For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_3698 (-)

annotation: adenylate or guanylate cyclase
coordinates: 4116246 - 4118357
length: 703

LRFLRVGIPAKLLVTLLVCSILSVAVVGVIGYVSGRNALQRVAVERLHQLREAQKRQVEALFSELTKSVM
VYSNGMSANEATAALTDGFAQLANATVDPVQQQAIVDYYVNELIKPIDQATGHELDLEAVLSASPAQTYL
QAYYTAPFSSSSESMRFNNAGDGSAWSAANARFNDFFRGIVTRFQYRDALLLDLQGNVVYSVNEGPDLGT
NLFTGPYRETNLRTAYQKALASNEIDFVWITDFQRYQPEVDAPTAWLVSPVGVDGKLQGVMALALPPTNL
NQIMNANEKWEAVGMGRSTETYLAGSDNLMRSDSRLFLESPDEYRREALAGGTREDVVNKAMWLGTTVLV
QPVPSAGLRAALRGQSGITKDTDYLGNRELEAYAPLDVPNSDLRWAILATRDDWDAYERLSSFGRTVVLA
VAGITLFICVVSMVLAKLLVRPIRRLEAGTEKIRSGDYEVTVPVKSRDELGDLTAAFNEMSSNLKVKDQL
LTEQRSQNEQLLLALMPEPVVQRYRADGEVIAEEHQDVTVIFAELIGLEEISDGLSGDELVGIVDELFRQ
FDSAAQSLGVEPIRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVNRFANQSQHPLRVRVGVTTGRV
VSGRVGRSNLAYDMWGGAVQMAYRMLGHLSDPGIYVSARVHDAMREIWTFTPAGAISVRGSQQQIWQVSE
RR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3698--100% (703)adenylate or guanylate cyclase
M. ulcerans Agy99MUL_4617-1e-1824.33% (374) hypothetical protein MUL_4617
M. ulcerans Agy99MUL_4221-5e-1223.75% (261) adenylate cyclase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2461c-0.060.69% (697) putative cyclase (adenylyl-or guanylyl-)(adenylate-or
M. gilvum PYR-GCKMflv_3576-6e-2126.96% (204) putative adenylate/guanylate cyclase
M. tuberculosis H37RvRv2435c-0.060.69% (697) cyclase
M. leprae Br4923MLBr_00201-1e-1223.55% (259) hypothetical protein MLBr_00201
M. abscessus ATCC 19977MAB_4523-2e-1225.31% (241) putative adenylate cyclase
M. marinum MMMAR_3755-0.098.72% (703) adenylate or guanylate cyclase
M. avium 104MAV_1745-0.062.27% (697) adenylate and guanylate cyclase catalytic domain-containing
M. smegmatis MC2 155MSMEG_3578-0.051.14% (704) putative cyclase
M. thermoresistible (build 8)TH_2298-0.051.86% (698) PROBABLE CYCLASE (ADENYLYL-OR GUANYLYL-)(ADENYLATE-OR
M. vanbaalenii PYR-1Mvan_2839-2e-2126.87% (201) putative adenylate/guanylate cyclase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2461c|M.bovis_AF2122/97           MTSGEALDSVAESESTPAKKRHKNVLR--RRPRFRASIQSKLMVLLLLTS
Rv2435c|M.tuberculosis_H37Rv        MTSGEALDSVAESESTPAKKRHKNVLR--RRPRFRASIQSKLMVLLLLTS
MUL_3698|M.ulcerans_Agy99           -----------------------------MLRFLRVGIPAKLLVTLLVCS
MMAR_3755|M.marinum_M               MTSGQPTEPVTAAASGQTGRTDSRGRR--LLRFLRVGIQAKLLVTLLVCS
MAV_1745|M.avium_104                MTTSELTDAESDIAPAPAPQPAKRTRRTPLRSRFRFGIQSKILITMLLSS
MSMEG_3578|M.smegmatis_MC2_155      -------------------------------MLSRISIQSKLLAMLLVTS
TH_2298|M.thermoresistible__bu      ---------------------MAIRRKPRRHWTPRFSIQSKLLMMLLTTS
MLBr_00201|M.leprae_Br4923          --------------------------------------------------
MAB_4523|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2461c|M.bovis_AF2122/97           IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLV
Rv2435c|M.tuberculosis_H37Rv        IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLV
MUL_3698|M.ulcerans_Agy99           ILSVAVVGVIGYVSGRNALQRVAVERLHQLREAQKRQVEALFSELTKSVM
MMAR_3755|M.marinum_M               ILSVAVVGVIGYVSGRNALQRVAVERLLQLREAQKRQVEALFSELTKSVM
