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VASPRERMVRSAAVLIRERGAHPTAIADVLAHSGAPRGSAYHYFPGGRTQLLCEAIDYASDHVTARLDRA TDTFALLDDMVARFRDQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRERAGAAFQRWIARITARLCDD GVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQLREQLTAATGKKDRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3520 | - | - | 100% (195) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3360 | - | 9e-26 | 35.48% (186) | transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_6764 | - | 4e-15 | 25.52% (192) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 2e-61 | 59.16% (191) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 5e-63 | 64.02% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 2e-61 | 59.16% (191) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1494 | - | 4e-60 | 59.57% (188) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0436 | - | 7e-58 | 56.77% (192) | transcriptional regulatory protein |
| M. avium 104 | MAV_4985 | - | 7e-59 | 59.60% (198) | regulatory protein, TetR |
| M. thermoresistible (build 8) | TH_3160 | - | 8e-31 | 41.30% (184) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_1086 | - | 8e-55 | 56.15% (187) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3009 | - | 2e-61 | 61.86% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0202|M.bovis_AF2122/97 -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
MMAR_0436|M.marinum_M -----------MPSPRERMVISAVLLIRERGARATAISDVLQHSGAPRGS
MUL_1086|M.ulcerans_Agy99 ------------------MVISAVLLIRERGACATAISDVLQHSGAPRGS
MAV_4985|M.avium_104 -----------MRSPREKMVVSAALLIRERGAHATAISDVLEHSGAPRGS
MAB_1494|M.abscessus_ATCC_1997 -----------MSTPRERMVASAALLIRERGAHATAISDVLEHSGAPRGS
Mflv_3287|M.gilvum_PYR-GCK -----------MTTPRERMVVSAALLIRERGAHPTAIADVLQHSGAPRGS
Mvan_3009|M.vanbaalenii_PYR-1 -----------MTSPRERMVISAALLIRERGAHPTAIADVLAHSGAPRGS
MSMEG_3520|M.smegmatis_MC2_155 -----------MASPRERMVRSAAVLIRERGAHPTAIADVLAHSGAPRGS
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
*: **. *:*.:*. .*:::*** .*******
Mb0202|M.bovis_AF2122/97 AYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEGGLELLDALIDKYR
Rv0196|M.tuberculosis_H37Rv AYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEGGLELLDALIDKYR
MMAR_0436|M.marinum_M AYHYFPGGRTQLLCEAVDYAG----AHVAKIIGSANRSLDLLDTLIDQYR
MUL_1086|M.ulcerans_Agy99 AYHYFPGGRTQLLCEAVDYAG----AHVAKIIGSATRSLDLLDTLIDQYR
MAV_4985|M.avium_104 AYHYFPGGRTQLLCEAVDFAG----EYVAAVIAGAESGARLLDTLIDTYR
MAB_1494|M.abscessus_ATCC_1997 AYHYFPGGRTQLLSEAVDLAG----EYIAGMIDAKPSAVDALDILVASYR
Mflv_3287|M.gilvum_PYR-GCK AYHYFPGGRTQLLCEAVDYAA----EFMAERLSRASSSLRVLDDLFGYYR
Mvan_3009|M.vanbaalenii_PYR-1 AYHYFPGGRTQLLCEAVDYAG----EFIADRLAQASTTVEALDGLFDGYR
MSMEG_3520|M.smegmatis_MC2_155 AYHYFPGGRTQLLCEAIDYAS----DHVTARLDRATDTFALLDDMVARFR
TH_3160|M.thermoresistible__bu IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALRELVGVWR
**:**.*::**: ** *. :: : * :. :*
Mb0202|M.bovis_AF2122/97 QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
Rv0196|M.tuberculosis_H37Rv QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
MMAR_0436|M.marinum_M EQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQ
MUL_1086|M.ulcerans_Agy99 EQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQ
MAV_4985|M.avium_104 EQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIERAAAAFDRWTDLIAQ
MAB_1494|M.abscessus_ATCC_1997 KQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIEHSAAVFRRWIDLIAD
Mflv_3287|M.gilvum_PYR-GCK TQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAAALTRWSDIIEQ
Mvan_3009|M.vanbaalenii_PYR-1 KQLRDSDFRAGCPVVAVTVEAGDPDKPEQSAAVIERAAAAFARWHDLLAQ
MSMEG_3520|M.smegmatis_MC2_155 DQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRERAGAAFQRWIARITA
TH_3160|M.thermoresistible__bu DGLEAGDYAVGCPIVAAALGTER--------AARDVAGVAFADLTGLISD
* *: .***:.*.:: : :...:
Mb0202|M.bovis_AF2122/97 RFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLL
Rv0196|M.tuberculosis_H37Rv RFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLL
MMAR_0436|M.marinum_M RFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLDVVHRQLRSML
MUL_1086|M.ulcerans_Agy99 RFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLYVVHRQLRSML
MAV_4985|M.avium_104 RFIADGIRRRRAAELAVLATSALEGAIVLARARRDPAPLDVVHRQLRDLL
MAB_1494|M.abscessus_ATCC_1997 KLVAVGVVRTRADELAILMTTSLEGAIIIARSTRDITPIDVVHRQLRTLI
Mflv_3287|M.gilvum_PYR-GCK RLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQLASLI
Mvan_3009|M.vanbaalenii_PYR-1 RLIADGLAQPAATALAMLVLTSFEGAIVVARASRDLAALDLVQEQLRELI
MSMEG_3520|M.smegmatis_MC2_155 RLCDDGVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQLREQL
TH_3160|M.thermoresistible__bu KLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELTLLC
:: *: * :* ::.***:::*: ** .: * :*
Mb0202|M.bovis_AF2122/97 LAELP----ERSR-----
Rv0196|M.tuberculosis_H37Rv LAELP----ERSR-----
MMAR_0436|M.marinum_M LAQLP----EGNRNDHN-
MUL_1086|M.ulcerans_Agy99 LAQLP----EGNRNDHN-
MAV_4985|M.avium_104 AAELAGETAAGRKSRHDR
MAB_1494|M.abscessus_ATCC_1997 EEAGQ-------------
Mflv_3287|M.gilvum_PYR-GCK DART-----VTRRK----
Mvan_3009|M.vanbaalenii_PYR-1 RSHTS---PAARKRAPR-
MSMEG_3520|M.smegmatis_MC2_155 TAATG----KKDRP----
TH_3160|M.thermoresistible__bu SGSAD-------------