For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
WFNGSMTPERSAHSEPANPVRKRHRMVDRVAGILELAARNHDGLTLTELARLLDAPLSSLQGLVNGLVAA GYLDEHDRRYRLGGAPYLLNLMAGRHLVTQVGHQELEAVHADAGLTTLLSVVVGQGVFYVDSCSSTPRYD YLAKNLVRRSLIRTSSGWVLLAGFARRDLWSYLGSLPAEDDANRERFLNTLETIQETGVCAAPHISDVAD GVAVAVREGGRTVAAVSVVGPHEEIHSRRDELVDLLTSHRRRWEQAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3396 | - | - | 100% (258) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_5933 | - | 3e-05 | 33.66% (101) | hypothetical protein MSMEG_5933 |
| M. smegmatis MC2 155 | MSMEG_2483 | - | 5e-05 | 25.55% (227) | transcriptional regulator, IclR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1802c | - | 2e-06 | 25.76% (229) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3087 | - | 4e-07 | 27.78% (216) | transcriptional regulator, TrmB |
| M. tuberculosis H37Rv | Rv1773c | - | 2e-06 | 25.76% (229) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0077 | - | 8e-05 | 26.24% (221) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 2e-06 | 27.97% (236) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3251 | - | 4e-06 | 26.05% (215) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0155 | - | 4e-07 | 25.78% (225) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0077|M.abscessus_ATCC_1997 --------MTITADSATP----------------SAVIDRVSLLLDAFD-
TH_3251|M.thermoresistible__bu --------MTATLDQPTPNTTVKRTGTERTGETPSAVLDRISLVLDAFD-
Mb1802c|M.bovis_AF2122/97 --------MPPTEGK----STTNR-------DEGIQVLRRAVAALDEIAA
Rv1773c|M.tuberculosis_H37Rv --------MPPTEGK----STTNR-------DEGIQVLRRAVAALDEIAA
Mvan_0155|M.vanbaalenii_PYR-1 --------MPGADQNGRIDATEGR-------DDGLQVLRRAAAALDEIAT
Mflv_3087|M.gilvum_PYR-GCK --------MAQHDKTSTTSPTDA--------PAAVQSVDRALQVLEIVA-
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDP--------APTVQSVDRALLVLELLA-
MSMEG_3396|M.smegmatis_MC2_155 --MWFNGSMTPERSAHSEPANPVR--------KRHRMVDRVAGILELAAR
: : * *:
MAB_0077|M.abscessus_ATCC_1997 GPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLRRD-GRD-YELGTRLV
TH_3251|M.thermoresistible__bu GPGRLTLAQVVRRTGLPRSSAHRMLERLVQLRWLRRD-GRD-YELGMRLV
Mb1802c|M.bovis_AF2122/97 EPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSVD-SHGRFALGERLL
Rv1773c|M.tuberculosis_H37Rv EPGHLRLVDLCERLGLAKSTTRRLLVGLVEVGLVSVD-SHGRFALGERLL
Mvan_0155|M.vanbaalenii_PYR-1 APGRLRLVDVGTNLGLAKSTARRLLVALVDVGFAAVD-DSGRYHLGDRLL
Mflv_3087|M.gilvum_PYR-GCK AHGQAGVTEIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIP
MMAR_4423|M.marinum_M DLGKAGVTEVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVS
MSMEG_3396|M.smegmatis_MC2_155 NHDGLTLTELARLLDAPLSSLQGLVNGLVAAGYLDEH--DRRYRLGGAPY
. :.:: . *: :: * : **
MAB_0077|M.abscessus_ATCC_1997 ELGSLAVHQDRLHAAALPMLHELHRAT-GLVVHLSILDGADVVYLEKIGA
TH_3251|M.thermoresistible__bu ELGSLAVHQDRLHRAAIPRLHELHAAT-GLVVHLAVLDGSDVVYLEKVGS
Mb1802c|M.bovis_AF2122/97 GFG--SVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIES
Rv1773c|M.tuberculosis_H37Rv GFG--SVTGAHIAAAFRPTVERVARATDGETVDLSVLRGQRMWFVDQIES
Mvan_0155|M.vanbaalenii_PYR-1 GLT--SADGSTLAARLRPVIERLALAT-GETVDLSVLRGRQMWFVDQIES
Mflv_3087|M.gilvum_PYR-GCK RLAHVAGGQNDLVKLGQAACDMLSAGV-GETANLAVLDADRIVNIVEAIG
MMAR_4423|M.marinum_M RLARARSGHSDLVKLSQDACDKLAADL-GETANLAILDENRAVNIVEAVS
MSMEG_3396|M.smegmatis_MC2_155 LLN-LMAGRHLVTQVGHQELEAVHADA-GLTTLLSVVVGQGVFYVDSCSS
: : . : * .. *::: : . .