MAV_1745|M.avium_104                ILGVAVIGLIGAVSGRNALRQVESERLIELREGQKRAVQALFREVTNSLI
MSMEG_3578|M.smegmatis_MC2_155      VLSAAVVGFIGYQSGRSSLRDSVFDRLTEIRTAQARQLETQFRSFRNSLV
TH_2298|M.thermoresistible__bu      VLAVAVVGFIGYQSGRSSLRASAFDGLIEIRTSQARELETLFSDLTNSLV
MLBr_00201|M.leprae_Br4923          ---------------------------------------------MATQA
MAB_4523|M.abscessus_ATCC_1997      ------------------------------------------------MM
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2461c|M.bovis_AF2122/97           IYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT
Rv2435c|M.tuberculosis_H37Rv        IYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT
MUL_3698|M.ulcerans_Agy99           VYSNGMSANEATAALTDGFAQLANATVDPVQQQAIVDYYVNELIKPIDQA
MMAR_3755|M.marinum_M               VYSNGMSANEATAAFTDGFAQLANATVDPVQQQAIVDYYVNELIKPIDQA
MAV_1745|M.avium_104                VWSGGFTINEATAALTTGFAQLANATITPAQQQQLVNYYDNQMLKPIKHA
MSMEG_3578|M.smegmatis_MC2_155      IYTRGTTAIEAARAFTAGFDQLGDATISPAQQKAITDWYENQFSATTEHS
TH_2298|M.thermoresistible__bu      IYSRGDTAAAAVTAFTDAFDELHDATVTPAQHRAIVDYYERHFGGDTTAT
MLBr_00201|M.leprae_Br4923          AGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDR
MAB_4523|M.abscessus_ATCC_1997      ERLREWFRAMHVLGPR--WSVFVASMVGINAATLLLLFYFLRHWMPFKR-
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2461c|M.bovis_AF2122/97           T------GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGS
Rv2435c|M.tuberculosis_H37Rv        T------GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGS
MUL_3698|M.ulcerans_Agy99           T------GHELDLEAVLSASPAQTYLQAYYTAPFSSSSESMRFNNAGDGS
MMAR_3755|M.marinum_M               T------GHELDLEAVLPASPAQTYLQAYYTAPFSSSSESMRFNNAGDGS
MAV_1745|M.avium_104                T------GDSIDINAVLPNSNAQKYVQAYYTAAPRPTPDSLPVQDAGDGS
MSMEG_3578|M.smegmatis_MC2_155      DAADNLDGNEVDVEALLPSSNPQKYLQALYTAPFTDWDKAIENDDAGDGS
TH_2298|M.thermoresistible__bu      -------GSRLRVEALLPSGSAQRYLQAHYTAPFSDWDAAIDNDDAGDGS
MLBr_00201|M.leprae_Br4923          V-------------------------------------------ELQDLP
MAB_4523|M.abscessus_ATCC_1997      --------------------------------------------PAGDWV
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       -----------------------------MRPVCVPEVTLG---RRAWSP
Mb2461c|M.bovis_AF2122/97           AWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILT
Rv2435c|M.tuberculosis_H37Rv        AWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILT
MUL_3698|M.ulcerans_Agy99           AWSAANARFNDFFRGIVTRFQYRDALLLDLQGNVVYSVNEGPDLGTNLFT
MMAR_3755|M.marinum_M               AWSAANARFNDFFRGIVTRFQYRDALLLDLQGNVVYSVNKGPDLGTNLFT
MAV_1745|M.avium_104                AWSAANARFDFYVRDIATRFDYRDALLLDTQGNVVYSVMKGPDLGTNILT
MSMEG_3578|M.smegmatis_MC2_155      GWSAANALFNGFFREIVTRSGFDDALLLDTRGNVVYTAYKGSDLGTNIYT
TH_2298|M.thermoresistible__bu      AWSAANARFHDFFREIVERFEFEDALLIDTRGNVVYSAYKGVDLGTNLHT
MLBr_00201|M.leprae_Br4923          IRN---LAISTLSVVVAFSTGFAVNLKLLMPVFRWQRRDNRLAEADPAAT
MAB_4523|M.abscessus_ATCC_1997      FENGPPLFWLLFGIMIVTSVGWALHMEHRL--ARWYCRG-----GPPTAL
                                                                                      

