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VEGAPAHDGAKGTRRRRPRFRVSIQSKLMVLLLLSSIVSVAAIVAVGFHTGRSSLSAAAYGRLTQLRESQ LRAVETLFSDLTNSLVIYARGLTVIDAVAQFTAGFDQLADATISPAQQESLVNYYNDQLIKPVEHLTGTK LDLEALLPTSPAQKYLQAYYTAPFTSDQDSMRLDDAGDGSAWSAANAEFNGYFREIVTRFDYDDAVLLDT RGNIVYSLSKDPDLGTNILTGPYRESNLRDAYLRALGANAVDFTWITDFEPYQPQLDAATAWLVSPVLQG GRTEGVLALPLPIAKINKMMTADKNWQAAGMGTGTETYLAGPDNLMRSDSRLFLQDPEEYRRQAVAAGTS PEVVNRAIQLGSTVLLQPVATAGLREAQRGQTGTVSAVDYTGNRELEAFAPLNIPNSDLHWSILATNDDS AAFAAAAAFSKALVLVTVAMIVIICVFSMLIAQLMVRPIRRLEAGTEKISGGDYDVAIPVKSRDEIGDLT AAFNEMSRSLNIKEDLLNEQRRENDRLLLSMMPEPVVQRYREGEQTIAQEHQDVTVIFADILGLDEVSRS LSGNELIAIVDDLFRQFDSAAESLGVERIRTLHNGYLASCGVTTPRLDNVARTVAFALEMQRIIERFNHQ SGHQLRLRAGINTGNVISGLVGRTSVVYDMWGAAVSTAYQMHSGSPQPGIYVTSQVYEAMRDERQFAPAG TIAVGGAEQQIYRMSEQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3757 | - | - | 100% (719) | adenylate or guanylate cyclase |
| M. marinum M | MMAR_3755 | - | 0.0 | 60.56% (720) | adenylate or guanylate cyclase |
| M. marinum M | MMAR_2428 | cya | 9e-27 | 32.35% (204) | membrane-anchored adenylyl cyclase Cya |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2461c | - | 0.0 | 81.31% (717) | putative cyclase (adenylyl-or guanylyl-)(adenylate-or |
| M. gilvum PYR-GCK | Mflv_3576 | - | 4e-26 | 29.05% (210) | putative adenylate/guanylate cyclase |
| M. tuberculosis H37Rv | Rv2435c | - | 0.0 | 81.31% (717) | cyclase |
| M. leprae Br4923 | MLBr_02341 | - | 8e-13 | 27.68% (177) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_4523 | - | 6e-13 | 22.85% (267) | putative adenylate cyclase |
| M. avium 104 | MAV_1745 | - | 0.0 | 67.88% (716) | adenylate and guanylate cyclase catalytic domain-containing |
| M. smegmatis MC2 155 | MSMEG_3578 | - | 0.0 | 58.46% (703) | putative cyclase |
| M. thermoresistible (build 8) | TH_2298 | - | 0.0 | 56.29% (707) | PROBABLE CYCLASE (ADENYLYL-OR GUANYLYL-)(ADENYLATE-OR |
| M. ulcerans Agy99 | MUL_3698 | - | 0.0 | 60.40% (697) | adenylate or guanylate cyclase |
| M. vanbaalenii PYR-1 | Mvan_2839 | - | 9e-27 | 29.05% (210) | putative adenylate/guanylate cyclase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3576|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2461c|M.bovis_AF2122/97 MTSGEALDSVAESESTPAKKRHKNVLRR--RPRFRASIQSKLMVLLLLTS
Rv2435c|M.tuberculosis_H37Rv MTSGEALDSVAESESTPAKKRHKNVLRR--RPRFRASIQSKLMVLLLLTS
MMAR_3757|M.marinum_M -----------MVEGAPAHDGAKGTRRR--RPRFRVSIQSKLMVLLLLSS
MAV_1745|M.avium_104 MTTSELTDAESDIAPAPAPQPAKRTRRTPLRSRFRFGIQSKILITMLLSS
MUL_3698|M.ulcerans_Agy99 ------------------------MLRF-----LRVGIPAKLLVTLLVCS
MSMEG_3578|M.smegmatis_MC2_155 -------------------------MLS------RISIQSKLLAMLLVTS
TH_2298|M.thermoresistible__bu ---------------MAIRRKPRRHWTP------RFSIQSKLLMMLLTTS
MAB_4523|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 ------------MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYK
Mflv_3576|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2461c|M.bovis_AF2122/97 IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLV
Rv2435c|M.tuberculosis_H37Rv IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLV
MMAR_3757|M.marinum_M IVSVAAIVAVGFHTGRSSLSAAAYGRLTQLRESQLRAVETLFSDLTNSLV
MAV_1745|M.avium_104 ILGVAVIGLIGAVSGRNALRQVESERLIELREGQKRAVQALFREVTNSLI
MUL_3698|M.ulcerans_Agy99 ILSVAVVGVIGYVSGRNALQRVAVERLHQLREAQKRQVEALFSELTKSVM
MSMEG_3578|M.smegmatis_MC2_155 VLSAAVVGFIGYQSGRSSLRDSVFDRLTEIRTAQARQLETQFRSFRNSLV
TH_2298|M.thermoresistible__bu VLAVAVVGFIGYQSGRSSLRASAFDGLIEIRTSQARELETLFSDLTNSLV
MAB_4523|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 QVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFT
Mflv_3576|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2461c|M.bovis_AF2122/97 IYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT
Rv2435c|M.tuberculosis_H37Rv IYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT
MMAR_3757|M.marinum_M IYARGLTVIDAVAQFTAGFDQLADATISPAQQESLVNYYNDQLIKPVEHL
MAV_1745|M.avium_104 VWSGGFTINEATAALTTGFAQLANATITPAQQQQLVNYYDNQMLKPIKHA
MUL_3698|M.ulcerans_Agy99 VYSNGMSANEATAALTDGFAQLANATVDPVQQQAIVDYYVNELIKPIDQA
MSMEG_3578|M.smegmatis_MC2_155 IYTRGTTAIEAARAFTAGFDQLGDATISPAQQKAITDWYENQFSATTEHS
TH_2298|M.thermoresistible__bu IYSRGDTAAAAVTAFTDAFDELHDATVTPAQHRAIVDYYERHFGGDTTAT
MAB_4523|M.abscessus_ATCC_1997 MMERLREWFRAMHVLGPRWSVFVASMVGINAATLLLLFYFLRHWMPFKRP
MLBr_02341|M.leprae_Br4923 GDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLR
Mflv_3576|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2461c|M.bovis_AF2122/97 T------GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGS
Rv2435c|M.tuberculosis_H37Rv T------GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGS
MMAR_3757|M.marinum_M T------GTKLDLEALLPTSPAQKYLQAYYTAPFTSDQDSMRLDDAGDGS
MAV_1745|M.avium_104 T------GDSIDINAVLPNSNAQKYVQAYYTAAPRPTPDSLPVQDAGDGS
MUL_3698|M.ulcerans_Agy99 T------GHELDLEAVLSASPAQTYLQAYYTAPFSSSSESMRFNNAGDGS
MSMEG_3578|M.smegmatis_MC2_155 DAADNLDGNEVDVEALLPSSNPQKYLQALYTAPFTDWDKAIENDDAGDGS
TH_2298|M.thermoresistible__bu -------GSRLRVEALLPSGSAQRYLQAHYTAPFSDWDAAIDNDDAGDGS
MAB_4523|M.abscessus_ATCC_1997 AG------------DWVFENGPPLFWLLFGIMIVTSVGWALHMEHR----
MLBr_02341|M.leprae_Br4923 VG--------LNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV
Mflv_3576|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1 -----------------------------MRPVCVPEVTLG---RRAWSP
Mb2461c|M.bovis_AF2122/97 AWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILT
Rv2435c|M.tuberculosis_H37Rv AWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILT
MMAR_3757|M.marinum_M AWSAANAEFNGYFREIVTRFDYDDAVLLDTRGNIVYSLSKDPDLGTNILT
MAV_1745|M.avium_104 AWSAANARFDFYVRDIATRFDYRDALLLDTQGNVVYSVMKGPDLGTNILT
MUL_3698|M.ulcerans_Agy99 AWSAANARFNDFFRGIVTRFQYRDALLLDLQGNVVYSVNEGPDLGTNLFT
MSMEG_3578|M.smegmatis_MC2_155 GWSAANALFNGFFREIVTRSGFDDALLLDTRGNVVYTAYKGSDLGTNIYT
