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MSERPPAALTLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRASEVVANGSAQLLQGEVPAVSTMVDAKG NTIAWLYSQRRFEVPSDKIANTMKLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQY IKNYQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNLVSFGNNSFGVQDAAQTY FGINASELNWQQSALLAGMVQSTSTLNPYTNPDGALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQ PNELPRGCIAAGDRAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFASPTLPGIS SVMSVIKPGKESHQVLAMASNRKYGLDINAGETMRPQPFSLVGDGAGSIFKIFTTAAALDMGMGINAQLD VPGRFQGKGLGSGGAKGCPKDTWCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGL RSYANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLASGGVWCPPNPVDKLIDRN GNEVAVTTETCDQVVPEGLANTLANAMSKDAVGGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTN RYAAANYIYDDSTNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDPRYVDGAPG SRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEVVGTSPSGQTIPGSIITIQISNGIPPAPPP PPEGEPPPPVGSQVVEIPGLPPITIPLLAPPPP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5171 | ponA2 | - | 100% (803) | bifunctional membrane-associated penicillin- binding protein 1A/1B PonA2 |
| M. marinum M | MMAR_0069 | ponA1 | 5e-48 | 26.23% (770) | bifunctional penicillin-binding protein 1A/1B PonA1 |
| M. marinum M | MMAR_3200 | pbpB | 4e-10 | 24.23% (326) | penicillin-binding membrane protein PbpB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3707 | ponA2 | 0.0 | 91.19% (806) | bifunctional membrane-associated penicillin-binding protein |
| M. gilvum PYR-GCK | Mflv_1365 | - | 0.0 | 79.38% (805) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv3682 | ponA2 | 0.0 | 91.19% (806) | bifunctional membrane-associated penicillin-binding protein |
| M. leprae Br4923 | MLBr_02308 | pon1 | 0.0 | 86.92% (803) | penicillin binding protein (class A) |
| M. abscessus ATCC 19977 | MAB_0408c | - | 0.0 | 72.37% (807) | bifunctional membrane-associated penicillin-binding protein |
| M. avium 104 | MAV_0446 | - | 0.0 | 91.28% (780) | transglycosylase |
| M. smegmatis MC2 155 | MSMEG_6201 | - | 0.0 | 81.89% (784) | transglycosylase |
| M. thermoresistible (build 8) | TH_2122 | ponA | 0.0 | 78.00% (759) | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING |
| M. ulcerans Agy99 | MUL_4257 | ponA2 | 0.0 | 99.50% (803) | bifunctional membrane-associated penicillin- binding |