Mflv_3576|M.gilvum_PYR-GCK          -------MGRRQSVLMIAGWIAAAVSAAFGAFQLTLGGSLWWLGAVNVLC
Mvan_2839|M.vanbaalenii_PYR-1       SRHRHERVARRQRVLMIASWIAAAASVGFGVFQLTFGGPLWWLGAVNIGC
Mb2461c|M.bovis_AF2122/97           GPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAG
Rv2435c|M.tuberculosis_H37Rv        GPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAG
MUL_3698|M.ulcerans_Agy99           GPYRETNLRTAYQKALASNEIDFVWITDFQRYQPEVDAPTAWLVSPVGVD
MMAR_3755|M.marinum_M               GPYRETNLRTAYQKALASNEIDFVWITDFQRYQPEVDAPTAWLVSPVGVD
MAV_1745|M.avium_104                GPYRESKLREAYQKALASNDVDFVWITDFQPYQPQLDAPTAWVVSPVGMN
MSMEG_3578|M.smegmatis_MC2_155      GPYKGGELSEAYREALNSNTVDYVAVTDFGIYQPS-GTPTAWMVSPIGGG
TH_2298|M.thermoresistible__bu      GPYRETALSEAYRKALGSNMVDHVGLTDFSTYQPT-SEPTAWMVSPVGTG
MLBr_00201|M.leprae_Br4923          ELARSRALRMPFYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATAL
MAB_4523|M.abscessus_ATCC_1997      ELR--TALTAPLQQSLLHLGGWAIGATVFIAAGAMHDSKWTLATIIGCVQ
                                           :       :          . *                     

Mflv_3576|M.gilvum_PYR-GCK          ALVFLWIPRLCPLG------------------------------------
Mvan_2839|M.vanbaalenii_PYR-1       GVVFLAIPRLCPLG------------------------------------
Mb2461c|M.bovis_AF2122/97           GKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDS
Rv2435c|M.tuberculosis_H37Rv        GKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDS
MUL_3698|M.ulcerans_Agy99           GKLQGVMALALPPTNLNQIMNANEKWEAVGMGRSTETYLAGSDNLMRSDS
MMAR_3755|M.marinum_M               GKLQGVMALALPPTNLNQIMNANEKWEAVGMGRSTETYLAGSDNLMRSDS
MAV_1745|M.avium_104                GRIEGVMALPVPAAKINKIMTAGGHWEAAGMGPATETYLAGPDDLMRSDS
MSMEG_3578|M.smegmatis_MC2_155      GRIEGVLALQFPISVVNQLMTMDGKWEESGLGETGETYLVGPDGLMRSDS
TH_2298|M.thermoresistible__bu      GRILGALALQFPIDKINRVMTADRQWESVGLGRTGETYLVGTDDLMRSDS
MLBr_00201|M.leprae_Br4923          GATATAIIGYLQSE------------------------------------
MAB_4523|M.abscessus_ATCC_1997      SATASFGITYLLGE------------------------------------
                                    .                                                 

Mflv_3576|M.gilvum_PYR-GCK          ---------------------------------ELLAPLTFVTFAYMSVT
Mvan_2839|M.vanbaalenii_PYR-1       ---------------------------------ELIAPLTFVVFAYTSVG
Mb2461c|M.bovis_AF2122/97           RLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRG
Rv2435c|M.tuberculosis_H37Rv        RLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRG
MUL_3698|M.ulcerans_Agy99           RLFLESPDEYRREALAGGTREDVVNKAMWLGTTVLVQPVPSAGLRAALRG
MMAR_3755|M.marinum_M               RLFLESPDEYRREALAGGTREDVVNKAIRLGTTVLVQPVPSAGLRAALRG
MAV_1745|M.avium_104                RVFVEDPQQYRRDAIDAGTPPDVVDRAIHLGGTTLVQPVATAGLRAAQRG
MSMEG_3578|M.smegmatis_MC2_155      RLFLENPEQFKADVIEAGTPPGVAEQSILHGGTTLVQPVSDEASKLAGQG
TH_2298|M.thermoresistible__bu      RLFLEDPEQFKRAVVEAGTPPTVAEESLRSGGTTLVQPIRNEAVDRAQRG
MLBr_00201|M.leprae_Br4923          ---------------------------------RVLRPVAVAALRSGVPE
MAB_4523|M.abscessus_ATCC_1997      ---------------------------------RILRPIAAKALSASEFH
                                                                      :: *:           

