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M. vanbaalenii PYR-1 Mvan_2839 (-)

annotation: putative adenylate/guanylate cyclase
coordinates: 3011731 - 3012996
length: 421

RPVCVPEVTLGRRAWSPSRHRHERVARRQRVLMIASWIAAAASVGFGVFQLTFGGPLWWLGAVNIGCGVV
FLAIPRLCPLGELIAPLTFVVFAYTSVGFICYTIGTGSGLQFYFLVAASLVVLVLGIERIALAAAIAAAG
VIITIVLELTVPDDRGLGPSWTLTAGFISAVVSSVVIIVATIWYTLREIDRAEAAMAAEYERSEELLANI
LPATIADRLKEPTRTVIADKYDDASILFADIAGYTKRASETPPSELVRFLDRLYTDLDALVDRHGLEKVK
TSGDSYMVVSGVPNPRADHLEALALLALDMADAVADLKDPQGHDVPLRIGMASGPVVAGVVGAKKFFYDV
WGDAVNVASRMETTDVEGRIQVPDNVYERLRDRFVLEERGVVDVKGKGPMHTWYLVAHRAEAVTPSGSPT
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2839--100% (421)putative adenylate/guanylate cyclase
M. vanbaalenii PYR-1Mvan_1904-4e-1331.43% (140) adenylyl cyclase class-3/4/guanylyl cyclase
M. vanbaalenii PYR-1Mvan_4309-5e-1332.93% (164) putative adenylate/guanylate cyclase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1651ccya1e-13558.00% (400) membrane-anchored adenylyl cyclase Cya (ATP
M. gilvum PYR-GCKMflv_3576-0.085.32% (395) putative adenylate/guanylate cyclase
M. tuberculosis H37RvRv1625ccya1e-13657.77% (412) membrane-anchored adenylyl cyclase Cya (ATP
M. leprae Br4923MLBr_02341-3e-1527.49% (171) putative regulatory protein
M. abscessus ATCC 19977MAB_1459c-4e-1328.19% (259) hypothetical protein MAB_1459c
M. marinum MMMAR_2428cya1e-12856.89% (392) membrane-anchored adenylyl cyclase Cya
M. avium 104MAV_3162-1e-12554.13% (412) adenylate cyclase
M. smegmatis MC2 155MSMEG_3578-5e-2226.67% (210) putative cyclase
M. thermoresistible (build 8)TH_2942-1e-15770.69% (389) PUTATIVE adenylate cyclase
M. ulcerans Agy99MUL_3698-9e-2226.87% (201) adenylate or guanylate cyclase

