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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2122 | ponA | - | 100% (879) | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) |
M. thermoresistible (build 8) | TH_3201 | - | 7e-46 | 27.15% (652) | PUTATIVE glycosyl transferase, family 51 |
M. thermoresistible (build 8) | TH_1396 | - | 2e-07 | 25.89% (336) | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3707 | ponA2 | 0.0 | 78.97% (756) | bifunctional membrane-associated penicillin-binding protein |
M. gilvum PYR-GCK | Mflv_1365 | - | 0.0 | 80.50% (764) | glycosyl transferase family protein |
M. tuberculosis H37Rv | Rv3682 | ponA2 | 0.0 | 78.97% (756) | bifunctional membrane-associated penicillin-binding protein |
M. leprae Br4923 | MLBr_02308 | pon1 | 0.0 | 77.63% (742) | penicillin binding protein (class A) |
M. abscessus ATCC 19977 | MAB_0408c | - | 0.0 | 69.34% (786) | bifunctional membrane-associated penicillin-binding protein |
M. marinum M | MMAR_5171 | ponA2 | 0.0 | 78.00% (759) | bifunctional membrane-associated penicillin- binding |
M. avium 104 | MAV_0446 | - | 0.0 | 79.42% (729) | transglycosylase |
M. smegmatis MC2 155 | MSMEG_6201 | - | 0.0 | 87.12% (730) | transglycosylase |
M. ulcerans Agy99 | MUL_4257 | ponA2 | 0.0 | 77.60% (759) | bifunctional membrane-associated penicillin- binding |
M. vanbaalenii PYR-1 | Mvan_5442 | - | 0.0 | 80.90% (759) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment TH_2122|M.thermoresistible__bu MPEDPPTAPTESTRAATVIKLAWCCLLAAVIAAALMFPVVGGIGLLSNRA MSMEG_6201|M.smegmatis_MC2_155 -----------------------------MLAAALMFPVVGGFGLMSNRA Mflv_1365|M.gilvum_PYR-GCK MPEQPPTQP---PRAVTVIKLAWCVVLASVIVAGLLFPVVGGFGLVSNRA Mvan_5442|M.vanbaalenii_PYR-1 MPEHPSGPP---PRAVTVIKLAWCVLLASVVAAGLMFPVVGGFGLMPNRA Mb3707|M.bovis_AF2122/97 MPERL-------PAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRA Rv3682|M.tuberculosis_H37Rv MPERL-------PAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRA MMAR_5171|M.marinum_M MSERP-------PAALTLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRA MUL_4257|M.ulcerans_Agy99 MSERP-------PAALSLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRA MAV_0446|M.avium_104 ------------------------------MATALLFPVAGGIGLVSNRA MLBr_02308|M.leprae_Br4923 MSERL-------PAVLAVLKLAGYCLLAGVVTTAMMFPLAGGLGVISNRA MAB_0408c|M.abscessus_ATCC_199 MPERLSP---QIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRA : :.: **..**:*: .