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M. thermoresistible (build 8) TH_3478 (-)

annotation: -
coordinates: 4567661 - 4568785
length: 375

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3478--100% (375)-
M. thermoresistible (build 8)TH_1338-9e-1027.97% (261) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_3143-7e-0725.75% (334) PUTATIVE putative conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1218c-1e-0525.94% (293) hypothetical protein Mb1218c
M. gilvum PYR-GCKMflv_2780-2e-0926.25% (259) hypothetical protein Mflv_2780
M. tuberculosis H37RvRv1186c-1e-0525.94% (293) hypothetical protein Rv1186c
M. leprae Br4923MLBr_01652-3e-0925.73% (307) hypothetical protein MLBr_01652
M. abscessus ATCC 19977MAB_0912-1e-3532.30% (356) hypothetical protein MAB_0912
M. marinum MMMAR_3335-3e-0825.99% (304) hypothetical protein MMAR_3335
M. avium 104MAV_4933-6e-1024.36% (390) hypothetical protein MAV_4933
M. smegmatis MC2 155MSMEG_4324-3e-0926.67% (255) hypothetical protein MSMEG_4324
M. ulcerans Agy99MUL_1307-2e-0825.99% (304) hypothetical protein MUL_1307
M. vanbaalenii PYR-1Mvan_1323-3e-0532.14% (112) transcriptional regulator, CdaR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2780|M.gilvum_PYR-GCK          --------------------------------------------MPDNNR
MSMEG_4324|M.smegmatis_MC2_155      --------------------------------------------MPDN-R
MMAR_3335|M.marinum_M               --------------------------------------------MNDN-Q
MUL_1307|M.ulcerans_Agy99           --------------------------------------------MNNN-Q
MLBr_01652|M.leprae_Br4923          --------------------------------------------MNHN-H
Mb1218c|M.bovis_AF2122/97           ------MRIAGVGLGQLLLALDATVVSLVDAPRGLDLPVASTALIDSDDV
Rv1186c|M.tuberculosis_H37Rv        ------MRIAGVGLGQLLLALDATVVSLVDAPRGLDLPVASTALIDSDDV
TH_3478|M.thermoresistible__bu      --------------------------------------------------
MAB_0912|M.abscessus_ATCC_1997      --------------------------------------------MSMDRP
MAV_4933|M.avium_104                --------------------MKDFRAPVNGVDGDSASALVAVPKSQGAQT
Mvan_1323|M.vanbaalenii_PYR-1       MRHDDDRMTVAGLLDESLMSGAHVLTGADRLDQQVHWVLPLSEVMSRHDA
                                                                                      

Mflv_2780|M.gilvum_PYR-GCK          FVPPN------STVEV---LGNVPDSTLRRLKQYSGRLATEAVHAMEERL
MSMEG_4324|M.smegmatis_MC2_155      FVPPK------STVEV---LEAVPDSLLRRLKQYSGRLATEAVHAMEQRL
MMAR_3335|M.marinum_M               FSAIARLGSARSPLEL---LETVPDSLLRRLKQYSGRLATEAVSAMQERL
MUL_1307|M.ulcerans_Agy99           FSAIARLGSARSPLEL---LETVPDSLLRRLKQYSGRLATEAVSAMQERL
MLBr_01652|M.leprae_Br4923          FVPAP---PRRLPLEL---LDTVPDSLLRRLKQYSGRLATEAVTAMQERL
Mb1218c|M.bovis_AF2122/97           RLGLAAAAGSADVFFL---IGVTDDEAVRWVDDQARQRAPVAIFVKHPSD
Rv1186c|M.tuberculosis_H37Rv        RLGLAAAAGSADVFFL---IGVTDDEAVRWVDDQARQRAPVAIFVKHPSD
TH_3478|M.thermoresistible__bu      --------MLDELEDI---AAQVTAIIRAELPAYAAIPLDDHRAAVQDQL
MAB_0912|M.abscessus_ATCC_1997      DAHELCAAVAQRIERN---EPDLTARIRAELPSYTRLSESEHRRTVHELA
MAV_4933|M.avium_104                IRPDSVSRLVGALLDD---HAAVVGRVRSVIRSRLPVYRSVADEALEAEL
Mvan_1323|M.vanbaalenii_PYR-1       LDGVAVYTRPEALLGNGGTLAPLAARGATALLVDGTVPADFPTAAVPADM
                                                                  :             .     