Mflv_3576|M.gilvum_PYR-GCK          FFCYTIGTGSG-----------------MQFYFLVAASLVLLVLGIERVA
Mvan_2839|M.vanbaalenii_PYR-1       FICYTIGTGSG-----------------LQFYFLVAASLVVLVLGIERIA
Mb2461c|M.bovis_AF2122/97           QTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFS
Rv2435c|M.tuberculosis_H37Rv        QTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFS
MUL_3698|M.ulcerans_Agy99           QSGITKDTDYLGNRELEAYAPLDVPNSDLRWAILATRDDWDAYERLSSFG
MMAR_3755|M.marinum_M               QSGITKDTDYLGNRELEAYAPLDVPNSDLRWAILATRDDWDAYERLSSFG
MAV_1745|M.avium_104                ETGVVTATDYMGNRELEAYAPLNIPNSDLHWSILATRDNSDAFARLGRFS
MSMEG_3578|M.smegmatis_MC2_155      QSGSIIERDYLGQETLQAYAPLDLTG--LDWSVVAKIDTAEAFAPVTKFT
TH_2298|M.thermoresistible__bu      QTGTLIGTDYLGREALQSYAPVDLPG--LNWSIVAEKDTAEAFGPVVEFT
MLBr_00201|M.leprae_Br4923          N---VKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFS
MAB_4523|M.abscessus_ATCC_1997      G---RFAPSVFVRVRLSWWIGTLAPAIGIIALCGMALWKPEDLTSTRDLA
                                            .                   :                   . 

Mflv_3576|M.gilvum_PYR-GCK          LAAVIAGVGVVITVVLELTVPEDRGLGPSWTLTAGFISAVTSSAVMIVAT
Mvan_2839|M.vanbaalenii_PYR-1       LAAAIAAAGVIITIVLELTVPDDRGLGPSWTLTAGFISAVVSSVVIIVAT
Mb2461c|M.bovis_AF2122/97           RALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPV
Rv2435c|M.tuberculosis_H37Rv        RALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPV
MUL_3698|M.ulcerans_Agy99           RTVVLAVAGITLFICVVSMVLAKLLVRPIRRLEAGTEKIRSGDYEVTVPV
MMAR_3755|M.marinum_M               RTVVLAVAGITLFICVVSMVLAKLLVRPIRRLEAGTEKIRSGDYEVTVPV
MAV_1745|M.avium_104                KNLVIAVTAMIFVICVASMFVAQAAVRPVRRLEEGTRKISSGDYDINIPV
MSMEG_3578|M.smegmatis_MC2_155      RTLVLSTVAMIFAVCIAAILLARVFVRPIRRLEAGAQQISAGDYGVALPV
TH_2298|M.thermoresistible__bu      RTLVLSTVSIVFAVCLAAMLLARIFVRPVRRLEAGVRRVATGDYHVRLPV
MLBr_00201|M.leprae_Br4923          PILLLALAVLVVG-LVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQI
MAB_4523|M.abscessus_ATCC_1997      LTVLLIVSTTLVGSYGLALLTAGQLADPVRQLRTAISDVAQGDFNARVEV
                                        :      .       .       *   *  .      ..    :  

