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VGEQLLARVDELCAEQCRIIRERVAAYRDPVLVTDEDLFAAGRDQMVYVLAAMGSGAPDTSAAARVGRLR AEQGVPLADVMSAYRAGGQFLWDALSQAIDAAGLSRQELRAAASQAWQNHDRYTDAMAEGYRDVVVEQLI QRDQERAALVSGLIDGRFPAGITAWNAAHQLGLPESGAFVVVAIESGPLDYRTLRSAEKALRDQGFASAW RVDPDMQVGIVALPTPSRLEELGETLRNLGVRRIGVSPVYDGYPPPGPPLNYAKAALLAATEDDPVVAFD ANPYAVAAITDPQTMARYRDLVLGSLTEIGVVDRQLLVDTFRQWVDCDGSIPATARVLFCHPNTVRYRLR RLKQLTGRDVARPRDIAELHLAVEADRRLSWA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0762 | - | - | 100% (382) | hypothetical protein MAB_0762 |
| M. abscessus ATCC 19977 | MAB_2653c | - | 1e-31 | 29.19% (322) | hypothetical protein MAB_2653c |
| M. abscessus ATCC 19977 | MAB_1880c | - | 3e-11 | 39.56% (91) | hypothetical protein MAB_1880c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2266 | - | 3e-12 | 39.80% (98) | hypothetical protein Mb2266 |
| M. gilvum PYR-GCK | Mflv_0936 | - | 7e-13 | 24.69% (324) | hypothetical protein Mflv_0936 |
| M. tuberculosis H37Rv | Rv2242 | - | 3e-12 | 39.80% (98) | hypothetical protein Rv2242 |
| M. leprae Br4923 | MLBr_01652 | - | 2e-11 | 51.79% (56) | hypothetical protein MLBr_01652 |
| M. marinum M | MMAR_3335 | - | 7e-12 | 38.78% (98) | hypothetical protein MMAR_3335 |
| M. avium 104 | MAV_4933 | - | 1e-13 | 25.20% (381) | hypothetical protein MAV_4933 |
| M. smegmatis MC2 155 | MSMEG_3552 | - | 8e-15 | 26.14% (329) | hypothetical protein MSMEG_3552 |
| M. thermoresistible (build 8) | TH_1338 | - | 7e-15 | 27.68% (289) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1307 | - | 4e-12 | 38.78% (98) | hypothetical protein MUL_1307 |
| M. vanbaalenii PYR-1 | Mvan_3753 | - | 4e-12 | 27.30% (282) | hypothetical protein Mvan_3753 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3335|M.marinum_M ----------MNDNQFSAIARLGSARSPLELLETVPDSLLRRLKQYSGRL
MUL_1307|M.ulcerans_Agy99 ----------MNNNQFSAIARLGSARSPLELLETVPDSLLRRLKQYSGRL
MLBr_01652|M.leprae_Br4923 ----------MNHNHFVPAP---PRRLPLELLDTVPDSLLRRLKQYSGRL
Mb2266|M.bovis_AF2122/97 ----------MNDNQLAPVAR---PRSPLELLDTVPDSLLRRLKQYSGRL
Rv2242|M.tuberculosis_H37Rv ----------MNDNQLAPVAR---PRSPLELLDTVPDSLLRRLKQYSGRL
TH_1338|M.thermoresistible__bu ----------VPDNRFVPPQ------STLEVLESVPESVLRRLKQYSGRL
Mvan_3753|M.vanbaalenii_PYR-1 ----------MTDNRFIPPR------STVEVLENVPESTLRRLKQYSGRL
MAB_0762|M.abscessus_ATCC_1997 --------------------------------------MGEQLLARVDEL
Mflv_0936|M.gilvum_PYR-GCK ----------MPEPATGAPR-----------IVDLPRETLEAMRAGLPAL
MAV_4933|M.avium_104 MKDFRAPVNGVDGDSASALVAVPKSQGAQTIRPDSVSRLVGALLDDHAAV
MSMEG_3552|M.smegmatis_MC2_155 ----------MTFMRKSSDAG--------QWSRSRWMELINSVTDHRDQL
: :
