For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TARSDQAVRHWFITGASGGLGHHLAECALRQGDRVTATVRRATALADLCDAYGDRLTVEVLDLAEPHDIA PVIERTLLAGPVDIVVNNAGYVVVGAAEEMTVEQIRDQIDVLLMAPMLITRAFLKPMREQGGGRIIQISS MGGQVAVPTHSAYHAAKWGLEGFTESVSREVAEFGIRLTLVEPGGTRTGFASAMQYTVESEPYRQTAVGQ TRRVLENADDTAFAGDPAKIAAVIYDSTRNPDPPLRLTLGDDSYHAIRVGLTERLAALDESRELSASVAF TD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3451 | - | - | 100% (283) | short-chain dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_1114 | - | 2e-41 | 39.54% (263) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3302 | - | 5e-38 | 35.93% (270) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3083c | - | 1e-20 | 31.28% (195) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0295 | - | 4e-43 | 39.71% (272) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3057c | - | 1e-20 | 31.28% (195) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01740 | - | 2e-18 | 30.53% (190) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1305 | - | 1e-23 | 34.34% (198) | short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1614 | - | 5e-34 | 34.66% (277) | short chain dehydrogenase |
| M. avium 104 | MAV_4982 | - | 7e-42 | 36.76% (272) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3670 | - | 9e-43 | 39.08% (261) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3423 | - | 5e-34 | 34.66% (277) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0982 | - | 4e-46 | 42.02% (257) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3670|M.thermoresistible__bu MGSNVWG------SKVWFITGASRGFGREWAIAALDRGDRVAATARDVST
Mvan_0982|M.vanbaalenii_PYR-1 MPGHPTGIDPGMTEKVWFITGASRGFGREWAIAALDRGDKVAATARDLST
Mflv_0295|M.gilvum_PYR-GCK ------------MSKVLLISGASRGLGRAITESALAAGHLVVAGVRATSS
MAV_4982|M.avium_104 ------------MPKTWFITGSSRGLGRALTTAVLDHGDHVVATARRPAQ
MMAR_1614|M.marinum_M ------------MS-TWLITGCSTGLGRALAEAVIDAGHHTVATARSVGG
MUL_3423|M.ulcerans_Agy99 ------------MS-TWLITGCSTGLGRALAEAVIDAGHHTVATARSVGG
MSMEG_3451|M.smegmatis_MC2_155 -----MTARSDQAVRHWFITGASGGLGHHLAECALRQGDRVTATVRRATA
Mb3083c|M.bovis_AF2122/97 --MLQRGAGQYFAGKRCFVTGAASGIGRATALRLAAQGAELYLTDRDRDG
Rv3057c|M.tuberculosis_H37Rv --MLQRGAGQYFAGKRCFVTGAASGIGRATALRLAAQGAELYLTDRDRDG
MLBr_01740|M.leprae_Br4923 --MVKT--AQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCDG
MAB_1305|M.abscessus_ATCC_1997 ----------MSEHWTVLVTGASSGIGASAARIFAERGHRVFGTSRNPDT
:::*.: *:* : * *
TH_3670|M.thermoresistible__bu LDDLRDRF----GDAVLAMTLDVTDRAADFAAVQRAHDHFGRLDIVVNNA