| M. vanbaalenii PYR-1 | Mvan_5442 | - | 0.0 | 80.45% (803) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1365|M.gilvum_PYR-GCK MPEQPPTQP---PRAVTVIKLAWCVVLASVIVAGLLFPVVGGFGLVSNRA
Mvan_5442|M.vanbaalenii_PYR-1 MPEHPSGPP---PRAVTVIKLAWCVLLASVVAAGLMFPVVGGFGLMPNRA
MSMEG_6201|M.smegmatis_MC2_155 -----------------------------MLAAALMFPVVGGFGLMSNRA
TH_2122|M.thermoresistible__bu MPEDPPTAPTESTRAATVIKLAWCCLLAAVIAAALMFPVVGGIGLLSNRA
MMAR_5171|M.marinum_M MSERP-------PAALTLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRA
MUL_4257|M.ulcerans_Agy99 MSERP-------PAALSLLKLSGFCLLASIVAAALMFPFAGGIGLMSNRA
Mb3707|M.bovis_AF2122/97 MPERL-------PAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRA
Rv3682|M.tuberculosis_H37Rv MPERL-------PAAITVLKLAGCCLLASVVATALTFPFAGGLGLMSNRA
MAV_0446|M.avium_104 ------------------------------MATALLFPVAGGIGLVSNRA
MLBr_02308|M.leprae_Br4923 MSERL-------PAVLAVLKLAGYCLLAGVVTTAMMFPLAGGLGVISNRA
MAB_0408c|M.abscessus_ATCC_199 MPERLSP---QIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRA
: :.: **..**:*: .***
Mflv_1365|M.gilvum_PYR-GCK SDVVANGSAQLVEGEVPQVSTMTDSKGNIIAWLYSQRRFEVPSDQIANTM
Mvan_5442|M.vanbaalenii_PYR-1 SDVVANGSAQLVEGEVPQVSTMTDAKGNVIAWLYNQRRFEVPSDQIANTM
MSMEG_6201|M.smegmatis_MC2_155 SDVVANGSAALVEGEVPQVSTMVDAKGNTIAWLYSQRRFEVPSEQIANTM
TH_2122|M.thermoresistible__bu SDVVANGSAQLVEGDVPAVSTMVDAEGNPIAWLYSQRRWEVPSEEIADTM
MMAR_5171|M.marinum_M SEVVANGSAQLLQGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MUL_4257|M.ulcerans_Agy99 SEVVANGSAQLLQGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
Mb3707|M.bovis_AF2122/97 SEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
Rv3682|M.tuberculosis_H37Rv SEVVANGSAQLLEGQVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MAV_0446|M.avium_104 SEVVANGSAQLLEGEVPAVSTMVDAKGNTIAWLYSQRRFEVPSDKIANTM
MLBr_02308|M.leprae_Br4923 SEVVANGSAQLLEGEVPAVSTMVDAKGNTIAWLYSQRRFEVPTDKIANTM
MAB_0408c|M.abscessus_ATCC_199 SDVVANGSTQLLQGEVPAVTTVEDAKGNKIAYLYTQRRFEVSADEIADTM
*:******: *::*:** *:*: *::** **:**.***:**.:::**:**
Mflv_1365|M.gilvum_PYR-GCK KLAIVSIEDKRFADHNGVDWQGTLTGLSGYLSGNLDTRGGSTIEQQYVKN
Mvan_5442|M.vanbaalenii_PYR-1 KLAIVSIEDKRFADHNGVDWQGTLTGLSGYLSGNLDTRGGSTIEQQYVKN
MSMEG_6201|M.smegmatis_MC2_155 KLAIVSIEDKRFAEHNGVDWQGTLTGLSGYLSGNPDTRGGSTIEQQYVKN
TH_2122|M.thermoresistible__bu KLAIVAIEDKRFAEHNGVDWQGTLTGLTGYLRGDSDTRGGSTLEQQYVKN
MMAR_5171|M.marinum_M KLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQYIKN
MUL_4257|M.ulcerans_Agy99 KLAIVSIEDKRFAEHNGVDWKGTLTGLAGYASGDLDTRGGSTIEQQYIKN
Mb3707|M.bovis_AF2122/97 KLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKN
Rv3682|M.tuberculosis_H37Rv KLAIVSIEDKRFADHSGVDWKGTLTGLAGYASGDLDTRGGSTLEQQYVKN
MAV_0446|M.avium_104 KLAIVSIEDKRFADHNGVDWKGTLTGLAGYARGDVDTRGGSTIEQQYIKN
MLBr_02308|M.leprae_Br4923 KLAIVSIEDKRFTDHNGVDWPGTLTGLAGYASGDVDTRGGSTIEQQYVKN
MAB_0408c|M.abscessus_ATCC_199 KLALLSIEDKRFTSHNGVDWKGTLGGLAGYASGDEDTRGGSTIEQQYVKN
***:::******:.*.**** *** **:** *: *******:****:**
Mflv_1365|M.gilvum_PYR-GCK YQLLVIAQTDAEKRAAIETTPARKLREIRMALTLDKTFTKPEILTRYLNL
Mvan_5442|M.vanbaalenii_PYR-1 YQLLVIAQTDAEKRAAIETTPARKLREIRMALTLDKTFTKPEILTRYLNL
MSMEG_6201|M.smegmatis_MC2_155 YQLLVVAQTDAERRAAIETTPARKLREIRMALTLDKTFTKPEILTRYLNL
TH_2122|M.thermoresistible__bu YQLLVVAQTDAEKRAAIETTPARKLREIRMALTLDKTLTKPEILTRYLNL
MMAR_5171|M.marinum_M YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL
MUL_4257|M.ulcerans_Agy99 YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL
Mb3707|M.bovis_AF2122/97 YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNL
Rv3682|M.tuberculosis_H37Rv YQLLVTAQTDAEKRAAVETTPARKLREIRMALTLDKTFTKSEILTRYLNL
MAV_0446|M.avium_104 YQLLVTAKTDAEKRAAVETTPARKLREIRMALTLDKTFTKPEILTRYLNL
MLBr_02308|M.leprae_Br4923 YQLLVTAQTDAEKRAAVETTPARKLREIRIALTLDKTFTKPEILTRYLNL
MAB_0408c|M.abscessus_ATCC_199 YQLLVVAKTDAERKAAIETTPARKLREIRMALRLDQTFTKQEILTRYLNL
***** *:****::**:************:** **:*:** *********
Mflv_1365|M.gilvum_PYR-GCK VSFGNNAFGVQDAAQTYFGINATDLNWQQAALLAGMVQSTSTLNPYTNPD
Mvan_5442|M.vanbaalenii_PYR-1 VSFGNNAFGVQDAAQTYFGVNASELNWQQAALLAGMVQSTSTLNPYTNPD
MSMEG_6201|M.smegmatis_MC2_155 VSFGNGAYGIQDAAQTYFGVNASELNWQQAALLAGMVQSTSALNPYTNPD
TH_2122|M.thermoresistible__bu VSFGNGAYGIQDAAQTYFGINASELDWHQAALLAGLVQSTTALNPYTNPD
MMAR_5171|M.marinum_M VSFGNNSFGVQDAAQTYFGINASELNWQQSALLAGMVQSTSTLNPYTNPD
MUL_4257|M.ulcerans_Agy99 VSFGNNSFGVQDAAQTYFGINASELNWQQSALLAGMVQSTSTLNPYTNPD
Mb3707|M.bovis_AF2122/97 VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPD
Rv3682|M.tuberculosis_H37Rv VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSTLNPYTNPD
MAV_0446|M.avium_104 VSFGNNSFGVQDAAQTYFGINASDLNWQQAALLAGMVQSTSALNPYTNPE
MLBr_02308|M.leprae_Br4923 VSFGNNSFGVQDAAQTYFGVNASDLNWQQAALLAGMVQSTSTLNPYTNPE
MAB_0408c|M.abscessus_ATCC_199 VSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGLNPYVNPE
*****.::*:*********::*.:*:*:*:*****:****: ****.**:
Mflv_1365|M.gilvum_PYR-GCK GALARRNVVLDTMIENLPEYADELRAARQEPLGVLPQPKELPRGCIAAGD
Mvan_5442|M.vanbaalenii_PYR-1 GALARRNVVLDTMIENLPEHADELRTAKQQPLGILPQPKELPRGCIAAGD
MSMEG_6201|M.smegmatis_MC2_155 GALARRNLVLDTMIQNIPQEAEALRAAKEQPLGILPQPNELPRGCIAAGD
TH_2122|M.thermoresistible__bu GALARRNLVLDTMIDQLPQEAEALRAAKEQPLGILPRPNELPRGCIAAGD
MMAR_5171|M.marinum_M GALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQPNELPRGCIAAGD
MUL_4257|M.ulcerans_Agy99 GALARRNLVLDTMIQNIPSEADALRAAKAEPLGILPQPNELPRGCIAAGD
Mb3707|M.bovis_AF2122/97 GALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGD
Rv3682|M.tuberculosis_H37Rv GALARRNVVLDTMIENLPGEAEALRAAKAEPLGVLPQPNELPRGCIAAGD
MAV_0446|M.avium_104 GALARRNLVLDTMIENIPQEADALRAAKAAPLGILPQPNELPRGCIAAGD
MLBr_02308|M.leprae_Br4923 GALARRNLVLDTMIENLPQDAEALRAAKTEPLGILPRPNELPRGCIAAGD
MAB_0408c|M.abscessus_ATCC_199 RALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGD
******:****** : * * :*: ***:**:*:***********
Mflv_1365|M.gilvum_PYR-GCK RAFFCDYALDYLARAGISKDQVAKGGYMIKTTLDPDVQASVKNAITQYAS
Mvan_5442|M.vanbaalenii_PYR-1 RAFFCDYALDYLARAGISKDQVAKGGYLIKTTLEPDVQASVKNAINEFAS
MSMEG_6201|M.smegmatis_MC2_155 RAFFCDYVLEYLARAGISKEQVAKGGYLIKTTLDPDVQSSVKSAIDSIAA
TH_2122|M.thermoresistible__bu RAFFCDYVLEYLARAGISKEQVAKGGYLIKTTLDPEVQRAVKSAIDQYAR
MMAR_5171|M.marinum_M RAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFAS
MUL_4257|M.ulcerans_Agy99 RAFFCDYVQEYLSRAGISKEQLARGGYLIRTTLDPDVQVPVKAAIDKFAS
Mb3707|M.bovis_AF2122/97 RAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYAS
Rv3682|M.tuberculosis_H37Rv RAFFCDYVQEYLSRAGISKEQVATGGYLIRTTLDPEVQAPVKAAIDKYAS
MAV_0446|M.avium_104 RAYFCDYVQEYLSRAGISKEQVARGGYLIKTTLDPDVQIPVKAAIDKFAS
MLBr_02308|M.leprae_Br4923 RAFFCDYVQEYLSHAGISKDRLAKGGYLIRTTLDPNVQAPVKAAIDKFAS
MAB_0408c|M.abscessus_ATCC_199 RAFFCDYVLDYLAKSGISKDQVMKGGYLIRTTLDPDVQNSVKQAVSHVAD
**:****. :**:::****::: ***:*:***:*:** .** *: *
Mflv_1365|M.gilvum_PYR-GCK PDLPGVASVMSVVKPGKDSHPVLAMASNRTYGLNLDAGETMQPQPFSLVG
Mvan_5442|M.vanbaalenii_PYR-1 PDLPGVASVMSVIRPGKDSHPVLAMASNRTYGLNLDAGETMQPQPFSLVG
MSMEG_6201|M.smegmatis_MC2_155 PDTPGVASVMSVIKPGKESHPVLAMASNRTYGLDTERGETMQPQPFSLVG
TH_2122|M.thermoresistible__bu PDANGVASVMSVIRPGKESHPVLAMASSRHYGLNSEAGETMQPQPFSLVG
MMAR_5171|M.marinum_M PTLPGISSVMSVIKPGKESHQVLAMASNRKYGLDINAGETMRPQPFSLVG
MUL_4257|M.ulcerans_Agy99 PTLPGISSVMSVIKPGKESHQVLAMASNRAYGLDINAGETMRPQPFSLVG