MMAR_3335|M.marinum_M ATEAVSAMQERLPFFADLEASQRASVALVVQTAVVN-FAEWMQNPRSD--
MUL_1307|M.ulcerans_Agy99 ATEAVSAMQERLPFFADLEASQRASVALVVQTAVVN-FAEWMQNPRSD--
MLBr_01652|M.leprae_Br4923 ATEAVTAMQERLPFFADLEASQRASVTLVVQTAVVN-FVQWMQNPHSD--
Mb2266|M.bovis_AF2122/97 ATEAVSAMQERLPFFADLEASQRASVALVVQTAVVN-FVEWMHDPHSD--
Rv2242|M.tuberculosis_H37Rv ATEAVSAMQERLPFFADLEASQRASVALVVQTAVVN-FVEWMHDPHSD--
TH_1338|M.thermoresistible__bu ATEAVHTMEERLPFFADLEASQRASVHLVVQTAVVN-FVEWMRDPRSN--
Mvan_3753|M.vanbaalenii_PYR-1 ATQAVHAMEERLPFFAELDASQRASVQLVVQTAVVN-FAEWMRDPRSN--
MAB_0762|M.abscessus_ATCC_1997 CAEQCRIIRERVAAYRDPVLVTDEDLFAAGRDQMVY-VLAAMGSGAPD--
Mflv_0936|M.gilvum_PYR-GCK VDRMVEAVIAEVPLLAQAAQESWRPVIDTSAQLLLGSLIDELGTSTGPPT
MAV_4933|M.avium_104 VGRVRSVIRSRLPVYRSVADEALEAELEWVLRSAVG-GREALHEPQIAG-
MSMEG_3552|M.smegmatis_MC2_155 VDAFMAQVDDGRRFYDSKVETADLRESSRAAFTMLLRQLRGTPTSEED--
: . :
MMAR_3335|M.marinum_M -------VSYTAQAFELVPQD-LTRRIALRHTVDMVRVTMEFFEEVVPLL
MUL_1307|M.ulcerans_Agy99 -------VSYTAQAFELVPQD-LTRRIALRHTVDMVRVTMEFFEEVVPLL
MLBr_01652|M.leprae_Br4923 -------VSYTAQAFELVPQD-LARRIALRHTVDMVRVTMEFFEEVVPLL
Mb2266|M.bovis_AF2122/97 -------VGYTAQAFELVPQD-LTRRIALRQTVDMVRVTMEFFEEVVPLL
Rv2242|M.tuberculosis_H37Rv -------VGYTAQAFELVPQD-LTRRIALRQTVDMVRVTMEFFEEVVPLL
TH_1338|M.thermoresistible__bu -------VTYTMQAFEVVPQD-LTRRIALRQTVEMVRTTMEFFEQVVPLL
Mvan_3753|M.vanbaalenii_PYR-1 -------VSYTAQAFEVVPQD-LRRRIALRQSVEMVRVTMEFFEEVVPLL
MAB_0762|M.abscessus_ATCC_1997 -------TSAAARVGRLRAEQGVPLADVMSAYRAGGQFLWDALSQAIDAA
Mflv_0936|M.gilvum_PYR-GCK AVPMQEVLDIAHRFGRREARNGRPAEVQLAAYRVGARELWRDWSALAAQG
MAV_4933|M.avium_104 ----------LAAIGEARARDGVPVDDMLRAWRIGVEVVVECAREAARRL
MSMEG_3552|M.smegmatis_MC2_155 -------LRITRELGVRRASQGVESEKLTAAIHRDFSVLWAAFRELAEDD
. :
MMAR_3335|M.marinum_M ARSEEQLTALTVGILKYSRDLAFTAASAYADAAEARGTWDSRMEASVVDA
MUL_1307|M.ulcerans_Agy99 ARSEEQLTALTVGILKYSRDLAFTAASAYADAAEARGTWDSRMEASVVDA
MLBr_01652|M.leprae_Br4923 ARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDA
Mb2266|M.bovis_AF2122/97 ARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDA
Rv2242|M.tuberculosis_H37Rv ARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDA
TH_1338|M.thermoresistible__bu ARSEEQVTALTAGILRYSRDLAFAAATAYADAAEARGAWDTRMEANVVDA
Mvan_3753|M.vanbaalenii_PYR-1 ARSEDQLAAMTAGILRYSRDLAFAAATAYADQAEARGAWDTRMEANLVDA
MAB_0762|M.abscessus_ATCC_1997 GLSRQELRAAASQAWQNHDRYTDAMAEGYRDVVVEQLIQRDQERAALVSG
Mflv_0936|M.gilvum_PYR-GCK GVDRDQVSAFAEMFFAYLDLISAAGVAGHAQEQSRSGLDRERRRERLVRM
MAV_4933|M.avium_104 GVDDARVLELVQSALAWSDIAMATSAKAHRRTERALALEAEESDAEFVRG
MSMEG_3552|M.smegmatis_MC2_155 D--AAVLAEHAEDVWRVVDGFAGRIHAAYFDEVIAIAQERSLSVQSLLAK
: . .: .:
