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MSLLITSPATVAAAATHLAGIGSALSTANAAAAAPTTALSVAGADEVSVLIAALFEAYAQEYQALSAQAL AFHDQFVQALNMGAVCYAAAETANATPLQALQTVQQNVLTVVNAPTQALLGRPIIGNGANGLPNTGQDGG PGGLLFGNGGNGGSGGVDQAGGNGGAAGLIGNGGSGGVGGPGIAGSAGGAGGAGGLLFGNGGPGGAGGIG TTGDGGPGGAGGNAIGLFGSGGTGGMGGVGGMGGVGNGGNAGNGGTAGLFGHGGAGGAGGIGSADGGLGG GGGNGRFMGNGGVGGAGGYGASGDGGNAGNGGLGGVFGDGGAGGTGGLGDVNGGLAGIGGNAGFVRNGGA GGNGQLGSGAVSSAGGMGGNGGLVFGNGGPGGLGGPGTSAGNGGMGGNAVGLFGQGGAGGAGGSGFGAGI PGGRGGDGGSGGLIGDGGTGGGAGAGDAAASAGGNGGNARLIGNGGDGGPGMFGGPGGAGGSGGTIFGFA GTPGPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0109 | PE_PGRS1 | - | 100% (496) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1840c | PE_PGRS34 | e-148 | 54.49% (534) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1768 | PE_PGRS31 | e-147 | 51.03% (631) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0113 | PE_PGRS1 | 0.0 | 99.80% (496) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-87 | 47.63% (401) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 7e-13 | 38.46% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-45 | 38.89% (360) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0299 | - | 0.0 | 59.57% (559) | PE-PGRS family protein, PE_PGRS1 |
| M. avium 104 | MAV_4827 | - | 1e-23 | 45.18% (166) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-68 | 37.23% (556) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-39 | 41.69% (295) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 1e-145 | 49.84% (614) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-87 | 49.87% (385) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------MNIVLGV
Rv0109|M.tuberculosis_H37Rv -----------MSLLITSPATVAAAATHLAGIGSALSTANAAAAAPTTAL
Mb0113|M.bovis_AF2122/97 -----------MSLLITSPATVAAAATHLAGIGSALSTANAAAAAPTTAL
MMAR_0299|M.marinum_M -----------MSYVFATPELVAAAATDLAGVQSVLSAANSAAAGPTMAV
MUL_1145|M.ulcerans_Agy99 -----------MSYVVASPEYVAAAASDLAGIGSALSTANAAAAAPTIEV
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 ----------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEI
MAB_4284c|M.abscessus_ATCC_199 ---MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPV
MAV_4827|M.avium_104 SMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILG
Rv0109|M.tuberculosis_H37Rv SVAGADEVSVLIAALFEAYAQEYQALSAQALAFHDQFVQALNMGAVCYAA
Mb0113|M.bovis_AF2122/97 SVAGADEVSVLIAALFEAYAQEYQALSAQALAFHDQFVQALNMGAVCYAA
MMAR_0299|M.marinum_M MAAGADEVSALIAGLFDAHAQAYQALSAQALVFHDQFVQMLNAGASSYAA
MUL_1145|M.ulcerans_Agy99 LAAGADEVSAAIAAFFGAHAQAYQALSEQASAFHLQFVQAMTAGAGAYAG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923 APPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAG
MAB_4284c|M.abscessus_ATCC_199 VAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSP
MAV_4827|M.avium_104 TREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAA
. . . :
Rv0109|M.tuberculosis_H37Rv AETANATPLQALQTVQQNVLTVVNAPTQALLGRPIIG-------------
Mb0113|M.bovis_AF2122/97 AETANATPLQALQTVQQNVLTVVNAPTQALLGRPIIG-------------