Mb3707|M.bovis_AF2122/97 PNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVG
Rv3682|M.tuberculosis_H37Rv PNLAGISSVMSVIKPGKDAHKVLAMASNRKYGLDLEAGETMRPQPFSLVG
MAV_0446|M.avium_104 PTLPGISSVMSVIQPGKTSHKVMAMASNRTYGLDVDAGQTMRPQPFSLVG
MLBr_02308|M.leprae_Br4923 PNLAGISSVMSVITPGKDAHRVIAMGSNRRYGLDTEAGETMRPQTFSLVG
MAB_0408c|M.abscessus_ATCC_199 PGLNGIANVMSVIKPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVG
* *::.****: **: :* ::**.*.* ***: : :**:**.*****
Mflv_1365|M.gilvum_PYR-GCK NGAGSVFKIFTTAAAMEMGMGINAQLDSPSRFEAKGLGSG-GARGCPPAT
Mvan_5442|M.vanbaalenii_PYR-1 NGAGSVFKIFTTAAAMEMGMGINAQLDSPSRFEAKGLGSG-GARGCPPAT
MSMEG_6201|M.smegmatis_MC2_155 NGAGSVFKIFTVAAAMEMGMGINTQLPVPARFEAKGLGSG-GARGCPPAT
TH_2122|M.thermoresistible__bu HGAGSVFKIFTTAAAMEMGMGINTQLEAPAFFQAKGLGSS-DTPGCPAAT
MMAR_5171|M.marinum_M DGAGSIFKIFTTAAALDMGMGINAQLDVPGRFQGKGLGSG-GAKGCPKDT
MUL_4257|M.ulcerans_Agy99 DGAGSIFKIFTTAAALDMGMGISAQLDVPGRFQGKGLGSG-GAKGCPKDT
Mb3707|M.bovis_AF2122/97 DGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSG-GAKGCPKET
Rv3682|M.tuberculosis_H37Rv DGAGSIFKIFTTAAALDMGMGINAQLDVPPRFQAKGLGSG-GAKGCPKET
MAV_0446|M.avium_104 DGAGSVFKIFTTAAALDMGMGINATLEVPGRFQAKGMGSG-GAKGCPKDT
MLBr_02308|M.leprae_Br4923 DGAGSVFKIFTTAAALDMGMGINAKLEVPSRFQAKGMGSG-GAKGCPKET
MAB_0408c|M.abscessus_ATCC_199 DGAGSIFKIFTVAAAMDMGMGINTVLDVPPTFAAKGLGSSDGSKGCPKDN
.****:*****.***::*****.: * * * .**:**. .: *** .
Mflv_1365|M.gilvum_PYR-GCK WCVQNAGNYRGTMSVTDALATSPNTAFAKLIAQVGVQRTVDMAVRLGLRS
Mvan_5442|M.vanbaalenii_PYR-1 WCVQNAGNYRGTMNVTDALATSPNTAFAKLIAQVGVQRTVDMAVKLGLRS
MSMEG_6201|M.smegmatis_MC2_155 WCVQNAGGYRGSMSVTDALATSPNTAFAKLISQIGVQRAVDMAVRLGLRS
TH_2122|M.thermoresistible__bu WCVRNAGSYRGSMNVTDALATSPNTAFAKLISQIGVPRTVDMAVRLGLRS
MMAR_5171|M.marinum_M WCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGLRS
MUL_4257|M.ulcerans_Agy99 WCVINAGNYRGSMSVTDALATSPNTAFAKLISQVGVSRTVDMAIKLGLRS
Mb3707|M.bovis_AF2122/97 WCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRS
Rv3682|M.tuberculosis_H37Rv WCVVNAGNYRGSMNVTDALATSPNTAFAKLISQVGVGRAVDMAIKLGLRS
MAV_0446|M.avium_104 WCVVNAGNYKGSMNVTEALATSPNTAFAKLIQQVGVTRTVDMAIKLGLRS
MLBr_02308|M.leprae_Br4923 WCVINAGNYRGSMNVTDALATSPNTAFAKLIQQVGVARTVDMAIKLGLRS
MAB_0408c|M.abscessus_ATCC_199 WCVKNVGNYRSPMSVTDALATSPNTAFAKLIQSIGVSKAVDMAVKLGMRS
*** *.*.*:..*.**:************** .:** ::****::**:**
Mflv_1365|M.gilvum_PYR-GCK YALPGTARDYDPESNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