MMAR_3335|M.marinum_M VVRGDTGPELLSRAAALNWDTTAPATVVVGTPASARDGSDG---SERAIQ
MUL_1307|M.ulcerans_Agy99 VVRGDTGPELLSRAAALNWDTTAPATVVVGTPASARDGSDG---SERAIQ
MLBr_01652|M.leprae_Br4923 VVRGDTGPELLSRAAALNWDTTAPATVVVGTPTPNHDGPNGQVSSERASQ
Mb2266|M.bovis_AF2122/97 VVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQ
Rv2242|M.tuberculosis_H37Rv VVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQ
TH_1338|M.thermoresistible__bu VVRGAVGPELQSQAAALNWDATAPATVVVGLPRPDR--------LEVVSQ
Mvan_3753|M.vanbaalenii_PYR-1 VVRGGTRPELQSQAAALNWDATAPATVIVGMPRPDR--------AEFAGD
MAB_0762|M.abscessus_ATCC_1997 LIDGRFPAGITAWNAAHQLGLPESGAFVVVAIESGP-------LDYRTLR
Mflv_0936|M.gilvum_PYR-GCK LLSDTASDELDLAAEYATWATPRTLTAVAMPTRQER--------GATAIT
MAV_4933|M.avium_104 ALMGSLPAAELRMHAELRGLDPGAEYVAVRARLGGD----------GPHL
MSMEG_3552|M.smegmatis_MC2_155 LVTDEYPSLTFIARAGQALSIRETDGIWVAAALASEG---------TPLQ
: . . .
MMAR_3335|M.marinum_M DVRDAAAQHG-----RAALTDVHGTWLVAIVSGHLSPTDKVFKDLLEAFS
MUL_1307|M.ulcerans_Agy99 DVRDAAAQHG-----RAALTDVHGTWLVAIVSGHLSPTDKVFKDLLEAFS
MLBr_01652|M.leprae_Br4923 EVREIAARHG-----RAALTDVHGTWLVAIISGQLAPTDKFFSDLLHAFS
Mb2266|M.bovis_AF2122/97 DVRDTAARHG-----RAALTDVHGTWLVAIVSGQLSPTEKFLKDLLAAFA
Rv2242|M.tuberculosis_H37Rv DVRDTAARHG-----RAALTDVHGTWLVAIVSGQLSPTEKFLKDLLAAFA
TH_1338|M.thermoresistible__bu DVHHVANRHG-----RTALSDVHGTWLVTIVSGALSPTDRFLTDLLDVFA
Mvan_3753|M.vanbaalenii_PYR-1 DVHEVADRNG-----RTALSDVHGTWLVAIISGGLSPTDRFLSELMTVFA
MAB_0762|M.abscessus_ATCC_1997 SAEKALRDQG-----FASAWRVDPDMQVGIVALPTPSRLEELGETLRNLG
Mflv_0936|M.gilvum_PYR-GCK SDPRTLRVPD-----DAVDSRIG--MHVVLVCDVGGSARASFVASLAGTG
MAV_4933|M.avium_104 RLEQSLGFQD-----PAHSRRGLCALLDGDLAGFLIEPPRDVEG------
MSMEG_3552|M.smegmatis_MC2_155 QFAERLRRRGRLAYTYAMGQCIVAVWVADVVGSELDGVPDGCTSDPEYAD
. : :
MMAR_3335|M.marinum_M DGPVVIGPTAPMLTAAYHSASEAISGMNAVAGWRGAPRPVLARELLP-ER
MUL_1307|M.ulcerans_Agy99 DGPVVIGPTAPMLTAAYHSASEAISGMNAVAGWRGASRPVLARELLP-ER
MLBr_01652|M.leprae_Br4923 DGPVVIGPTAPMLTAAYHSASEAVSGMNAVAGWSGAPRPVQARELLP-ER
Mb2266|M.bovis_AF2122/97 DAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLP-ER
Rv2242|M.tuberculosis_H37Rv DAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLP-ER
TH_1338|M.thermoresistible__bu DGPVVLGPTAPTLSAAYRSATEAIAGMNAVAGWSGAPRPVPARELLP-ER
Mvan_3753|M.vanbaalenii_PYR-1 DGPVVIGPTAPTLGAAHRSATEAIAGMNAVAGWAGAPRPVSARELLP-ER
MAB_0762|M.abscessus_ATCC_1997 VRRIGVSPVYDGYPPPGPPLNYAKAALLAAT----EDDPVVAFDANPYAV
Mflv_0936|M.gilvum_PYR-GCK ---AVVGPAR-SWTDAQSSVRRVLRAMRLRR--PDGGDVLDTEEILP-EL
MAV_4933|M.avium_104 --VVGFGPPRPLTRLSESYRMAARALVTAEACGLRGAYDIAALGLRT---
MSMEG_3552|M.smegmatis_MC2_155 LKPVRCGVSPLHRGVSQLRSAAQIACEIALSMHPDHIGPATAADVWP-LV
. . : .
