For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_1086 (-)

annotation: transcriptional regulatory protein
coordinates: 1150332 - 1150907
length: 191

MVISAVLLIRERGACATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGAHVAKIIGSATRSLDLL
DTLIDQYREQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQRFVSDGIPLDSA
HELAVTAMSTLEGALLLARVRRDLTPLYVVHRQLRSMLLAQLPEGNRNDHN
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1086--100% (191)transcriptional regulatory protein
M. ulcerans Agy99MUL_1119-1e-2838.80% (183) transcriptional regulatory protein
M. ulcerans Agy99MUL_2793-1e-2333.93% (168) transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0202-2e-8179.14% (187) putative transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3287-2e-5759.67% (181) TetR family transcriptional regulator
M. tuberculosis H37RvRv0196-2e-8179.14% (187) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1494-6e-5760.11% (178) TetR family transcriptional regulator
M. marinum MMMAR_0436-1e-10298.43% (191) transcriptional regulatory protein
M. avium 104MAV_4985-3e-6973.08% (182) regulatory protein, TetR
M. smegmatis MC2 155MSMEG_3520-1e-5456.15% (187) TetR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_3160-1e-2539.33% (178) PUTATIVE putative regulatory protein, TetR
M. vanbaalenii PYR-1Mvan_3009-3e-5760.11% (178) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1086|M.ulcerans_Agy99           ------------------MVISAVLLIRERGACATAISDVLQHSGAPRGS
MMAR_0436|M.marinum_M               -----------MPSPRERMVISAVLLIRERGARATAISDVLQHSGAPRGS
Mb0202|M.bovis_AF2122/97            -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv         -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
MAV_4985|M.avium_104                -----------MRSPREKMVVSAALLIRERGAHATAISDVLEHSGAPRGS
MAB_1494|M.abscessus_ATCC_1997      -----------MSTPRERMVASAALLIRERGAHATAISDVLEHSGAPRGS
Mflv_3287|M.gilvum_PYR-GCK          -----------MTTPRERMVVSAALLIRERGAHPTAIADVLQHSGAPRGS
Mvan_3009|M.vanbaalenii_PYR-1       -----------MTSPRERMVISAALLIRERGAHPTAIADVLAHSGAPRGS
MSMEG_3520|M.smegmatis_MC2_155      -----------MASPRERMVRSAAVLIRERGAHPTAIADVLAHSGAPRGS
TH_3160|M.thermoresistible__bu      MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
                                                      *: **. *:*.:*. .*:::*** .*******

MUL_1086|M.ulcerans_Agy99           AYHYFPGGRTQLLCEAVDYAG----AHVAKIIGSATRSLDLLDTLIDQYR
MMAR_0436|M.marinum_M               AYHYFPGGRTQLLCEAVDYAG----AHVAKIIGSANRSLDLLDTLIDQYR
Mb0202|M.bovis_AF2122/97            AYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEGGLELLDALIDKYR
Rv0196|M.tuberculosis_H37Rv         AYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEGGLELLDALIDKYR
MAV_4985|M.avium_104                AYHYFPGGRTQLLCEAVDFAG----EYVAAVIAGAESGARLLDTLIDTYR
MAB_1494|M.abscessus_ATCC_1997      AYHYFPGGRTQLLSEAVDLAG----EYIAGMIDAKPSAVDALDILVASYR
Mflv_3287|M.gilvum_PYR-GCK          AYHYFPGGRTQLLCEAVDYAA----EFMAERLSRASSSLRVLDDLFGYYR
Mvan_3009|M.vanbaalenii_PYR-1       AYHYFPGGRTQLLCEAVDYAG----EFIADRLAQASTTVEALDGLFDGYR
MSMEG_3520|M.smegmatis_MC2_155      AYHYFPGGRTQLLCEAIDYAS----DHVTARLDRATDTFALLDDMVARFR
TH_3160|M.thermoresistible__bu      IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALRELVGVWR
                                     **:**.*::**: **   *.      ::  :         *  :.  :*

MUL_1086|M.ulcerans_Agy99           EQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQ
MMAR_0436|M.marinum_M               EQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIAQ
Mb0202|M.bovis_AF2122/97            QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
Rv0196|M.tuberculosis_H37Rv         QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
MAV_4985|M.avium_104                EQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIERAAAAFDRWTDLIAQ
MAB_1494|M.abscessus_ATCC_1997      KQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIEHSAAVFRRWIDLIAD
Mflv_3287|M.gilvum_PYR-GCK          TQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAAALTRWSDIIEQ
Mvan_3009|M.vanbaalenii_PYR-1       KQLRDSDFRAGCPVVAVTVEAGDPDKPEQSAAVIERAAAAFARWHDLLAQ
MSMEG_3520|M.smegmatis_MC2_155      DQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRERAGAAFQRWIARITA
TH_3160|M.thermoresistible__bu      DGLEAGDYAVGCPIVAAALGTER--------AARDVAGVAFADLTGLISD
                                      *   *: .***:.*.:: :               :...:         

MUL_1086|M.ulcerans_Agy99           RFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLYVVHRQLRSML
MMAR_0436|M.marinum_M               RFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLDVVHRQLRSML
Mb0202|M.bovis_AF2122/97            RFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLL
Rv0196|M.tuberculosis_H37Rv         RFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLL
MAV_4985|M.avium_104                RFIADGIRRRRAAELAVLATSALEGAIVLARARRDPAPLDVVHRQLRDLL
MAB_1494|M.abscessus_ATCC_1997      KLVAVGVVRTRADELAILMTTSLEGAIIIARSTRDITPIDVVHRQLRTLI
Mflv_3287|M.gilvum_PYR-GCK          RLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQLASLI
Mvan_3009|M.vanbaalenii_PYR-1       RLIADGLAQPAATALAMLVLTSFEGAIVVARASRDLAALDLVQEQLRELI
MSMEG_3520|M.smegmatis_MC2_155      RLCDDGVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQLREQL
TH_3160|M.thermoresistible__bu      KLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELTLLC
                                    ::   *:    *  :*    ::.***:::*:  **  .:  *  :*    

MUL_1086|M.ulcerans_Agy99           LAQLP----EGNRNDHN-
MMAR_0436|M.marinum_M               LAQLP----EGNRNDHN-
Mb0202|M.bovis_AF2122/97            LAELP----ERSR-----
Rv0196|M.tuberculosis_H37Rv         LAELP----ERSR-----
MAV_4985|M.avium_104                AAELAGETAAGRKSRHDR
MAB_1494|M.abscessus_ATCC_1997      EEAGQ-------------
Mflv_3287|M.gilvum_PYR-GCK          DART-----VTRRK----
Mvan_3009|M.vanbaalenii_PYR-1       RSHTS---PAARKRAPR-
MSMEG_3520|M.smegmatis_MC2_155      TAATG----KKDRP----
TH_3160|M.thermoresistible__bu      SGSAD-------------