Mflv_2780|M.gilvum_PYR-GCK          PFFADMEASQRASVQLVVQT-------AVVNFVEWMRDPQSDVSYTAQAF
MSMEG_4324|M.smegmatis_MC2_155      PFFAELDASQRASVQLVVQT-------AVVNFVEWMRNPESNVGYTAQAF
MMAR_3335|M.marinum_M               PFFADLEASQRASVALVVQT-------AVVNFAEWMQNPRSDVSYTAQAF
MUL_1307|M.ulcerans_Agy99           PFFADLEASQRASVALVVQT-------AVVNFAEWMQNPRSDVSYTAQAF
MLBr_01652|M.leprae_Br4923          PFFADLEASQRASVTLVVQT-------AVVNFVQWMQNPHSDVSYTAQAF
Mb1218c|M.bovis_AF2122/97           SVVAGAVRAGSAVVAVEPRARWERLYHLVNHVLEHHGDRADPTDDSGTDL
Rv1186c|M.tuberculosis_H37Rv        SVVAGAVRAGSAVVAVEPRARWERLYHLVNHVLEHHGDRADPTDDSGTDL
TH_3478|M.thermoresistible__bu      SVILTGLREMRGPGPADLIT--------AERLGRRRAEQGIDISALMRAY
MAB_0912|M.abscessus_ATCC_1997      RRLLTGIADREGPVAEHLQY--------TRRAALRRMQLGVSAYDMMRSF
MAV_4933|M.avium_104                EWVLRSAVGGREALHEPQIAG-------LAAIGEARARDGVPVDDMLRAW
Mvan_1323|M.vanbaalenii_PYR-1       VVVEMAFPVGFAALNRLLAERALSQEVHAMRYATHVHASLAGLFHRGAGL
                                      .                                               

Mflv_2780|M.gilvum_PYR-GCK          EVVPQDLRRRIA--------------------------------------
MSMEG_4324|M.smegmatis_MC2_155      EVVPQDLRRRVA--------------------------------------
MMAR_3335|M.marinum_M               ELVPQDLTRRIA--------------------------------------
MUL_1307|M.ulcerans_Agy99           ELVPQDLTRRIA--------------------------------------
MLBr_01652|M.leprae_Br4923          ELVPQDLARRIA--------------------------------------
Mb1218c|M.bovis_AF2122/97           FGLAQSLADRIHGMISIEDAQSHVLAYSASNDEADELRRLSILGRAGPPE
Rv1186c|M.tuberculosis_H37Rv        FGLAQSLADRIHGMISIEDAQSHVLAYSASNDEADELRRLSILGRAGPPE
TH_3478|M.thermoresistible__bu      ELPLQELWQRYAG-------------------------------------
MAB_0912|M.abscessus_ATCC_1997      HIVSSGIWNALQ--------------------------------------
MAV_4933|M.avium_104                RIGVEVVVECAR--------------------------------------
Mvan_1323|M.vanbaalenii_PYR-1       QLLVREVSNLARNPAMALDARG----------------------------
                                          :                                           

Mflv_2780|M.gilvum_PYR-GCK          -------------LRQSVEMVRTTMEYFEEVVPLLAR-------------
MSMEG_4324|M.smegmatis_MC2_155      -------------LRQSVEMVRTSMEFFEEAVPLLAR-------------
MMAR_3335|M.marinum_M               -------------LRHTVDMVRVTMEFFEEVVPLLAR-------------
MUL_1307|M.ulcerans_Agy99           -------------LRHTVDMVRVTMEFFEEVVPLLAR-------------
MLBr_01652|M.leprae_Br4923          -------------LRHTVDMVRVTMEFFEEVVPLLAR-------------
Mb1218c|M.bovis_AF2122/97           HLQWIGQWGIFDALRAGREVVRVAERPELGLRPRLAIGIHQPGVGALRPP
Rv1186c|M.tuberculosis_H37Rv        HLQWIGQWGIFDALRPGREVVRVAERPELGLRPRLAIGIHQPGVGALRPP
TH_3478|M.thermoresistible__bu      -------------------LVCDGKQ------------------------
MAB_0912|M.abscessus_ATCC_1997      --------------------TAPEAN------------------------
MAV_4933|M.avium_104                -----------------EAARRLGVD------------------------
Mvan_1323|M.vanbaalenii_PYR-1       -----------NVVAHNGFTAETAAALTESILPLLTADLPAAARLSAHHD
                                                                                      

