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M. smegmatis MC2 155 MSMEG_3578 (-)

annotation: putative cyclase
coordinates: 3638039 - 3640156
length: 705

VLSRISIQSKLLAMLLVTSVLSAAVVGFIGYQSGRSSLRDSVFDRLTEIRTAQARQLETQFRSFRNSLVI
YTRGTTAIEAARAFTAGFDQLGDATISPAQQKAITDWYENQFSATTEHSDAADNLDGNEVDVEALLPSSN
PQKYLQALYTAPFTDWDKAIENDDAGDGSGWSAANALFNGFFREIVTRSGFDDALLLDTRGNVVYTAYKG
SDLGTNIYTGPYKGGELSEAYREALNSNTVDYVAVTDFGIYQPSGTPTAWMVSPIGGGGRIEGVLALQFP
ISVVNQLMTMDGKWEESGLGETGETYLVGPDGLMRSDSRLFLENPEQFKADVIEAGTPPGVAEQSILHGG
TTLVQPVSDEASKLAGQGQSGSIIERDYLGQETLQAYAPLDLTGLDWSVVAKIDTAEAFAPVTKFTRTLV
LSTVAMIFAVCIAAILLARVFVRPIRRLEAGAQQISAGDYGVALPVVSRDEFGDLTVAFNEMSRNLRIKE
DLLDEQRKENDRLLLSLMPEPVVQRYREGEETIAQDHQNVTVLFADLMGLDRLSASMSSDEHLSIVNKLV
RQFDAAAESLGVERVRTLHNGYLASCGLTVPRLDNVRRTVDFAFEMQRIVDRFRGETGYDLRLRAGIDTG
TVSSGLVGRSSLAYDMWGAAVDLAYQVQRGMPQPGVYVTDQVHDAVRDIRQFTAVGSVTVDGTERPIWRL
SERQS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3578--100% (705)putative cyclase
M. smegmatis MC2 155MSMEG_0228-2e-1125.00% (176) adenylate and guanylate cyclase catalytic domain-containing
M. smegmatis MC2 155MSMEG_6154-1e-0824.66% (146) adenylate cyclase, family protein 3