TH_2298|M.thermoresistible__bu AWSAANARFHDFFREIVERFEFEDALLIDTRGNVVYSAYKGVDLGTNLHT
MAB_4523|M.abscessus_ATCC_1997 ------------------------LARWYCRGGPPTALELRTALTAPLQQ
MLBr_02341|M.leprae_Br4923 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSE
Mflv_3576|M.gilvum_PYR-GCK -------MGRRQSVLMIAGWIAAAVSAAFGAFQLTLGGSLWWLGAVNVLC
Mvan_2839|M.vanbaalenii_PYR-1 SRHRHERVARRQRVLMIASWIAAAASVGFGVFQLTFGGPLWWLGAVNIGC
Mb2461c|M.bovis_AF2122/97 GPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAG
Rv2435c|M.tuberculosis_H37Rv GPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAG
MMAR_3757|M.marinum_M GPYRESNLRDAYLRALGANAVDFTWITDFEPYQPQLDAATAWLVSPVLQG
MAV_1745|M.avium_104 GPYRESKLREAYQKALASNDVDFVWITDFQPYQPQLDAPTAWVVSPVGMN
MUL_3698|M.ulcerans_Agy99 GPYRETNLRTAYQKALASNEIDFVWITDFQRYQPEVDAPTAWLVSPVGVD
MSMEG_3578|M.smegmatis_MC2_155 GPYKGGELSEAYREALNSNTVDYVAVTDFGIYQPS-GTPTAWMVSPIGGG
TH_2298|M.thermoresistible__bu GPYRETALSEAYRKALGSNMVDHVGLTDFSTYQPT-SEPTAWMVSPVGTG
MAB_4523|M.abscessus_ATCC_1997 SLLHLGGWAIGATVFIAAGAMHDSKWTLATIIGCVQSATASFGITYLLGE
MLBr_02341|M.leprae_Br4923 STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAK
: : . . . :
Mflv_3576|M.gilvum_PYR-GCK ALVFLWIPRLCPLGEL----------------------------LAPLTF
Mvan_2839|M.vanbaalenii_PYR-1 GVVFLAIPRLCPLGEL----------------------------IAPLTF
Mb2461c|M.bovis_AF2122/97 GKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDS
Rv2435c|M.tuberculosis_H37Rv GKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDS
MMAR_3757|M.marinum_M GRTEGVLALPLPIAKINKMMTADKNWQAAGMGTGTETYLAGPDNLMRSDS
MAV_1745|M.avium_104 GRIEGVMALPVPAAKINKIMTAGGHWEAAGMGPATETYLAGPDDLMRSDS
MUL_3698|M.ulcerans_Agy99 GKLQGVMALALPPTNLNQIMNANEKWEAVGMGRSTETYLAGSDNLMRSDS
MSMEG_3578|M.smegmatis_MC2_155 GRIEGVLALQFPISVVNQLMTMDGKWEESGLGETGETYLVGPDGLMRSDS
TH_2298|M.thermoresistible__bu GRILGALALQFPIDKINRVMTADRQWESVGLGRTGETYLVGTDDLMRSDS
MAB_4523|M.abscessus_ATCC_1997 RILRPIAAKALSASEFHG----------------------------RFAP
MLBr_02341|M.leprae_Br4923 GLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISG---LDDRSARARVRE
.
Mflv_3576|M.gilvum_PYR-GCK VTFAYMSVTFFCYTIGTGSG------------------------------
Mvan_2839|M.vanbaalenii_PYR-1 VVFAYTSVGFICYTIGTGSG------------------------------
Mb2461c|M.bovis_AF2122/97 RLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRG
Rv2435c|M.tuberculosis_H37Rv RLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRG
MMAR_3757|M.marinum_M RLFLQDPEEYRRQAVAAGTSPEVVNRAIQLGSTVLLQPVATAGLREAQRG
MAV_1745|M.avium_104 RVFVEDPQQYRRDAIDAGTPPDVVDRAIHLGGTTLVQPVATAGLRAAQRG
MUL_3698|M.ulcerans_Agy99 RLFLESPDEYRREALAGGTREDVVNKAMWLGTTVLVQPVPSAGLRAALRG
MSMEG_3578|M.smegmatis_MC2_155 RLFLENPEQFKADVIEAGTPPGVAEQSILHGGTTLVQPVSDEASKLAGQG
TH_2298|M.thermoresistible__bu RLFLEDPEQFKRAVVEAGTPPTVAEESLRSGGTTLVQPIRNEAVDRAQRG
MAB_4523|M.abscessus_ATCC_1997 SVFVRVRLSWWIGTLAPAIG------------------------------
MLBr_02341|M.leprae_Br4923 QIPDADTQDLLLLDDLLGIADPAVELPRLDPDARRRRLTALINVAQLALS
.