*** TH_2122|M.thermoresistible__bu SDVVANGSAQLVEGDVPAVSTMVDAEGNPIAWLYSQRRWEVPSEEIADTM MSMEG_6201|M.smegmatis_MC2_155 SDVVANGSAALVEGEVPQVSTMVDAKGNTIAWLYSQRRFEVPSEQIANTM Mflv_1365|M.gilvum_PYR-GCK SDVVANGSAQLVEGEVPQVSTMTDSKGNIIAWLYSQRRFEVPSDQIANTM Mvan_5442|M.vanbaalenii_PYR-1 SDVVANGSAQLVEGEVPQVSTMTDAKGNVIAWLYNQRRFEVPSDQIANTM Mb3707|M.bovis_AF2122/97 SEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM Rv3682|M.tuberculosis_H37Rv SEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM MMAR_5171|M.marinum_M SEVVANGSAQLLQGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM MUL_4257|M.ulcerans_Agy99 SEVVANGSAQLLQGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM MAV_0446|M.avium_104 SEVVANGSAQLLEGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM MLBr_02308|M.leprae_Br4923 SEVVANGSAQLLEGEVPAVSTMVDAKGNTIAWLYSQRRFEVPTDKIANTM MAB_0408c|M.abscessus_ATCC_199 SDVVANGSTQLLQGEVPAVTTVEDAKGNKIAYLYTQRRFEVSADEIADTM *:******: *::*:** *:*: *::** **:**.***:**.:::**:** TH_2122|M.thermoresistible__bu KLAIVAIEDKRFAEHNGVDWQGTLTGLTGYLRGDSDTRGGSTLEQQYVKN MSMEG_6201|M.smegmatis_MC2_155 KLAIVSIEDKRFAEHNGVDWQGTLTGLSGYLSGNPDTRGGSTIEQQYVKN Mflv_1365|M.gilvum_PYR-GCK KLAIVSIEDKRFADHNGVDWQGTLTGLSGYLSGNLDTRGGSTIEQQYVKN Mvan_5442|M.vanbaalenii_PYR-1 KLAIVSIEDKRFADHNGVDWQGTLTGLSGYLSGNLDTRGGSTIEQQYVKN Mb3707|M.bovis_AF2122/97 KLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKN Rv3682|M.tuberculosis_H37Rv KLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKN MMAR_5171|M.marinum_M KLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQYIKN MUL_4257|M.ulcerans_Agy99 KLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQYIKN MAV_0446|M.avium_104 KLAIVSIEDKRFADHNGVDWKGTLTGLAGYARGDVDTRGGSTIEQQYIKN MLBr_02308|M.leprae_Br4923 KLAIVSIEDKRFTDHNGVDWPGTLTGLAGYASGDVDTRGGSTIEQQYVKN MAB_0408c|M.abscessus_ATCC_199 KLALLSIEDKRFTSHNGVDWKGTLGGLAGYASGDEDTRGGSTIEQQYVKN ***:::******:.*.**** *** **:** *: *******:****:** TH_2122|M.thermoresistible__bu YQLLVVAQTDAEKRAAIETTPARKLREIRMALTLDKTLTKPEILTRYLNL MSMEG_6201|M.smegmatis_MC2_155 YQLLVVAQTDAERRAAIETTPARKLREIRMALTLDKTFTKPEILTRYLNL Mflv_1365|M.gilvum_PYR-GCK YQLLVIAQTDAEKRAAIETTPARKLREIRMALTLDKTFTKPEILTRYLNL Mvan_5442|M.vanbaalenii_PYR-1 YQLLVIAQTDAEKRAAIETTPARKLREIRMALTLDKTFTKPEILTRYLNL Mb3707|M.bovis_AF2122/97 YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNL Rv3682|M.tuberculosis_H37Rv YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNL MMAR_5171|M.marinum_M YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL MUL_4257|M.ulcerans_Agy99 YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL MAV_0446|M.avium_104 YQLLVTAKTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL MLBr_02308|M.leprae_Br4923 YQLLVTAQTDAEKRAAVETTPARKLREIRIALTLDKTFTKPEILTRYLNL MAB_0408c|M.abscessus_ATCC_199 