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2461c-0.059.89% (703) putative cyclase (adenylyl-or guanylyl-)(adenylate-or
M. gilvum PYR-GCKMflv_3576-1e-2226.19% (210) putative adenylate/guanylate cyclase
M. tuberculosis H37RvRv2435c-0.059.89% (703) cyclase
M. leprae Br4923MLBr_02341-1e-1026.59% (173) putative regulatory protein
M. abscessus ATCC 19977MAB_0490c-3e-0921.94% (237) putative adenylate cyclase
M. marinum MMMAR_3757-0.058.46% (703) adenylate or guanylate cyclase
M. avium 104MAV_1745-0.054.05% (703) adenylate and guanylate cyclase catalytic domain-containing
M. thermoresistible (build 8)TH_2298-0.067.38% (702) PROBABLE CYCLASE (ADENYLYL-OR GUANYLYL-)(ADENYLATE-OR
M. ulcerans Agy99MUL_3698-0.051.14% (704) adenylate or guanylate cyclase
M. vanbaalenii PYR-1Mvan_2839-8e-2226.67% (210) putative adenylate/guanylate cyclase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      -------------------------MLS------RISIQSKLLAMLLVTS
TH_2298|M.thermoresistible__bu      ---------------MAIRRKPRRHWTP------RFSIQSKLLMMLLTTS
Mb2461c|M.bovis_AF2122/97           MTSGEALDSVAESESTPAKKRHKNVLRR--RPRFRASIQSKLMVLLLLTS
Rv2435c|M.tuberculosis_H37Rv        MTSGEALDSVAESESTPAKKRHKNVLRR--RPRFRASIQSKLMVLLLLTS
MMAR_3757|M.marinum_M               -----------MVEGAPAHDGAKGTRRR--RPRFRVSIQSKLMVLLLLSS
MAV_1745|M.avium_104                MTTSELTDAESDIAPAPAPQPAKRTRRTPLRSRFRFGIQSKILITMLLSS
MUL_3698|M.ulcerans_Agy99           ------------------------MLRF-----LRVGIPAKLLVTLLVCS
MAB_0490c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02341|M.leprae_Br4923          ---------------------------------MTTALVCVACGAELRSI
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      VLSAAVVGFIGYQSGRSSLRDSVFDRLTEIRTAQARQLETQFRSFRNSLV
TH_2298|M.thermoresistible__bu      VLAVAVVGFIGYQSGRSSLRASAFDGLIEIRTSQARELETLFSDLTNSLV
Mb2461c|M.bovis_AF2122/97           IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLV
Rv2435c|M.tuberculosis_H37Rv        IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLV
MMAR_3757|M.marinum_M               IVSVAAIVAVGFHTGRSSLSAAAYGRLTQLRESQLRAVETLFSDLTNSLV
MAV_1745|M.avium_104                ILGVAVIGLIGAVSGRNALRQVESERLIELREGQKRAVQALFREVTNSLI
MUL_3698|M.ulcerans_Agy99           ILSVAVVGVIGYVSGRNALQRVAVERLHQLREAQKRQVEALFSELTKSVM
MAB_0490c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02341|M.leprae_Br4923          AKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMT
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      IYTRGTTAIEAARAFTAGFDQLGDATISPAQQKAITDWYENQFSATTEHS
TH_2298|M.thermoresistible__bu      IYSRGDTAAAAVTAFTDAFDELHDATVTPAQHRAIVDYYERHFGGDTTAT
Mb2461c|M.bovis_AF2122/97           IYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT
Rv2435c|M.tuberculosis_H37Rv        IYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT
MMAR_3757|M.marinum_M               IYARGLTVIDAVAQFTAGFDQLADATISPAQQESLVNYYNDQLIKPVEHL
MAV_1745|M.avium_104                VWSGGFTINEATAALTTGFAQLANATITPAQQQQLVNYYDNQMLKPIKHA
MUL_3698|M.ulcerans_Agy99           VYSNGMSANEATAALTDGFAQLANATVDPVQQQAIVDYYVNELIKPIDQA
MAB_0490c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02341|M.leprae_Br4923          ELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQ
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      DAADNLDGNEVDVEALLPSSNPQKYLQALYTAPFTDWDKAIENDDAGDGS
TH_2298|M.thermoresistible__bu      -------GSRLRVEALLPSGSAQRYLQAHYTAPFSDWDAAIDNDDAGDGS
Mb2461c|M.bovis_AF2122/97           T------GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGS
Rv2435c|M.tuberculosis_H37Rv        T------GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGS
MMAR_3757|M.marinum_M               T------GTKLDLEALLPTSPAQKYLQAYYTAPFTSDQDSMRLDDAGDGS
MAV_1745|M.avium_104                T------GDSIDINAVLPNSNAQKYVQAYYTAAPRPTPDSLPVQDAGDGS
MUL_3698|M.ulcerans_Agy99           T------GHELDLEAVLSASPAQTYLQAYYTAPFSSSSESMRFNNAGDGS
MAB_0490c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02341|M.leprae_Br4923          EKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGM
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      GWSAANALFNGFFREIVTRSGFDDALLLDTRGNVVYTAYKGSDLGTNIYT
TH_2298|M.thermoresistible__bu      AWSAANARFHDFFREIVERFEFEDALLIDTRGNVVYSAYKGVDLGTNLHT
Mb2461c|M.bovis_AF2122/97           AWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILT
Rv2435c|M.tuberculosis_H37Rv        AWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILT
MMAR_3757|M.marinum_M               AWSAANAEFNGYFREIVTRFDYDDAVLLDTRGNIVYSLSKDPDLGTNILT
MAV_1745|M.avium_104                AWSAANARFDFYVRDIATRFDYRDALLLDTQGNVVYSVMKGPDLGTNILT
MUL_3698|M.ulcerans_Agy99           AWSAANARFNDFFRGIVTRFQYRDALLLDLQGNVVYSVNEGPDLGTNLFT
MAB_0490c|M.abscessus_ATCC_199      ---MTGAEGRPDRRPLARAARYSRWVMRTPWPLFIMGIAQSNLVGALFVL
MLBr_02341|M.leprae_Br4923          AQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLL
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       -------------------------------------------MRPVCVP
MSMEG_3578|M.smegmatis_MC2_155      GPYKGGELSEAYREALNSNTVDYVAVTDFGIYQPSG-TPTAWMVSPIGGG
TH_2298|M.thermoresistible__bu      GPYRETALSEAYRKALGSNMVDHVGLTDFSTYQPTS-EPTAWMVSPVGTG
Mb2461c|M.bovis_AF2122/97           GPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAG
Rv2435c|M.tuberculosis_H37Rv        GPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAG
MMAR_3757|M.marinum_M               GPYRESNLRDAYLRALGANAVDFTWITDFEPYQPQLDAATAWLVSPVLQG
MAV_1745|M.avium_104                GPYRESKLREAYQKALASNDVDFVWITDFQPYQPQLDAPTAWVVSPVGMN
MUL_3698|M.ulcerans_Agy99           GPYRETNLRTAYQKALASNEIDFVWITDFQRYQPEVDAPTAWLVSPVGVD
MAB_0490c|M.abscessus_ATCC_199      GFLRFG--------LPPSDRVELTELGPTRLIILGFSLFILFVVGAIVST
MLBr_02341|M.leprae_Br4923          RVAEPRQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIG
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          ------------------MGRRQSVLMIAGWIAAAVSAAFGAFQLTLGGS
Mvan_2839|M.vanbaalenii_PYR-1       EVTLGRRAWSPSRHRHERVARRQRVLMIASWIAAAASVGFGVFQLTFGGP
MSMEG_3578|M.smegmatis_MC2_155      GRIEGVLALQFPISVVNQLMTMDGKWEESGLGETGETYLVGPDGLMRSDS
TH_2298|M.thermoresistible__bu      GRILGALALQFPIDKINRVMTADRQWESVGLGRTGETYLVGTDDLMRSDS
Mb2461c|M.bovis_AF2122/97           GKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDS
Rv2435c|M.tuberculosis_H37Rv        GKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDS
MMAR_3757|M.marinum_M               GRTEGVLALPLPIAKINKMMTADKNWQAAGMGTGTETYLAGPDNLMRSDS
MAV_1745|M.avium_104                GRIEGVMALPVPAAKINKIMTAGGHWEAAGMGPATETYLAGPDDLMRSDS
MUL_3698|M.ulcerans_Agy99           GKLQGVMALALPPTNLNQIMNANEKWEAVGMGRSTETYLAGSDNLMRSDS
MAB_0490c|M.abscessus_ATCC_199      YLLLPVLRWQYRSPDFESEGSEAVRVRALQMPFYRTVISVAT-WLVGGAI
MLBr_02341|M.leprae_Br4923          KTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLD
                                                                                   .  

Mflv_3576|M.gilvum_PYR-GCK          LWWLGAVN------VLCALVFLWIPRLCPLG--ELLAPLTFVTFAYMSVT
Mvan_2839|M.vanbaalenii_PYR-1       LWWLGAVN------IGCGVVFLAIPRLCPLG--ELIAPLTFVVFAYTSVG
MSMEG_3578|M.smegmatis_MC2_155      RLFLENPEQFKADVIEAGTPPGVAEQSILHGGTTLVQPVSDEASKLAGQG
TH_2298|M.thermoresistible__bu      RLFLEDPEQFKRAVVEAGTPPTVAEESLRSGGTTLVQPIRNEAVDRAQRG
Mb2461c|M.bovis_AF2122/97           RLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRG
Rv2435c|M.tuberculosis_H37Rv        RLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRG
MMAR_3757|M.marinum_M               RLFLQDPEEYRRQAVAAGTSPEVVNRAIQLGSTVLLQPVATAGLREAQRG
MAV_1745|M.avium_104                RVFVEDPQQYRRDAIDAGTPPDVVDRAIHLGGTTLVQPVATAGLRAAQRG
MUL_3698|M.ulcerans_Agy99           RLFLESPDEYRREALAGGTREDVVNKAMWLGTTVLVQPVPSAGLRAALRG
MAB_0490c|M.abscessus_ATCC_199      FVAVTWSSTHSSVLVAAFATVLGATTTSIIGYLQSERVLRPVAIQALRRG
MLBr_02341|M.leprae_Br4923          DRSARARVREQIPDADTQDLLLLDDLLGIADPAVELPRLDPDARRRRLTA
                                                                  .       :           

