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RPVCVPEVTLGRRAWSPSRHRHERVARRQRVLMIASWIAAAASVGFGVFQLTFGGPLWWLGAVNIGCGVV FLAIPRLCPLGELIAPLTFVVFAYTSVGFICYTIGTGSGLQFYFLVAASLVVLVLGIERIALAAAIAAAG VIITIVLELTVPDDRGLGPSWTLTAGFISAVVSSVVIIVATIWYTLREIDRAEAAMAAEYERSEELLANI LPATIADRLKEPTRTVIADKYDDASILFADIAGYTKRASETPPSELVRFLDRLYTDLDALVDRHGLEKVK TSGDSYMVVSGVPNPRADHLEALALLALDMADAVADLKDPQGHDVPLRIGMASGPVVAGVVGAKKFFYDV WGDAVNVASRMETTDVEGRIQVPDNVYERLRDRFVLEERGVVDVKGKGPMHTWYLVAHRAEAVTPSGSPT *
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2839 | - | - | 100% (421) | putative adenylate/guanylate cyclase |
M. vanbaalenii PYR-1 | Mvan_1904 | - | 4e-13 | 31.43% (140) | adenylyl cyclase class-3/4/guanylyl cyclase |
M. vanbaalenii PYR-1 | Mvan_4309 | - | 5e-13 | 32.93% (164) | putative adenylate/guanylate cyclase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1651c | cya | 1e-135 | 58.00% (400) | membrane-anchored adenylyl cyclase Cya (ATP |
M. gilvum PYR-GCK | Mflv_3576 | - | 0.0 | 85.32% (395) | putative adenylate/guanylate cyclase |
M. tuberculosis H37Rv | Rv1625c | cya | 1e-136 | 57.77% (412) | membrane-anchored adenylyl cyclase Cya (ATP |
M. leprae Br4923 | MLBr_02341 | - | 3e-15 | 27.49% (171) | putative regulatory protein |
M. abscessus ATCC 19977 | MAB_1459c | - | 4e-13 | 28.19% (259) | hypothetical protein MAB_1459c |
M. marinum M | MMAR_2428 | cya | 1e-128 | 56.89% (392) | membrane-anchored adenylyl cyclase Cya |
M. avium 104 | MAV_3162 | - | 1e-125 | 54.13% (412) | adenylate cyclase |
M. smegmatis MC2 155 | MSMEG_3578 | - | 5e-22 | 26.67% (210) | putative cyclase |
M. thermoresistible (build 8) | TH_2942 | - | 1e-157 | 70.69% (389) | PUTATIVE adenylate cyclase |
M. ulcerans Agy99 | MUL_3698 | - | 9e-22 | 26.87% (201) | adenylate or guanylate cyclase |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_2839|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3576|M.gilvum_PYR-GCK -------------------------------------------------- TH_2942|M.thermoresistible__bu -------------------------------------------------- Mb1651c|M.bovis_AF2122/97 -------------------------------------------------- Rv1625c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2428|M.marinum_M -------------------------------------------------- MAV_3162|M.avium_104 -------------------------------------------------- MSMEG_3578|M.smegmatis_MC2_155 --MLSRISIQSKLLAMLLVTSVLSAAVVGFIGYQSGRSSLRDSVFDRLTE MUL_3698|M.ulcerans_Agy99 MLRFLRVGIPAKLLVTLLVCSILSVAVVGVIGYVSGRNALQRVAVERLHQ MAB_1459c|M.abscessus_ATCC_199 -----------MANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLG MLBr_02341|M.leprae_Br4923 -MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVG Mvan_2839|M.vanbaalenii_PYR-1 ----------------------------------------MRPVCVPEVT Mflv_3576|M.gilvum_PYR-GCK -------------------------------------------------- TH_2942|M.thermoresistible__bu -------------------------------------------------V Mb1651c|M.bovis_AF2122/97 -------------------------------------------------- Rv1625c|M.tuberculosis_H37Rv -----------------------MA--ARKCGAPPIAADGSTRRPDCVTA MMAR_2428|M.marinum_M -------------------MPAKKS--AKKCRTARRSSDG-LPRPDSVAA MAV_3162|M.avium_104 -----------------------MA--AKSCGAAPLWPTGSSKRPDCVAA MSMEG_3578|M.smegmatis_MC2_155 IRTAQARQLETQFRSFRNSLVIYTR--GTTAIEAARAFTAGFDQLGDATI MUL_3698|M.ulcerans_Agy99 LREAQKRQVEALFSELTKSVMVYSN--GMSANEATAALTDGFAQLANATV MAB_1459c|M.abscessus_ATCC_199 TADESTFIQRIRIQLILTVFVVAAN--LIGIGVVILLVTVAFPTPNVFDA MLBr_02341|M.leprae_Br4923 SMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAP Mvan_2839|M.vanbaalenii_PYR-1 LGRRAWSPSRHRHER------------------------VARRQRVLMIA Mflv_3576|M.gilvum_PYR-GCK ---------------------------------------MGRRQSVLMIA TH_2942|M.thermoresistible__bu ARQGVPARTQRYAES------------------------IRSRYRMLTIA Mb1651c|M.bovis_AF2122/97 MRTQARAPTQHYAES------------------------VARRQRVLTIT Rv1625c|M.tuberculosis_H37Rv VRTQARAPTQHYAES------------------------VARRQRVLTIT MMAR_2428|M.marinum_M VREQTRDLNQHYAHS------------------------AARRARVLSIA MAV_3162|M.avium_104 ARAQSRARNQHYADS------------------------AARQSRVLAIA MSMEG_3578|M.smegmatis_MC2_155 SPAQQKAITDWYENQFSATTEHSDAADNLDGNEVDVEALLPSSNPQKYLQ MUL_3698|M.ulcerans_Agy99 DPVQQQAIVDYYVN------ELIKPIDQATGHELDLEAVLSASPAQTYLQ MAB_1459c|M.abscessus_ATCC_199 PAWVNFVIVPVYIALAVLIG-------------------AVWGTRRIFKA MLBr_02341|M.leprae_Br4923 TALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVG Mvan_2839|M.vanbaalenii_PYR-1 SWIAAAASVGFGVFQLTFGGPLWWLGAVN--IGCGVVFLAIPRLCPLGEL Mflv_3576|M.gilvum_PYR-GCK GWIAAAVSAAFGAFQLTLGGSLWWLGAVN--VLCALVFLWIPRLCPLGEL TH_2942|M.thermoresistible__bu AWIAAAVSAGFGTLQLVLGGQTRLLGVIN--LAVAVVFTLIPLLYRFGEL Mb1651c|M.bovis_AF2122/97 AWLAVVVTGSFALMQLATGAGGWYIALIN--VFTAVTFAIVPLLHRFGGL Rv1625c|M.tuberculosis_H37Rv AWLAVVVTGSFALMQLATGAGGWYIALIN--VFTAVTFAIVPLLHRFGGL MMAR_2428|M.marinum_M ALLAVLISSSFILVQFLTQAWIWQITLIN--IAATLVFATVPMLHRFGEL MAV_3162|M.avium_104 AWLAVLVCADFILLQVVTGAWTWQIVSLN--VVAALIFAIVPWLHRFGDL MSMEG_3578|M.smegmatis_MC2_155 ALYTAPFTDWDKAIENDDAGDGSGWSAAN--ALFNGFFREIVTRSGFDDA MUL_3698|M.ulcerans_Agy99 AYYTAPFSSSSESMRFNNAGDGSAWSAAN--ARFNDFFRGIVTRFQYRDA MAB_1459c|M.abscessus_ATCC_199 VRWALDERPPTKADQRNAFAVPWRLTVIQSVLWAGGVALFTLLYGLYDPM MLBr_02341|M.leprae_Br4923 EIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAP : . Mvan_2839|M.vanbaalenii_PYR-1 IAPLTFVVFAYTS------------------------------------- Mflv_3576|M.gilvum_PYR-GCK LAPLTFVTFAYMS------------------------------------- TH_2942|M.thermoresistible__bu LAPLSFFLFAYLS------------------------------------- Mb1651c|M.bovis_AF2122/97 VAPLTFIGTAYVA------------------------------------- Rv1625c|M.tuberculosis_H37Rv VAPLTFIGTAYVA------------------------------------- MMAR_2428|M.marinum_M VAPLTFVGAAYVS------------------------------------- MAV_3162|M.avium_104 VAPLTFLGAAYVT------------------------------------- MSMEG_3578|M.smegmatis_MC2_155 LLLDTRGNVVYTAYKGSDLGTNIYTGPYKGGELSEAYREALNSNTVDYVA MUL_3698|M.ulcerans_Agy99 LLLDLQGNVVYSVNEGPDLGTNLFTGPYRETNLRTAYQKALASNEIDFVW MAB_1459c|M.abscessus_ATCC_199 YIPKIFFAVGFSG------------------------------------A MLBr_02341|M.leprae_Br4923 QTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVG-----REWELATLA Mvan_2839|M.vanbaalenii_PYR-1 --------------VGFICYTIGTGSGLQ--FYFLVAASLVVLVLGIERI Mflv_3576|M.gilvum_PYR-GCK --------------VTFFCYTIGTGSGMQ--FYFLVAASLVLLVLGIERV TH_2942|M.thermoresistible__bu --------------VGFMCFSIGTGSGLQ--LYLLVAASLVVLLLGVDRI Mb1651c|M.bovis_AF2122/97 --------------IFAIGWDVGTDAGAQ--FFFLVAAALVVLLVGIEHT Rv1625c|M.tuberculosis_H37Rv --------------IFAIGWDVGTDAGAQ--FFFLVAAALVVLLVGIEHT MMAR_2428|M.marinum_M --------------VFASCWNVGTGSGAQ--MFFLVGACLVVLVLGIEHV MAV_3162|M.avium_104 --------------VFVSCWDVGTASGGQ--YFFLVGACLVLLVMGIEHT MSMEG_3578|M.smegmatis_MC2_155 VTDFGIYQPS-GTPTAWMVSPIGGGGRIEGVLALQFPISVVNQLMTMDGK MUL_3698|M.ulcerans_Agy99 ITDFQRYQPEVDAPTAWLVSPVGVDGKLQGVMALALPPTNLNQIMNANEK MAB_1459c|M.abscessus_ATCC_199 VVCAANYLFTEFAMRPVAARALEAGYRRRRLASGVMVRTVLAWMLGSGVP MLBr_02341|M.leprae_Br4923 AMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESH : : Mvan_2839|M.vanbaalenii_PYR-1 ALAAAIAAAGVIITIVLELTVPDDRGLGP--------------------- Mflv_3576|M.gilvum_PYR-GCK ALAAVIAGVGVVITVVLELTVPEDRGLGP--------------------- TH_2942|M.thermoresistible__bu VLAAGIVAVGVVGIIVLELVVPEDRGLGP--------------------- Mb1651c|M.bovis_AF2122/97 ALAVGLAAVAAGLVIALEFLVPPDTGLQP--------------------- Rv1625c|M.tuberculosis_H37Rv ALAVGLAAVAAGLVIALEFLVPPDTGLQP--------------------- MMAR_2428|M.marinum_M VLASGLAALAAALIITVEFVVPRNTGAQS--------------------- MAV_3162|M.avium_104 VLAAVLAAIGAGLVIAVEFAFPRDTGLQP--------------------- MSMEG_3578|M.smegmatis_MC2_155 WEESGLGETGETYLVGPDGLMRSDSRLFLENPEQFKADVIEAGTPPGVAE MUL_3698|M.ulcerans_Agy99 WEAVGMGRSTETYLAGSDNLMRSDSRLFLESPDEYRREALAGGTREDVVN MAB_1459c|M.abscessus_ATCC_199 AAGIVITGIGALVLHNLTVSQLAVAVIIIAGAIPSFG------------- MLBr_02341|M.leprae_Br4923 ATDVAFDVVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLL : Mvan_2839|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3576|M.gilvum_PYR-GCK -------------------------------------------------- TH_2942|M.thermoresistible__bu -------------------------------------------------- Mb1651c|M.bovis_AF2122/97 -------------------------------------------------- Rv1625c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2428|M.marinum_M -------------------------------------------------- MAV_3162|M.avium_104 -------------------------------------------------- MSMEG_3578|M.smegmatis_MC2_155 QSILHGGTTLVQPVSDEASKLAGQGQSGSIIERDYLGQETLQAYAPLDLT MUL_3698|M.ulcerans_Agy99 KAMWLGTTVLVQPVPSAGLRAALRGQSGITKDTDYLGNRELEAYAPLDVP MAB_1459c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_02341|M.leprae_Br4923 G-------------------------IADPAVELPRLDPDARRRRLTALI Mvan_2839|M.vanbaalenii_PYR-1 ------------------------SWTLTAGFISAVVSSVVIIVATIWYT Mflv_3576|M.gilvum_PYR-GCK ------------------------SWTLTAGFISAVTSSAVMIVATIWYT TH_2942|M.thermoresistible__bu ------------------------AWMLTAGFVTSAVSSALIIFATLWYA Mb1651c|M.bovis_AF2122/97 ------------------------PWAMSVSFVLTTVSACGVAVATVWFA Rv1625c|M.tuberculosis_H37Rv ------------------------PWAMSVSFVLTTVSACGVAVATVWFA MMAR_2428|M.marinum_M ------------------------AWLQSLGFIITTVSACLLVFVTVWFA MAV_3162|M.avium_104 ------------------------AWAQSMSFVVTIVSACIMVFVAVWFA MSMEG_3578|M.smegmatis_MC2_155 G--LDWSVVAKIDTAEAFAPVTKFTRTLVLSTVAMIFAVCIAAILLARVF MUL_3698|M.ulcerans_Agy99 NSDLRWAILATRDDWDAYERLSSFGRTVVLAVAGITLFICVVSMVLAKLL MAB_1459c|M.abscessus_ATCC_199 -----------------LILIWIASWLMATPVKEVQTAIKRVAQNDLDID MLBr_02341|M.leprae_Br4923 NVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPE Mvan_2839|M.vanbaalenii_PYR-1 LREIDRAEA----------------------------------------- Mflv_3576|M.gilvum_PYR-GCK LREIERAES----------------------------------------- TH_2942|M.thermoresistible__bu LREIARTEA----------------------------------------- Mb1651c|M.bovis_AF2122/97 LRDTARAEA----------------------------------------- Rv1625c|M.tuberculosis_H37Rv LRDTARAEA----------------------------------------- MMAR_2428|M.marinum_M LRDTARAEA----------------------------------------- MAV_3162|M.avium_104 LRDTQRAEA----------------------------------------- MSMEG_3578|M.smegmatis_MC2_155 VRPIRRLEAGAQQISAGDYGVALPVVSRDEFGDLTVAFNEMSRNLRIKED MUL_3698|M.ulcerans_Agy99 VRPIRRLEAGTEKIRSGDYEVTVPVKSRDELGDLTAAFNEMSSNLKVKDQ MAB_1459c|M.abscessus_ATCC_199 LVVYDGTELGELQAGFN------------------------------TMV MLBr_02341|M.leprae_Br4923 YHGALRHVVGAQIIAVAPLSDVETSTLVAELLG--------LDQSVTQIG