Mvan_5442|M.vanbaalenii_PYR-1 YALPGTARDYDPESNESLADFVKRQNLGSFTLGPIEVNALELSNVAATLA
MSMEG_6201|M.smegmatis_MC2_155 YAQPGTARDYDPESSESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
TH_2122|M.thermoresistible__bu YAQPGTARDYDPNSDESIADWVKRQNIGSFTLGPIEVNALELSNVAATLA
MMAR_5171|M.marinum_M YANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
MUL_4257|M.ulcerans_Agy99 YANPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
Mb3707|M.bovis_AF2122/97 YANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLA
Rv3682|M.tuberculosis_H37Rv YANPGTARDYNPDSNESLADFVKRQNLGSFTLGPIELNALELSNVAATLA
MAV_0446|M.avium_104 YADPGTARDYNPDSNESLADFVKRQNIGSFTLGPIEVNALELSNVAATLA
MLBr_02308|M.leprae_Br4923 YTTPGTARDYNPDSNESLADFVKRQNIGSFTLGPIKVNALELSNVAATLA
MAB_0408c|M.abscessus_ATCC_199 YAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELSNVAATLA
*: ****: *:*:..**:*:::*: *:********::*.***********
Mflv_1365|M.gilvum_PYR-GCK SGGMWCPPNPIAEVYDRYGEPVSVTTETCEQAVPEGLANTLANAMSKDDT
Mvan_5442|M.vanbaalenii_PYR-1 SGGMWCPPNPIAEVRDRYGELVSVTTETCEQVVPEGLANTLAVAMSKDDT
MSMEG_6201|M.smegmatis_MC2_155 SGGTWCPPNPIAQVVDRNGNEVAVTTETCEQVVPEGLANTLANAMSKDDT
TH_2122|M.thermoresistible__bu SGGVWCPPNPIDKVYDRHGNEVSVTTETCEQVVPEGLANTLANAMSEDDR
MMAR_5171|M.marinum_M SGGVWCPPNPVDKLIDRNGNEVAVTTETCDQVVPEGLANTLANAMSKDAV
MUL_4257|M.ulcerans_Agy99 SGGVWCPPNPVDKLIDRNGNEVAVTTETCDQVVPEGLANTLANAMSKDAV
Mb3707|M.bovis_AF2122/97 SGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAV
Rv3682|M.tuberculosis_H37Rv SGGVWCPPNPIDQLIDRNGNEVAVTTETCDQVVPAGLANTLANAMSKDAV
MAV_0446|M.avium_104 SGGTWCPPNPIDKLIDRKGNEVAVTTETCDQVVPEGLANTMANAMSKDAV
MLBr_02308|M.leprae_Br4923 SGGMWCPPNPIDKLFDRNGNEVAVTVETCDRVVPEGLANTLANAMSKDTK
MAB_0408c|M.abscessus_ATCC_199 SGGKWCPPNPIDKVFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQ
*** ******: :: ** *: *..*.*:*::.** *****:* *:*:*
Mflv_1365|M.gilvum_PYR-GCK GAGTAAGAAGSVGWNLPMSGKTGTTEANRSSAFLGFTNRYAAASYIYDDS
Mvan_5442|M.vanbaalenii_PYR-1 GAGTAAGAAGSTGWSLPMSGKTGTTESNRSSAFLGFTNQYAAASYIYDDS
MSMEG_6201|M.smegmatis_MC2_155 GSGTAAASAGSVGWNLPMSGKTGTTEDNRSSAFLGFTNQYAAANYIYDDS
TH_2122|M.thermoresistible__bu GAGTAAGAAASVGWDLPMSGKTGTTESNRSSAFLGFTNQLAAANYIYDDS
MMAR_5171|M.marinum_M GGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
MUL_4257|M.ulcerans_Agy99 GGGTASGSAGAAGWSLPVSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