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
TH_2942|M.thermoresistible__bu      --------------------------------------------------
Mb1651c|M.bovis_AF2122/97           --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2428|M.marinum_M               --------------------------------------------------
MAV_3162|M.avium_104                --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      --MLSRISIQSKLLAMLLVTSVLSAAVVGFIGYQSGRSSLRDSVFDRLTE
MUL_3698|M.ulcerans_Agy99           MLRFLRVGIPAKLLVTLLVCSILSVAVVGVIGYVSGRNALQRVAVERLHQ
MAB_1459c|M.abscessus_ATCC_199      -----------MANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLG
MLBr_02341|M.leprae_Br4923          -MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVG
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       ----------------------------------------MRPVCVPEVT
Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
TH_2942|M.thermoresistible__bu      -------------------------------------------------V
Mb1651c|M.bovis_AF2122/97           --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv        -----------------------MA--ARKCGAPPIAADGSTRRPDCVTA
MMAR_2428|M.marinum_M               -------------------MPAKKS--AKKCRTARRSSDG-LPRPDSVAA
MAV_3162|M.avium_104                -----------------------MA--AKSCGAAPLWPTGSSKRPDCVAA
MSMEG_3578|M.smegmatis_MC2_155      IRTAQARQLETQFRSFRNSLVIYTR--GTTAIEAARAFTAGFDQLGDATI
MUL_3698|M.ulcerans_Agy99           LREAQKRQVEALFSELTKSVMVYSN--GMSANEATAALTDGFAQLANATV
MAB_1459c|M.abscessus_ATCC_199      TADESTFIQRIRIQLILTVFVVAAN--LIGIGVVILLVTVAFPTPNVFDA
MLBr_02341|M.leprae_Br4923          SMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAP
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       LGRRAWSPSRHRHER------------------------VARRQRVLMIA
Mflv_3576|M.gilvum_PYR-GCK          ---------------------------------------MGRRQSVLMIA
TH_2942|M.thermoresistible__bu      ARQGVPARTQRYAES------------------------IRSRYRMLTIA
Mb1651c|M.bovis_AF2122/97           MRTQARAPTQHYAES------------------------VARRQRVLTIT
Rv1625c|M.tuberculosis_H37Rv        VRTQARAPTQHYAES------------------------VARRQRVLTIT
MMAR_2428|M.marinum_M               VREQTRDLNQHYAHS------------------------AARRARVLSIA
MAV_3162|M.avium_104                ARAQSRARNQHYADS------------------------AARQSRVLAIA
MSMEG_3578|M.smegmatis_MC2_155      SPAQQKAITDWYENQFSATTEHSDAADNLDGNEVDVEALLPSSNPQKYLQ
MUL_3698|M.ulcerans_Agy99           DPVQQQAIVDYYVN------ELIKPIDQATGHELDLEAVLSASPAQTYLQ
MAB_1459c|M.abscessus_ATCC_199      PAWVNFVIVPVYIALAVLIG-------------------AVWGTRRIFKA
MLBr_02341|M.leprae_Br4923          TALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVG
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       SWIAAAASVGFGVFQLTFGGPLWWLGAVN--IGCGVVFLAIPRLCPLGEL
Mflv_3576|M.gilvum_PYR-GCK          GWIAAAVSAAFGAFQLTLGGSLWWLGAVN--VLCALVFLWIPRLCPLGEL
TH_2942|M.thermoresistible__bu      AWIAAAVSAGFGTLQLVLGGQTRLLGVIN--LAVAVVFTLIPLLYRFGEL
Mb1651c|M.bovis_AF2122/97           AWLAVVVTGSFALMQLATGAGGWYIALIN--VFTAVTFAIVPLLHRFGGL
Rv1625c|M.tuberculosis_H37Rv        AWLAVVVTGSFALMQLATGAGGWYIALIN--VFTAVTFAIVPLLHRFGGL
MMAR_2428|M.marinum_M               ALLAVLISSSFILVQFLTQAWIWQITLIN--IAATLVFATVPMLHRFGEL
MAV_3162|M.avium_104                AWLAVLVCADFILLQVVTGAWTWQIVSLN--VVAALIFAIVPWLHRFGDL
MSMEG_3578|M.smegmatis_MC2_155      ALYTAPFTDWDKAIENDDAGDGSGWSAAN--ALFNGFFREIVTRSGFDDA
MUL_3698|M.ulcerans_Agy99           AYYTAPFSSSSESMRFNNAGDGSAWSAAN--ARFNDFFRGIVTRFQYRDA
MAB_1459c|M.abscessus_ATCC_199      VRWALDERPPTKADQRNAFAVPWRLTVIQSVLWAGGVALFTLLYGLYDPM
MLBr_02341|M.leprae_Br4923          EIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAP
                                       :          .                                   