YQLLVVAKTDAERKAAIETTPARKLREIRMALRLDQTFTKQEILTRYLNL ***** *:****::**:************:** **:*:** ********* TH_2122|M.thermoresistible__bu VSFGNGAYGIQDAAQTYFGINASELDWHQAALLAGLVQSTTALNPYTNPD MSMEG_6201|M.smegmatis_MC2_155 VSFGNGAYGIQDAAQTYFGVNASELNWQQAALLAGMVQSTSALNPYTNPD Mflv_1365|M.gilvum_PYR-GCK VSFGNNAFGVQDAAQTYFGINATDLNWQQAALLAGMVQSTSTLNPYTNPD Mvan_5442|M.vanbaalenii_PYR-1 VSFGNNAFGVQDAAQTYFGVNASELNWQQAALLAGMVQSTSTLNPYTNPD Mb3707|M.bovis_AF2122/97 VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPD Rv3682|M.tuberculosis_H37Rv VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPD MMAR_5171|M.marinum_M VSFGNNSFGVQDAAQTYFGINASELNWQQSALLAGMVQSTSTLNPYTNPD MUL_4257|M.ulcerans_Agy99 VSFGNNSFGVQDAAQTYFGINASELNWQQSALLAGMVQSTSTLNPYTNPD MAV_0446|M.avium_104 VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSALNPYTNPE MLBr_02308|M.leprae_Br4923 VSFGNNSFGVQDAAQTYFGVNASDLNWQQAALLAGMVQSTSTLNPYTNPE MAB_0408c|M.abscessus_ATCC_199 VSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGLNPYVNPE *****.::*:*********::*.:*:*:*:*****:****: ****.**: TH_2122|M.thermoresistible__bu GALARRNLVLDTMIDQLPQEAEALRAAKEQPLGILPRPNELPRGCIAAGD MSMEG_6201|M.smegmatis_MC2_155 GALARRNLVLDTMIQNIPQEAEALRAAKEQPLGILPQPNELPRGCIAAGD Mflv_1365|M.gilvum_PYR-GCK GALARRNVVLDTMIENLPEYADELRAARQEPLGVLPQPKELPRGCIAAGD Mvan_5442|M.vanbaalenii_PYR-1 GALARRNVVLDTMIENLPEHADELRTAKQQPLGILPQPKELPRGCIAAGD Mb3707|M.bovis_AF2122/97 GALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGD Rv3682|M.tuberculosis_H37Rv GALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGD MMAR_5171|M.marinum_M GALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQPNELPRGCIAAGD MUL_4257|M.ulcerans_Agy99 GALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQPNELPRGCIAAGD MAV_0446|M.avium_104 GALARRNLVLDTMIENIPQEADALRAAKAAPLGILPQPNELPRGCIAAGD MLBr_02308|M.leprae_Br4923 GALARRNLVLDTMIENLPQDAEALRAAKTEPLGILPRPNELPRGCIAAGD MAB_0408c|M.abscessus_ATCC_199 RALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGD ******:****** : * * :*: ***:**:*:*********** TH_2122|M.thermoresistible__bu RAFFCDYVLEYLARAGISKEQVAKGGYLIKTTLDPEVQRAVKSAIDQYAR MSMEG_6201|M.smegmatis_MC2_155 RAFFCDYVLEYLARAGISKEQVAKGGYLIKTTLDPDVQSSVKSAIDSIAA Mflv_1365|M.gilvum_PYR-GCK RAFFCDYALDYLARAGISKDQVAKGGYMIKTTLDPDVQASVKNAITQYAS Mvan_5442|M.vanbaalenii_PYR-1 RAFFCDYALDYLARAGISKDQVAKGGYLIKTTLEPDVQASVKNAINEFAS Mb3707|M.bovis_AF2122/97 RAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYAS Rv3682|M.tuberculosis_H37Rv RAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYAS MMAR_5171|M.marinum_M RAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFAS MUL_4257|M.ulcerans_Agy99 RAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFAS MAV_0446|M.avium_104 RAYFCDYVQEYLSRAGISKEQVARGGYLIKTTLDPDVQIPVKAAIDKFAS MLBr_02308|M.leprae_Br4923 RAFFCDYVQEYLSHAGISKDRLAKGGYLIRTTLDPNVQAPVKAAIDKFAS MAB_0408c|M.abscessus_ATCC_199 RAFFCDYVLDYLAKSGISKDQVMKGGYLIRTTLDPDVQNSVKQAVSHVAD **:****. :**:::****::: ***:*:***:*:** .