Mflv_3576|M.gilvum_PYR-GCK          IWYT------------LREIERAESAMENEYERSERLLANILPATIAERL
Mvan_2839|M.vanbaalenii_PYR-1       IWYT------------LREIDRAEAAMAAEYERSEELLANILPATIADRL
Mb2461c|M.bovis_AF2122/97           KSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERY
Rv2435c|M.tuberculosis_H37Rv        KSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERY
MUL_3698|M.ulcerans_Agy99           KSRDELGDLTAAFNEMSSNLKVKDQLLTEQRSQNEQLLLALMPEPVVQRY
MMAR_3755|M.marinum_M               KSRDELGDLTAAFNEMSSNLKVKDQLLTEQRSQNEQLLLALMPEPVVQRY
MAV_1745|M.avium_104                RARDEIGDLTAAFNEMSRNLAIKEELLNEQRRENDRLLLALMPESVLQRY
MSMEG_3578|M.smegmatis_MC2_155      VSRDEFGDLTVAFNEMSRNLRIKEDLLDEQRKENDRLLLSLMPEPVVQRY
TH_2298|M.thermoresistible__bu      TSHDEFGDLTAAFNDMSRNLATKEELLAEQRRENDRLLLSLMPEPVVQRY
MLBr_00201|M.leprae_Br4923          YDASELGLLQAGFNDMVREL--------SERQRLRDLFGRYVGEDVARRA
MAB_4523|M.abscessus_ATCC_1997      YDGSELGVLQAGFNRMMQVG--------EERRQLRELFGKHVGADVASQA
                                                                 :  .   *:   :   :  : 

Mflv_3576|M.gilvum_PYR-GCK          KEPTRTVIADKYDDASILFADIAGYTKRASDTAPAELVRFLDLLYTDLDA
Mvan_2839|M.vanbaalenii_PYR-1       KEPTRTVIADKYDDASILFADIAGYTKRASETPPSELVRFLDRLYTDLDA
Mb2461c|M.bovis_AF2122/97           RL-GEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDS
Rv2435c|M.tuberculosis_H37Rv        RL-GEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDS
MUL_3698|M.ulcerans_Agy99           RA-DGEVIAEEHQDVTVIFAELIGLEEISDGLSGDELVGIVDELFRQFDS
MMAR_3755|M.marinum_M               RA-GGEVIAEEHQDVTVIFAELIGLEEISDGLSGDELVGIVDELFRQFDS
MAV_1745|M.avium_104                RE-GEETIAQKHQDVAIIYADIVGLDELFTEMPEAQLVGTVDELFRQFDS
MSMEG_3578|M.smegmatis_MC2_155      RE-GEETIAQDHQNVTVLFADLMGLDRLSASMSSDEHLSIVNKLVRQFDA
TH_2298|M.thermoresistible__bu      RD-GEQTIAQDHQDVTVIFADIVGLDEVSFNLPSAEAVPIVNELIRQFDA
MLBr_00201|M.leprae_Br4923          LE-HGTELGGQERDVAVLFVDLIGSTQLAETKPPTKVVHLLNEFFRVVVD
MAB_4523|M.abscessus_ATCC_1997      LQ-LGTNLGGENRYVAVFFVDMIGSTSMAADRDPEEVLTILNDFFRIVVE
                                           :. .   .::::.:: *           : :  :: :   .  

Mflv_3576|M.gilvum_PYR-GCK          LVDRHGLEKVKTSGDSYMVVSGVPTPRPDHLEALATLALDMSEAVADLKD
Mvan_2839|M.vanbaalenii_PYR-1       LVDRHGLEKVKTSGDSYMVVSGVPNPRADHLEALALLALDMADAVADLKD
Mb2461c|M.bovis_AF2122/97           AAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNC
Rv2435c|M.tuberculosis_H37Rv        AAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNC
MUL_3698|M.ulcerans_Agy99           AAQSLGVEPIRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVNRFAN
MMAR_3755|M.marinum_M               AAQSLGVEPIRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVNRFAN
MAV_1745|M.avium_104                AAETLGVERIRTFHNGYLASCGVVTPRLDSIHRAVDFALEIGRIIDRFNS
MSMEG_3578|M.smegmatis_MC2_155      AAESLGVERVRTLHNGYLASCGLTVPRLDNVRRTVDFAFEMQRIVDRFRG
TH_2298|M.thermoresistible__bu      AADHHGVERVRTMHNGYIASCGLSVPRLDNVRRTVDFALDLQRIIDRFTR
MLBr_00201|M.leprae_Br4923          TVGRHGGFVNKFQGDAALAIFGAPIEHPDSAGAALSAARELH---DELLP
MAB_4523|M.abscessus_ATCC_1997      VVDSRGGFVNKFVGDEALSVFGAPLHRPDATTACLAAARELR---DRLNE
                                     .   *    :   :  :   *    : *        * ::      :  