MMAR_3335|M.marinum_M ALMGDASAIVALHTDVMRPLADAG----PTLIETLDAYLDCGGAIEACAR
MUL_1307|M.ulcerans_Agy99 ALMGDASAIVALHTDVMRPLADAG----PTLIETLDAYLDCGGAIEACAR
MLBr_01652|M.leprae_Br4923 ALMGDASAIVALHTDVMLPLADAG----PTLIETLDAYLDCGGAIEACAR
Mb2266|M.bovis_AF2122/97 ALMGDASAIVALHTDVMRPLADAG----PTLIETLDAYLDCGGAIEACAR
Rv2242|M.tuberculosis_H37Rv ALMGDASAIVALHTDVMRPLADAG----PTLIETLDAYLDCGGAIEACAR
TH_1338|M.thermoresistible__bu ALLGDQTAIAALESEVMRPLADAG----PTLTETLDAFLESGGAIEACAR
Mvan_3753|M.vanbaalenii_PYR-1 ALLGDATAGAALEAEVMRPLSDAG----PALMETLDAYLDSGGAIEACAR
MAB_0762|M.abscessus_ATCC_1997 AAITDPQTMARYRDLVLGSLTEIGVVDRQLLVDTFRQWVDCDGSIPATAR
Mflv_0936|M.gilvum_PYR-GCK VVGADADALADLRARALAPLADFPEASRDRLTETLRSWLLHQGRRDDIAA
MAV_4933|M.avium_104 AVAIDADVGELLRKRYLEPLSVGG--SSRELIATVRTYLACGMHVERTAT
MSMEG_3552|M.smegmatis_MC2_155 AGAALHSRLPVLEESIRGPLRDCRPAELKVLMETISVFSG-NGDVSATAA
. . .* * *. : *
MMAR_3335|M.marinum_M KLFVHPNTIRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSG
MUL_1307|M.ulcerans_Agy99 KLFVHPNTIRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSG
MLBr_01652|M.leprae_Br4923 KLFVHPNTVRYRLKRITDFTGHDPTLPRDAYVLRVAATVGKLNYPTHH--
Mb2266|M.bovis_AF2122/97 KLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPH--
Rv2242|M.tuberculosis_H37Rv KLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPH--
TH_1338|M.thermoresistible__bu RLFVHPNTVRYRLRRIAEITGRDPAVPRDAYVLRVAVSVSRLTRQSYQSS
Mvan_3753|M.vanbaalenii_PYR-1 KLFVHPNTVRYRLKRIADFTGRDPTVPRDAYVLRVASSVGRLARQAHLSA
MAB_0762|M.abscessus_ATCC_1997 VLFCHPNTVRYRLRRLKQLTGRDVARPRDIAELHLAVEADRRLSWA----
Mflv_0936|M.gilvum_PYR-GCK DLFVSPSTIRYRLRQLRDAYGDRLRDPRTIAELTVALAMDVATLGGQTRP
MAV_4933|M.avium_104 RLFVHQNTVRYRLARFEELTGASLRDTEVVTEVWWVLELAAMRL------
MSMEG_3552|M.smegmatis_MC2_155 ELFCHRNTVMKRIRRLKELTGLDMTVPKDSARVLVALAPELAAVSD----
** .*: *: :: : * .. : .
MMAR_3335|M.marinum_M AANNTITPVPLPVRRGTEGP---
MUL_1307|M.ulcerans_Agy99 AANNTITPVPLPVRRGTEGP---
MLBr_01652|M.leprae_Br4923 -----------------------
Mb2266|M.bovis_AF2122/97 -----------------------
Rv2242|M.tuberculosis_H37Rv -----------------------
TH_1338|M.thermoresistible__bu TVNPDLGSTAGWRGQAAGGHRAM
Mvan_3753|M.vanbaalenii_PYR-1 APAAASAQAIGVASVTSPENLGT
MAB_0762|M.abscessus_ATCC_1997 -----------------------
Mflv_0936|M.gilvum_PYR-GCK AIVGG------------------
MAV_4933|M.avium_104 -----------------------
MSMEG_3552|M.smegmatis_MC2_155 -----------------------