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QYFSVMADEPRSPAQLRWLGAAQLLATVRAAPGITRAAAANRLGISSGSATDLVARLRQARLLDEAPAPA QGRGRPTTLLRPHPGGPLVLAADVRATGWRLALAALDGIPRIVAEGVYDDAGLDTALGELADAIGSAYRR KSKQVSALAVSVAGTVSDGKLVQFTPHRRRDVDLSVLTSKLPRRAAIPVLLCNDATLAGLAEARSGAAEV AGTSLHLIVATGIGGTLVVNGEPISGTHGAAGEYGHIPFGDPALTCLCGARGCWDLSVDGRALARHRGDT EPQDPVEYVHRILSGDRDAATQRALAEVATSLGRGIGGLVNLHDPEVVTLGGVGAPLRAAAAHAFDTAYR DGLMNFRRDSPPPVLDAEHGEEGPLHGAVAMALDDVTSPAGLANWVARQNF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3313 | - | - | 100% (402) | xylose repressor, putative |
| M. smegmatis MC2 155 | MSMEG_6022 | - | 9e-20 | 28.57% (322) | xylose repressor, ROK-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0316 | - | 2e-17 | 25.90% (390) | putative NagC regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0669 | - | 4e-15 | 32.85% (207) | sugar kinase |
| M. gilvum PYR-GCK | Mflv_1841 | - | 5e-21 | 27.60% (384) | ROK family protein |
| M. tuberculosis H37Rv | Rv0650 | - | 5e-15 | 32.85% (207) | sugar kinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0987 | - | 1e-14 | 27.55% (323) | carbohydrate kinase |
| M. avium 104 | MAV_4510 | - | 2e-13 | 26.73% (318) | sugar kinase |
| M. thermoresistible (build 8) | TH_4374 | - | 1e-14 | 27.67% (253) | PUTATIVE glucokinase |
| M. ulcerans Agy99 | MUL_0739 | - | 8e-15 | 27.55% (323) | carbohydrate kinase |
| M. vanbaalenii PYR-1 | Mvan_4888 | - | 1e-20 | 27.58% (388) | ROK family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0669|M.bovis_AF2122/97 --------------------------------------------------
Rv0650|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0987|M.marinum_M --------------------------------------------------
MUL_0739|M.ulcerans_Agy99 --------------------------------------------------
MAV_4510|M.avium_104 --------------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_1841|M.gilvum_PYR-GCK ----------MSSPRTAVPTSVGDIYALIRAKRGLTRSEVGALSGLSRTA
Mvan_4888|M.vanbaalenii_PYR-1 ----------MALFRTSSASSVGDVFALIRHKRDLTRTEIGRLTGLSRTA
MSMEG_3313|M.smegmatis_MC2_155 MQYFSVMADEPRSPAQLRWLGAAQLLATVRAAPGITRAAAANRLGISSGS
Mb0669|M.bovis_AF2122/97 -------------------------------------MLTLCLDIGGTKI
Rv0650|M.tuberculosis_H37Rv -------------------------------------MLTLCLDIGGTKI
MMAR_0987|M.marinum_M -------------------------------------MLTLCLDIGGTKV
MUL_0739|M.ulcerans_Agy99 -------------------------------------MLTLCLDIGGTKV
MAV_4510|M.avium_104 -------------------------------------MLTLGLDIGGTKI