MAB_0077|M.abscessus_ATCC_1997 GIGAAVATRIGGRQPAHCTASGKAILAYR--AQILDGC-TALARKTRYSI
TH_3251|M.thermoresistible__bu RLAAAIPTRVGGRRPANCAAVGKAILAYAEDDGVLSGT-GPLPRNTKYSI
Mb1802c|M.bovis_AF2122/97 SYRLRAVSAVGLRFPLNGTANGKAALAALDDADAEA-------ALCRLDP
Rv1773c|M.tuberculosis_H37Rv SYRLRAVSAVGLRFPLNGTANGKAALAALDDADAEA-------ALCRLDP
Mvan_0155|M.vanbaalenii_PYR-1 AHRLRAVSAVGGRFPLHDTANGKAALALMEDD------------------
Mflv_3087|M.gilvum_PYR-GCK PSEITLRTWVGQSCPAYATSSGKVLLAGLDPAELPARIRPPLTEFTDSTL
MMAR_4423|M.marinum_M TAEIALQTWVGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTI
MSMEG_3396|M.smegmatis_MC2_155 TPRYDYLAKNLVRRSLIRTSSGWVLLAGFARRDLWS----YLGSLPAEDD
: . :: * . **
MAB_0077|M.abscessus_ATCC_1997 GSAAQLRPELDKVRGHGVAFDREELQQGIGCVAAPIGSI-GDAVAAVSVC
TH_3251|M.thermoresistible__bu SDPARLRAELAKVRAHGVAFDREESLPGIGCVAAPIGDP-GEAVAAISVC
Mb1802c|M.bovis_AF2122/97 MVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRAL-GDNVIAISVP
Rv1773c|M.tuberculosis_H37Rv MVAEGLRREIVEIRRTGIAFDRNEHTPGISAAAIARRAL-GDNVIAISVP
Mvan_0155|M.vanbaalenii_PYR-1 AIPDGLLDEIAEVRRTGIAYDRDEHTAGISAAGIAVRLP-GGHVVAISVP
Mflv_3087|M.gilvum_PYR-GCK CGLAELQDELAAVRERGWACVREELEVGLNAVAAPVYDVHAQVIAALSVS
MMAR_4423|M.marinum_M VTIDALEAQLAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAAALSVS
MSMEG_3396|M.smegmatis_MC2_155 ANRERFLNTLETIQETGVCAAP-HISDVADGVAVAVREG-GRTVAAVSVV
: : : * . . . .. . . *:**
MAB_0077|M.abscessus_ATCC_1997 GPMTRMT-FDQRLAAPVRMTAMGIWRNVENGPSRVAPTLQPIRPLRCGPA
TH_3251|M.thermoresistible__bu GPMNQMA-FDHRLVAPVRMAALGIWRAMEGARQRVVPTLQQVRPLRPGPT
Mb1802c|M.bovis_AF2122/97 APTARFLEKEQRIIAALRAAAD--------------------SPDWTR--
Rv1773c|M.tuberculosis_H37Rv APTARFLEKEQRIIAALRAAAD--------------------SPDWTR--
Mvan_0155|M.vanbaalenii_PYR-1 APTERFRAQESTIVDALRAAAA--------------------DPVWAGGV
Mflv_3087|M.gilvum_PYR-GCK GPSYRLAVDRFDEVAKQTVAAAEQISR---------------RLGWTTRN
MMAR_4423|M.marinum_M GPAYRLPAADFEEVAQQTIAAADAVSR---------------GLGWTDRI
MSMEG_3396|M.smegmatis_MC2_155 GPHEEIHSRRDELVDLLTSHRR----------------------RWEQAD
.* .:
MAB_0077|M.abscessus_ATCC_1997 ASSTGR-EMNSPALQYA------------
TH_3251|M.thermoresistible__bu AQSLSHSALSHPAQSHPARSHRADTRRFA
Mb1802c|M.bovis_AF2122/97 -----------------------------
Rv1773c|M.tuberculosis_H37Rv -----------------------------
Mvan_0155|M.vanbaalenii_PYR-1 S----------------------------
Mflv_3087|M.gilvum_PYR-GCK -----------------------------
MMAR_4423|M.marinum_M S----------------------------
MSMEG_3396|M.smegmatis_MC2_155 -----------------------------