Mflv_2780|M.gilvum_PYR-GCK          ---------------SEDQLTALTAGILRYSRDLAFAAASAYADQA----
MSMEG_4324|M.smegmatis_MC2_155      ---------------SEEQLTALTAGILRYSRDLAFAAASAYADQA----
MMAR_3335|M.marinum_M               ---------------SEEQLTALTVGILKYSRDLAFTAASAYADAA----
MUL_1307|M.ulcerans_Agy99           ---------------SEEQLTALTVGILKYSRDLAFTAASAYADAA----
MLBr_01652|M.leprae_Br4923          ---------------SEEQLTALTVGILKYSRDLAFTAATAYADAA----
Mb1218c|M.bovis_AF2122/97           VFAGTI--------WVQQGSQPLADDAEEMLRGAAVLAARIMSRLA----
Rv1186c|M.tuberculosis_H37Rv        VFAGTI--------WVQQGSQPLADDAEEMLRGAAVLAARIMSRLA----
TH_3478|M.thermoresistible__bu      ----------------AQELIALAPSLLRWLHQLGGAAATGHQIVT----
MAB_0912|M.abscessus_ATCC_1997      ----------------DALLLDLVEPLATWTEALTAAVVDAFIEEQ----
MAV_4933|M.avium_104                ----------------DARVLELVQSALAWSDIAMATSAKAHRRTE----
Mvan_1323|M.vanbaalenii_PYR-1       TRVERFGAPGGGVWTVISTAIRLGKAFEGWVLVVVPSAEPGGHDLARHIV
                                                          *                           

Mflv_2780|M.gilvum_PYR-GCK          ----------------EARGAWDTRIESNLVDAVVRGDI-GPDLQSQAAA
MSMEG_4324|M.smegmatis_MC2_155      ----------------EARGAWDIRMEANIVDAVVRGDT-GPELQSQAAA
MMAR_3335|M.marinum_M               ----------------EARGTWDSRMEASVVDAVVRGDT-GPELLSRAAA
MUL_1307|M.ulcerans_Agy99           ----------------EARGTWDSRMEASVVDAVVRGDT-GPELLSRAAA
MLBr_01652|M.leprae_Br4923          ----------------EARGTWDSRMEASVVDAVVRGDT-GPELLSRAAA
Mb1218c|M.bovis_AF2122/97           ----------------TQPNTHALRVQQLLGLAELNATT-APVDVSTIAR
Rv1186c|M.tuberculosis_H37Rv        ----------------TQPNTHALRVQQLLGLAELNATT-APVDVSTIAR
TH_3478|M.thermoresistible__bu      ----------------TSQLANEVRLQAQLLDLITADPA-GAQTLVLAGR
MAB_0912|M.abscessus_ATCC_1997      ----------------PVRSVHEMKTRREFFAELGDRSR-AERTAETART
MAV_4933|M.avium_104                ----------------RALALEAEESDAEFVRGALMGSL-PAAELRMHAE
Mvan_1323|M.vanbaalenii_PYR-1       VTEQATAIIGSEMLRQHSVDEAEERARGDFVQALVHGHFSSEHDMRARAD
                                                            .    .                    