** *: * TH_2122|M.thermoresistible__bu PDANGVASVMSVIRPGKESHPVLAMASSRHYGLNSEAGETMQPQPFSLVG MSMEG_6201|M.smegmatis_MC2_155 PDTPGVASVMSVIKPGKESHPVLAMASNRTYGLDTERGETMQPQPFSLVG Mflv_1365|M.gilvum_PYR-GCK PDLPGVASVMSVVKPGKDSHPVLAMASNRTYGLNLDAGETMQPQPFSLVG Mvan_5442|M.vanbaalenii_PYR-1 PDLPGVASVMSVIRPGKDSHPVLAMASNRTYGLNLDAGETMQPQPFSLVG Mb3707|M.bovis_AF2122/97 PNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVG Rv3682|M.tuberculosis_H37Rv PNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVG MMAR_5171|M.marinum_M PTLPGISSVMSVIKPGKESHQVLAMASNRKYGLDINAGETMRPQPFSLVG MUL_4257|M.ulcerans_Agy99 PTLPGISSVMSVIKPGKESHQVLAMASNRAYGLDINAGETMRPQPFSLVG MAV_0446|M.avium_104 PTLPGISSVMSVIQPGKTSHKVMAMASNRTYGLDVDAGQTMRPQPFSLVG MLBr_02308|M.leprae_Br4923 PNLAGISSVMSVITPGKDAHRVIAMGSNRRYGLDTEAGETMRPQTFSLVG MAB_0408c|M.abscessus_ATCC_199 PGLNGIANVMSVIKPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVG * *::.****: **: :* ::**.*.* ***: : :**:**.***** TH_2122|M.thermoresistible__bu HGAGSVFKIFTTAAAMEMGMGINTQLEAPAFFQAKGLGSS-DTPGCPAAT MSMEG_6201|M.smegmatis_MC2_155 NGAGSVFKIFTVAAAMEMGMGINTQLPVPARFEAKGLGSG-GARGCPPAT Mflv_1365|M.gilvum_PYR-GCK NGAGSVFKIFTTAAAMEMGMGINAQLDSPSRFEAKGLGSG-GARGCPPAT Mvan_5442|M.vanbaalenii_PYR-1 NGAGSVFKIFTTAAAMEMGMGINAQLDSPSRFEAKGLGSG-GARGCPPAT Mb3707|M.bovis_AF2122/97 DGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSG-GAKGCPKET Rv3682|M.tuberculosis_H37Rv DGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSG-GAKGCPKET MMAR_5171|M.marinum_M DGAGSIFKIFTTAAALDMGMGINAQLDVPGRFQGKGLGSG-GAKGCPKDT MUL_4257|M.ulcerans_Agy99 DGAGSIFKIFTTAAALDMGMGISAQLDVPGRFQGKGLGSG-GAKGCPKDT MAV_0446|M.avium_104 DGAGSVFKIFTTAAALDMGMGINATLEVPGRFQAKGMGSG-GAKGCPKDT MLBr_02308|M.leprae_Br4923 DGAGSVFKIFTTAAALDMGMGINAKLEVPSRFQAKGMGSG-GAKGCPKET MAB_0408c|M.abscessus_ATCC_199 DGAGSIFKIFTVAAAMDMGMGINTVLDVPPTFAAKGLGSSDGSKGCPKDN .****:*****.***::*****.: * * * .