Mb3707|M.bovis_AF2122/97 GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
Rv3682|M.tuberculosis_H37Rv GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSAGFVGFTNRYAAANYIYDDS
MAV_0446|M.avium_104 GGGTAAGSAGAAGWDLPMSGKTGTTEAHRSSGFVGFTNHYAAANYIYDDS
MLBr_02308|M.leprae_Br4923 GSGTAAGSAGAAGWDLPMSGKTGTTEAHRSSGFVGFTNHYAAANYIYDDS
MAB_0408c|M.abscessus_ATCC_199 PGGTAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGASYIYDDS
.***:.:*.:.**.**:*.****** :**:.*:*:**. *.*.******
Mflv_1365|M.gilvum_PYR-GCK TAPTELCSFPLRQCGSGNLFGGNEPARTWFSAMQPIATAFGDVTLPPTDP
Mvan_5442|M.vanbaalenii_PYR-1 TAPTELCSFPLRQCGSGNLFGGNEPARTWFTAMTPIATAFGDVTLPPTDP
MSMEG_6201|M.smegmatis_MC2_155 PNPSELCSFPLRQCGSGNLFGGNEPARTWFTAMKPIAESFGPVALPPTDP
TH_2122|M.thermoresistible__bu NSPGELCSFPLRRCGSGDLFGGNEPARTWFAAMKPIAEKFGPVALPPTDP
MMAR_5171|M.marinum_M TNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDP
MUL_4257|M.ulcerans_Agy99 TNPTDLCSGPLRHCGNGDLYGGNEPARTWFTALKPIATDFGEVQLPPTDP
Mb3707|M.bovis_AF2122/97 SSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDP
Rv3682|M.tuberculosis_H37Rv SSPTDLCSGPLRHCGSGDLYGGNEPSRTWFAAMKPIANNFGEVQLPPTDP
MAV_0446|M.avium_104 PNPTDLCSAPLRHCGEGDLYGGNEPARTWFTAMKPIATNFGPVQLPPTDP
MLBr_02308|M.leprae_Br4923 TSPTNLCSGPLRHCSNGDLYGGNEPARTWFTAMKPIATKFGEVRLPPTDP
MAB_0408c|M.abscessus_ATCC_199 TTPGDLCSFPLRKCGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEP
* :*** ***:*..*:*:*****:*:** *: *** :* . ****:*
Mflv_1365|M.gilvum_PYR-GCK RYVEGAPGSKVPSVAGMDQDTARARLREAGFQVADQATPVNSSSRYGTVV
Mvan_5442|M.vanbaalenii_PYR-1 RYVDGAPGSKVPSVAGMNQDTARQRLREAGFQVADQPTPVNSTAPYGAVV
MSMEG_6201|M.smegmatis_MC2_155 RYVDGGPGSRVPSVSGLTEEAARQRLKEAGFQVADQASYVNSGARSGTVV
TH_2122|M.thermoresistible__bu RYVDGGPGSRVPSVSGLSEEAARQRLRDAGFQVADGVATVNSSARRGTVV
MMAR_5171|M.marinum_M RYVDGAPGSRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEVV
MUL_4257|M.ulcerans_Agy99 RYVDGAPGSRVPSVAGLDVDQARQRLKDAGFQVADQPNAVNSSARYGEAV
Mb3707|M.bovis_AF2122/97 RYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVV
Rv3682|M.tuberculosis_H37Rv RYVDGAPGSRVPSVAGLDVDAARQRLKDAGFQVADQTNSVNSSAKYGEVV
MAV_0446|M.avium_104 RYVDGAPGSRVPSVAGLDIDAARQRIKEAGFQVADQNNFVNSSAKQGEVV
MLBr_02308|M.leprae_Br4923 RYVDGSPGSQVPSVTGLDLDAARQRLKGAGFQVADQPTLINSTAKLGAVV
MAB_0408c|M.abscessus_ATCC_199 RYVEGGPGSKVPSINGLREPEARDVLKKAGFRVADQASSVNSTAPFNEVV
***:*.***:***: *: ** :: ***:*** :** : . .*
Mflv_1365|M.gilvum_PYR-GCK GTAPSGQTVPGSIVTIQISNGIAPAPPPPPAG--APPPGGPP--------
