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LLQNLGDMLDDLADDYLMRVDSGARFYDNVPSEEDLRDAARLAFRYLLDTLLERPMSRRLIEFPAAVGSL RATQGIALENLTAAVRTDFLVAWSALLRLAGEDDMAILALHVDVLWKTVDDFTIQVQRGYLDQRLAMART SALEQQHTLSDLFCREPAPTTVRRAAQILGLEETATYWIIGTPSEEAGRSVARRLLNKHLTPFEYIDRGI ALILVAADGRWADDEAVVADVMSGLDGAVAPRSVPLADVHRAAATVRMLVDLGKSGATTLLRSWVHLSMA QLSEVIDDLRGYVLDPLRKVHDRELIVETIQTFADNGSVADTASVLYCHRNTVMNRIRRFEEATGISLRS PRSLAMVQLCLLPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3997 | - | - | 100% (364) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3552 | - | 1e-47 | 32.56% (387) | hypothetical protein MSMEG_3552 |
| M. smegmatis MC2 155 | MSMEG_5120 | - | 3e-06 | 29.58% (142) | hypothetical protein MSMEG_5120 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0801 | - | 1e-06 | 34.51% (113) | transcriptional regulator, CdaR |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0762 | - | 3e-13 | 26.50% (317) | hypothetical protein MAB_0762 |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4933 | - | 2e-09 | 27.36% (296) | hypothetical protein MAV_4933 |
| M. thermoresistible (build 8) | TH_3478 | - | 2e-07 | 25.20% (377) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1854 | - | 4e-06 | 29.30% (157) | purine catabolism PurC domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0762|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3478|M.thermoresistible__bu --------------------------------------------------
MAV_4933|M.avium_104 ------------------------------------MKDFRAPVNGVDGD
Mvan_1854|M.vanbaalenii_PYR-1 MITARSLCQDENLGLTLVAGAQAADRPIAWAHAIELADPTPYLAGGELVM
MSMEG_3997|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0801|M.gilvum_PYR-GCK --------------MSEDRAESAAPTLRDLLEAAQLSLSGPDPADRNLDR
MAB_0762|M.abscessus_ATCC_1997 ------------------------MGEQLLARVDELCAEQCRIIRERVA-
TH_3478|M.thermoresistible__bu ----------------------------MLDELEDIAAQVTAIIRAELP-
MAV_4933|M.avium_104 SASALVAVPKSQGAQTIRPDSVSRLVGALLDDHAAVVGRVRSVIRSRLP-
Mvan_1854|M.vanbaalenii_PYR-1 TTGINIGADAAAQADYVARLAAAGTAALAVDTGTTLTAVPAGVLAAGDE-
MSMEG_3997|M.smegmatis_MC2_155 ------------------------MLQNLGDMLDDLADDYLMRVDSGAR-
Mflv_0801|M.gilvum_PYR-GCK EVSWVHTTEMRDPSRYLRGGELVCTVGISLHSAEDCSTFVDALAGAGAAG
MAB_0762|M.abscessus_ATCC_1997 --AYRDPVLVTDEDLFAAGRDQMVYVLAAMG-SGAPDTSA-AARVGRLRA
TH_3478|M.thermoresistible__bu --AYAAIPLDDHRAAVQDQLSVILTGLREMRGPGPADLIT-AERLGRRRA
MAV_4933|M.avium_104 --VYRSVADEALEAELEWVLRSAVGGREALH---EPQIAG-LAAIGEARA
Mvan_1854|M.vanbaalenii_PYR-1 --HGVPVLRVPASTPFIAIARVVIDAVKADQLESVQRVVDQQEVLARATL
MSMEG_3997|M.smegmatis_MC2_155 --FYDNVPSEEDLRDAARLAFRYLLDTLLER-PMSRRLIEFPAAVGSLRA
Mflv_0801|M.gilvum_PYR-GCK VCFGVGDGHDDVPAALLDACRRAGLPVLVAPPSVPFSVISRFVAESRLGT
.
MAB_0762|M.abscessus_ATCC_1997 EQGVP-LADVMSAYRAGGQFLWDALSQAIDAAGLSRQELRAAASQAWQNH
TH_3478|M.thermoresistible__bu EQGID-ISALMRAYELPLQELWQRYAG-LVCDGKQAQELIALAPSLLRWL
MAV_4933|M.avium_104 RDGVP-VDDMLRAWRIGVEVVVECAREAARRLGVDDARVLELVQSALAWS
Mvan_1854|M.vanbaalenii_PYR-1 RGGIPGVVGALAECLSAVVVAVSTDGRDLAAGGTADPQLISALSEAVGQA
MSMEG_3997|M.smegmatis_MC2_155 TQGIA-LENLTAAVRTDFLVAWSALLR---LAGEDDMAILALHVDVLWKT
Mflv_0801|M.gilvum_PYR-GCK EIAVARATNALVPELLLSLRRHDSPRRLLDAAGQVLGCYFLLEPEGAAKG
.: . * .