Mflv_3576|M.gilvum_PYR-GCK ----------------------------MQFYFLVAASLVLLVLGIERVA
Mvan_2839|M.vanbaalenii_PYR-1 ----------------------------LQFYFLVAASLVVLVLGIERIA
Mb2461c|M.bovis_AF2122/97 QTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFS
Rv2435c|M.tuberculosis_H37Rv QTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFS
MMAR_3757|M.marinum_M QTGTVSAVDYTGNRELEAFAPLNIPNSDLHWSILATNDDSAAFAAAAAFS
MAV_1745|M.avium_104 ETGVVTATDYMGNRELEAYAPLNIPNSDLHWSILATRDNSDAFARLGRFS
MUL_3698|M.ulcerans_Agy99 QSGITKDTDYLGNRELEAYAPLDVPNSDLRWAILATRDDWDAYERLSSFG
MSMEG_3578|M.smegmatis_MC2_155 QSGSIIERDYLGQETLQAYAPLDLTG--LDWSVVAKIDTAEAFAPVTKFT
TH_2298|M.thermoresistible__bu QTGTLIGTDYLGREALQSYAPVDLPG--LNWSIVAEKDTAEAFGPVVEFT
MAB_4523|M.abscessus_ATCC_1997 ----------------------------IIALCGMALWKPEDLTSTRDLA
MLBr_02341|M.leprae_Br4923 RPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHV
Mflv_3576|M.gilvum_PYR-GCK LAAVIAGVGVVITVVLELTVPEDRGLGP--SWTLTAG--------FISAV
Mvan_2839|M.vanbaalenii_PYR-1 LAAAIAAAGVIITIVLELTVPDDRGLGP--SWTLTAG--------FISAV
Mb2461c|M.bovis_AF2122/97 RALVLVTVGIIVVICVASMLIAHAMVRP--IRRLEVGTQKISAGDYEVNI
Rv2435c|M.tuberculosis_H37Rv RALVLVTVGIIVVICVASMLIAHAMVRP--IRRLEVGTQKISAGDYEVNI
MMAR_3757|M.marinum_M KALVLVTVAMIVIICVFSMLIAQLMVRP--IRRLEAGTEKISGGDYDVAI
MAV_1745|M.avium_104 KNLVIAVTAMIFVICVASMFVAQAAVRP--VRRLEEGTRKISSGDYDINI
MUL_3698|M.ulcerans_Agy99 RTVVLAVAGITLFICVVSMVLAKLLVRP--IRRLEAGTEKIRSGDYEVTV
MSMEG_3578|M.smegmatis_MC2_155 RTLVLSTVAMIFAVCIAAILLARVFVRP--IRRLEAGAQQISAGDYGVAL
TH_2298|M.thermoresistible__bu RTLVLSTVSIVFAVCLAAMLLARIFVRP--VRRLEAGVRRVATGDYHVRL
MAB_4523|M.abscessus_ATCC_1997 LTVLLIVSTTLVGSYGLALLTAGQLADP--VRQLRTAISDVAQGDFNARV
MLBr_02341|M.leprae_Br4923 VGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQE
: . :
Mflv_3576|M.gilvum_PYR-GCK TSSAVMIVATIWYTLREIER----AESAMENEYERSERLLANILPATIAE
Mvan_2839|M.vanbaalenii_PYR-1 VSSVVIIVATIWYTLREIDR----AEAAMAAEYERSEELLANILPATIAD
Mb2461c|M.bovis_AF2122/97 PVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE
Rv2435c|M.tuberculosis_H37Rv PVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE
MMAR_3757|M.marinum_M PVKSRDEIGDLTAAFNEMSRSLNIKEDLLNEQRRENDRLLLSMMPEPVVQ
MAV_1745|M.avium_104 PVRARDEIGDLTAAFNEMSRNLAIKEELLNEQRRENDRLLLALMPESVLQ
MUL_3698|M.ulcerans_Agy99 PVKSRDELGDLTAAFNEMSSNLKVKDQLLTEQRSQNEQLLLALMPEPVVQ
MSMEG_3578|M.smegmatis_MC2_155 PVVSRDEFGDLTVAFNEMSRNLRIKEDLLDEQRKENDRLLLSLMPEPVVQ
TH_2298|M.thermoresistible__bu PVTSHDEFGDLTAAFNDMSRNLATKEELLAEQRRENDRLLLSLMPEPVVQ
MAB_4523|M.abscessus_ATCC_1997 EVYDGSELGVLQAGFNRMMQ--------VGEERRQLRELFGKHVGADVAS
MLBr_02341|M.leprae_Br4923 ITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQ
. : : : .