**:**. .: *** . TH_2122|M.thermoresistible__bu WCVRNAGSYRGSMNVTDALATSPNTAFAKLISQIGVPRTVDMAVRLGLRS MSMEG_6201|M.smegmatis_MC2_155 WCVQNAGGYRGSMSVTDALATSPNTAFAKLISQIGVQRAVDMAVRLGLRS Mflv_1365|M.gilvum_PYR-GCK WCVQNAGNYRGTMSVTDALATSPNTAFAKLIAQVGVQRTVDMAVRLGLRS Mvan_5442|M.vanbaalenii_PYR-1 WCVQNAGNYRGTMNVTDALATSPNTAFAKLIAQVGVQRTVDMAVKLGLRS Mb3707|M.bovis_AF2122/97 WCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRS Rv3682|M.tuberculosis_H37Rv WCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRS MMAR_5171|M.marinum_M WCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGLRS MUL_4257|M.ulcerans_Agy99 WCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGLRS MAV_0446|M.avium_104 WCVVNAGNYKGSMNVTEALATSPNTAFAKLIQQVGVTRTVDMAIKLGLRS MLBr_02308|M.leprae_Br4923 WCVINAGNYRGSMNVTDALATSPNTAFAKLIQQVGVARTVDMAIKLGLRS MAB_0408c|M.abscessus_ATCC_199 WCVKNVGNYRSPMSVTDALATSPNTAFAKLIQSIGVSKAVDMAVKLGMRS *** *.*.*:..*.**:************** .:** ::****::**:** TH_2122|M.thermoresistible__bu YAQPGTARDYDPNSDESIADWVKRQNIGSFTLGPIEVNALELSNVAATLA MSMEG_6201|M.smegmatis_MC2_155 YAQPGTARDYDPESSESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA Mflv_1365|M.gilvum_PYR-GCK YALPGTARDYDPESNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA Mvan_5442|M.vanbaalenii_PYR-1 YALPGTARDYDPESNESLADFVKRQNLGSFTLGPIEVNALELSNVAATLA Mb3707|M.bovis_AF2122/97 YANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLA Rv3682|M.tuberculosis_H37Rv YANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLA MMAR_5171|M.marinum_M YANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA MUL_4257|M.ulcerans_Agy99 YANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA MAV_0446|M.avium_104 YADPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA MLBr_02308|M.leprae_Br4923 YTTPGTARDYNPDSNESLADFVKRQNIGSFTLGPIKVNALELSNVAATLA MAB_0408c|M.abscessus_ATCC_199 YAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELSNVAATLA *: ****: *:*:..**:*:::*: *:********::*.*********** TH_2122|M.thermoresistible__bu SGGVWCPPNPIDKVYDRHGNEVSVTTETCEQVVPEGLANTLANAMSEDDR MSMEG_6201|M.smegmatis_MC2_155 SGGTWCPPNPIAQVVDRNGNEVAVTTETCEQVVPEGLANTLANAMSKDDT Mflv_1365|M.gilvum_PYR-GCK SGGMWCPPNPIAEVYDRYGEPVSVTTETCEQAVPEGLANTLANAMSKDDT Mvan_5442|M.vanbaalenii_PYR-1 SGGMWCPPNPIAEVRDRYGELVSVTTETCEQVVPEGLANTLAVAMSKDDT Mb3707|M.bovis_AF2122/97 SGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAV Rv3682|M.tuberculosis_H37Rv SGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAV MMAR_5171|M.marinum_M SGGVWCPPNPVDKLIDRNGNEVAVTTETCDQVVPEGLANTLANAMSKDAV MUL_4257|M.ulcerans_Agy99 SGGVWCPPNPVDKLIDRNGNEVAVTTETCDQVVPEGLANTLANAMSKDAV MAV_0446|M.avium_104 SGGTWCPPNPIDKLIDRKGNEVAVTTETCDQVVPEGLANTMANAMSKDAV MLBr_02308|M.leprae_Br4923 SGGMWCPPNPIDKLFDRNGNEVAVTVETCDRVVPEGLANTLANAMSKDTK MAB_0408c|M.abscessus_ATCC_199 SGGKWCPPNPIDKVFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQ *** ******: :: ** *: *..*.*:*::.