MAB_0762|M.abscessus_ATCC_1997 DRYTDAMAEGYRDVVVEQLIQRDQERAALVSGLIDGRFPAGITAWN----
TH_3478|M.thermoresistible__bu HQLGGAAATGHQIVTTSQLANEVRLQAQLLDLITAD--PAGAQTLV----
MAV_4933|M.avium_104 DIAMATSAKAHRRTERALALEAEESDAEFVRGALMGSLPAAELRMH----
Mvan_1854|M.vanbaalenii_PYR-1 RNRGAAVIPDGDALLTIQRLRAAQAVRGYLVVRSAGPLSDSGRLLVSHAV
MSMEG_3997|M.smegmatis_MC2_155 VDDFTIQVQRGYLDQRLAMARTSALEQQHTLSDLFCREPAPTTVRR----
Mflv_0801|M.gilvum_PYR-GCK DEAAVTVPVPG--LGALVWMGRGDRPEPALLDLIARFVRAAQGERD---I
MAB_0762|M.abscessus_ATCC_1997 AAHQLGLPESGAFVVVAIESGPLDYRTLRSAEKALRDQGFASAWRVDPDM
TH_3478|M.thermoresistible__bu LAGRLGLDTGGTFQAVGFTP-SVDPHRLERVIVRLRIHAGPVVAGVHDGM
MAV_4933|M.avium_104 AELR-GLDPGAEYVAVRARLGGDGPHLRLEQSLGFQDPAHSRRG------
Mvan_1854|M.vanbaalenii_PYR-1 SLISIALEKPARVQDAEQRLRSAVTRELLGGRGAVDDGLLRYFGFTPDGD
MSMEG_3997|M.smegmatis_MC2_155 AAQILGLEETATYWIIGTPSEEAGRSVARR----LLNKHLTPFEYIDRGI
Mflv_0801|M.gilvum_PYR-GCK EAALTRERVGQLLSLVERRMLLPDALSQLVQWPGFAGEIACSAWPAGAGA
.
MAB_0762|M.abscessus_ATCC_1997 QVGIVAL---PTPSRLEELGETLRNLGVRRIGVS--------PVYDGYPP
TH_3478|M.thermoresistible__bu FVVLQQH---DRTGVVTQLCRPHAAGGVFGIGE---------PRYG-LQG
MAV_4933|M.avium_104 LCALLDG---DLAGFLIEP--PRDVEGVVGFGP---------PRPLTRLS
Mvan_1854|M.vanbaalenii_PYR-1 VVVSVLHGIGPVLAAEEELSRPLADTGPYLMAATGTEIVIVLPADGSRAR
MSMEG_3997|M.smegmatis_MC2_155 ALILVAA---DGRWADDEAVVADVMSGLDGAVAP-----------RSVPL
Mflv_0801|M.gilvum_PYR-GCK LLSISFPG--ALIGDAPDLCMMLTAGAVEMPDDLALPTGHSAPVTLADLG
: .
MAB_0762|M.abscessus_ATCC_1997 PGPPLNYAKAALLAATEDDPVVAFDANPYAVAAITDPQTMARYRDLVLGS
TH_3478|M.thermoresistible__bu AALSIGDARRAAGLAAVLGHDVVFSRHWLLASVLASADHLD-----HLGR
MAV_4933|M.avium_104 ESYRMAARALVTAEACGLRGAYDIAALGLRTAVAIDADVGELLRKRYLEP
Mvan_1854|M.vanbaalenii_PYR-1 IRTLLRGRGAPGGGSSRVVPMADVGTGLEQARVAAHSSVGEFTEYADLGP
MSMEG_3997|M.smegmatis_MC2_155 ADVHRAAATVRMLVDLGKSGATTLLRSWVHLSMAQLSEVIDDLRGYVLDP
Mflv_0801|M.gilvum_PYR-GCK SAIAQARIALTLAEHRGGRVGPDQLSTLESLLEQLPLAQLAPFRQLLIDP
:
MAB_0762|M.abscessus_ATCC_1997 LTEIG------------------VVDRQLLVDTFRQWVDCDGSIPATARV
TH_3478|M.thermoresistible__bu GAEI-------------------ASEHPHLSEAVVAFAHNGFSTAAAARV
MAV_4933|M.avium_104 LSVG--------------------GSSRELIATVRTYLACGMHVERTATR
Mvan_1854|M.vanbaalenii_PYR-1 LAAVLDGRTSRELRFLAAVLDPLAGNDEDLIATLAAFLRHNGQMEAAAAE
MSMEG_3997|M.smegmatis_MC2_155 LRKVH--------------------DRELIVETIQTFADN-GSVADTASV
Mflv_0801|M.gilvum_PYR-GCK LTELD------------------TSRGTQHVRTLRTFVACNGSLSETAKE
:. : :*
MAB_0762|M.abscessus_ATCC_1997 LFCHPNTVRYRLRRLKQLTGRDVARPRDIAELHLAVEADRRLSWA-----
TH_3478|M.thermoresistible__bu LHLHPNTVSYRLDRWTQLTGWELNDFEGLARSVVCIALSARRASGPSATA
MAV_4933|M.avium_104 LFVHQNTVRYRLARFEELTGASLRDTEVVTEVWWVLELAAMRL-------
Mvan_1854|M.vanbaalenii_PYR-1 LRVHRHTLRNRMRRIHQLLGDDLTSADSRAQLWLALRAFQLLENRRAPAG
MSMEG_3997|M.smegmatis_MC2_155 LYCHRNTVMNRIRRFEEATGISLRSPRSLAMVQLCLLPA-----------
Mflv_0801|M.gilvum_PYR-GCK LFLHTNTVRHRLGRIQEITGRDPLQHNDLTTFVIGMWAADRGE-------
* * :*: *: * : * . : :
MAB_0762|M.abscessus_ATCC_1997 ----
TH_3478|M.thermoresistible__bu SG--
MAV_4933|M.avium_104 ----
Mvan_1854|M.vanbaalenii_PYR-1 RCDS
MSMEG_3997|M.smegmatis_MC2_155 ----
Mflv_0801|M.gilvum_PYR-GCK ----