Mflv_3576|M.gilvum_PYR-GCK RLKEPTRTVIADKYDDASILFADIAGYTKRASDTAPAE--LVRFLDLLYT
Mvan_2839|M.vanbaalenii_PYR-1 RLKEPTRTVIADKYDDASILFADIAGYTKRASETPPSE--LVRFLDRLYT
Mb2461c|M.bovis_AF2122/97 RYRL-GEQTIAQEHQDVTVLFADILGVDEISSGLSGNE--LVKIVDELVR
Rv2435c|M.tuberculosis_H37Rv RYRL-GEQTIAQEHQDVTVLFADILGVDEISSGLSGNE--LVKIVDELVR
MMAR_3757|M.marinum_M RYRE-GEQTIAQEHQDVTVIFADILGLDEVSRSLSGNE--LIAIVDDLFR
MAV_1745|M.avium_104 RYRE-GEETIAQKHQDVAIIYADIVGLDELFTEMPEAQ--LVGTVDELFR
MUL_3698|M.ulcerans_Agy99 RYRA-DGEVIAEEHQDVTVIFAELIGLEEISDGLSGDE--LVGIVDELFR
MSMEG_3578|M.smegmatis_MC2_155 RYRE-GEETIAQDHQNVTVLFADLMGLDRLSASMSSDE--HLSIVNKLVR
TH_2298|M.thermoresistible__bu RYRD-GEQTIAQDHQDVTVIFADIVGLDEVSFNLPSAE--AVPIVNELIR
MAB_4523|M.abscessus_ATCC_1997 QALQ-LGTNLGGENRYVAVFFVDMIGSTSMAADRDPEE--VLTILNDFFR
MLBr_02341|M.leprae_Br4923 LLVAAAVIGFRFGSDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRH
: : : :: :
Mflv_3576|M.gilvum_PYR-GCK DLDALVDRHGLEKVKTSGDSYMVVSGVPTPRPDHLEALATLALDMSEAVA
Mvan_2839|M.vanbaalenii_PYR-1 DLDALVDRHGLEKVKTSGDSYMVVSGVPNPRADHLEALALLALDMADAVA
Mb2461c|M.bovis_AF2122/97 QFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVD
Rv2435c|M.tuberculosis_H37Rv QFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVD
MMAR_3757|M.marinum_M QFDSAAESLGVERIRTLHNGYLASCGVTTPRLDNVARTVAFALEMQRIIE
MAV_1745|M.avium_104 QFDSAAETLGVERIRTFHNGYLASCGVVTPRLDSIHRAVDFALEIGRIID
MUL_3698|M.ulcerans_Agy99 QFDSAAQSLGVEPIRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVN
MSMEG_3578|M.smegmatis_MC2_155 QFDAAAESLGVERVRTLHNGYLASCGLTVPRLDNVRRTVDFAFEMQRIVD
TH_2298|M.thermoresistible__bu QFDAAADHHGVERVRTMHNGYIASCGLSVPRLDNVRRTVDFALDLQRIID
MAB_4523|M.abscessus_ATCC_1997 IVVEVVDSRGGFVNKFVGDEALSVFGAPLHRPDATTACLAAARELR---D
MLBr_02341|M.leprae_Br4923 PLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVDQHAVLIAEHLEAAG
. . . . . :
Mflv_3576|M.gilvum_PYR-GCK DLKDPRGRDVPLRIGMAMGPVVAGVVGAKK--------FFYDVWGDAVNV
Mvan_2839|M.vanbaalenii_PYR-1 DLKDPQGHDVPLRIGMASGPVVAGVVGAKK--------FFYDVWGDAVNV
Mb2461c|M.bovis_AF2122/97 RFNCQTGNDLHLRVGINTGDVISGLVGRSS--------VVYDMWGAAVSL
