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M. ulcerans Agy99 MUL_5027 (ethR)

annotation: TetR family transcriptional regulator
coordinates: 5572863 - 5573510
length: 215

VSTSTASQASLSRGRRSARPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPTFYFYFPSKEA
VLLTLLDRVVNEADAALDNLAQAPDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELWSTF
MQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFLAEEPSVPETHVVDTLVHVWVSSI
YGAAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_5027ethR-100% (215)TetR family transcriptional regulator
M. ulcerans Agy99MUL_3401-5e-1225.74% (202) TetR family transcriptional regulator
M. ulcerans Agy99MUL_3708-2e-0925.48% (208) AcrR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3885ethR3e-9277.78% (216) transcriptional regulatory repressor protein (TETR-family)
M. gilvum PYR-GCKMflv_0963-1e-6358.69% (213) TetR family transcriptional regulator
M. tuberculosis H37RvRv3855ethR3e-9277.78% (216) transcriptional regulatory repressor protein (TETR-family)
M. leprae Br4923MLBr_00064-2e-8171.16% (215) putative transcriptional regulator
M. abscessus ATCC 19977MAB_0984c-2e-5651.74% (201) TetR family transcriptional regulator
M. marinum MMMAR_5405ethR1e-11798.14% (215) TetR family transcriptional regulator
M. avium 104MAV_0173-6e-6760.29% (209) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_6441-1e-6659.33% (209) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_1150-9e-7263.72% (215) TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR
M. vanbaalenii PYR-1Mvan_5684-7e-7363.38% (213) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MUL_5027|M.ulcerans_Agy99           -MSTSTASQAS---------LSRGRRSARPSGDERELAILNTAEKLLEDR
MMAR_5405|M.marinum_M               MVSTSTASQAS---------PSRGRRSARPSGDERELAILNTAEKLLEDR
Mb3885|M.bovis_AF2122/97            -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
Rv3855|M.tuberculosis_H37Rv         -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
MLBr_00064|M.leprae_Br4923          -MINSTAGQTS---------QSRSRRSTRPSGDDRELAILATAEQLLEDR
Mvan_5684|M.vanbaalenii_PYR-1       -MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLADR
Mflv_0963|M.gilvum_PYR-GCK          -MSSTTRTG-------------RGRRAARPSGDDRESAILTTAEQLLEQR
TH_1150|M.thermoresistible__bu      -MSTASPVRS------------RGRRSTRPSGDDRELAILTTAEKLLAER
MAV_0173|M.avium_104                -MTTAGQTRAL-----------RGRRAIRPTGDEREQAILATALRLLETR
MSMEG_6441|M.smegmatis_MC2_155      -MTTASQTRTP-----------RGRRSARPSGDDREAAILATAQRLLETK
MAB_0984c|M.abscessus_ATCC_199      -MTKPAT---------------RGRKTTRPSGDERIQAILATAEELLGKR
                                     : ..                 *.*:: **:**:*  *** ** .**  :

MUL_5027|M.ulcerans_Agy99           PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
MMAR_5405|M.marinum_M               PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
Mb3885|M.bovis_AF2122/97            PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
Rv3855|M.tuberculosis_H37Rv         PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
MLBr_00064|M.leprae_Br4923          PLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETL
Mvan_5684|M.vanbaalenii_PYR-1       SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
Mflv_0963|M.gilvum_PYR-GCK          PLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRVIAEANARADAA
TH_1150|M.thermoresistible__bu      PLAEISVDDLAKGAGLSRPTFYFYFPSKDAVLLALVERVIAEADQRADAA
MAV_0173|M.avium_104                PFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLEPVIARADAEFDGA
MSMEG_6441|M.smegmatis_MC2_155      KFAEISVDDLAKGAGISRPTFYFYFPSKEAVLLSLIDPLIKRADSGFDNA
MAB_0984c|M.abscessus_ATCC_199      PLADVSVDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASI
                                     :  :*** **:.**:********* **::*:*:* : :. .*:      