Mvan_2839|M.vanbaalenii_PYR-1       IAPLTFVVFAYTS-------------------------------------
Mflv_3576|M.gilvum_PYR-GCK          LAPLTFVTFAYMS-------------------------------------
TH_2942|M.thermoresistible__bu      LAPLSFFLFAYLS-------------------------------------
Mb1651c|M.bovis_AF2122/97           VAPLTFIGTAYVA-------------------------------------
Rv1625c|M.tuberculosis_H37Rv        VAPLTFIGTAYVA-------------------------------------
MMAR_2428|M.marinum_M               VAPLTFVGAAYVS-------------------------------------
MAV_3162|M.avium_104                VAPLTFLGAAYVT-------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      LLLDTRGNVVYTAYKGSDLGTNIYTGPYKGGELSEAYREALNSNTVDYVA
MUL_3698|M.ulcerans_Agy99           LLLDLQGNVVYSVNEGPDLGTNLFTGPYRETNLRTAYQKALASNEIDFVW
MAB_1459c|M.abscessus_ATCC_199      YIPKIFFAVGFSG------------------------------------A
MLBr_02341|M.leprae_Br4923          QTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVG-----REWELATLA
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       --------------VGFICYTIGTGSGLQ--FYFLVAASLVVLVLGIERI
Mflv_3576|M.gilvum_PYR-GCK          --------------VTFFCYTIGTGSGMQ--FYFLVAASLVLLVLGIERV
TH_2942|M.thermoresistible__bu      --------------VGFMCFSIGTGSGLQ--LYLLVAASLVVLLLGVDRI
Mb1651c|M.bovis_AF2122/97           --------------IFAIGWDVGTDAGAQ--FFFLVAAALVVLLVGIEHT
Rv1625c|M.tuberculosis_H37Rv        --------------IFAIGWDVGTDAGAQ--FFFLVAAALVVLLVGIEHT
MMAR_2428|M.marinum_M               --------------VFASCWNVGTGSGAQ--MFFLVGACLVVLVLGIEHV
MAV_3162|M.avium_104                --------------VFVSCWDVGTASGGQ--YFFLVGACLVLLVMGIEHT
MSMEG_3578|M.smegmatis_MC2_155      VTDFGIYQPS-GTPTAWMVSPIGGGGRIEGVLALQFPISVVNQLMTMDGK
MUL_3698|M.ulcerans_Agy99           ITDFQRYQPEVDAPTAWLVSPVGVDGKLQGVMALALPPTNLNQIMNANEK
MAB_1459c|M.abscessus_ATCC_199      VVCAANYLFTEFAMRPVAARALEAGYRRRRLASGVMVRTVLAWMLGSGVP
MLBr_02341|M.leprae_Br4923          AMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESH
                                                         :                      :     

Mvan_2839|M.vanbaalenii_PYR-1       ALAAAIAAAGVIITIVLELTVPDDRGLGP---------------------
Mflv_3576|M.gilvum_PYR-GCK          ALAAVIAGVGVVITVVLELTVPEDRGLGP---------------------
TH_2942|M.thermoresistible__bu      VLAAGIVAVGVVGIIVLELVVPEDRGLGP---------------------
Mb1651c|M.bovis_AF2122/97           ALAVGLAAVAAGLVIALEFLVPPDTGLQP---------------------
Rv1625c|M.tuberculosis_H37Rv        ALAVGLAAVAAGLVIALEFLVPPDTGLQP---------------------
MMAR_2428|M.marinum_M               VLASGLAALAAALIITVEFVVPRNTGAQS---------------------
MAV_3162|M.avium_104                VLAAVLAAIGAGLVIAVEFAFPRDTGLQP---------------------
MSMEG_3578|M.smegmatis_MC2_155      WEESGLGETGETYLVGPDGLMRSDSRLFLENPEQFKADVIEAGTPPGVAE
MUL_3698|M.ulcerans_Agy99           WEAVGMGRSTETYLAGSDNLMRSDSRLFLESPDEYRREALAGGTREDVVN
MAB_1459c|M.abscessus_ATCC_199      AAGIVITGIGALVLHNLTVSQLAVAVIIIAGAIPSFG-------------
MLBr_02341|M.leprae_Br4923          ATDVAFDVVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLL
                                         :                                            