Mflv_3576|M.gilvum_PYR-GCK          FF----CYTIGTGSG-----------------MQFYFLVAASLVLLVLGI
Mvan_2839|M.vanbaalenii_PYR-1       FI----CYTIGTGSG-----------------LQFYFLVAASLVVLVLGI
MSMEG_3578|M.smegmatis_MC2_155      QS----GSIIERDYLGQETLQAYAPLDLTG--LDWSVVAKIDTAEAFAPV
TH_2298|M.thermoresistible__bu      QT----GTLIGTDYLGREALQSYAPVDLPG--LNWSIVAEKDTAEAFGPV
Mb2461c|M.bovis_AF2122/97           QT----GTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAV
Rv2435c|M.tuberculosis_H37Rv        QT----GTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAV
MMAR_3757|M.marinum_M               QT----GTVSAVDYTGNRELEAFAPLNIPNSDLHWSILATNDDSAAFAAA
MAV_1745|M.avium_104                ET----GVVTATDYMGNRELEAYAPLNIPNSDLHWSILATRDNSDAFARL
MUL_3698|M.ulcerans_Agy99           QS----GITKDTDYLGNRELEAYAPLDVPNSDLRWAILATRDDWDAYERL
MAB_0490c|M.abscessus_ATCC_199      VP----ENVTAPGVIVRQILTWALSTGVPILAIVLTVVGQRAG-YLKSNA
MLBr_02341|M.leprae_Br4923          LINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYR
                                                                        .:            

Mflv_3576|M.gilvum_PYR-GCK          ERVALAAVIAGVGVVITVVLELTVPEDRGLGPSWTLTAG-----------
Mvan_2839|M.vanbaalenii_PYR-1       ERIALAAAIAAAGVIITIVLELTVPDDRGLGPSWTLTAG-----------
MSMEG_3578|M.smegmatis_MC2_155      TKFTRTLVLSTVAMIFAVCIAAILLARVFVRPIRRLEAGAQQI-------
TH_2298|M.thermoresistible__bu      VEFTRTLVLSTVSIVFAVCLAAMLLARIFVRPVRRLEAGVRRV-------
Mb2461c|M.bovis_AF2122/97           ASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKI-------
Rv2435c|M.tuberculosis_H37Rv        ASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKI-------
MMAR_3757|M.marinum_M               AAFSKALVLVTVAMIVIICVFSMLIAQLMVRPIRRLEAGTEKI-------
MAV_1745|M.avium_104                GRFSKNLVIAVTAMIFVICVASMFVAQAAVRPVRRLEEGTRKI-------
MUL_3698|M.ulcerans_Agy99           SSFGRTVVLAVAGITLFICVVSMVLAKLLVRPIRRLEAGTEKI-------
MAB_0490c|M.abscessus_ATCC_199      DNLTGSILILAIIALAIGLMGTLLVATSIADPLRQLRWALSEV-------
MLBr_02341|M.leprae_Br4923          PEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITER
                                                           .           *  .           

Mflv_3576|M.gilvum_PYR-GCK          -----FISAVTSSAVMIVATIWYTLREIER----AESAMENEYERSERLL
Mvan_2839|M.vanbaalenii_PYR-1       -----FISAVVSSVVIIVATIWYTLREIDR----AEAAMAAEYERSEELL
MSMEG_3578|M.smegmatis_MC2_155      -SAGDYGVALPVVSRDEFGDLTVAFNEMSRNLRIKEDLLDEQRKENDRLL
TH_2298|M.thermoresistible__bu      -ATGDYHVRLPVTSHDEFGDLTAAFNDMSRNLATKEELLAEQRRENDRLL
Mb2461c|M.bovis_AF2122/97           -SAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLL
Rv2435c|M.tuberculosis_H37Rv        -SAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLL
MMAR_3757|M.marinum_M               -SGGDYDVAIPVKSRDEIGDLTAAFNEMSRSLNIKEDLLNEQRRENDRLL
MAV_1745|M.avium_104                -SSGDYDINIPVRARDEIGDLTAAFNEMSRNLAIKEELLNEQRRENDRLL
MUL_3698|M.ulcerans_Agy99           -RSGDYEVTVPVKSRDELGDLTAAFNEMSSNLKVKDQLLTEQRSQNEQLL
MAB_0490c|M.abscessus_ATCC_199      -QRGNYNAHVPIYDASELGLLQAGFNDMVRDLG--------ERQRLRDLF
MLBr_02341|M.leprae_Br4923          AAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAAR
                                         :            . :                             