TH_4374|M.thermoresistible__bu -------------------------------------VLTLTLDIGGTKL
Mflv_1841|M.gilvum_PYR-GCK VNARVSELTSRGLVVEDQHAPSTGGRPAAVLRFNAAAGIVLTAAVGGSRT
Mvan_4888|M.vanbaalenii_PYR-1 VTARVSELTSRDLVVEREQAPSTGGRPAALLSFNADAGVVLTAAVGGSRT
MSMEG_3313|M.smegmatis_MC2_155 ATDLVARLRQARLLDEAPAPAQGRGRPTTLLRPHPGGPLVLAADVRATGW
:.* : .:
Mb0669|M.bovis_AF2122/97 AAGLADPAGTLVHTAQRPTPAYGGAEQVWAAVAEMIADALGVAG---GAV
Rv0650|M.tuberculosis_H37Rv AAGLADPAGTLVHTAQRPTPAYGGAEQVWAAVAEMIADALGVAG---GAV
MMAR_0987|M.marinum_M AVGLADADGALVHTAQVPTPARCAAEQVWAAVAEAIAEALRVAD---ATV
MUL_0739|M.ulcerans_Agy99 AVGLADADGALVHTAQVPTPARCAAEQVWAAVAEAIAEALRVAD---ATV
MAV_4510|M.avium_104 AAALVDSSGTLVHTAVRPTPNPAPADDVWDVVHALIAEVVRAAD---API
TH_4374|M.thermoresistible__bu AAGLVDGDGGLVHHTHAATPG-GDAEAVWTVLAGLIDDALTRAG---GRV
Mflv_1841|M.gilvum_PYR-GCK RLGVCDLAGDALATADIDQEPGQGPASLMPDIVGRLDLLLSEADRRDARI
Mvan_4888|M.vanbaalenii_PYR-1 RLAVCNLAGDVLTAADIDQEPGLGPQDLMPQVVKGLEVLLAESGHSDA-V
MSMEG_3313|M.smegmatis_MC2_155 RLALAALDG-IPRIVAEGVYDDAGLDTALGELADAIGSAYRRKS---KQV
.: * . : : . :
Mb0669|M.bovis_AF2122/97 GGVGIASAGPIDLHSG-RVSPINIGSWGGFPLRDRVAAAVPGVPVRLGGD
Rv0650|M.tuberculosis_H37Rv GGVGIASAGPIDLHSG-RVSPINIGSWGGFPLRDRVAAAVPGVPVRLGGD
MMAR_0987|M.marinum_M AAVGIASAGPVDLDSG-TVSPINIGSWRGFPLRDRVAAMVPDVPVRLGGD
MUL_0739|M.ulcerans_Agy99 AAVGIASAGPVDLDSG-TVSPINIGSWRGFPLRDRVAAMVPDVPVRLGGD
MAV_4510|M.avium_104 AAVGIASAGPVDLPSG-SVSPINIAGWHRFPLRDKVAAAVPATPVVLGGD
TH_4374|M.thermoresistible__bu RAVGVGSAGPIDLTAG-TVSPINLTAWSRFPLTERVSAALPGVPVRLGGD
Mflv_1841|M.gilvum_PYR-GCK FGVGLSLPGTVDPVRGTSIDTPVLSGWDGAPLFP-YFRDLTPAPVVLGND
Mvan_4888|M.vanbaalenii_PYR-1 YGVGLSLPGTVDQERGSSIDTPVLSGWDGAPLIP-YFRQLTEAPVVLGND
MSMEG_3313|M.smegmatis_MC2_155 SALAVSVAGTVSDGKLVQFTPHRRRDVD-LSVLTSKLPRRAAIPVLLCND
.:.:. .*.:. . . .: . ** * .*
Mb0669|M.bovis_AF2122/97 GVCMALGEHWLGAGRGARFLLGLVVSTGVGGGLVLDGAPCLGRTGNAGHV
Rv0650|M.tuberculosis_H37Rv GVCMALGEHWLGAGRGARFLLGLVVSTGVGGGLVLDGAPCLGRTGNAGHV
MMAR_0987|M.marinum_M GVCMALGEHWLGAGRGARFLLGMVVSTGVGGGLVLGGVPYPGRTGNAGHV
MUL_0739|M.ulcerans_Agy99 GVCMALGEHWLGAGRGARFLLGMVVSTGVGGGLVLGGVPYPGRTGNAGHV
MAV_4510|M.avium_104 GLCMALGEQWLGAGRGARFLLGMVVSTGVGGGLVLDGAPYPGRTGNAGHV
TH_4374|M.thermoresistible__bu GLCMAMGEQWRGAGRGARFVLGIVVSTGVGGGLVLDGMPYQGRTGNAGHV
Mflv_1841|M.gilvum_PYR-GCK ANVIALAEWREGAGRAFDDLLVIKASTGLGAGIILGGVLQVGSIRAAGEF
Mvan_4888|M.vanbaalenii_PYR-1 ANVIALAEWRAGAGRGFDDLLVVKASTGLGAGIIAGGAPQRGAIRAAGEF
MSMEG_3313|M.smegmatis_MC2_155 ATLAGLAEARSGAAEVAGTSLHLIVATGIGGTLVVNGEPISGTHGAAGEY
. .:.* **.. * : .:**:*. :: .* * **.