MMAR_0299|M.marinum_M AEAANASPLQVVQNLGQNVLAAVNAPTQAVLGRPLIG-------------
MUL_1145|M.ulcerans_Agy99 AEAVNASPLQAA-------LDVLNAPAQALFGRPLIG-------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MLBr_01183|M.leprae_Br4923 TETANHDSL-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRG------------
MAV_4827|M.avium_104 ALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------P
MAV_4827|M.avium_104 --------------------------------------------------
Rv0109|M.tuberculosis_H37Rv --------NGANGLPNTGQDGGPGGLLFG-NGGNGGSGGVDQAGGNGGAA
Mb0113|M.bovis_AF2122/97 --------NGANGLPNTGQDGGPGGLLFG-NGGNGGSGGVDQAGGNGGAA
MMAR_0299|M.marinum_M --------DGANGSPNTGADGGAGGLLYG-NGGNGGSGGLAQAGGNGGAA
MUL_1145|M.ulcerans_Agy99 --------DGAGGAP--GQSGGDGGLLYG-NGGNGGNGGVGQAGGAGGAA
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDS
MAV_4827|M.avium_104 ----DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVA
Rv0109|M.tuberculosis_H37Rv GLIGNGGSGGVG--------------------GPGIAGSAGGAGGAGGLL
Mb0113|M.bovis_AF2122/97 GLIGNGGSGGVG--------------------GPGIAGSAGGAGGAGGLL
MMAR_0299|M.marinum_M GLIGNGGSGGAG--------------------GADFAGTSGGMGGTGGWL
MUL_1145|M.ulcerans_Agy99 GLIGNGGSGGIG--------------------GPGTTGLAGGAGGSGGWL
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGGAGGWG--------------------GSGVDG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NIINADHGSNVG----------------VDQSQTRVGGDYTNVSGHGSAD
MAV_4827|M.avium_104 PLKQVLQTTTFLDVS------------VAEEPETALARGAALAAANAPLF
Rv0109|M.tuberculosis_H37Rv FG---------NGGPGG---------------------------------
Mb0113|M.bovis_AF2122/97 FG---------NGGPGG---------------------------------
MMAR_0299|M.marinum_M WG---------NGGAGG---------------------------------
MUL_1145|M.ulcerans_Agy99 FG---------NGGTGG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu -----------VDVVGG---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IDKSVTVVDDHSQRNTTNIN------------------------------
MAV_4827|M.avium_104 ASSTAALAYAQDPGTGAVDQYS--------------------------LP
Rv0109|M.tuberculosis_H37Rv -AGGIGTTGDGGPGGAGGNAIGLFG---------------------SGGT
Mb0113|M.bovis_AF2122/97 -AGGIGTTGDGGPGGAGGNAIGLFG---------------------SGGT
MMAR_0299|M.marinum_M -GGGVGTTTTGGTGGAGGNAMGLFG---------------------NGGI
MUL_1145|M.ulcerans_Agy99 -RGGIGTTGIGGIGGTGGDAVGLFG---------------------HGGT
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DSFNTDRSTNIGSGNTTNTEIGSHNQAN---------------IGTSTSA
MAV_4827|M.avium_104 DYLYVPVDPEPGDDELAYSAVG------------------------EEDA
Rv0109|M.tuberculosis_H37Rv GGMGGVG-------------------------------------------
Mb0113|M.bovis_AF2122/97 GGMGGVG-------------------------------------------
MMAR_0299|M.marinum_M GGAGGVGQNTTGTGGNGGAGGNAAL-------------------------
MUL_1145|M.ulcerans_Agy99 GGTGGNGPDIFIAGGAGGSGGTGG--------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSAAVGGNAGLAGN-----------------------------------
MAV_4827|M.avium_104 ESPTVVIEKLFLPEDSEPRRR-----------------------------
Rv0109|M.tuberculosis_H37Rv ------------GMGGVG-----NGGNAGNGGTAG--------------L