Mflv_2780|M.gilvum_PYR-GCK          LN-WDATAPATVIVGTPRPDR--------TEFVVDDVHDVVKRHGRAALS
MSMEG_4324|M.smegmatis_MC2_155      LN-WDATAPATVIVGLPRADR--------IEMARDDVHAVVRRNDRAALS
MMAR_3335|M.marinum_M               LN-WDTTAPATVVVGTPASARDGSDG---SERAIQDVRDAAAQHGRAALT
MUL_1307|M.ulcerans_Agy99           LN-WDTTAPATVVVGTPASARDGSDG---SERAIQDVRDAAAQHGRAALT
MLBr_01652|M.leprae_Br4923          LN-WDTTAPATVVVGTPTPNHDGPNGQVSSERASQEVREIAARHGRAALT
Mb1218c|M.bovis_AF2122/97           EL-GVAAEGNATLIGFDTAENRDTAVRHVRLVDVMALSASAFRHDAQVAA
Rv1186c|M.tuberculosis_H37Rv        EL-GVAAEGNATLIGFDTAENRDTAVRHVRLVDVMALSASAFRHDAQVAA
TH_3478|M.thermoresistible__bu      LG-LDTGGTFQAVGFTPSVDP----------HRLERVIVRLRIHAGPVVA
MAB_0912|M.abscessus_ATCC_1997      LA-FDVDGEFQALCSPRSVWP---------DTEVEMLQRTTRHLPGVVQC
MAV_4933|M.avium_104                LRGLDPGAEYVAVRARLGGDGP-------HLRLEQSLGFQDPAHSRRGLC
Mvan_1323|M.vanbaalenii_PYR-1       YHEIDIDSVFGVFVAPGAVPRGVDNPAASMVRLARYAANVAPDPAVRSYV
                                               ..                                     

Mflv_2780|M.gilvum_PYR-GCK          DVHGTWLVAIVSGNLSPTDRFLAELMSVFADGP----------VVIGPTA
MSMEG_4324|M.smegmatis_MC2_155      DVHGTWLVTIVSGPLSATDRFLADLMSVFADGP----------VVIGPTT
MMAR_3335|M.marinum_M               DVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGP----------VVIGPTA
MUL_1307|M.ulcerans_Agy99           DVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGP----------VVIGPTA
MLBr_01652|M.leprae_Br4923          DVHGTWLVAIISGQLAPTDKFFSDLLHAFSDGP----------VVIGPTA
Mb1218c|M.bovis_AF2122/97           NGSRIYVLLPQTTTGRAVTSWVRGTISALRAELGVALR----AAIAGPVA
Rv1186c|M.tuberculosis_H37Rv        NGSRIYVLLPQTTTGRAVTSWVRGTISALRAELGVALR----AAIAGPVA
TH_3478|M.thermoresistible__bu      GVHDGMFVVLQQHDR---TGVVTQLCRPHAAGG-----------VFGIGE
MAB_0912|M.abscessus_ATCC_1997      GVWGNVLVALVQDCDVENVLRSAQAISGASAEY-------------GVGL
MAV_4933|M.avium_104                ALLDGDLAGFLIEPPRDVEGVVG----------------------FGPPR
Mvan_1323|M.vanbaalenii_PYR-1       TVLGDVLVVVRSLRGADDTAMRKEMTRYAEAMADELQNRRGTPAAVAYSR
                                          .                                       .   

Mflv_2780|M.gilvum_PYR-GCK          --ATLGGAHRSATEAVAGMNSVAGWPGAPRPVAARELLPERALLGDVTAA
MSMEG_4324|M.smegmatis_MC2_155      --PTLTAAHRSATEAISGMNAVAGWPSAPRPVSARELLPERALLGDADAV
MMAR_3335|M.marinum_M               --PMLTAAYHSASEAISGMNAVAGWRGAPRPVLARELLPERALMGDASAI
MUL_1307|M.ulcerans_Agy99           --PMLTAAYHSASEAISGMNAVAGWRGASRPVLARELLPERALMGDASAI
MLBr_01652|M.leprae_Br4923          --PMLTAAYHSASEAVSGMNAVAGWSGAPRPVQARELLPERALMGDASAI
Mb1218c|M.bovis_AF2122/97           GLAEVNPARVEVDRVLESAERHPILGQVTSLAEARTTVLLDEIVTLVGTD
Rv1186c|M.tuberculosis_H37Rv        GLAEVNPARVEVDRVLESAERHPILGQVTSLAEARTTVLLDEIVTLVGTD
TH_3478|M.thermoresistible__bu      PRYGLQGAALSIGDARRAAGLAAVLG--HDVVFSRHWLLASVLA---SAD
MAB_0912|M.abscessus_ATCC_1997      ARRGLAGAHQSCIDAER-ALRMARVQKLPAARFVDWWLEASLLD--FQSQ
MAV_4933|M.avium_104                PLTRLSESYRMAARALVTAEACGLRGAYDIAALG--LRTAVAIDADVGEL
Mvan_1323|M.vanbaalenii_PYR-1       PARGAQEVAGSYREARIALGIARRLGHTGAVSYQDLRSFTVLADVADTDQ
                                                  .                                   