Mvan_2839|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_3576|M.gilvum_PYR-GCK          --------------------------------------------------
TH_2942|M.thermoresistible__bu      --------------------------------------------------
Mb1651c|M.bovis_AF2122/97           --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2428|M.marinum_M               --------------------------------------------------
MAV_3162|M.avium_104                --------------------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      QSILHGGTTLVQPVSDEASKLAGQGQSGSIIERDYLGQETLQAYAPLDLT
MUL_3698|M.ulcerans_Agy99           KAMWLGTTVLVQPVPSAGLRAALRGQSGITKDTDYLGNRELEAYAPLDVP
MAB_1459c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02341|M.leprae_Br4923          G-------------------------IADPAVELPRLDPDARRRRLTALI
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       ------------------------SWTLTAGFISAVVSSVVIIVATIWYT
Mflv_3576|M.gilvum_PYR-GCK          ------------------------SWTLTAGFISAVTSSAVMIVATIWYT
TH_2942|M.thermoresistible__bu      ------------------------AWMLTAGFVTSAVSSALIIFATLWYA
Mb1651c|M.bovis_AF2122/97           ------------------------PWAMSVSFVLTTVSACGVAVATVWFA
Rv1625c|M.tuberculosis_H37Rv        ------------------------PWAMSVSFVLTTVSACGVAVATVWFA
MMAR_2428|M.marinum_M               ------------------------AWLQSLGFIITTVSACLLVFVTVWFA
MAV_3162|M.avium_104                ------------------------AWAQSMSFVVTIVSACIMVFVAVWFA
MSMEG_3578|M.smegmatis_MC2_155      G--LDWSVVAKIDTAEAFAPVTKFTRTLVLSTVAMIFAVCIAAILLARVF
MUL_3698|M.ulcerans_Agy99           NSDLRWAILATRDDWDAYERLSSFGRTVVLAVAGITLFICVVSMVLAKLL
MAB_1459c|M.abscessus_ATCC_199      -----------------LILIWIASWLMATPVKEVQTAIKRVAQNDLDID
MLBr_02341|M.leprae_Br4923          NVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPE
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       LREIDRAEA-----------------------------------------
Mflv_3576|M.gilvum_PYR-GCK          LREIERAES-----------------------------------------
TH_2942|M.thermoresistible__bu      LREIARTEA-----------------------------------------
Mb1651c|M.bovis_AF2122/97           LRDTARAEA-----------------------------------------
Rv1625c|M.tuberculosis_H37Rv        LRDTARAEA-----------------------------------------
MMAR_2428|M.marinum_M               LRDTARAEA-----------------------------------------
MAV_3162|M.avium_104                LRDTQRAEA-----------------------------------------
MSMEG_3578|M.smegmatis_MC2_155      VRPIRRLEAGAQQISAGDYGVALPVVSRDEFGDLTVAFNEMSRNLRIKED
MUL_3698|M.ulcerans_Agy99           VRPIRRLEAGTEKIRSGDYEVTVPVKSRDELGDLTAAFNEMSSNLKVKDQ
MAB_1459c|M.abscessus_ATCC_199      LVVYDGTELGELQAGFN------------------------------TMV
MLBr_02341|M.leprae_Br4923          YHGALRHVVGAQIIAVAPLSDVETSTLVAELLG--------LDQSVTQIG
                                                                                      

