M.vanbaalenii_PYR-1 AYYGGSDANGFDFAQAGLPTGSSFKVFALVAALQQGMGLGYQVDSSPVEV MSMEG_6900|M.smegmatis_MC2_155 AYYGGSDANGFDFAQAGLPTGSSFKVFALVAALQQGIGLGYQIDSGPLEV TH_3201|M.thermoresistible__bu AYYGGSDANGYDFAQAAVPTGSSFKVFALVAALEQGMGLGYQVDSSPLTV MMAR_0069|M.marinum_M AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYDVDSSPLTV MUL_0068|M.ulcerans_Agy99 AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYDVDSSPLTV MAV_0071|M.avium_104 AYYGGSDANGFDFAQAGLQTGSSFKVFCLIAALEQGIGLGYQVDSSPLTV Mb0051|M.bovis_AF2122/97 AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYQVDSSPLTV Rv0050|M.tuberculosis_H37Rv AYYGGDNANGFDFAQAGLQTGSSFKVFALVAALEQGIGLGYQVDSSPLTV MLBr_02688|M.leprae_Br4923 AYYGGADANGFDFAQAGLQTGSSFKVFALIAALEQGIGLGYRVDSSPLTV MAB_4901c|M.abscessus_ATCC_199 AYYGGSNAQGLDYAQQGLQTGSSFKVFALVAALQQGIGLGYQLDSSELTY ***** :* * *:** .: ********.*:***:**:**** :**. : Mflv_0871|M.gilvum_PYR-GCK NGIKISNVEGSSCGSCNIAEALKRSLNTSYYRLMLKLKNGPQDVADAAHQ Mvan_6036|M.vanbaalenii_PYR-1 NGIKISNVEGNSCGTCNIAEALKRSLNTSYYRLMLQLENGPQDVADAAHA MSMEG_6900|M.smegmatis_MC2_155 NGIKIGNVEGEGCGTCSIAEALKRSLNTSYYRLMLKLENGPADVAEAAHD TH_3201|M.thermoresistible__bu NGIEITNVEGSSCGRCNIAEALKRSLNTSFYRLMLELKNGPEDVADAAHR MMAR_0069|M.marinum_M DGIKITNVEGESCGTCNIAQALKMSLNTSYYRLMLKLKGGPEAVADAAHQ MUL_0068|M.ulcerans_Agy99 DGIKITNVEGESCGTCNIAQALKMSLNTPYYRLMLKLKGGPEAVADAAHQ MAV_0071|M.avium_104 DGIKITNVEGESCGTCNIAQALKMSLNTSYYRLMLKLKGGPQAVADAAHQ Mb0051|M.bovis_AF2122/97 DGIKITNVEGEGCGTCNIAEALKMSLNTSYYRLMLKLNGGPQAVADAAHQ Rv0050|M.tuberculosis_H37Rv DGIKITNVEGEGCGTCNIAEALKMSLNTSYYRLMLKLNGGPQAVADAAHQ MLBr_02688|M.leprae_Br4923 DGIKITNNGDESCGNCNIAEALKLSLNTSYYRLMLKLKNGPQAVADAAHQ MAB_4901c|M.abscessus_ATCC_199 QGITIKNSEDASCGTCSVAEALKRSLNTSFYRLMLKLKNGPEDVAAAAHN :** * * . .** *.:*:*** ****.:*****:*:.** ** *** Mflv_0871|M.gilvum_PYR-GCK AGIAESIPGIEHTLSEDGQGGPPNNGIVLGQYQSRVLDMASAYATIAASG Mvan_6036|M.vanbaalenii_PYR-1 AGIAESFPGVEHTLSEDGQGGPPNNGVVLGQYQSRVIDMASAYATLAASG MSMEG_6900|M.smegmatis_MC2_155 AGVAESFPGVEHTLSEDGKGGPPNNGVVLGQYQSRVLDMASAYATLAASG TH_3201|M.thermoresistible__bu AGIAESIPGIEHTLSEDGKGGPPNNGIVLGQYQSRPIDMASAYATLANSG MMAR_0069|M.marinum_M AGIATSFPGVPHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG MUL_0068|M.ulcerans_Agy99 AGIATSFPGVPHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG MAV_0071|M.avium_104 AGVATSFPGVDHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG Mb0051|M.bovis_AF2122/97 AGIASSFPGVAHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG Rv0050|M.tuberculosis_H37Rv AGIASSFPGVAHTLSEDGKGGPPNNGIVLGQYQTRVIDMASAYATLAASG MLBr_02688|M.leprae_Br4923 AGIVSSFPGVAHTLSEDGKGGPPNNGIVLGQYETRVIDMASAYATLAASG MAB_4901c|M.abscessus_ATCC_199 AGIAENFPGVSHTLSEDGQGGPPNNGVVLGQYQTRVLDMASAYATLAASG **:. .:**: *******:*******:*****::* :********:* ** Mflv_0871|M.gilvum_PYR-GCK VYHKPHFVQKVVNSDGQVLFDATQEDNSGEQRIDQAVAENVIAAMQPIAG Mvan_6036|M.vanbaalenii_PYR-1 VYHKPHFVQKVVNAEGTVLFDASQEDNTGEQRIDKAVADNVTAAMQPIAA MSMEG_6900|M.smegmatis_MC2_155 VYHKPHFVEKVVNSSGQVLFDASKEDN-GEERIDKAVADNVTSAMQPIAG TH_3201|M.thermoresistible__bu VYHRPHFVQKVVNSEGQVLFDADQRDDDGEQRIEKDVADNVTAAMQPIAA MMAR_0069|M.marinum_M IYHRPHFVQKVVNADGRVLFDASTEDNTGDQRIPKAVADNVTAAMEPIAG MUL_0068|M.ulcerans_Agy99 IYHRPHFVQKVVDADGRVLFDASTEDNTGDQRIPKAVADNVTAAMEPIAG MAV_0071|M.avium_104 VYHRPHFVQKVVNSDGQVLFDAGKSDNNGEQRIPKAVADNVTAAMEPIAG Mb0051|M.bovis_AF2122/97 IYHPPHFVQKVVSANGQVLFDASTADNTGDQRIPKAVADNVTAAMEPIAG Rv0050|M.tuberculosis_H37Rv IYHPPHFVQKVVSANGQVLFDASTADNTGDQRIPKAVADNVTAAMEPIAG MLBr_02688|M.leprae_Br4923 VYHRPHLVQKVVNAEGRVLFDASTADNSGDQRIAKAVADNVTAAMQPIAG MAB_4901c|M.abscessus_ATCC_199 TYRKPHFIQKVVNADGQVLFDAGSSDNTGEKRISDDVANNAISAMKPIAA *: **:::***.:.* ***** *: *::** . **:*. :**:***. Mflv_0871|M.gilvum_PYR-GCK YS-GRALAGGRPSAAKTGTNQLGDTGENRDAWMVGFTPSLSTAVWVGTVD Mvan_6036|M.vanbaalenii_PYR-1 YSNGHALAGGRPSAAKTGTNQLGDTGANRDAWMVGFTPSLSTAVWVGTTD MSMEG_6900|M.smegmatis_MC2_155 WSRGHNLAGGRPSAAKTGTVQLGDTGDNRDAWMVGYTPSLSTAVWVGTTE TH_3201|M.thermoresistible__bu YSNGHALAGGRPSAAKTGTHQLGDTGENRDAWMVGYTPSLSTAVWVGTVD MMAR_0069|M.marinum_M YSRGHNLAGGRPSASKTGTVQLGDTSANRDAWMVGYTPSLSTAVWVGTVK MUL_0068|M.ulcerans_Agy99 YSRGHNLAGGRPSASKTGTVQLGDTSANRDAWMVGYTPSLSTAVWVGTVK MAV_0071|M.avium_104 YSRGHALAGGRPSAAKTGTTQLGDTTSNKDAWMVGYTPSLSTAVWLGTAK Mb0051|M.bovis_AF2122/97 YSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYTPSLSTAVWVGTVK Rv0050|M.tuberculosis_H37Rv YSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYTPSLSTAVWVGTVK MLBr_02688|M.leprae_Br4923 YSRGHNLAGGRPSAAKTGTVQLGDTTANKDAWMVGYTPSLSTAVWVGTVK MAB_4901c|M.abscessus_ATCC_199 YSRGHALAGGRESASKTGTAQLGDTKDNKDAWMVGFTPSLSTAVWVGTDD :* *: ***** **:**** *:*** *:******:*********:** . Mflv_0871|M.gilvum_PYR-GCK GTKPLVTSGGASVYGSGLPGQIWKSTMDNALDGTDNETFPKPEEIGGYAG Mvan_6036|M.vanbaalenii_PYR-1 GTKPLENKWGSPVYGSGLPSDIWKATMDGALDGTDNESFPKPEEIGGYAG MSMEG_6900|M.smegmatis_MC2_155 GVKPLVNKWGSPIYGSGLPSDIWKATMDGALEGTDVESFPKPTEIGGYAG TH_3201|M.thermoresistible__bu GNKPLRTKWGGKIYGSGLPSDIWKATMDGALKGTERESFPKPGEIGGYAG MMAR_0069|M.marinum_M GDEPLVTASGAPIYGSGLPSDIWKATMDGALKGTEVESFPKPTEIGGYAG MUL_0068|M.ulcerans_Agy99 GDEPLVTASGAPIYGSGLPSDIWKATMDGALKGTEVESFPKPTEIGGYAG MAV_0071|M.avium_104 GDQPLVTASGGPVYGSGLPSDIWKATMDGALKGTPNESFPKPAEVGGYAG Mb0051|M.bovis_AF2122/97 GDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAG Rv0050|M.tuberculosis_H37Rv GDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAG MLBr_02688|M.leprae_Br4923 DNVPLITASGEAIYGSGLPSDIWKSTMDGALEGTPNEGFPKPTEVGGYAG MAB_4901c|M.abscessus_ATCC_199 G-KPIKTSWGGPIYGSGLPSDIWKKTMDGALDGTAKETFPKPGPIGGYAG . *: . * :******.:*** ***.**.** * **** :***** Mflv_0871|M.gilvum_PYR-GCK VPQ-APPPPPSS-----TAPPTPSETVIQPTLEIAPGITIPWG------- Mvan_6036|M.vanbaalenii_PYR-1 VPQ-APPPPPSPS---VTVPPPPSETVIQPTLEIAPGITIPWG------- MSMEG_6900|M.smegmatis_MC2_155 VPQ-APAAPPPSAGP-PTDPGQPSVTVIQPTIEVAPGITIPIG------- TH_3201|M.thermoresistible__bu VPQ-APSPQRTSDDDGTTTVTPPSETVIQPSVEVAPGITIPLGXAVSAVV MMAR_0069|M.marinum_M VPA-PPPPPPEAP--------PPSETVIQPTVEIAPGITIPVG------- MUL_0068|M.ulcerans_Agy99 VPA-PPPPPPEAP--------PPAETVIQPTVEIVPGITIPVG------- MAV_0071|M.avium_104 VPA-PPPPP--KA--------PPSETVIQPTIEVAPGITIPVG------- Mb0051|M.bovis_AF2122/97 VPP-PPPPPPSEV--------PPSETVIQPTVEIAPGITIPIG------- Rv0050|M.tuberculosis_H37Rv VPP-PPPPP--EV--------PPSETVIQPTVEIAPGITIPIG------- MLBr_02688|M.leprae_Br4923 VPT-LAPPP-------------PLKKVIQPTIEVAPGIIIPVG------- MAB_4901c|M.abscessus_ATCC_199 VPTYVPPPPVPNGPPAPAPTGGGEVTVIQPTIEIAPGITIPVG------- ** ... .****::*:.*** ** * Mflv_0871|M.gilvum_PYR-GCK --------------PPTT-------------------------------- Mvan_6036|M.vanbaalenii_PYR-1 --------------PPTT-------------------------------- MSMEG_6900|M.smegmatis_MC2_155 --------------PPTT-------------------------------- TH_3201|M.thermoresistible__bu RVRDAVVRPHLVAEPPLTGRPDGTSRPGRRAPVRRCRNVDFRRDIGAPCA MMAR_0069|M.marinum_M --------------PPTT-------------------------------- MUL_0068|M.ulcerans_Agy99 --------------PPTT-------------------------------- MAV_0071|M.avium_104 --------------PPTT-------------------------------- Mb0051|M.bovis_AF2122/97 --------------PPTT-------------------------------- Rv0050|M.tuberculosis_H37Rv --------------PPTT-------------------------------- MLBr_02688|M.leprae_Br4923 --------------PPTT-------------------------------- MAB_4901c|M.abscessus_ATCC_199 --------------PPTT-------------------------------- ** * Mflv_0871|M.gilvum_PYR-GCK --------------------------------------------VPVGP- Mvan_6036|M.vanbaalenii_PYR-1 --------------------------------------------VPVAPP MSMEG_6900|M.smegmatis_MC2_155 --------------------------------------------VPVGPP TH_3201|M.thermoresistible__bu FHRDRRWLPADAVRAEPLGRGSPQRTGPGRAGGLLSGAAVRGTGVPSEPA MMAR_0069|M.marinum_M --------------------------------------------ITLAP- MUL_0068|M.ulcerans_Agy99 --------------------------------------------ITLAP- MAV_0071|M.avium_104 --------------------------------------------VTLAP- Mb0051|M.bovis_AF2122/97 --------------------------------------------ITLAP- Rv0050|M.tuberculosis_H37Rv --------------------------------------------ITLAP- MLBr_02688|M.leprae_Br4923 --------------------------------------------VTVPP- MAB_4901c|M.abscessus_ATCC_199 --------------------------------------------VPVGP- :. * Mflv_0871|M.gilvum_PYR-GCK -PGAPP--VPETAPPVPPPGAPVPPGAPPPPGA-------PVPPGAPPGP Mvan_6036|M.vanbaalenii_PYR-1 VPGAPP--APGAPPPAGAPGAPVPPGAPPP------------------GP MSMEG_6900|M.smegmatis_MC2_155 -PGAPG--APVGP---GAPEVPVAPGAPGVP-----------------GA TH_3201|M.thermoresistible__bu HGGSVPRRAGGADDGADAPGAGRAPGAQRRVR--------HHPGGPDGGP MMAR_0069|M.marinum_M -----------------PPPPGAPP-----------------------AD MUL_0068|M.ulcerans_Agy99 -----------------PPPPGAPP-----------------------AD MAV_0071|M.avium_104 -----------------APPAGGPPGGPEPGGGVPPGPGGGVPPGGPQAP Mb0051|M.bovis_AF2122/97 -----------------PPP--APP---------------------AATP Rv0050|M.tuberculosis_H37Rv -----------------PPP--APP---------------------AATP MLBr_02688|M.leprae_Br4923 -----------------TQALPDLT-----------------------TS MAB_4901c|M.abscessus_ATCC_199 ----------------AAPPAGDVP------------------------P . . Mflv_0871|M.gilvum_PYR-GCK LPPP---------- Mvan_6036|M.vanbaalenii_PYR-1 LPPP---------- MSMEG_6900|M.smegmatis_MC2_155 PPPP---------- TH_3201|M.thermoresistible__bu RQPAAVSPLRGTTR MMAR_0069|M.marinum_M NPPP---------- MUL_0068|M.ulcerans_Agy99 NPPP---------- MAV_0071|M.avium_104 PPPP---------- Mb0051|M.bovis_AF2122/97 TPPP---------- Rv0050|M.tuberculosis_H37Rv TPPP---------- MLBr_02688|M.leprae_Br4923 TTPP---------- MAB_4901c|M.abscessus_ATCC_199 PGP----------- *