MUL_5027|M.ulcerans_Agy99           AQA---PDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELW
MMAR_5405|M.marinum_M               AQA---PDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISAEVRELW
Mb3885|M.bovis_AF2122/97            AENP--ADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELW
Rv3855|M.tuberculosis_H37Rv         AENP--ADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELW
MLBr_00064|M.leprae_Br4923          IKN---RDNKRGNKWRTGINVFFETFGSHKAVTCAGQVTRDN-TEVRKLW
Mvan_5684|M.vanbaalenii_PYR-1       IAE---RSSDRRTIWRRGINVFFETFGAHRAVCATTVGVKSTNSEARELW
Mflv_0963|M.gilvum_PYR-GCK          LGGRDDRPLEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPNNPEVQRVW
TH_1150|M.thermoresistible__bu      LNGMDARAVDPAGVWR-AINALFETFGAHRAVTLAGAAARTTNTEVDALW
MAV_0173|M.avium_104                VQR---LPTDPRRVWRNGIKAFFTAFSSHRALARAATEALATSSELRSVW
MSMEG_6441|M.smegmatis_MC2_155      VES---MPADPQRAIRRGIEIFFNSFGSHPATARAGTEALKSSPEFKEFW
MAB_0984c|M.abscessus_ATCC_199      DPA---AMTSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRW
                                             .     :  *:  * :*.:* *             *    *

MUL_5027|M.ulcerans_Agy99           STFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFL
MMAR_5405|M.marinum_M               STFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFL
Mb3885|M.bovis_AF2122/97            STFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA
Rv3855|M.tuberculosis_H37Rv         STFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA
MLBr_00064|M.leprae_Br4923          STFMQKWISYTAAVIDAERKRGVAPDTLPATELATALNLMNERALFASFT
Mvan_5684|M.vanbaalenii_PYR-1       SRSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTATFT
Mflv_0963|M.gilvum_PYR-GCK          SHFMQKWIDYTAASIRAERERGAAPDTLPAEDLAIALNLMNERIMLSAFA
TH_1150|M.thermoresistible__bu      SRFMKKWIDYTAESIRAERERGAAPDTIPAEDLAVSLNLMNERTMFAAFA
MAV_0173|M.avium_104                SGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALS
MSMEG_6441|M.smegmatis_MC2_155      SGLMQKWIAATAALITAERERGAAPDTIPALDLATSLNLMNERTMMAALA
MAB_0984c|M.abscessus_ATCC_199      SEVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFT
                                    *   :.*:   :  * ***  *.** .:** ::: :** :*:  : ::: 

MUL_5027|M.ulcerans_Agy99           AEEPSVPETHVVDTLVHVWVSSIYGAAR----
MMAR_5405|M.marinum_M               AEEPSVPETHVVDTLVHIWVSSIYGEAR----
Mb3885|M.bovis_AF2122/97            GEQPSVPEARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv         GEQPSVPEARVLDTLVHIWVTSIYGENR----
MLBr_00064|M.leprae_Br4923          AEQPHVPESRVLDTLVHIWVSSIYNEIR----
Mvan_5684|M.vanbaalenii_PYR-1       GHQPAIPDDRVLDNLVHIWTTSIYGKTD----
Mflv_0963|M.gilvum_PYR-GCK          SEQAAVTADRLVGTLAHIWVSSIYGTPRA---
TH_1150|M.thermoresistible__bu      DEKPAVPEDRIVDTLAHIWLTSIYGTGR----
MAV_0173|M.avium_104                AETPAVAEDRVVDTLTHIWVSSIYGESG----
MSMEG_6441|M.smegmatis_MC2_155      DEQPGVAPEKVVATLTHIWLNSIYGTLPVGTA
MAB_0984c|M.abscessus_ATCC_199      GQQPAVDDGKVVDTLLHVWLNAIYGGVCANS-
                                     . . :   ::: .* *:* .:**.