Mvan_2839|M.vanbaalenii_PYR-1       AMAAEYERSEELLANILPATIADR--------------------LKEPTR
Mflv_3576|M.gilvum_PYR-GCK          AMENEYERSERLLANILPATIAER--------------------LKEPTR
TH_2942|M.thermoresistible__bu      AMEAEYQRSESLLLNILPASVARR--------------------LKDPAR
Mb1651c|M.bovis_AF2122/97           VMEAEHDRSEALLANMLPASIAER--------------------LKEPER
Rv1625c|M.tuberculosis_H37Rv        VMEAEHDRSEALLANMLPASIAER--------------------LKEPER
MMAR_2428|M.marinum_M               VMEAQYDRSEALLANMLPVSVADR--------------------LKEPER
MAV_3162|M.avium_104                VMESEYQRSEALLANMLPGSIAER--------------------LKHSDG
MSMEG_3578|M.smegmatis_MC2_155      LLDEQRKENDRLLLSLMPEPVVQR--------------------YRE-GE
MUL_3698|M.ulcerans_Agy99           LLTEQRSQNEQLLLALMPEPVVQR--------------------YRA-DG
MAB_1459c|M.abscessus_ATCC_199      EGLRERERVRDLFGKHVGREVAAA--------------------AEQ-QQ
MLBr_02341|M.leprae_Br4923          ELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQ
                                        :      ::   :   :.                            

Mvan_2839|M.vanbaalenii_PYR-1       TVIADKYDDASILFADIAGYTKRASETPPSELVRFLDRLYTDLDALVDRH
Mflv_3576|M.gilvum_PYR-GCK          TVIADKYDDASILFADIAGYTKRASDTAPAELVRFLDLLYTDLDALVDRH
TH_2942|M.thermoresistible__bu      TVIADKYDDASVLFADIAGYTRWAGATTPSELVLFLDRLYTELDALVDRH
Mb1651c|M.bovis_AF2122/97           NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQH
Rv1625c|M.tuberculosis_H37Rv        NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQH
MMAR_2428|M.marinum_M               NIIADKYEEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDALVDKY
MAV_3162|M.avium_104                DIIADKYDDASVLFADIVGFTERASGTAPADLVRFLNRLYIAFDELVDKH
MSMEG_3578|M.smegmatis_MC2_155      ETIAQDHQNVTVLFADLMGLDRLSASMSSDEHLSIVNKLVRQFDAAAESL
MUL_3698|M.ulcerans_Agy99           EVIAEEHQDVTVIFAELIGLEEISDGLSGDELVGIVDELFRQFDSAAQSL
MAB_1459c|M.abscessus_ATCC_199      PELGGEERHIAVLFADIVGSTRLAATRPAVEVVALLNRFFTVVVEEIDRY
MLBr_02341|M.leprae_Br4923          ATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG-IDLSVDELIDAN
                                      :.      :    ::             : :  :. :   .    :  

Mvan_2839|M.vanbaalenii_PYR-1       GLEKVKTSGDSYMVVSGVPNPRADHLEALALLALDMADAVADLKDPQGHD
Mflv_3576|M.gilvum_PYR-GCK          GLEKVKTSGDSYMVVSGVPTPRPDHLEALATLALDMSEAVADLKDPRGRD
TH_2942|M.thermoresistible__bu      GLEKVKTSGDSYMVVSGVPQPRPDHLEALADFALDMAAAVGRLRDPQGRT
Mb1651c|M.bovis_AF2122/97           GLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNP
Rv1625c|M.tuberculosis_H37Rv        GLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNP
MMAR_2428|M.marinum_M               GLEKIKVSGDSYMVVSGVPRPRPDHVQALADFALDMVDVAAGMKDPHNRS
MAV_3162|M.avium_104                GLEKIKVSGDSYMVVSGVPRVRPDHATALADFALDMVKVAAALKDPYGRP
MSMEG_3578|M.smegmatis_MC2_155      GVERVRTLHNGYLASCGLTVPRLDNVRRTVDFAFEMQRIVDRFRGETGYD
MUL_3698|M.ulcerans_Agy99           GVEPIRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVNRFANQSQHP
MAB_1459c|M.abscessus_ATCC_199      EGMVNKFEGDATLAVFGAPVRQ----DRPESQALAAARAIARRLRTEVPE
MLBr_02341|M.leprae_Br4923          LVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPH
                                         :       .                                    