Mflv_3576|M.gilvum_PYR-GCK          PRGRDVPLRIGMAMGPVVAGVVGAKK-FFYDVWGDAVNVASRMETTDEEG
Mvan_2839|M.vanbaalenii_PYR-1       PQGHDVPLRIGMASGPVVAGVVGAKK-FFYDVWGDAVNVASRMETTDVEG
Mb2461c|M.bovis_AF2122/97           QTGNDLHLRVGINTGDVISGLVGRSS-VVYDMWGAAVSLAYQMHSGSPQP
Rv2435c|M.tuberculosis_H37Rv        QTGNDLHLRVGINTGDVISGLVGRSS-VVYDMWGAAVSLAYQMHSGSPQP
MUL_3698|M.ulcerans_Agy99           QSQHPLRVRVGVTTGRVVSGRVGRSN-LAYDMWGGAVQMAYRMLGHLSDP
MMAR_3755|M.marinum_M               QSQHPLRVRVGVTTGRVVSGLVGRSN-LAYDMWGGAVQMAYRMLGHLSDP
MAV_1745|M.avium_104                QTGHQLGLRIGVNTGNVVSGLVGRSG-LVYDMWGGAVSLAYQMHSGSPQP
MSMEG_3578|M.smegmatis_MC2_155      ETGYDLRLRAGIDTGTVSSGLVGRSS-LAYDMWGAAVDLAYQVQRGMPQP
TH_2298|M.thermoresistible__bu      ETGHRLELRAGIDTGTVKSGLVDRSR-LAYDMWGSAVNIAYQVQTGTAKP
MLBr_00201|M.leprae_Br4923          VLGS-AEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE
MAB_4523|M.abscessus_ATCC_1997      DFPHPFEFAIGVSAGLAVAGNVGATARYEYSVIGDPVNEASRLTELAKHR
                                           .  *:  * . :* :.      * : * .*. * ::       

Mflv_3576|M.gilvum_PYR-GCK          R----IQVPDNVYQRLRHAFVLEERGLIDVKGKGPMHTWYLVGHRARAVT
Mvan_2839|M.vanbaalenii_PYR-1       R----IQVPDNVYERLRDRFVLEERGVVDVKGKGPMHTWYLVAHRAEAVT
Mb2461c|M.bovis_AF2122/97           G----IYVTSQVYEAMRDVWQFTAAGTISVGGL-EEPIYRLSERS-----
Rv2435c|M.tuberculosis_H37Rv        G----IYVTSQVYEAMRDVWQFTAAGTISVGGL-EEPIYRLSERS-----
MUL_3698|M.ulcerans_Agy99           G----IYVSARVHDAMREIWTFTPAGAISVRGS-QQQIWQVSERR-----
MMAR_3755|M.marinum_M               G----IYVSARVHDAMREIWTFTPAGAISVRGS-QQQIWQVSERR-----
MAV_1745|M.avium_104                G----IYVSSQVYEAMRDVRQFAPAGTISVGGT-DQAIYRLLER------
MSMEG_3578|M.smegmatis_MC2_155      G----VYVTDQVHDAVRDIRQFTAVGSVTVDGT-ERPIWRLSERQS----
TH_2298|M.thermoresistible__bu      G----IFVTTRVRDVLRDTYRFEQAGQIDIDGA-AEPVWRLTEQRS----
MLBr_00201|M.leprae_Br4923          DGHVLASAIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQ
MAB_4523|M.abscessus_ATCC_1997      PSRLLASTNALYFADPDEQKHWEHGDSVLLRGRTRATHLAWPAGT-----
                                           .         .         : : *                  

Mflv_3576|M.gilvum_PYR-GCK          PSSSPP-
Mvan_2839|M.vanbaalenii_PYR-1       PSGSPT-
Mb2461c|M.bovis_AF2122/97           -------
Rv2435c|M.tuberculosis_H37Rv        -------
MUL_3698|M.ulcerans_Agy99           -------
MMAR_3755|M.marinum_M               -------
MAV_1745|M.avium_104                -------
MSMEG_3578|M.smegmatis_MC2_155      -------
TH_2298|M.thermoresistible__bu      -------
MLBr_00201|M.leprae_Br4923          ITSEVTG
MAB_4523|M.abscessus_ATCC_1997      -------