Mflv_2780|M.gilvum_PYR-GCK          TALEAEVMRPLADAGPALMDTLDAYLDSGGAIEACARKLFIHPNTVRYRL
MSMEG_4324|M.smegmatis_MC2_155      TALETEVMRPLADAGPALTETLDAFLDSGGAIEACARKLFVHPNTVRYRL
MMAR_3335|M.marinum_M               VALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRL
MUL_1307|M.ulcerans_Agy99           VALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRL
MLBr_01652|M.leprae_Br4923          VALHTDVMLPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRL
Mb1218c|M.bovis_AF2122/97           QRLVDPRIRDLGAQDPVLAQTLRAYLDAFGDIGAAARSLQVHPNTVRYRI
Rv1186c|M.tuberculosis_H37Rv        QRLVDPRIRDLGAQDPVLAQTLRAYLDAFGDIGAAARSLQVHPNTVRYRI
TH_3478|M.thermoresistible__bu      HLDHLGRGAEIASEHPHLSEAVVAFAHNGFSTAAAARVLHLHPNTVSYRL
MAB_0912|M.abscessus_ATCC_1997      LAVLFDAVHETATKYPDLAEAVLVFADCGFSLARAARRLQVHPNSVAYRL
MAV_4933|M.avium_104                LRKRYLEPLSVGGSSRELIATVRTYLACGMHVERTATRLFVHQNTVRYRL
Mvan_1323|M.vanbaalenii_PYR-1       SRALVADVLGPLRSAPDLLDFLIGYLAHGGNVNATARALNVHRNTMLTKL
                                                     *   :  :          *  * :* *::  ::

Mflv_2780|M.gilvum_PYR-GCK          KRITDFTGRDPTVPRDAYVLRVASSLGRLTRQASQSPPLSARSGPRGGVA
MSMEG_4324|M.smegmatis_MC2_155      RRIADFTGRDPAVPRDAYVLRVASTVGRLSKHAYRASTINSAVSVVPTIR
MMAR_3335|M.marinum_M               KRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPV
MUL_1307|M.ulcerans_Agy99           KRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPV
MLBr_01652|M.leprae_Br4923          KRITDFTGHDPTLPRDAYVLRVAATVGKLNYPTHH---------------
Mb1218c|M.bovis_AF2122/97           RRIEQLLSTSLGDPD----VRLLFSLGLRAMERTA---------------
Rv1186c|M.tuberculosis_H37Rv        RRIEQLLSTSLGDPD----VRLLFSLGLRAMERTA---------------
TH_3478|M.thermoresistible__bu      DRWTQLTGWELNDFEGLARSVVCIALSARRASGPSATASG----------
MAB_0912|M.abscessus_ATCC_1997      TRWQQLSGADPRTFDGLARSVIACRLTCPV--------------------
MAV_4933|M.avium_104                ARFEELTGASLRDTEVVTEVWWVLELAAMRL-------------------
Mvan_1323|M.vanbaalenii_PYR-1       DRVSRATGLDIRLPDNQFTVWLAIRLDMLTEVHAAVDREAKFR-------
                                     *     . .               :                        

Mflv_2780|M.gilvum_PYR-GCK          SVTNPGTSP-
MSMEG_4324|M.smegmatis_MC2_155      PATSAGSRGT
MMAR_3335|M.marinum_M               RRGTEGP---
MUL_1307|M.ulcerans_Agy99           RRGTEGP---
MLBr_01652|M.leprae_Br4923          ----------
Mb1218c|M.bovis_AF2122/97           ----------
Rv1186c|M.tuberculosis_H37Rv        ----------
TH_3478|M.thermoresistible__bu      ----------
MAB_0912|M.abscessus_ATCC_1997      ----------
MAV_4933|M.avium_104                ----------
Mvan_1323|M.vanbaalenii_PYR-1       ----------