For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MYDRRVPSHEGQSPRRRTTPRKGDLREAAILDAAERQLSDRGAERITVETIATAAGITRGALYFYFASKN DVLAALVQRTADAVVAAIENADQTAPEDPREALRQGLDRTAEAWGEHGAVMRAAVELSPSVPLIETCWHA ALAAAGGATCRVLVRAGVPDEDGPHGAQAISTALVLMTERYFYRAFTQGTSLTDAARTLADIWLAVLPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1967 | - | - | 100% (209) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3425 | - | 8e-37 | 47.47% (198) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4022 | - | 2e-29 | 38.97% (195) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 3e-17 | 32.50% (200) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_0963 | - | 3e-17 | 33.17% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 3e-17 | 32.50% (200) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_01070 | - | 5e-19 | 32.52% (206) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0984c | - | 4e-14 | 29.38% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5405 | ethR | 7e-17 | 30.88% (204) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1977 | - | 9e-36 | 44.39% (196) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3269 | - | 5e-18 | 34.41% (186) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_5027 | ethR | 8e-17 | 30.39% (204) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5684 | - | 8e-17 | 34.48% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3885|M.bovis_AF2122/97 ---MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLE
Rv3855|M.tuberculosis_H37Rv ---MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLE
MMAR_5405|M.marinum_M --MVSTSTASQAS---------PSRGRRSARPSGDERELAILNTAEKLLE
MUL_5027|M.ulcerans_Agy99 ---MSTSTASQAS---------LSRGRRSARPSGDERELAILNTAEKLLE
Mvan_5684|M.vanbaalenii_PYR-1 ---MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLA
Mflv_0963|M.gilvum_PYR-GCK ---MSSTTR-------------TGRGRRAARPSGDDRESAILTTAEQLLE
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVP--------ASRGRRSSQLSGDDREQAILAVAERLLA
MAB_0984c|M.abscessus_ATCC_199 ---MTKPAT---------------RGRKTTRPSGDERIQAILATAEELLG
MSMEG_1967|M.smegmatis_MC2_155 ---MYDRRVPSHEG--------QSPRRRTTPRKGDLREAAILDAAERQLS
MAV_1977|M.avium_104 ----------------------MTRRRAGEPRKGDLREAAILDAAEELLG
TH_3269|M.thermoresistible__bu ---MAQHGLSVRS-----------PTDRRQPLRSDQRRTAILAALDEQLR
.* * *** . :. *
Mb3885|M.bovis_AF2122/97 DRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQ
Rv3855|M.tuberculosis_H37Rv DRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQ
MMAR_5405|M.marinum_M DRPMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALD
MUL_5027|M.ulcerans_Agy99 DRPMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALD
Mvan_5684|M.vanbaalenii_PYR-1 DRSLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALA
Mflv_0963|M.gilvum_PYR-GCK QRPLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRVIAEANARAD
MLBr_01070|M.leprae_Br4923 ERPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVE
MAB_0984c|M.abscessus_ATCC_199 KRPLADVSVDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVA
MSMEG_1967|M.smegmatis_MC2_155 DRGAERITVETIATAAGITRGALYFYFASKNDVLAALVQRTADAVVAAIE
MAV_1977|M.avium_104 AIGYDAMTIADIAARAGITRGALYFYFGSKQEVITALFARTVAVLHEKSR
TH_3269|M.thermoresistible__bu VTGFERLNIAEVARQAGVTRSAFYFYFENKAAAVAALLDPMYDDVFAAND