Mflv_3576|M.gilvum_PYR-GCK          ANILPATIAERLKEPTRTVIADKYDDASILFADIAGYTKRASDTAPAE--
Mvan_2839|M.vanbaalenii_PYR-1       ANILPATIADRLKEPTRTVIADKYDDASILFADIAGYTKRASETPPSE--
MSMEG_3578|M.smegmatis_MC2_155      LSLMPEPVVQRYRE-GEETIAQDHQNVTVLFADLMGLDRLSASMSSDE--
TH_2298|M.thermoresistible__bu      LSLMPEPVVQRYRD-GEQTIAQDHQDVTVIFADIVGLDEVSFNLPSAE--
Mb2461c|M.bovis_AF2122/97           LSMMPEPVVERYRL-GEQTIAQEHQDVTVLFADILGVDEISSGLSGNE--
Rv2435c|M.tuberculosis_H37Rv        LSMMPEPVVERYRL-GEQTIAQEHQDVTVLFADILGVDEISSGLSGNE--
MMAR_3757|M.marinum_M               LSMMPEPVVQRYRE-GEQTIAQEHQDVTVIFADILGLDEVSRSLSGNE--
MAV_1745|M.avium_104                LALMPESVLQRYRE-GEETIAQKHQDVAIIYADIVGLDELFTEMPEAQ--
MUL_3698|M.ulcerans_Agy99           LALMPEPVVQRYRA-DGEVIAEEHQDVTVIFAELIGLEEISDGLSGDE--
MAB_0490c|M.abscessus_ATCC_199      GRYVGEDVARRALEYGTELGGQE-RSVAVLFVDLVGSTQLASTRGPAV--
MLBr_02341|M.leprae_Br4923          IDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSVDELIDANLVDQVRF
                                       :                       : :  ::                

Mflv_3576|M.gilvum_PYR-GCK          LVRFLDLLYTDLDALVDRHGLEKVKTSGDSYMVVSGVPTPRPDHLEALAT
Mvan_2839|M.vanbaalenii_PYR-1       LVRFLDRLYTDLDALVDRHGLEKVKTSGDSYMVVSGVPNPRADHLEALAL
MSMEG_3578|M.smegmatis_MC2_155      HLSIVNKLVRQFDAAAESLGVERVRTLHNGYLASCGLTVPRLDNVRRTVD
TH_2298|M.thermoresistible__bu      AVPIVNELIRQFDAAADHHGVERVRTMHNGYIASCGLSVPRLDNVRRTVD
Mb2461c|M.bovis_AF2122/97           LVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVD
Rv2435c|M.tuberculosis_H37Rv        LVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVD
MMAR_3757|M.marinum_M               LIAIVDDLFRQFDSAAESLGVERIRTLHNGYLASCGVTTPRLDNVARTVA
MAV_1745|M.avium_104                LVGTVDELFRQFDSAAETLGVERIRTFHNGYLASCGVVTPRLDSIHRAVD
MUL_3698|M.ulcerans_Agy99           LVGIVDELFRQFDSAAQSLGVEPIRTFHNGYLAACGATTPRLDNVHRGIE
MAB_0490c|M.abscessus_ATCC_199      VVRVLNEFFRVIVDTVNKHGGFVNKFQGDAALAIFGAPIDHPDGAAAALA
MLBr_02341|M.leprae_Br4923          TAPVEYAFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVDQHAV
                                           :   :   .   .               .      .       