** *****:* *:*:* TH_2122|M.thermoresistible__bu GAGTAAGAAASVGWDLPMSGKTGTTESNRSSAFLGFTNQLAAANYIYDDS MSMEG_6201|M.smegmatis_MC2_155 GSGTAAASAGSVGWNLPMSGKTGTTEDNRSSAFLGFTNQYAAANYIYDDS Mflv_1365|M.gilvum_PYR-GCK GAGTAAGAAGSVGWNLPMSGKTGTTEANRSSAFLGFTNRYAAASYIYDDS Mvan_5442|M.vanbaalenii_PYR-1 GAGTAAGAAGSTGWSLPMSGKTGTTESNRSSAFLGFTNQYAAASYIYDDS Mb3707|M.bovis_AF2122/97 GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS Rv3682|M.tuberculosis_H37Rv GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS MMAR_5171|M.marinum_M GGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS MUL_4257|M.ulcerans_Agy99 GGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS MAV_0446|M.avium_104 GGGTAAGSAGAAGWDLPMSGKTGTTEAHRSSGFVGFTNHYAAANYIYDDS MLBr_02308|M.leprae_Br4923 GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSSGFVGFTNHYAAANYIYDDS MAB_0408c|M.abscessus_ATCC_199 PGGTAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGASYIYDDS .***:.:*.:.**.**:*.****** :**:.*:*:**. *.*.****** TH_2122|M.thermoresistible__bu NSPGELCSFPLRRCGSGDLFGGNEPARTWFAAMKPIAEKFGPVALPPTDP MSMEG_6201|M.smegmatis_MC2_155 PNPSELCSFPLRQCGSGNLFGGNEPARTWFTAMKPIAESFGPVALPPTDP Mflv_1365|M.gilvum_PYR-GCK TAPTELCSFPLRQCGSGNLFGGNEPARTWFSAMQPIATAFGDVTLPPTDP Mvan_5442|M.vanbaalenii_PYR-1 TAPTELCSFPLRQCGSGNLFGGNEPARTWFTAMTPIATAFGDVTLPPTDP Mb3707|M.bovis_AF2122/97 SSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDP Rv3682|M.tuberculosis_H37Rv SSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDP MMAR_5171|M.marinum_M TNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDP MUL_4257|M.ulcerans_Agy99 TNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDP MAV_0446|M.avium_104 PNPTDLCSAPLRHCGEGDLYGGNEPARTWFTAMKPIATNFGPVQLPPTDP MLBr_02308|M.leprae_Br4923 TSPTNLCSGPLRHCSNGDLYGGNEPARTWFTAMKPIATKFGEVRLPPTDP MAB_0408c|M.abscessus_ATCC_199 TTPGDLCSFPLRKCGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEP * :*** ***:*..*:*:*****:*:** *: *** :* . ****:* TH_2122|M.thermoresistible__bu RYVDGGPGSRVPSVSGLSEEAARQRLRDAGFQVADGVATVNSSARRGTVV MSMEG_6201|M.smegmatis_MC2_155 RYVDGGPGSRVPSVSGLTEEAARQRLKEAGFQVADQASYVNSGARSGTVV Mflv_1365|M.gilvum_PYR-GCK RYVEGAPGSKVPSVAGMDQDTARARLREAGFQVADQATPVNSSSRYGTVV Mvan_5442|M.vanbaalenii_PYR-1 RYVDGAPGSKVPSVAGMNQDTARQRLREAGFQVADQPTPVNSTAPYGAVV Mb3707|M.bovis_AF2122/97 RYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVV Rv3682|M.tuberculosis_H37Rv RYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVV MMAR_5171|M.marinum_M RYVDGAPGSRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEVV MUL_4257|M.ulcerans_Agy99 RYVDGAPGSRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEAV MAV_0446|M.avium_104 RYVDGAPGSRVPSVAGLDIDAARQRIKEAGFQVADQNNFVNSSAKQGEVV MLBr_02308|M.leprae_Br4923 RYVDGSPGSQVPSVTGLDLDAARQRLKGAGFQVADQPTLINSTAKLGAVV MAB_0408c|M.abscessus_ATCC_199 RYVEGGPGSKVPSINGLREPEARDVLKKAGFRVADQASSVNSTAPFNEVV ***:*.