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MSPRTSDARERMLDSASTLIREHGASGTSLDDILRHSRAPRGSVYHHFPGGRAQLIEEVVDRAGGALAAI LGDAGDATPATTFDVFISTWKAGLEASGFRAGCPVLAVAVETNDDAPQLTEAAARAFGSWRDALNTVLRH QGVPPARARRLATLIVAAVEGAVALSRVERNTQPIDDVARELRALIRQATDAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0275 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3009 | - | 1e-34 | 44.92% (187) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5860 | - | 1e-21 | 32.42% (182) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 3e-37 | 45.11% (184) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 4e-35 | 44.92% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 3e-37 | 45.11% (184) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1494 | - | 5e-38 | 45.03% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0436 | - | 1e-35 | 43.17% (183) | transcriptional regulatory protein |
| M. avium 104 | MAV_4985 | - | 6e-38 | 46.96% (181) | regulatory protein, TetR |
| M. smegmatis MC2 155 | MSMEG_3520 | - | 3e-36 | 45.99% (187) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3160 | - | 5e-28 | 37.89% (190) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_1119 | - | 4e-33 | 37.63% (186) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0202|M.bovis_AF2122/97 -----------MQGP-----RERMVVSAALLIRERGAHATAISDVLQHSG
Rv0196|M.tuberculosis_H37Rv -----------MQGP-----RERMVVSAALLIRERGAHATAISDVLQHSG
MMAR_0436|M.marinum_M -----------MPSP-----RERMVISAVLLIRERGARATAISDVLQHSG
MAV_4985|M.avium_104 -----------MRSP-----REKMVVSAALLIRERGAHATAISDVLEHSG
MAB_1494|M.abscessus_ATCC_1997 -----------MSTP-----RERMVASAALLIRERGAHATAISDVLEHSG
Mflv_3287|M.gilvum_PYR-GCK -----------MTTP-----RERMVVSAALLIRERGAHPTAIADVLQHSG
MSMEG_3520|M.smegmatis_MC2_155 -----------MASP-----RERMVRSAAVLIRERGAHPTAIADVLAHSG
Mvan_0275|M.vanbaalenii_PYR-1 -------MSPRTSDA-----RERMLDSASTLIREHGASGTSLDDILRHSR
MUL_1119|M.ulcerans_Agy99 ------MTPPSTSTPKRGGTREKMLISAAQVMRERGAAGVTIDSVLARSG
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQSGP-----RAAMLRSAVALMRRQGVAATSFADVLADSG
. * *: ** ::*.:*. .:: .:* *
Mb0202|M.bovis_AF2122/97 APRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----LELLDAL
Rv0196|M.tuberculosis_H37Rv APRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----LELLDAL
MMAR_0436|M.marinum_M APRGSAYHYFPGGRTQLLCEAVDYAGAHVAKIIGSANRS----LDLLDTL
MAV_4985|M.avium_104 APRGSAYHYFPGGRTQLLCEAVDFAGEYVAAVIAGAESG----ARLLDTL
MAB_1494|M.abscessus_ATCC_1997 APRGSAYHYFPGGRTQLLSEAVDLAGEYIAGMIDAKPSA----VDALDIL
Mflv_3287|M.gilvum_PYR-GCK APRGSAYHYFPGGRTQLLCEAVDYAAEFMAERLSRASSS----LRVLDDL
MSMEG_3520|M.smegmatis_MC2_155 APRGSAYHYFPGGRTQLLCEAIDYASDHVTARLDRATDT----FALLDDM
Mvan_0275|M.vanbaalenii_PYR-1 APRGSVYHHFPGGRAQLIEEVVDRAGGALAAILGDAGDATP--ATTFDVF
MUL_1119|M.ulcerans_Agy99 APRGSVYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGA--RALLREF
TH_3160|M.thermoresistible__bu APRGSIYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALREL
***** *::** *: *:: *. *. :: : : :
Mb0202|M.bovis_AF2122/97 IDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWS
Rv0196|M.tuberculosis_H37Rv IDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWS
MMAR_0436|M.marinum_M IDQYREQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWS
MAV_4985|M.avium_104 IDTYREQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIERAAAAFDRWT
MAB_1494|M.abscessus_ATCC_1997 VASYRKQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIEHSAAVFRRWI
Mflv_3287|M.gilvum_PYR-GCK FGYYRTQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAAALTRWS
MSMEG_3520|M.smegmatis_MC2_155 VARFRDQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRERAGAAFQRWI
Mvan_0275|M.vanbaalenii_PYR-1 ISTWKAGLEASGFRAGCPVLAVAVETN-----DDAPQLTEAAARAFGSWR
MUL_1119|M.ulcerans_Agy99 VRLWEHLLTDGGFAAGCPVVAAALGPA-----DDEVELAAEAGTILDSWC
TH_3160|M.thermoresistible__bu VGVWRDGLEAGDYAVGCPIVAAALGTER--------AARDVAGVAFADLT
. :. * .: .***: *.:: . :. :
Mb0202|M.bovis_AF2122/97 DLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ
Rv0196|M.tuberculosis_H37Rv DLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ
MMAR_0436|M.marinum_M DLIAQRFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLDVVHRQ
MAV_4985|M.avium_104 DLIAQRFIADGIRRRRAAELAVLATSALEGAIVLARARRDPAPLDVVHRQ
MAB_1494|M.abscessus_ATCC_1997 DLIADKLVAVGVVRTRADELAILMTTSLEGAIIIARSTRDITPIDVVHRQ
Mflv_3287|M.gilvum_PYR-GCK DIIEQRLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQ
MSMEG_3520|M.smegmatis_MC2_155 ARITARLCDDGVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQ
Mvan_0275|M.vanbaalenii_PYR-1 DALNTVLRHQGVPPARARRLATLIVAAVEGAVALSRVERNTQPIDDVARE
MUL_1119|M.ulcerans_Agy99 AALGRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSVEPLRQVGEQ
TH_3160|M.thermoresistible__bu GLISDKLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDE
: *. * :* ::.***: :.: *. .: * :
Mb0202|M.bovis_AF2122/97 LRNLLLAELP------ERSR----
Rv0196|M.tuberculosis_H37Rv LRNLLLAELP------ERSR----
MMAR_0436|M.marinum_M LRSMLLAQLP------EGNRNDHN
MAV_4985|M.avium_104 LRDLLAAELAGETAAGRKSRHDR-
MAB_1494|M.abscessus_ATCC_1997 LRTLIEEAGQ--------------
Mflv_3287|M.gilvum_PYR-GCK LASLIDARTV------TRRK----
MSMEG_3520|M.smegmatis_MC2_155 LREQLTAATG------KKDRP---
Mvan_0275|M.vanbaalenii_PYR-1 LRALIRQATD-------AS-----
MUL_1119|M.ulcerans_Agy99 LEFLVKARGF-----VAQSRLDSE
TH_3160|M.thermoresistible__bu LTLLCSGSAD--------------
*