Mvan_2839|M.vanbaalenii_PYR-1 AMAAEYERSEELLANILPATIADR--------------------LKEPTR Mflv_3576|M.gilvum_PYR-GCK AMENEYERSERLLANILPATIAER--------------------LKEPTR TH_2942|M.thermoresistible__bu AMEAEYQRSESLLLNILPASVARR--------------------LKDPAR Mb1651c|M.bovis_AF2122/97 VMEAEHDRSEALLANMLPASIAER--------------------LKEPER Rv1625c|M.tuberculosis_H37Rv VMEAEHDRSEALLANMLPASIAER--------------------LKEPER MMAR_2428|M.marinum_M VMEAQYDRSEALLANMLPVSVADR--------------------LKEPER MAV_3162|M.avium_104 VMESEYQRSEALLANMLPGSIAER--------------------LKHSDG MSMEG_3578|M.smegmatis_MC2_155 LLDEQRKENDRLLLSLMPEPVVQR--------------------YRE-GE MUL_3698|M.ulcerans_Agy99 LLTEQRSQNEQLLLALMPEPVVQR--------------------YRA-DG MAB_1459c|M.abscessus_ATCC_199 EGLRERERVRDLFGKHVGREVAAA--------------------AEQ-QQ MLBr_02341|M.leprae_Br4923 ELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQ : :: : :. Mvan_2839|M.vanbaalenii_PYR-1 TVIADKYDDASILFADIAGYTKRASETPPSELVRFLDRLYTDLDALVDRH Mflv_3576|M.gilvum_PYR-GCK TVIADKYDDASILFADIAGYTKRASDTAPAELVRFLDLLYTDLDALVDRH TH_2942|M.thermoresistible__bu TVIADKYDDASVLFADIAGYTRWAGATTPSELVLFLDRLYTELDALVDRH Mb1651c|M.bovis_AF2122/97 NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQH Rv1625c|M.tuberculosis_H37Rv NIIADKYDEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDELVDQH MMAR_2428|M.marinum_M NIIADKYEEASVLFADIVGFTERASSTAPADLVRFLDRLYSAFDALVDKY MAV_3162|M.avium_104 DIIADKYDDASVLFADIVGFTERASGTAPADLVRFLNRLYIAFDELVDKH MSMEG_3578|M.smegmatis_MC2_155 ETIAQDHQNVTVLFADLMGLDRLSASMSSDEHLSIVNKLVRQFDAAAESL MUL_3698|M.ulcerans_Agy99 EVIAEEHQDVTVIFAELIGLEEISDGLSGDELVGIVDELFRQFDSAAQSL MAB_1459c|M.abscessus_ATCC_199 PELGGEERHIAVLFADIVGSTRLAATRPAVEVVALLNRFFTVVVEEIDRY MLBr_02341|M.leprae_Br4923 ATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG-IDLSVDELIDAN :. : :: : : :. : . : Mvan_2839|M.vanbaalenii_PYR-1 GLEKVKTSGDSYMVVSGVPNPRADHLEALALLALDMADAVADLKDPQGHD Mflv_3576|M.gilvum_PYR-GCK GLEKVKTSGDSYMVVSGVPTPRPDHLEALATLALDMSEAVADLKDPRGRD TH_2942|M.thermoresistible__bu GLEKVKTSGDSYMVVSGVPQPRPDHLEALADFALDMAAAVGRLRDPQGRT Mb1651c|M.bovis_AF2122/97 GLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNP Rv1625c|M.tuberculosis_H37Rv GLEKIKVSGDSYMVVSGVPRPRPDHTQALADFALDMTNVAAQLKDPRGNP MMAR_2428|M.marinum_M GLEKIKVSGDSYMVVSGVPRPRPDHVQALADFALDMVDVAAGMKDPHNRS MAV_3162|M.avium_104 GLEKIKVSGDSYMVVSGVPRVRPDHATALADFALDMVKVAAALKDPYGRP MSMEG_3578|M.smegmatis_MC2_155 GVERVRTLHNGYLASCGLTVPRLDNVRRTVDFAFEMQRIVDRFRGETGYD MUL_3698|M.ulcerans_Agy99 GVEPIRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVNRFANQSQHP MAB_1459c|M.abscessus_ATCC_199 EGMVNKFEGDATLAVFGAPVRQ----DRPESQALAAARAIARRLRTEVPE