***:***: *: ** :: ***:*** :** : . .* TH_2122|M.thermoresistible__bu GTNPSGQTIPXXYPTQFLRADLDALGVIPADKLLEVPDGTRILIAGAVTH MSMEG_6201|M.smegmatis_MC2_155 GTTPSGQTIPGSIITIQLSNGIPPPPPPPVN--IPLPGGP---------- Mflv_1365|M.gilvum_PYR-GCK GTAPSGQTVPGSIVTIQISNGIAPAPPPPPAG-APPPGGPP--------- Mvan_5442|M.vanbaalenii_PYR-1 GTSPTGQTVPGSIITIQISNGIAPPPPPPPPG-APP-GLPP--------- Mb3707|M.bovis_AF2122/97 GTSPSGQTIPGSIVTIQISNGIPPAPPPPPLPEDGGPPPP---------- Rv3682|M.tuberculosis_H37Rv GTSPSGQTIPGSIVTIQISNGIPPAPPPPPLPEDGGPPPP---------- MMAR_5171|M.marinum_M GTSPSGQTIPGSIITIQISNGIPPAPPPPP---EGEPPPP---------- MUL_4257|M.ulcerans_Agy99 GTSPSGQTIPGSIITIQISNGIPPAPPPPP---EGEPPPP---------- MAV_0446|M.avium_104 GTTPSGATIPGSIITIQVSNGIPPAPPPPP----EGAPPP---------- MLBr_02308|M.leprae_Br4923 GTTPSGQTIPGSIITIQTSSGIPPAPPPPP---EGGPPMPP--------- MAB_0408c|M.abscessus_ATCC_199 GTSPSGTTIPGSVITILMSNGIPPAPPPLVIPGIPGAPPGE--------- ** *:* *:* * .: . TH_2122|M.thermoresistible__bu RQRPATAQGVTFLN-LEDETGMVNVLCSPGVWARHRRLAQTAPALLVRGI MSMEG_6201|M.smegmatis_MC2_155 ---PEIGQTVVEIPGLPPIT--VPVLGPP---------PPPPPP------ Mflv_1365|M.gilvum_PYR-GCK ---PPAGETVIQIPGLPPIT--VPVLGPP---------PPPPPPPG---- Mvan_5442|M.vanbaalenii_PYR-1 ---PPVGQTVIQIPGLPPIT--VPVLGPP---------PPPPPPPG---- Mb3707|M.bovis_AF2122/97 -----VGSQVVEIPGLPPIT--IPLLAPP----------PPAP--PP--- Rv3682|M.tuberculosis_H37Rv -----VGSQVVEIPGLPPIT--IPLLAPP----------PPAP--PP--- MMAR_5171|M.marinum_M -----VGSQVVEIPGLPPIT--IPLLAPP----------PP--------- MUL_4257|M.ulcerans_Agy99 -----VGSQVVEIPGLPPIT--IPLLAPP----------PP--------- MAV_0446|M.avium_104 -----VGSQVVEIPGLPPIT--IPLLAPP----------PPAPGQPPP-- MLBr_02308|M.leprae_Br4923 ----SVGSQVIEIPGLPPIT--IPLLAPP--------------------- MAB_0408c|M.abscessus_ATCC_199 -----MTTTIVNIPGLPPIT--VPVLAPP-------------P------- : : * * : :* .* TH_2122|M.thermoresistible__bu VQNATGAVTVVADRMRRLELRVGSRSRDFR MSMEG_6201|M.smegmatis_MC2_155 ------------------------------ Mflv_1365|M.gilvum_PYR-GCK ------------------------------ Mvan_5442|M.vanbaalenii_PYR-1 ------------------------------ Mb3707|M.bovis_AF2122/97 ------------------------------ Rv3682|M.tuberculosis_H37Rv ------------------------------ MMAR_5171|M.marinum_M ------------------------------ MUL_4257|M.ulcerans_Agy99 ------------------------------ MAV_0446|M.avium_104 ------------------------------ MLBr_02308|M.leprae_Br4923 ------------------------------ MAB_0408c|M.abscessus_ATCC_199 ------------------------------