Mvan_5442|M.vanbaalenii_PYR-1 GTSPTGQTVPGSIITIQISNGIAPPPPPPPPG--APP-GLPP--------
MSMEG_6201|M.smegmatis_MC2_155 GTTPSGQTIPGSIITIQLSNGIPPPPPPPVN--IPLPGGP----------
TH_2122|M.thermoresistible__bu GTNPSGQTIPXXYPTQFLRADLDALGVIPADKLLEVPDGTRILIAGAVTH
MMAR_5171|M.marinum_M GTSPSGQTIPGSIITIQISNGIPPAPPPPP---EGEPPPP----------
MUL_4257|M.ulcerans_Agy99 GTSPSGQTIPGSIITIQISNGIPPAPPPPP---EGEPPPP----------
Mb3707|M.bovis_AF2122/97 GTSPSGQTIPGSIVTIQISNGIPPAPPPPPLPEDGGPPPP----------
Rv3682|M.tuberculosis_H37Rv GTSPSGQTIPGSIVTIQISNGIPPAPPPPPLPEDGGPPPP----------
MAV_0446|M.avium_104 GTTPSGATIPGSIITIQVSNGIPPAPPPPP----EGAPPP----------
MLBr_02308|M.leprae_Br4923 GTTPSGQTIPGSIITIQTSSGIPPAPPPPP---EGGPPMPPS--------
MAB_0408c|M.abscessus_ATCC_199 GTSPSGTTIPGSVITILMSNGIPPAPPPLVIPGIPGAPPG----------
** *:* *:* * .: . .
Mflv_1365|M.gilvum_PYR-GCK ---PPAGETVIQIPGLPPIT--VPVLGPPP--------PPPPPPG-----
Mvan_5442|M.vanbaalenii_PYR-1 ---PPVGQTVIQIPGLPPIT--VPVLGPPP--------PPPPPPG-----
MSMEG_6201|M.smegmatis_MC2_155 ---PEIGQTVVEIPGLPPIT--VPVLGPP---------PPPPPP------
TH_2122|M.thermoresistible__bu RQRPATAQGVTFLN-LEDETGMVNVLCSPGVWARHRRLAQTAPALLVRGI
MMAR_5171|M.marinum_M -----VGSQVVEIPGLPPIT--IPLLAPPP-------P------------
MUL_4257|M.ulcerans_Agy99 -----VGSQVVEIPGLPPIT--IPLLAPPP-------P------------
Mb3707|M.bovis_AF2122/97 -----VGSQVVEIPGLPPIT--IPLLAPPP-------PAP--PP------
Rv3682|M.tuberculosis_H37Rv -----VGSQVVEIPGLPPIT--IPLLAPPP-------PAP--PP------
MAV_0446|M.avium_104 -----VGSQVVEIPGLPPIT--IPLLAPPP-------PAPGQPPP-----
MLBr_02308|M.leprae_Br4923 -----VGSQVIEIPGLPPIT--IPLLAPP---------------------
MAB_0408c|M.abscessus_ATCC_199 ----EMTTTIVNIPGLPPIT--VPVLAPPP--------------------
: : * * : :* .*
Mflv_1365|M.gilvum_PYR-GCK ------------------------------
Mvan_5442|M.vanbaalenii_PYR-1 ------------------------------
MSMEG_6201|M.smegmatis_MC2_155 ------------------------------
TH_2122|M.thermoresistible__bu VQNATGAVTVVADRMRRLELRVGSRSRDFR
MMAR_5171|M.marinum_M ------------------------------
MUL_4257|M.ulcerans_Agy99 ------------------------------
Mb3707|M.bovis_AF2122/97 ------------------------------
Rv3682|M.tuberculosis_H37Rv ------------------------------
MAV_0446|M.avium_104 ------------------------------
MLBr_02308|M.leprae_Br4923 ------------------------------
MAB_0408c|M.abscessus_ATCC_199 ------------------------------