MLBr_02341|M.leprae_Br4923 LVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPH : . Mvan_2839|M.vanbaalenii_PYR-1 --VPLRIGMASGPVVAGVVGAKK-FFYDVWGDAVNVASRMETTDVEGRIQ Mflv_3576|M.gilvum_PYR-GCK --VPLRIGMAMGPVVAGVVGAKK-FFYDVWGDAVNVASRMETTDEEGRIQ TH_2942|M.thermoresistible__bu --VPLRIGLAAGPVVAGVVGARK-FFYDVWGDAVNVGSRMESTDVVGRIQ Mb1651c|M.bovis_AF2122/97 --VPLRVGLATGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGQIQ Rv1625c|M.tuberculosis_H37Rv --VPLRVGLATGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGQIQ MMAR_2428|M.marinum_M --VPLRVGLATGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGKIQ MAV_3162|M.avium_104 --VPLRVGMACGPVVAGVVGSRR-FFYDVWGDAVNVASRMESTDSVGRIQ MSMEG_3578|M.smegmatis_MC2_155 --LRLRAGIDTGTVSSGLVGRSS-LAYDMWGAAVDLAYQVQRGMPQPGVY MUL_3698|M.ulcerans_Agy99 --LRVRVGVTTGRVVSGRVGRSN-LAYDMWGGAVQMAYRMLGHLSDPGIY MAB_1459c|M.abscessus_ATCC_199 --CQAGIGVASGQAVAGNIGAHDRFEYTVIGDPVNEAARLCELSKT---- MLBr_02341|M.leprae_Br4923 SVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK : :* : . ..: : Mvan_2839|M.vanbaalenii_PYR-1 VPDNVYERLRDRFVLEERGVVDVKGKGPMHTWYLVAHR------------ Mflv_3576|M.gilvum_PYR-GCK VPDNVYQRLRHAFVLEERGLIDVKGKGPMHTWYLVGHR------------ TH_2942|M.thermoresistible__bu VAQDVRDRLRDSFVFEERGAIEVKGKGVMHTWYLLGRRSDRQGSDRQGSG Mb1651c|M.bovis_AF2122/97 VPDEVYERLKDDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGE----- Rv1625c|M.tuberculosis_H37Rv VPDEVYERLKDDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGE----- MMAR_2428|M.marinum_M VPDEVYERLNKDFVLQERGHINVKGKGVMRTWYLIGRKPIDEPTA----- MAV_3162|M.avium_104 VPETMYERLASEFVLQERGRIEVKGKGVMRTWYLIGRKPAEAPTD----- MSMEG_3578|M.smegmatis_MC2_155 VTDQVHDAVRDIRQFTAVGSVTVDGTE-RPIWRLSERQS----------- MUL_3698|M.ulcerans_Agy99 VSARVHDAMREIWTFTPAGAISVRGSQ-QQIWQVSERR------------ MAB_1459c|M.abscessus_ATCC_199 VPGHLVASLDTVLRAHHREALHWRSGDTVTLRGRTEPTELAVPV------ MLBr_02341|M.leprae_Br4923 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCN---- :. : . Mvan_2839|M.vanbaalenii_PYR-1 --------------AEAVTPSGSPT------ Mflv_3576|M.gilvum_PYR-GCK --------------ARAVTPSSSPP------ TH_2942|M.thermoresistible__bu RQGSGRQGSGRQGGTEASTAARTHG------ Mb1651c|M.bovis_AF2122/97 --------------VRGAEPRTAGV------ Rv1625c|M.tuberculosis_H37Rv --------------VRGAEPRTAGV------ MMAR_2428|M.marinum_M --------------VPADEPNAARV------ MAV_3162|M.avium_104 --------------LVAEQPHTAHV------ MSMEG_3578|M.smegmatis_MC2_155 ------------------------------- MUL_3698|M.ulcerans_Agy99 ------------------------------- MAB_1459c|M.abscessus_ATCC_199 ------------------------------- MLBr_02341|M.leprae_Br4923 -----ATGDKAPLAVATVGPAIDHVYQDRLH