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MAGSQKPALPHKEALLRSGTKLFYDNGFHGTTVDAVLADAGVPKGSFYHHFGSKDVFGQAVLDRYMEFQR SLLDKWSSKKNLSTPDRLAGYAKDMAHMFVKSGYQRGCLAGKFSTEVAASSEVFREQLSFHIEAWTTQVA ALLASGQEQGDVRSDRSAQEIAEAVLSLIQGTFVLALSTRDKHTLATLVTTLRLLVEPPE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3363 | - | - | 100% (200) | regulatory protein, TetR |
| M. smegmatis MC2 155 | MSMEG_3520 | - | 2e-09 | 24.47% (188) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3360 | - | 1e-08 | 24.10% (195) | transcriptional regulator, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 3e-07 | 32.95% (88) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0944 | - | 2e-15 | 24.70% (166) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 3e-07 | 32.95% (88) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 1e-07 | 32.95% (88) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1494 | - | 3e-10 | 27.46% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0630 | - | 6e-14 | 27.11% (166) | transcriptional regulatory protein |
| M. avium 104 | MAV_0149 | - | 1e-11 | 27.68% (177) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3160 | - | 5e-09 | 29.10% (189) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_1119 | - | 4e-09 | 25.79% (190) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5917 | - | 2e-16 | 25.90% (166) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1494|M.abscessus_ATCC_1997 -------MSTP-----RERMVASAALLIRERGAHATAISDVLEHSGAPRG
MUL_1119|M.ulcerans_Agy99 --MTPPSTSTPKRGGTREKMLISAAQVMRERGAAGVTIDSVLARSGAPRG
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQ-SGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRG
Mflv_0944|M.gilvum_PYR-GCK -------MARPR-TFDEDEVIEAGRDLFWSQGYAATSIDDLSAATGLGRG
Mvan_5917|M.vanbaalenii_PYR-1 -------MARPR-AFDEAAVVEASRDLFWDQGYAATSIDDLSAATGLGRG
MMAR_0630|M.marinum_M -------MARPR-AFDEAVVLSAARDEFRSHGYAATSVDSLAAATGLNRS
Mb0244|M.bovis_AF2122/97 --MAGGTKRLPR-AVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKP
Rv0238|M.tuberculosis_H37Rv --MAGGTKRLPR-AVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKP
MLBr_02568|M.leprae_Br4923 --MAGGAKRIPR-AVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKP
MAV_0149|M.avium_104 -------MATAT----RERFLTAATGLFRRQGYSGTGLKQIVAESRAPLG
MSMEG_3363|M.smegmatis_MC2_155 -----MAGSQKPALPHKEALLRSGTKLFYDNGFHGTTVDAVLADAGVPKG
. .: :. : .* . . : :
MAB_1494|M.abscessus_ATCC_1997 SAYHYFPGGRTQLLSEAVDLAGEYIAGMID--AKPSA--VDALDILVASY
MUL_1119|M.ulcerans_Agy99 SVYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGA--RALLREFVRLW
TH_3160|M.thermoresistible__bu SIYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALRELVGVW
Mflv_0944|M.gilvum_PYR-GCK SLYKAFGDKHSMFLRGLEQYCTEAIAGIRAELRDQDLSAYDRLVAHVRGR
Mvan_5917|M.vanbaalenii_PYR-1 SFYKAFGDKHSMFVRGLELYCTEAVDGIRAELRNPDLSAYDRLVAHIRGA
MMAR_0630|M.marinum_M SLYGSFGDKHRLFLRALDGYCEATLHDVREVLRERGVSARQRLINHVHAI
