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M. smegmatis MC2 155 MSMEG_6764 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 6808750 - 6809331
length: 193

LAELGTRERILQATAELYRRQGMSATGLKQISGAAKAPFGSIYHHFPGGKEAISVEVIRSEGIRYGEFVG
AQLADTDPATGIPQLFESAGRLLQSQDYSEACSIETIALEVASTNEVLRQESATVFENWLTGLARWFGQL
DVDEATSRRLAVITLTALEGAFVLCRTLRSVEPIIAAGQGVQAAVTATLAEKR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6764--100% (193)transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3360-5e-1727.62% (181) transcriptional regulator, putative
M. smegmatis MC2 155MSMEG_3520-4e-1525.52% (192) TetR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0202-7e-1627.32% (194) putative transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3237-3e-7776.84% (190) TetR family transcriptional regulator
M. tuberculosis H37RvRv0196-8e-1627.32% (194) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2447c-2e-4149.73% (187) TetR family transcriptional regulator
M. marinum MMMAR_0470-9e-2331.15% (183) transcriptional regulatory protein
M. avium 104MAV_0149-1e-3342.62% (183) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_3160-2e-1534.91% (169) PUTATIVE putative regulatory protein, TetR
M. ulcerans Agy99MUL_1119-2e-2331.69% (183) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_5860-1e-8178.76% (193) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0202|M.bovis_AF2122/97            MQ-----------GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv         MQ-----------GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
MMAR_0470|M.marinum_M               MTPPSTSTPK-RGGTREKMLISAAQVMRERGAAGVTIDSVLARSGAPRGS
MUL_1119|M.ulcerans_Agy99           MTPPSTSTPK-RGGTREKMLISAAQVMRERGAAGVTIDSVLARSGAPRGS
TH_3160|M.thermoresistible__bu      MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
MSMEG_6764|M.smegmatis_MC2_155      ---------MAELGTRERILQATAELYRRQGMSATGLKQISGAAKAPFGS
Mvan_5860|M.vanbaalenii_PYR-1       ---------MADPSTRSRILDATAELYRRQGMPATGLKQISAAAQAPFGS
Mflv_3237|M.gilvum_PYR-GCK          ---------MTEPTTRDRILDAAAELYRRQGMSATGLKQISAAARAPFGS
MAB_2447c|M.abscessus_ATCC_199      ----------MPANTRDRIVAATCELFRRQGMTGTGLKQIAQSAGAPFGS
MAV_0149|M.avium_104                ----------MATATRERFLTAATGLFRRQGYSGTGLKQIVAESRAPLGS
                                                  .*  :: ::  : *.:*  .. : .:   : ** **

Mb0202|M.bovis_AF2122/97            AYHYFPGGRTQLLCEAVDYAGEHVAAMINEA--EGGLE----LLDALIDK
Rv0196|M.tuberculosis_H37Rv         AYHYFPGGRTQLLCEAVDYAGEHVAAMINEA--EGGLE----LLDALIDK
MMAR_0470|M.marinum_M               VYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGARA----LLREFVRL
MUL_1119|M.ulcerans_Agy99           VYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGARA----LLREFVRL
TH_3160|M.thermoresistible__bu      IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADL--PTALRELVGV
MSMEG_6764|M.smegmatis_MC2_155      IYHHFPGGKEAISVEVIRSEGIRYGEFVGAQLADTDP--A-TGIPQLFES
Mvan_5860|M.vanbaalenii_PYR-1       IYHHFPGGKEAISVEVIRREGIRYAELVGAQLADTDP--L-TGIPQLFEK
Mflv_3237|M.gilvum_PYR-GCK          IYHHFPGGKEAISAEVIRSEGIRYAAFVGAQLADINP--A-NGIEAVFAS
MAB_2447c|M.abscessus_ATCC_199      IYHFFPGGKAQLADEAIRAAGAMYRDLVLAVFDQNGPDLA-ATIRTAFAA
MAV_0149|M.avium_104                LYHFFPGGKQDLAVQAIAHTAERYRELLDRVFAKSTD-IG-QATVTWFNW
                                     *:.** *:  :  :.    .      :     .             .  

Mb0202|M.bovis_AF2122/97            YRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLT
Rv0196|M.tuberculosis_H37Rv         YRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLT
MMAR_0470|M.marinum_M               WEHLLTDGGFAAGCPVVAAALGPADDE-----VELAAEAGTILDSWCAAL
MUL_1119|M.ulcerans_Agy99           WEHLLTDGGFAAGCPVVAAALGPADDE-----VELAAEAGTILDSWCAAL
TH_3160|M.thermoresistible__bu      WRDGLEAGDYAVGCPIVAAALGTER--------AARDVAGVAFADLTGLI
MSMEG_6764|M.smegmatis_MC2_155      AGRLLQSQDYSEACSIETIALEVASTN-----EVLRQESATVFENWLTGL
Mvan_5860|M.vanbaalenii_PYR-1       AGRDLEAQDYSEACSIETIALEVASTN-----ERLRVEAAEVFQSWLTGL
Mflv_3237|M.gilvum_PYR-GCK          AAELLESQDYSEACSIETIALEVASTN-----ERLRGEAAEVFETWLHQL
MAB_2447c|M.abscessus_ATCC_199      AADNLIATDYTDACPIATIALEVASTD-----EDLRHATAEVFTDWIEQG
MAV_0149|M.avium_104                AARALQETDYADGCPIGTVACEVASSN-----EALRQATQAVLASWQSRV
                                        *   .:  .*.: : :                  :   :       

Mb0202|M.bovis_AF2122/97            AQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRN
Rv0196|M.tuberculosis_H37Rv         AQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRN
MMAR_0470|M.marinum_M               GRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSAEPLRQVGEQLEF
MUL_1119|M.ulcerans_Agy99           GRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSVEPLRQVGEQLEF
TH_3160|M.thermoresistible__bu      SDKLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELTL
MSMEG_6764|M.smegmatis_MC2_155      ARWFGQLDVDEATSRRLAVITLTALEGAFVLCRTLRSVEPIIAAGQGVQA
Mvan_5860|M.vanbaalenii_PYR-1       AAWFGRLALTEPECRRLAMITLTALEGAFVLCRTLRSIDPIIAAGHGVQA
Mflv_3237|M.gilvum_PYR-GCK          AGWFGQLDIGDEQSRRLATVMLTALEGAFVLCRTLRSVEPMLIAGHGVQA
MAB_2447c|M.abscessus_ATCC_199      TERIADTGLPPGTRRRLILGFITGLEGAFVLSRALRDPEPLFAAGETVAA
MAV_0149|M.avium_104                AAELIGAGVPTAQARRLATFAVASLEGAILLARAHRSTRPLRETGRVVAD
                                       :    .       :     : :***::*.:  *.  .:  .   :  

Mb0202|M.bovis_AF2122/97            LLLAE-LPERSR----
Rv0196|M.tuberculosis_H37Rv         LLLAE-LPERSR----
MMAR_0470|M.marinum_M               LVKARGFVAQSRLDSE
MUL_1119|M.ulcerans_Agy99           LVKARGFVAQSRLDSE
TH_3160|M.thermoresistible__bu      LCSGS---AD------
MSMEG_6764|M.smegmatis_MC2_155      AVTATLAEKR------
Mvan_5860|M.vanbaalenii_PYR-1       AVRAAATTRRS-----
Mflv_3237|M.gilvum_PYR-GCK          AVHAVLASAQ------
MAB_2447c|M.abscessus_ATCC_199      AATSALAALATHAE--
MAV_0149|M.avium_104                TLRAATDRG-------
                                       .