Mvan_2839|M.vanbaalenii_PYR-1       --VPLRIGMASGPVVAGVVGAKK-FFYDVWGDAVNVASRMETTDVEGRIQ
Mflv_3576|M.gilvum_PYR-GCK          --VPLRIGMAMGPVVAGVVGAKK-FFYDVWGDAVNVASRMETTDEEGRIQ
TH_2942|M.thermoresistible__bu      --VPLRIGLAAGPVVAGVVGARK-FFYDVWGDAVNVGSRMESTDVVGRIQ
Mb1651c|M.bovis_AF2122/97           --VPLRVGLATGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGQIQ
Rv1625c|M.tuberculosis_H37Rv        --VPLRVGLATGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGQIQ
MMAR_2428|M.marinum_M               --VPLRVGLATGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGKIQ
MAV_3162|M.avium_104                --VPLRVGMACGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGRIQ
MSMEG_3578|M.smegmatis_MC2_155      --LRLRAGIDTGTVSSGLVGRSS-LAYDMWGAAVDLAYQVQRGMPQPGVY
MUL_3698|M.ulcerans_Agy99           --LRVRVGVTTGRVVSGRVGRSN-LAYDMWGGAVQMAYRMLGHLSDPGIY
MAB_1459c|M.abscessus_ATCC_199      --CQAGIGVASGQAVAGNIGAHDRFEYTVIGDPVNEAARLCELSKT----
MLBr_02341|M.leprae_Br4923          SVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK
                                            :      :* :           . ..:   :           

Mvan_2839|M.vanbaalenii_PYR-1       VPDNVYERLRDRFVLEERGVVDVKGKGPMHTWYLVAHR------------
Mflv_3576|M.gilvum_PYR-GCK          VPDNVYQRLRHAFVLEERGLIDVKGKGPMHTWYLVGHR------------
TH_2942|M.thermoresistible__bu      VAQDVRDRLRDSFVFEERGAIEVKGKGVMHTWYLLGRRSDRQGSDRQGSG
Mb1651c|M.bovis_AF2122/97           VPDEVYERLKDDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGE-----
Rv1625c|M.tuberculosis_H37Rv        VPDEVYERLKDDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGE-----
MMAR_2428|M.marinum_M               VPDEVYERLNKDFVLQERGHINVKGKGVMRTWYLIGRKPIDEPTA-----
MAV_3162|M.avium_104                VPETMYERLASEFVLQERGRIEVKGKGVMRTWYLIGRKPAEAPTD-----
MSMEG_3578|M.smegmatis_MC2_155      VTDQVHDAVRDIRQFTAVGSVTVDGTE-RPIWRLSERQS-----------
MUL_3698|M.ulcerans_Agy99           VSARVHDAMREIWTFTPAGAISVRGSQ-QQIWQVSERR------------
MAB_1459c|M.abscessus_ATCC_199      VPGHLVASLDTVLRAHHREALHWRSGDTVTLRGRTEPTELAVPV------
MLBr_02341|M.leprae_Br4923          IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCN----
                                    :.  :                   .                         

Mvan_2839|M.vanbaalenii_PYR-1       --------------AEAVTPSGSPT------
Mflv_3576|M.gilvum_PYR-GCK          --------------ARAVTPSSSPP------
TH_2942|M.thermoresistible__bu      RQGSGRQGSGRQGGTEASTAARTHG------
Mb1651c|M.bovis_AF2122/97           --------------VRGAEPRTAGV------
Rv1625c|M.tuberculosis_H37Rv        --------------VRGAEPRTAGV------
MMAR_2428|M.marinum_M               --------------VPADEPNAARV------
MAV_3162|M.avium_104                --------------LVAEQPHTAHV------
MSMEG_3578|M.smegmatis_MC2_155      -------------------------------
MUL_3698|M.ulcerans_Agy99           -------------------------------
MAB_1459c|M.abscessus_ATCC_199      -------------------------------
MLBr_02341|M.leprae_Br4923          -----ATGDKAPLAVATVGPAIDHVYQDRLH