Mvan_0982|M.vanbaalenii_PYR-1 LDDLTAKY----GDALLPLTLDVTDRDADFAAVTQAHDHFGRLDIVVNNA
Mflv_0295|M.gilvum_PYR-GCK LSDLATRE----PDRLAVVELDVTDDRHARAAVATAVERFGRLDVLVNNA
MAV_4982|M.avium_104 LDELVDRY----GPRIRACELDVTDRAAARRAIAAAVTAFGRIDVVVNNA
MMAR_1614|M.marinum_M VADLVQRS----PERVLPLALDITEPDQITAAVQAAQQRFGGIDVLVNNA
MUL_3423|M.ulcerans_Agy99 VADLAQRS----PERVLPLALDITEPDQITAAMQAAQQRFGGIDVLVNNA
MSMEG_3451|M.smegmatis_MC2_155 LADLCDAY----GDRLTVEVLDLAEP-HDIAPVIERTLLAGPVDIVVNNA
Mb3083c|M.bovis_AF2122/97 LAQTVCDARALGAQVPEHRVLDVSDYQDVAAFAADIHARHPSMDVVLNIA
Rv3057c|M.tuberculosis_H37Rv LAQTVCDARALGAQVPEHRVLDVSDYQDVAAFAADIHARHPSMDVVLNIA
MLBr_01740|M.leprae_Br4923 LAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARHPSMDIVMNIA
MAB_1305|M.abscessus_ATCC_1997 ITDRVPGV--------QYLRLDQTDK----ASIAECVAQAGEVDILVNNA
: : ** :: :*:::* *
TH_3670|M.thermoresistible__bu GYGHFGFVEELTETEVRDQMETNFFGALWVTQAALPYLRRQ-RSGHIIQV
Mvan_0982|M.vanbaalenii_PYR-1 GYGQFGFVEELSEQEARAQIDTNVFGALWITQAALPYLRAQ-RSGHLIQV
Mflv_0295|M.gilvum_PYR-GCK GYANMSAIEDVDVDDFRAQIETNFFGVVNLTRAALPAMRRQ-RDGHIVQI
MAV_4982|M.avium_104 GYANSAPVEEVSDDDFRAQVETNFFGVVNVTKAALPVLHRQ-RAGHIVQI
MMAR_1614|M.marinum_M GYGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRAR-RSGAIVNI
MUL_3423|M.ulcerans_Agy99 GYGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRAR-RSGAIVNI
MSMEG_3451|M.smegmatis_MC2_155 GYVVVGAAEEMTVEQIRDQIDVLLMAPMLITRAFLKPMREQ-GGGRIIQI
Mb3083c|M.bovis_AF2122/97 GVSAWGTVDQLTHDQWSRMVAINLMGPIHVIETLVPPMVAAGRGGHLVNV
Rv3057c|M.tuberculosis_H37Rv GVSAWGTVDQLTHDQWSRMVAINLMGPIHVIETLVPPMVAAGRGGHLVNV
MLBr_01740|M.leprae_Br4923 GVSVWGTVDRLTHDQWSNVVAINLMGPIHIIETFVPAILAAGRGGHLVNV
MAB_1305|M.abscessus_ATCC_1997 GESQIGALEDVSMDDFEKLYMTNVFGPVALTKAVLPGMRER-RRGAVVMV
* . : : .:. : : .: : : * :: :
TH_3670|M.thermoresistible__bu SSIGG-VSAFADLGAYHASKWALEGLSQSLSLEVAPFGIHVTLIEPGGYA
Mvan_0982|M.vanbaalenii_PYR-1 SSIGG-IVAFPNLGIYHASKWALEGFSQALAQEVAEFGIHVTLIEPGGYS
Mflv_0295|M.gilvum_PYR-GCK SSVGGRLVR-PGLAAYQSAKWAVTGFSGVLAVEVAPLGIKVTVLEPGGMR
MAV_4982|M.avium_104 SSVGGRVGGSPGIAAYQASKFAVAGFSEALAAEVAPLGIKVTIAEPGALR
MMAR_1614|M.marinum_M SSIAVALTP-VGSGYYAAAKAAMEGMSGALHGELAPLGISVTVVEPGAFR
MUL_3423|M.ulcerans_Agy99 SSIAVALTP-VGSGYYAAAKAAMEGMSGALHGELAPLGISVTVVEPGAFR
MSMEG_3451|M.smegmatis_MC2_155 SSMGG-QVAVPTHSAYHAAKWGLEGFTESVSREVAEFGIRLTLVEPGGTR
Mb3083c|M.bovis_AF2122/97 SSAAG-LVGLPWHAAYSASKYGLRGLSEVLRFDLARHGIGVSVVVPGAVK
Rv3057c|M.tuberculosis_H37Rv SSAAG-LVGLPWHAAYSASKYGLRGLSEVLRFDLARHGIGVSVVVPGAVK
MLBr_01740|M.leprae_Br4923 SSAAG-LVALPWHAAYSASKYGLRGLSEVLRFDLARYRIGVSVVVPGAVR