Mb0244|M.bovis_AF2122/97 MLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSP-KDLLRNTIVSF
Rv0238|M.tuberculosis_H37Rv MLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSP-KDLLRNTIVSF
MLBr_02568|M.leprae_Br4923 MLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSP-KDLLRNTIVSF
MAV_0149|M.avium_104 SLYHFFPGGKQDLAVQAIAHTAERYRELLDRVFAKSTDIGQATVTWFNWA
MSMEG_3363|M.smegmatis_MC2_155 SFYHHFGSKDVFGQAVLDRYMEFQRSLLDKWSSKKNLSTPDRLAGYAKDM
* :
MAB_1494|M.abscessus_ATCC_1997 RKQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIEHSAAVFRRWIDLIA
MUL_1119|M.ulcerans_Agy99 EHLLTDGGFAAGCPVVAAALGPADDEV-----ELAAEAGTILDSWCAALG
TH_3160|M.thermoresistible__bu RDGLEAGDYAVGCPIVAAALGTERAAR--------DVAGVAFADLTGLIS
Mflv_0944|M.gilvum_PYR-GCK AADVVSDNDLRGCLLAKSAAELSSTDP-----EVARHVKRTLDAWLRELT
Mvan_5917|M.vanbaalenii_PYR-1 ADSVASDTDRRGCLLAKSAAELSSTDP-----VVARHVKRTLDAWLRELT
MMAR_0630|M.marinum_M VNGIVADTDRRGCMMSRSSAELAGADP-----DVSGIVERSLEAWRRELA
Mb0244|M.bovis_AF2122/97 LRYIDANRASWIVMYTQATSSQAFAHT-------VREGREQIVQLVAELV
Rv0238|M.tuberculosis_H37Rv LRYIDANRASWIVMYTQATSSQAFAHT-------VREGREQIVQLVAELV
MLBr_02568|M.leprae_Br4923 LRYIDANRASWIVMYIQAMSLPAFAQT-------VREARDQITELVAGLM
MAV_0149|M.avium_104 ARALQETDYADGCPIGTVACEVASSNE-----ALRQATQAVLASWQSRVA
MSMEG_3363|M.smegmatis_MC2_155 AHMFVKSGYQRGCLAGKFSTEVAASSE-----VFREQLSFHIEAWTTQVA
. : :
MAB_1494|M.abscessus_ATCC_1997 DKLVAVGVV-----RTRADELAILMTTSLEGAIIIARSTRDITPIDVVHR
MUL_1119|M.ulcerans_Agy99 RAFVADGFD-----ESTAASLAVTSIAALEGAIMLCRSTRSVEPLRQVGE
TH_3160|M.thermoresistible__bu DKLVSDGMA-----RRRANSVAVLILTAMEGALVLAQARRDPAALDAVVD
Mflv_0944|M.gilvum_PYR-GCK ATISAAQADGDIPSSTEAKALAALILAVLRGMEALRKGGASAATVKATAE
Mvan_5917|M.vanbaalenii_PYR-1 ATISAAQADGDIPSETDAKSMASLLLAVLRGMEALRKGGASAATIKSAAE
MMAR_0630|M.marinum_M DCIAEAQLEGAVAGDGSPQALATVMLSLMQGFEALGKGGVGSAELRAAES
Mb0244|M.bovis_AF2122/97 RAGTRGPLT-----DAEIEMMAVALVG--AGEAVATRLGIGDTDVDEAAE
Rv0238|M.tuberculosis_H37Rv RAGTRGPLT-----DAEIEMMAVALVG--AGEAVATRLGIGDTDVDEAAE
MLBr_02568|M.leprae_Br4923 RVGTRSSRP-----DHEYEIMAGALVG--AGEAMATRLTTGDIAVDEAAE
MAV_0149|M.avium_104 AELIGAGVP-----TAQARRLATFAVASLEGAILLARAHRSTRPLRETGR
MSMEG_3363|M.smegmatis_MC2_155 ALLASGQEQGDVRSDRSAQEIAEAVLSLIQGTFVLALSTRDKHTLATLVT
:* * . :
MAB_1494|M.abscessus_ATCC_1997 QLRTLIEEAGQ----------------
MUL_1119|M.ulcerans_Agy99 QLEFLVKARGFVAQSRLDSE-------
TH_3160|M.thermoresistible__bu ELTLLCSGSAD----------------
Mflv_0944|M.gilvum_PYR-GCK QLVAML---------------------
Mvan_5917|M.vanbaalenii_PYR-1 QAIALLGVQPGTPPTPSMA--------
MMAR_0630|M.marinum_M AALALL-FGAGTDPKP-----------
Mb0244|M.bovis_AF2122/97 MMINLFWLGLKGAPVDR-----LETGH
Rv0238|M.tuberculosis_H37Rv MMINLFWLGLKGAPVDR-----LETGH
MLBr_02568|M.leprae_Br4923 LMINLFWHGLKGAPADRDFGPSIVAG-
MAV_0149|M.avium_104 VVADTLRAATDRG--------------
MSMEG_3363|M.smegmatis_MC2_155 TLRLLVEPPE-----------------