Mb0113|M.bovis_AF2122/97 ------------GMGGVG-----NGGNAGNGGTAG--------------L
MMAR_0299|M.marinum_M --------LGFAGAGGVGGLGGATGGDGGQGGNAA--------------L
MUL_1145|M.ulcerans_Agy99 ---------LLFGNGGAGGGAPWGGADGGAGGDAR--------------L
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAGLAGNAGLAGN---------------
MAV_4827|M.avium_104 --------PVLLVGSGLAVVGISAVLALEIALAIG---------------
Rv0109|M.tuberculosis_H37Rv FGHGGAGGAGGIGS-----ADGGLGGGGGNGR----FMGNGGVGGAG---
Mb0113|M.bovis_AF2122/97 FGHGGAGGAGGIGS-----ADGGLGGGGGNGR----FMGNGGVGGAG---
MMAR_0299|M.marinum_M FGNGGDGGAGGAGAN----LDGGNGGLGGNAG----LFGDGGHGGAGGVS
MUL_1145|M.ulcerans_Agy99 IGNGGGGGYEGSLGV----LSGGTAGPGGDGGNAVGLIGNGGAGGAGAAG
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104 IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKP
Rv0109|M.tuberculosis_H37Rv --------------------GYGASG----------------DGGNAGNG
Mb0113|M.bovis_AF2122/97 --------------------GYGASG----------------DGGNAGNG
MMAR_0299|M.marinum_M FDPAGGDGGNGGQGGNATLFGYGGHGGAGGSS-------LNLAGGDGGDG
MUL_1145|M.ulcerans_Agy99 LSGVTG-GIGGNGGNGAQLFGNGGAGGAGGQS-------QLASGGTGGSG
Mflv_5091|M.gilvum_PYR-GCK GTGGTG-GAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTG-GDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GDGALG-GNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
TH_3810|M.thermoresistible__bu GRGGFL-GIGGSG-------GWGGHGGNGGD-----------TDADGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG------NAGLAGNAGLA
MAV_4827|M.avium_104 LSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRI
Rv0109|M.tuberculosis_H37Rv GLG------------GVFGDGGAGG-------------------------
Mb0113|M.bovis_AF2122/97 GLG------------GVFGDGGAGG-------------------------
MMAR_0299|M.marinum_M GQG------------GFFGGGGAGG-------------------------
MUL_1145|M.ulcerans_Agy99 GMA------------ALFGNGGAGGAAGVSLSGAPGTGGNGGS-------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
TH_3810|M.thermoresistible__bu GDG---------------GNGGSAG-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAAVAGNAAVAGNAAVAGNAAVGG-------------------------
MAV_4827|M.avium_104 PVP-----------DPVSPPQLLAP-------------------------
Rv0109|M.tuberculosis_H37Rv --------TGGLGDVNG--GLAGIGGNAG---------------------
Mb0113|M.bovis_AF2122/97 --------TGGLGDVNG--GLAGIGGNAG---------------------
MMAR_0299|M.marinum_M --------DGGAGYVLANAGAAGNGGDAG---------------------
MUL_1145|M.ulcerans_Agy99 AQFMGDGDSGGLGDSGGSAGAAGAGGLIGNPLDVVNAPTEALLGRPLIGD
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG------------------------
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAY---------------N
TH_3810|M.thermoresistible__bu --------RGGTGGLRGVFGINGGNG------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----VLNTGVSGAIGGSSHVGGAINESLG--------------------
MAV_4827|M.avium_104 ------PRLSVPQPVQPPVRVPQPPSPPQ---------------------
Rv0109|M.tuberculosis_H37Rv ---------------FVRNGGAGGNGQ----------------------L
Mb0113|M.bovis_AF2122/97 ---------------FVGNGGAGGNGQ----------------------L
MMAR_0299|M.marinum_M ---------------FFGNGGAGGSGQ----------------------F
