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RELVTPGRTAVVTQECQGAVIGPDAGLRALADEAQRVALPNIKRLLPAARAASVHVVHCLVQRRPDGLGS NRNAKIFAIGRNDVAIAPGTPGAALLPELGPEAGDLVLTRWHGLGPMGGTDLDAVLRNLGVTTIVAVGVS VNVAITNLVMDAVNAGYHVVLPRDAVAGVPTDYADAVIDNTLSLLATVTSTDQLLQIWQP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2243 | - | - | 100% (201) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4379 | - | 5e-11 | 28.75% (160) | isochorismatase hydrolase |
| M. smegmatis MC2 155 | MSMEG_4126 | - | 2e-07 | 29.37% (126) | hydrolase, isochorismatase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4334 | - | 3e-78 | 72.59% (197) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3431c | - | 6e-13 | 27.67% (206) | isochorismatase hydrolase |
| M. marinum M | MMAR_2657 | - | 4e-10 | 28.22% (163) | isochorismatase family protein |
| M. avium 104 | MAV_1602 | - | 2e-83 | 75.12% (201) | isochorismatase family protein |
| M. thermoresistible (build 8) | TH_1628 | - | 9e-84 | 75.25% (198) | isochorismatase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2011 | - | 8e-83 | 77.27% (198) | isochorismatase hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4334|M.gilvum_PYR-GCK ---------MRIPLAELVAPGHTAVVTQECQEAVVG--TNAGLAALADAA
Mvan_2011|M.vanbaalenii_PYR-1 ---------MRIPLAELVAPGHTAVVTQEYQGAVVG--PHAGLAALADEA
MAV_1602|M.avium_104 ----------MTDLAELVAPAHTAVITQEVQGAVVG--PDAGLGALAAEA
TH_1628|M.thermoresistible__bu ---------VTPPLAELIRPAHTAIVTQELQGAVVG--PDAGLAALAHEA
MSMEG_2243|M.smegmatis_MC2_155 -------------MRELVTPGRTAVVTQECQGAVIG--PDAGLRALADEA
MAB_3431c|M.abscessus_ATCC_199 MTGQVDAQPYPWPFDGPVDPGRTAVLCIDWQVDFCGRGGYVDTMGYDLSL
MMAR_2657|M.marinum_M -------------------------------------------MGYDLSL
.
Mflv_4334|M.gilvum_PYR-GCK RGEALPNISRLLPVARRAGVDVVHCLVQRRADG--RGANHNAKLFTVGA-
Mvan_2011|M.vanbaalenii_PYR-1 RREALPNIARLLPVARAAGASVVHCLVQRRADG--RGANHNAKIFAIGA-
MAV_1602|M.avium_104 RRVALPNIVRLLPPARAAGVRIVHCLVQRRPDG--LGSNHNAKIFALGRR
TH_1628|M.thermoresistible__bu RREALPNIARLLPAARAAGVRVVHCLVQRRPDG--LGSNHNARLFAVGR-
MSMEG_2243|M.smegmatis_MC2_155 QRVALPNIKRLLPAARAASVHVVHCLVQRRPDG--LGSNRNAKIFAIGR-
MAB_3431c|M.abscessus_ATCC_199 TRAGLEPTARVLAAARAVGMTIIHTREGHRPDLSDLPANKRWRSARIGAE
MMAR_2657|M.marinum_M VRAPLGPAQTVLEAARKLGLLIVHTREGHRPDLSDLPANKRWRSARIGAE
* :* ** . ::* :*.* :*:. : :*
Mflv_4334|M.gilvum_PYR-GCK ------SGVDITPDSPGTQLVPEIDVQPSDLVLRRWHGLGPMGGTDLDAI
Mvan_2011|M.vanbaalenii_PYR-1 ------TGVDITPGSPGTQLVPEIDPQPTDLVLYRWHGLGPMGGTDLDAV
MAV_1602|M.avium_104 S---GQGRVDISPGTPGATLLPELGPAPSDLVLSRWHGVGPMGGTDLDAV
TH_1628|M.thermoresistible__bu ------GSVDITPGSAGATLLPEFGPAPSDVVLYRWHGVGPMGGTDLDAI
MSMEG_2243|M.smegmatis_MC2_155 ------NDVAIAPGTPGAALLPELGPEAGDLVLTRWHGLGPMGGTDLDAV
MAB_3431c|M.abscessus_ATCC_199 IGVAGPCGRILVKGEPGWEIVPEVAPLPGEPIIDKP-GKGAFYATDLDLV
MMAR_2657|M.marinum_M IGVAGPCGRVLTRGEPGWEIIPEMEPLPGEMVVDKL-GKGSFYATDLELI
: . .* ::**. . : :: : * *.: .***: :
Mflv_4334|M.gilvum_PYR-GCK LRNLGVTTIVAVGVSVNVAILNLVMDAVNAGYRVVLPRDGVAGIP-AEYA
Mvan_2011|M.vanbaalenii_PYR-1 LRNLDVRTIVAVGVSVNVAITNLVMDAVNVGYRVVVPRDAVAGIP-ADYA
MAV_1602|M.avium_104 LRNLGVSTLVVVGVSLNIAIPNVVMDAVNAAYRVVVPRDAVAGVP-AEYG
TH_1628|M.thermoresistible__bu LRNLGVSTIVAVGVSLNVAIPNLVMDAVNAAYRVVLPRDAVAGVP-ADYG
MSMEG_2243|M.smegmatis_MC2_155 LRNLGVTTIVAVGVSVNVAITNLVMDAVNAGYHVVLPRDAVAGVP-TDYA
MAB_3431c|M.abscessus_ATCC_199 LRTRGIRYIVLTGITTDVCVHTTMREANDRGFECLILSDCTGATDAGNHA
MMAR_2657|M.marinum_M LTTRRITHLIFTGIATDVCVHTTMREANDRGYECLLLSDCTGATDYANHL
* . : :: .*:: ::.: . : :* : .:. :: * ... ::
Mflv_4334|M.gilvum_PYR-GCK TAVIDNTLS--LLATLTITDDLISAWAATC----
Mvan_2011|M.vanbaalenii_PYR-1 AAVIDNTLS--LLATVTTTDELLDAWR-------
MAV_1602|M.avium_104 EAVIANTLS--LLATITTTDELLRAWSRP-----
TH_1628|M.thermoresistible__bu NAIIDNTLA--LLATVSTTDDLLDTWKQEAG---
MSMEG_2243|M.smegmatis_MC2_155 DAVIDNTLS--LLATVTSTDQLLQIWQP------
MAB_3431c|M.abscessus_ATCC_199 AALKMVTMQGGVFGAVADSNQLLGAL--------
MMAR_2657|M.marinum_M AALKMITMQGGVFGAHATNGALLEAFNKVRDRRG
*: *: ::.: : .. *: