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STPGSRAVAGAVKTSAGQRAYEWIRDAILSGEFAEGEFIDEVALAARVGTSRTPVREALQRLQVERYVDL LPRRGAQVRVVTAVEMREIYQARFVLESDALRTICQRQAGAPESARQLIEEMEQAGRERNWNRFAQLDQV FHSEIVRHQRNAVIAEMYDALQPRQVRLGTRTLAEAPARLSVIEREHRELIAALDRHDATTSVDVLRQHL REIPELVDAFEGHAQVRSSD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3345 | - | - | 100% (231) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0535 | - | 2e-25 | 34.00% (200) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4042 | - | 5e-19 | 32.74% (223) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 6e-08 | 28.96% (183) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4366 | - | 2e-11 | 26.47% (204) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 5e-07 | 43.28% (67) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0068 | - | 2e-27 | 35.41% (209) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2244 | - | 1e-11 | 25.98% (204) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0339 | - | 6e-10 | 31.54% (149) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3038 | - | 2e-17 | 29.27% (205) | PUTATIVE putative transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_1833 | - | 7e-12 | 25.73% (206) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3051 | - | 5e-15 | 28.83% (222) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Mflv_4366|M.gilvum_PYR-GCK ----------------------------------------MTTPEFAARP
MAV_0339|M.avium_104 ----------------------------------------MAAIDISGTV
MSMEG_3345|M.smegmatis_MC2_155 ---------------------------------MSTPGSRAVAGAVKTSA
MAB_0068|M.abscessus_ATCC_1997 -----------------------------------------MIRTVAISA
MMAR_2244|M.marinum_M ----------------------MLEEEAVVIPRADSPDQTCGRLPARGTI
MUL_1833|M.ulcerans_Agy99 ----------------------MLEEEAVVIPRADSPDQTCGRLPARGTV
TH_3038|M.thermoresistible__bu ---------------------------------------MSRTVESNGDA
Mvan_3051|M.vanbaalenii_PYR-1 ---------------------------------MAAPTEEPSRLALPATL
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Mflv_4366|M.gilvum_PYR-GCK ---------QLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
MAV_0339|M.avium_104 R-----------ERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPV
MSMEG_3345|M.smegmatis_MC2_155 G-----------QRAYEWIRDAILSGEFAEGEFIDEVALAARVGTSRTPV
MAB_0068|M.abscessus_ATCC_1997 S-----------EEAYRSVKESILNGDIPGGELLSEGEISARMGCSRTPV
MMAR_2244|M.marinum_M G-----------EQVADLIQESILSGEAKRGAPLREELIADRYQVSRRTV
MUL_1833|M.ulcerans_Agy99 G-----------EQVADLIQESILSGEAKRGSPLREELIADRYQVSRRTV
TH_3038|M.thermoresistible__bu S-----------ERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
Mvan_3051|M.vanbaalenii_PYR-1 V-----------EVAGNRLRDAILSGELAPGEKIIEEQLCADFGISRAPL
: . : *: * * : * .:
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Mflv_4366|M.gilvum_PYR-GCK REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
MAV_0339|M.avium_104 REALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAAWAA
MSMEG_3345|M.smegmatis_MC2_155 REALQRLQVERYVDLLPRRGAQVRVVTAVEMREIYQARFVLESDALRTIC
MAB_0068|M.abscessus_ATCC_1997 REAFLRLETEGWLRLYPKRGALVVPITPEERRHVVDARRVIEGAAAARIA
MMAR_2244|M.marinum_M RDALRVLESNGLVRHQRHKGSTVVDFSAEDITDMYRSREVLELDAAKRWC
MUL_1833|M.ulcerans_Agy99 RDALRVLESNGLVRHQRHKGSTVVDFSAGDITDMYRSREVLELDAAKRWC
TH_3038|M.thermoresistible__bu RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVRLAV
Mvan_3051|M.vanbaalenii_PYR-1 REALRRLAQQGLVEHLPRRGSRVTEWSPTDILQLFELRNVLERHAIESAL
*:*: * : : . * * : : :
Mb0170c|M.bovis_AF2122/97 AHITDVEID---ELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRR
Rv0165c|M.tuberculosis_H37Rv AHITDVEID---ELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRR
Mflv_4366|M.gilvum_PYR-GCK ELITDEQLA---ELERIQDELEAAYDAVDHEAAVRLNHAFHRGVNIAAGS
MAV_0339|M.avium_104 ERIGPEELA---TLRELAAEVVAKSGD---DSIGEANWHFHQMIHRAAHS
MSMEG_3345|M.smegmatis_MC2_155 QR--QAGAP--ESARQLIEEMEQAGRERNWNRFAQLDQVFHSEIVRHQRN
MAB_0068|M.abscessus_ATCC_1997 ERGAPQSLL--SDLSALIEVQLGRAAQGDAAGFAAADVDFHRAIVAKLGN
MMAR_2244|M.marinum_M RAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLDS
MUL_1833|M.ulcerans_Agy99 RAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLDS
TH_3038|M.thermoresistible__bu PQLTEERIAELADLATRMEALLD-RRPLDTHQMSRLNNAFHGIFLAEAGN
Mvan_3051|M.vanbaalenii_PYR-1 PLADLDRDL-----EPVRAALEQMDASSDVLSLDDAHRAFHAAVVGLAKN
. ** .
Mb0170c|M.bovis_AF2122/97 IKLAWFLLNAARYMP---------------AQVFAADPRWGADAVNSHRQ
Rv0165c|M.tuberculosis_H37Rv IKLAWFLLNAARYMG---------------AGVRGRP----AMGRGRGEQ
Mflv_4366|M.gilvum_PYR-GCK PKLAQLMGQITRFAL---------------ESVYPTVEGWPAHSMNDHRV
MAV_0339|M.avium_104 PRLANQIKHAARVVP---------------TNFLTLFPEHEKHSLDEHAQ
MSMEG_3345|M.smegmatis_MC2_155 AVIAEMYDALQPRQV------------RLGTRTLAEAPARLSVIEREHRE
MAB_0068|M.abscessus_ATCC_1997 PLLENFYDSLRERQR------------RMAAAAIGVDPVRVARSVAGHRA
MMAR_2244|M.marinum_M PRVDRFFAAIEAEMLY---------ALAILEASEGEYKTDAAKAFGEHKA
MUL_1833|M.ulcerans_Agy99 PRVDRFFAAIEAEMLY---------ALAILEASEGEYKTDAAKAFGEHKA
TH_3038|M.thermoresistible__bu RHLTAAMQAVVRPALV---------T----LTFQKYSERALRLSMHHHAE
Mvan_3051|M.vanbaalenii_PYR-1 RQLDIALEPILLKLQLPMARNMREEARQHAGPGRRHRPGAADEGIGRHKA
:
Mb0170c|M.bovis_AF2122/97 LIAALRRRDTAAVIEHTVWQFTDGARRLTEALAETEVFG---
Rv0165c|M.tuberculosis_H37Rv SSAADRR---AAPPRHSRR---NRAHRLAVHRWGTQADGGPG
Mflv_4366|M.gilvum_PYR-GCK LLAALRKRDGTAARDAMSEHLCAAAGPLIDHLTTRGVIG---
MAV_0339|M.avium_104 LLDALGDKDVERARAIAERHVLDAGRSLAEWLEQRRDGER--
MSMEG_3345|M.smegmatis_MC2_155 LIAALDRHDATTSVDVLRQHLREIPELVDAFEGHAQVRSSD-
MAB_0068|M.abscessus_ATCC_1997 LVDALAAGDAARFSTELVEHMKVVTEVD--------------
MMAR_2244|M.marinum_M MYEALRDRDEQRSTQLISEHLRINRDVLIRIVAS--------
MUL_1833|M.ulcerans_Agy99 MYEALRDRDEQRSTQLISEHLRINRDVLIRIVAS--------
TH_3038|M.thermoresistible__bu LVEAARARDPEWAEAVMRAHILAARHAGE-------------
Mvan_3051|M.vanbaalenii_PYR-1 ILSALETNDPAAVVTAIRDHGHLHYLGLAP------------
*