Rv2435c|M.tuberculosis_H37Rv RFNCQTGNDLHLRVGINTGDVISGLVGRSS--------VVYDMWGAAVSL
MMAR_3757|M.marinum_M RFNHQSGHQLRLRAGINTGNVISGLVGRTS--------VVYDMWGAAVST
MAV_1745|M.avium_104 RFNSQTGHQLGLRIGVNTGNVVSGLVGRSG--------LVYDMWGGAVSL
MUL_3698|M.ulcerans_Agy99 RFANQSQHPLRVRVGVTTGRVVSGRVGRSN--------LAYDMWGGAVQM
MSMEG_3578|M.smegmatis_MC2_155 RFRGETGYDLRLRAGIDTGTVSSGLVGRSS--------LAYDMWGAAVDL
TH_2298|M.thermoresistible__bu RFTRETGHRLELRAGIDTGTVKSGLVDRSR--------LAYDMWGSAVNI
MAB_4523|M.abscessus_ATCC_1997 RLNEDFPHPFEFAIGVSAGLAVAGNVGATAR-------YEYSVIGDPVNE
MLBr_02341|M.leprae_Br4923 DLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCI
: . . :. *. . .:
Mflv_3576|M.gilvum_PYR-GCK ASRMETTDEEGR----IQVPDNVYQRLRHAFVLEERGLIDVKGKGPMHTW
Mvan_2839|M.vanbaalenii_PYR-1 ASRMETTDVEGR----IQVPDNVYERLRDRFVLEERGVVDVKGKGPMHTW
Mb2461c|M.bovis_AF2122/97 AYQMHSGSPQPG----IYVTSQVYEAMRDVWQFTAAGTISVGGL-EEPIY
Rv2435c|M.tuberculosis_H37Rv AYQMHSGSPQPG----IYVTSQVYEAMRDVWQFTAAGTISVGGL-EEPIY
MMAR_3757|M.marinum_M AYQMHSGSPQPG----IYVTSQVYEAMRDERQFAPAGTIAVGGA-EQQIY
MAV_1745|M.avium_104 AYQMHSGSPQPG----IYVSSQVYEAMRDVRQFAPAGTISVGGT-DQAIY
MUL_3698|M.ulcerans_Agy99 AYRMLGHLSDPG----IYVSARVHDAMREIWTFTPAGAISVRGS-QQQIW
MSMEG_3578|M.smegmatis_MC2_155 AYQVQRGMPQPG----VYVTDQVHDAVRDIRQFTAVGSVTVDGT-ERPIW
TH_2298|M.thermoresistible__bu AYQVQTGTAKPG----IFVTTRVRDVLRDTYRFEQAGQIDIDGA-AEPVW
MAB_4523|M.abscessus_ATCC_1997 ASRLTELAKHRPSRLLASTNALYFADPDEQKHWEHGDSVLLRGRTRATHL
MLBr_02341|M.leprae_Br4923 APRTRLCGIAWRG---RFNSSSGFDEVRQLCNATGDKAPLAVATVGPAID
* : . .
Mflv_3576|M.gilvum_PYR-GCK YLVGHRARAVTPSSSPP
Mvan_2839|M.vanbaalenii_PYR-1 YLVAHRAEAVTPSGSPT
Mb2461c|M.bovis_AF2122/97 RLSERS-----------
Rv2435c|M.tuberculosis_H37Rv RLSERS-----------
MMAR_3757|M.marinum_M RMSEQS-----------
MAV_1745|M.avium_104 RLLER------------
MUL_3698|M.ulcerans_Agy99 QVSERR-----------
MSMEG_3578|M.smegmatis_MC2_155 RLSERQS----------
TH_2298|M.thermoresistible__bu RLTEQRS----------
MAB_4523|M.abscessus_ATCC_1997 AWPAGT-----------
MLBr_02341|M.leprae_Br4923 HVYQDRLH---------