MUL_1145|M.ulcerans_Agy99 GADGAPGESGQDGGLLYGNGGNGGNGLSGQAGGAGGAAGLIGNGGNGGIG
Mflv_5091|M.gilvum_PYR-GCK --------------GQGGTGGTGGQGGT---------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------------GTGGTGGTGGQGGT---------------------G
MSMEG_0868|M.smegmatis_MC2_155 VVQANPQASGTATDGHGGSGINGGHGGN---------------------G
TH_3810|M.thermoresistible__bu ---------------RAGLGGRGXXXXG---------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------GSGSVGGSTAVGGG-------------------AHT
MAV_4827|M.avium_104 ---------------VGGTVPQSPPQHQTP-------------------P
Rv0109|M.tuberculosis_H37Rv GSGAVSSAG----------GMGGNGGLVFGNGGPGGLGGPGT----SAGN
Mb0113|M.bovis_AF2122/97 GSGAVSSAG----------GMGGNGGLVFGNGGPGGLGGPGT----SAGN
MMAR_0299|M.marinum_M GVG-ASSAG----------GIGGNGGRVIGDGGDGGVGGWGV----LAAA
MUL_1145|M.ulcerans_Agy99 GPGTTGMSG----------GAGGAGGWLIGNGGHGGIGGLGIGIGDSGGA
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGG----QGGL
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGG----QGGQ
MSMEG_0868|M.smegmatis_MC2_155 GQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNT----TANA
TH_3810|M.thermoresistible__bu GVGAAVRSG---------------NGVFSGGGGTPSAGFGVP----TTIQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGGGVSTG-------VGVGSHVGGGISESLGGSGSVGGSTAVG--GGAH
MAV_4827|M.avium_104 GEGTPPKPD-------GPGNYGGGHVPTPGAGGSGGSGGGHVPTPGAGGS
Rv0109|M.tuberculosis_H37Rv GGMGGNAVGLFGQGGAGGAG------------------------------
Mb0113|M.bovis_AF2122/97 GGMGGNAVGLFGQGGAGGAG------------------------------
MMAR_0299|M.marinum_M GGKGGDAIGLFGQGGAGGTG------------------------------
MUL_1145|M.ulcerans_Agy99 GGAGGAAIGLFGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGG
Mflv_5091|M.gilvum_PYR-GCK GGPGGSTGGAGGAGG--QAGTAGKGGLFG-----------GSGSAGKAGA
Mvan_1264|M.vanbaalenii_PYR-1 GGPGGSTGGAGGAGG--QAGVAGKGGLFG-----------GSGSAGTAGV
MSMEG_0868|M.smegmatis_MC2_155 ANPGSATGTATGGDGGKATGTASQGGNGGP-------SWVQSGYGSTLGG
TH_3810|M.thermoresistible__bu FPAGSCTSRAVSREG-------------------------------IMPS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVGGGVSTGVGVGSHVGGGISESLGGSGS-----------VGGSTAVGG
MAV_4827|M.avium_104 GGSGGGHVPTPGTGGPGGTG------------------------------
Rv0109|M.tuberculosis_H37Rv ----GSGFGAG------------------------IPGGRG---------
Mb0113|M.bovis_AF2122/97 ----GSGFGAG------------------------IPGGRG---------
MMAR_0299|M.marinum_M ----GAAVGAG------------------------NHGGNG---------
MUL_1145|M.ulcerans_Agy99 TSWGGAAAGAGGDAGLIDNGGDGDSAGVLRQNGIGGHGGAGGSLFGDGGD
Mflv_5091|M.gilvum_PYR-GCK TGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKA------
Mvan_1264|M.vanbaalenii_PYR-1 TGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQ------
MSMEG_0868|M.smegmatis_MC2_155 NATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATG------
TH_3810|M.thermoresistible__bu SRAASARAG---------------------------AACASSTS------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVNTGVGVGSHVGGG---ISESLGGSGSVGGSTAVG------
MAV_4827|M.avium_104 ----GSGGGHVP------------------------TPGAGTPG------