..: :* **::* ::**** .* .: :*
Mb3885|M.bovis_AF2122/97 TLAENPADTDRE--NMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAE
Rv3855|M.tuberculosis_H37Rv TLAENPADTDRE--NMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAE
MMAR_5405|M.marinum_M NLAQAP-DVDHV--TMWRNGINVFFETFGSHRAVVQGGQGVRSISAEVRE
MUL_5027|M.ulcerans_Agy99 NLAQAP-DVDHV--TMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRE
Mvan_5684|M.vanbaalenii_PYR-1 QLIAER-SSDRR--TIWRRGINVFFETFGAHRAVCATTVGVKSTNSEARE
Mflv_0963|M.gilvum_PYR-GCK AALGGRDDRPLEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPNNPEVQR
MLBr_01070|M.leprae_Br4923 ALAEQLPADPAA---VWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRR
MAB_0984c|M.abscessus_ATCC_199 SIDPAAMTSPAQ---YWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQ
MSMEG_1967|M.smegmatis_MC2_155 NADQTAPEDPRE---ALRQGLDRTAEAWGEHGAVMRAAVELSPSVPLIET
MAV_1977|M.avium_104 AATEDAASG-AK---AIDTAMRRTEDLWREHGVVMRTAIDLAATVPQLDA
TH_3269|M.thermoresistible__bu LLTADG--DPRQ---RIRAMIETLLDTGERHRYLLQAMLEARAVSSSVRT
: : * :
Mb3885|M.bovis_AF2122/97 LWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFAS
Rv3855|M.tuberculosis_H37Rv LWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFAS
MMAR_5405|M.marinum_M LWSTFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSAS
MUL_5027|M.ulcerans_Agy99 LWSTFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSAS
Mvan_5684|M.vanbaalenii_PYR-1 LWSRSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTAT
Mflv_0963|M.gilvum_PYR-GCK VWSHFMQKWIDYTAASIRAERERGAAPDTLPAEDLAIALNLMNERIMLSA
MLBr_01070|M.leprae_Br4923 LWSTVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAAT
MAB_0984c|M.abscessus_ATCC_199 RWSEVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRAT
MSMEG_1967|M.smegmatis_MC2_155 CWHAALAAAGGATCRVLVRAG-VPDEDGPHGAQAISTALVLMTERYFYRA
MAV_1977|M.avium_104 LWKQTADIFVVAITAILEHMG-VPAGKGPDKSAAIAEALCWMIERNFYQA
TH_3269|M.thermoresistible__bu LWDTARESFVPAVAAMIRTERSAGRAPDGCDPVVLATALLEFNDRLLERF
* : . :: ** : : :
Mb3885|M.bovis_AF2122/97 FAGEQPSVPEARVLDTLVHIWVTSIYGENR--------------------
Rv3855|M.tuberculosis_H37Rv FAGEQPSVPEARVLDTLVHIWVTSIYGENR--------------------
MMAR_5405|M.marinum_M FLAEEPSVPETHVVDTLVHIWVSSIYGEAR--------------------
MUL_5027|M.ulcerans_Agy99 FLAEEPSVPETHVVDTLVHVWVSSIYGAAR--------------------
Mvan_5684|M.vanbaalenii_PYR-1 FTGHQPAIPDDRVLDNLVHIWTTSIYGKTD--------------------
Mflv_0963|M.gilvum_PYR-GCK FASEQAAVTADRLVGTLAHIWVSSIYGTPRA-------------------
MLBr_01070|M.leprae_Br4923 FSDEKPLIPDKKVIDTLVHIWLASIYGS----------------------
MAB_0984c|M.abscessus_ATCC_199 FTGQQPAVDDGKVVDTLLHVWLNAIYGGVCANS-----------------
MSMEG_1967|M.smegmatis_MC2_155 FT--QGTS-LTDAARTLADIWLAVLPS-----------------------
MAV_1977|M.avium_104 SR--VSPARLTRARQTCTEIWLRVAS------------------------
TH_3269|M.thermoresistible__bu TAG--TALSRQQLRDGAEAVWLGSIYPGPIGGPGPRPDPRPDRHPESTPS
:*
Mb3885|M.bovis_AF2122/97 ---
Rv3855|M.tuberculosis_H37Rv ---
MMAR_5405|M.marinum_M ---
MUL_5027|M.ulcerans_Agy99 ---
Mvan_5684|M.vanbaalenii_PYR-1 ---
Mflv_0963|M.gilvum_PYR-GCK ---
MLBr_01070|M.leprae_Br4923 ---
MAB_0984c|M.abscessus_ATCC_199 ---
MSMEG_1967|M.smegmatis_MC2_155 ---
MAV_1977|M.avium_104 ---
TH_3269|M.thermoresistible__bu SRF