MAB_1305|M.abscessus_ATCC_1997 GSMAG-TLHVPFRSTYSSAKSALHTVADCLRYEVAPFGITVSTVEPGVIA
.* . . * ::* .: .: : ::* * :: **
TH_3670|M.thermoresistible__bu TDWGGSSARRSA-TMPEYAESRAEADRVRSQR--VARPGDPKASAAALLK
Mvan_0982|M.vanbaalenii_PYR-1 TDWAGASAKRAT-ALPAYAEAHAATERTRQAR--TARPGDPQASARALLT
Mflv_0295|M.gilvum_PYR-GCK TDWAGSSMRIAP-VREEYAATVGAAAS-LSDPN-VLGASDPAKVAGLLLD
MAV_4982|M.avium_104 TEWAGSSMAVAT-VSPDYESTVGAMNRRRAGFN-RNAPGDPARAAHAIIE
MMAR_1614|M.marinum_M TDFAGRSLVQSTRMINDYAATAGQRRKENDTMH-GNQPGDPAKAAAAIIT
MUL_3423|M.ulcerans_Agy99 TDFAGRSLVQSTRMINDYAATAGQRRKENDTMH-GNQPGDPAKAAAAIIT
MSMEG_3451|M.smegmatis_MC2_155 TGFAS-AMQYTVESEPYRQTAVGQTRRVLENADDTAFAGDPAKIAAVIYD
Mb3083c|M.bovis_AF2122/97 TPLVNTVEIAGVDRDDPRVNRWVERFSGHAVTP--EKAADKILAGVTRNR
Rv3057c|M.tuberculosis_H37Rv TPLVNTVEIAGVDRDDPRVNRWVERFSGHAVTP--EKAADKILAGVTRNR
MLBr_01740|M.leprae_Br4923 TPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSA--ERAAEKILAGVAKNR
MAB_1305|M.abscessus_ATCC_1997 TGIETRRNRIVP-DGSPYRDAFRTVDAAMAARE--EHGTATDELGRLVVD
* .
TH_3670|M.thermoresistible__bu VVDAEKPPLRVFFGELPLQIVNADYQSRLQTWEEWQPIAVLAQG------
Mvan_0982|M.vanbaalenii_PYR-1 VVDAPEPPLRVFFGELPLELARADYESRLANWEKWQPVAIEAQG------
Mflv_0295|M.gilvum_PYR-GCK VIGMPDPPRRLLVGPDAYRYATAAGRDLLAVDERWRTLSMSTAADDVSPE
MAV_4982|M.avium_104 VVIADDPPLRLLLGSDALSAALAKSHQQIAEANRWAELSKSIDYPPVATP
MMAR_1614|M.marinum_M AVESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQLTAGTNLTP----
MUL_3423|M.ulcerans_Agy99 AVESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQLTAGTNLTP----
MSMEG_3451|M.smegmatis_MC2_155 STRNPDPPLRLTLGDDSYHAIRVGLTERLAALDESRELSASVAFTD----
Mb3083c|M.bovis_AF2122/97 YLVYTSADIRALYAFKRYAWWPYTLVMRRVNVFFTRALRPGP--------
Rv3057c|M.tuberculosis_H37Rv YLVYTSADIRALYAFKRYAWWPYTLVMRRVNVFFTRALRPGP--------
MLBr_01740|M.leprae_Br4923 YLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRALRPSPATMRCVEP
MAB_1305|M.abscessus_ATCC_1997 VALSPSPKPLYAKGSNAPIIMTAQRLLPARLFLKFLARMHGLKVR-----
.
TH_3670|M.thermoresistible__bu -------------------
Mvan_0982|M.vanbaalenii_PYR-1 -------------------
Mflv_0295|M.gilvum_PYR-GCK QLDPLGSASR---------
MAV_4982|M.avium_104 HR---AARSR---------
MMAR_1614|M.marinum_M -------------------
MUL_3423|M.ulcerans_Agy99 -------------------
MSMEG_3451|M.smegmatis_MC2_155 -------------------
Mb3083c|M.bovis_AF2122/97 -------------------
Rv3057c|M.tuberculosis_H37Rv -------------------
MLBr_01740|M.leprae_Br4923 IKVGVYSQPRSGEGGKSGN
MAB_1305|M.abscessus_ATCC_1997 -------------------