Rv0109|M.tuberculosis_H37Rv ----------GDGGSGGLIGDGGTG-------------------------
Mb0113|M.bovis_AF2122/97 ----------GDGGSGGLIGDGGTG-------------------------
MMAR_0299|M.marinum_M ----------GDGGTGALIGNGGDG-------------------------
MUL_1145|M.ulcerans_Agy99 GGSAGFQSTAGDGGNAGLVGNGGNGGWAIYNSFAGDDGSGGTAIGNGGDG
Mflv_5091|M.gilvum_PYR-GCK ----------GATGAAGAAGAAGSAG-----------TTGAQGSAG----
Mvan_1264|M.vanbaalenii_PYR-1 ----------GSAGSAGSAGVAGSAG-----------TTGAQGSAG----
MSMEG_0868|M.smegmatis_MC2_155 ----------GDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISG----
TH_3810|M.thermoresistible__bu ----------RSRRSFCCSRA-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------GGAHTSAINDALGGSG------------------------
MAV_4827|M.avium_104 ---------GSGGGHLPFPGAGSTPG------------------------
Rv0109|M.tuberculosis_H37Rv --------------------------------------------------
Mb0113|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GANIVSSGFILGAGGGGNGGNAVGLIGNGGAGGTGADGFSTALGSDGGNG
Mflv_5091|M.gilvum_PYR-GCK --------TNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDG
Mvan_1264|M.vanbaalenii_PYR-1 --------TNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAG
MSMEG_0868|M.smegmatis_MC2_155 --------HGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0109|M.tuberculosis_H37Rv ---------------------------------------GGAGAGDAAAS
Mb0113|M.bovis_AF2122/97 ---------------------------------------GGAGAGDAAAS
MMAR_0299|M.marinum_M ---------------------------------------GAAGTSIGQSA
MUL_1145|M.ulcerans_Agy99 GTGAWLLGNGGAGGSGGSTAGVHPAGDGGNSGMSALIGNGGAGGSAGVSP
Mflv_5091|M.gilvum_PYR-GCK DAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-
Mvan_1264|M.vanbaalenii_PYR-1 DPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-
MSMEG_0868|M.smegmatis_MC2_155 DGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------SVGGSTAVGGGAHTSAINES
MAV_4827|M.avium_104 -------------------------------------GSGGGHLPTPGAG
Rv0109|M.tuberculosis_H37Rv A------GGNGGNARLIGNGGDGGPGMFGGPGGAGGSGGTIFGFAGTPGP
Mb0113|M.bovis_AF2122/97 A------GGNGGNARLIGNGGDGGPGMFGGPGGAGGSGGTIFGFAGTPGP
MMAR_0299|M.marinum_M S------GGNGGNARFLGNGGDGGPGIFGGTGGTGGQGGTLAGVPGAAGP
MUL_1145|M.ulcerans_Agy99 TGVFPSNGGSGGNAQLIGDGGDGGRGDSGGTGGAGGTGGSLAGHDGSDGD
Mflv_5091|M.gilvum_PYR-GCK -------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGD
Mvan_1264|M.vanbaalenii_PYR-1 -------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGD
MSMEG_0868|M.smegmatis_MC2_155 GPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 MNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLP
MAV_4827|M.avium_104 TPGGGLGGFGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGL
Rv0109|M.tuberculosis_H37Rv S----
Mb0113|M.bovis_AF2122/97 S----
MMAR_0299|M.marinum_M S----
MUL_1145|M.ulcerans_Agy99 -----
Mflv_5091|M.gilvum_PYR-GCK SDD--
Mvan_1264|M.vanbaalenii_PYR-1 SD---
MSMEG_0868|M.smegmatis_MC2_155 NNP--
TH_3810|M.thermoresistible__bu -----
MLBr_01183|M.leprae_Br4923 -----
MAB_4284c|M.abscessus_ATCC_199 GAEHH
MAV_4827|M.avium_104 GGGHK