Mflv_3576|M.gilvum_PYR-GCK          LALDMSEAVADLKDPRGRDVPLRIGMAMGPVVAGVVGAKK--------FF
Mvan_2839|M.vanbaalenii_PYR-1       LALDMADAVADLKDPQGHDVPLRIGMASGPVVAGVVGAKK--------FF
MSMEG_3578|M.smegmatis_MC2_155      FAFEMQRIVDRFRGETGYDLRLRAGIDTGTVSSGLVGRSS--------LA
TH_2298|M.thermoresistible__bu      FALDLQRIIDRFTRETGHRLELRAGIDTGTVKSGLVDRSR--------LA
Mb2461c|M.bovis_AF2122/97           FALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSS--------VV
Rv2435c|M.tuberculosis_H37Rv        FALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSS--------VV
MMAR_3757|M.marinum_M               FALEMQRIIERFNHQSGHQLRLRAGINTGNVISGLVGRTS--------VV
MAV_1745|M.avium_104                FALEIGRIIDRFNSQTGHQLGLRIGVNTGNVVSGLVGRSG--------LV
MUL_3698|M.ulcerans_Agy99           FALEIELIVNRFANQSQHPLRVRVGVTTGRVVSGRVGRSN--------LA
MAB_0490c|M.abscessus_ATCC_199      AARELSGELTNVLGSND----FGIGVSAGRAIAGHIGAQAR-------FE
MLBr_02341|M.leprae_Br4923          LIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTA
                                       :       .                  . :. :.             

Mflv_3576|M.gilvum_PYR-GCK          YDVWGDAVNVASRMETTDEE--GRIQVPDNVYQRLRH--AFVLEERGLID
Mvan_2839|M.vanbaalenii_PYR-1       YDVWGDAVNVASRMETTDVE--GRIQVPDNVYERLRD--RFVLEERGVVD
MSMEG_3578|M.smegmatis_MC2_155      YDMWGAAVDLAYQVQRGMPQ--PGVYVTDQVHDAVRD--IRQFTAVGSVT
TH_2298|M.thermoresistible__bu      YDMWGSAVNIAYQVQTGTAK--PGIFVTTRVRDVLRD--TYRFEQAGQID
Mb2461c|M.bovis_AF2122/97           YDMWGAAVSLAYQMHSGSPQ--PGIYVTSQVYEAMRD--VWQFTAAGTIS
Rv2435c|M.tuberculosis_H37Rv        YDMWGAAVSLAYQMHSGSPQ--PGIYVTSQVYEAMRD--VWQFTAAGTIS
MMAR_3757|M.marinum_M               YDMWGAAVSTAYQMHSGSPQ--PGIYVTSQVYEAMRD--ERQFAPAGTIA
MAV_1745|M.avium_104                YDMWGGAVSLAYQMHSGSPQ--PGIYVSSQVYEAMRD--VRQFAPAGTIS
MUL_3698|M.ulcerans_Agy99           YDMWGGAVQMAYRMLGHLSD--PGIYVSARVHDAMRE--IWTFTPAGAIS
MAB_0490c|M.abscessus_ATCC_199      YTVIGDPVNEAARLTELAKNEPGNVLASASAVMEARDEEALRWDVGETVE
MLBr_02341|M.leprae_Br4923          EDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVA
                                          .:  * :           .  .       :            : 

Mflv_3576|M.gilvum_PYR-GCK          VKGKGPMHTWYLVGHRARAVTPSSSPP
Mvan_2839|M.vanbaalenii_PYR-1       VKGKGPMHTWYLVAHRAEAVTPSGSPT
MSMEG_3578|M.smegmatis_MC2_155      VDGT-ERPIWRLSERQS----------
TH_2298|M.thermoresistible__bu      IDGA-AEPVWRLTEQRS----------
Mb2461c|M.bovis_AF2122/97           VGGL-EEPIYRLSERS-----------
Rv2435c|M.tuberculosis_H37Rv        VGGL-EEPIYRLSERS-----------
MMAR_3757|M.marinum_M               VGGA-EQQIYRMSEQS-----------
MAV_1745|M.avium_104                VGGT-DQAIYRLLER------------
MUL_3698|M.ulcerans_Agy99           VRGS-QQQIWQVSERR-----------
MAB_0490c|M.abscessus_ATCC_199      LRGRTVSTQVARPRHG-----------
MLBr_02341|M.leprae_Br4923          TVGPAIDHVYQDRLH------------
                                      *           :