Mb0669|M.bovis_AF2122/97 GHVVVDPD-GSPCPCGGRGCVETIASGPSLARWARANGWSAPPGAGAKEL
Rv0650|M.tuberculosis_H37Rv GHVVVDPD-GSPCPCGGRGCVETIASGPSLARWARANGWSAPPGAGAKEL
MMAR_0987|M.marinum_M GHVVVDQD-GLRCSCGGRGCVETIAAGPSMVRWARANGWSARPEAGAREL
MUL_0739|M.ulcerans_Agy99 GHVVVDQD-GLRCSCGGRGCVETIAAGPSMVRWARANGWSARPEAGAREL
MAV_4510|M.avium_104 GHVVVELD-GRPCTCGGHGCVETVASGPSMVRWARENGWSAAPGAGARDL
TH_4374|M.thermoresistible__bu GHVVVDPR-GVACSCGGRGCVETMAAGPAMVRWARANGWNAPPDADAEDL
Mflv_1841|M.gilvum_PYR-GCK GHNKTAAAAGRACRCGDVGCLETVAGGWALVRALREDGR---TVENLRDV
Mvan_4888|M.vanbaalenii_PYR-1 GHNKTPAAEGRPCRCGDTGCLETVAGGWALVRTLAQEGR---PVRNLRDL
MSMEG_3313|M.smegmatis_MC2_155 GHIPFGDP-ALTCLCGARGCWDLSVDGRALARHR---GDTEPQDPVEYVH
** . * ** ** : . * ::.* *
Mb0669|M.bovis_AF2122/97 AEAAGAGDPVALRAFRRGAAALAAMIASVGAVCDLDLAVIGGGVAKSGRL
Rv0650|M.tuberculosis_H37Rv AEAAGAGDPVALRAFRRGAAALAAMIASVGAVCDLDLAVIGGGVAKSGRL
MMAR_0987|M.marinum_M AAAAAAGDAVALAAFRRGTRGLAAMIASVGAVCDLDRVVIGGGVAKAGRL
MUL_0739|M.ulcerans_Agy99 AAAAAAGDAVALAAFRRGTRGLAAMIASVGAVCDLDRVVIGGGVAKAGRL
MAV_4510|M.avium_104 AAAAAS-DPLAQKAFHRSADALAAMIASVGAVCDLDVVVIGGGVAQSGPL
TH_4374|M.thermoresistible__bu AAAAAAGVPVAVRAYRRGADALAAAISSVAAVCDLDLVVIGGGVARSGPV
Mflv_1841|M.gilvum_PYR-GCK VVLAHTGDALARRLIRDSGRHVGKVLAAAVNLLNPAALVVAGDVAGAYDI
Mvan_4888|M.vanbaalenii_PYR-1 VELAHSGDALARRQIRDSGRYIGEVLAGAVNLLNPAALVVAGDAAGAYDI
MSMEG_3313|M.smegmatis_MC2_155 RILSGDRDAATQRALAEVATSLGRGIGGLVNLHDPEVVTLGGVGAPLRAA
: . : :. :.. : : .:.* *
Mb0669|M.bovis_AF2122/97 LFEPLRAALAD-HARLDFLAGLRVVPAELGGAAGLVGAARLAAIA-----
Rv0650|M.tuberculosis_H37Rv LFEPLRAALAD-HARLDFLAGLRVVPAELGGAAGLVGAARLAAIA-----
MMAR_0987|M.marinum_M LFDPLRAALAD-YLGLDFLAGLRVVPAELGGQAGLVGAARLAGLG-----
MUL_0739|M.ulcerans_Agy99 LFDPLRAALAD-YLGLDFLAGLRVVPAELGGQAGLVGAARLAGLG-----
MAV_4510|M.avium_104 LFDPLRERLAH-YAGLDFLSGLTVVPGELGGNAGLIGAARLATLARPAGS
TH_4374|M.thermoresistible__bu LFDPLAEALTT-YTGLSFLRGLRVVPARLGATAGLIGAARLAISAC----
Mflv_1841|M.gilvum_PYR-GCK FVAGLRETLYG-NATALATKNLDVLPAALGDRSGGIGSATMVLDEVLGPR
Mvan_4888|M.vanbaalenii_PYR-1 FVAGLRETLYG-NATALATRVLEIRPAQLGDRGGSIGSAMMVLDQVLGPR
MSMEG_3313|M.smegmatis_MC2_155 AAHAFDTAYRDGLMNFRRDSPPPVLDAEHGEEGPLHGAVAMALDDVTSPA
: : . * . *:. :.
Mb0669|M.bovis_AF2122/97 -----------
Rv0650|M.tuberculosis_H37Rv -----------
MMAR_0987|M.marinum_M -----------
MUL_0739|M.ulcerans_Agy99 -----------
MAV_4510|M.avium_104 -----------
TH_4374|M.thermoresistible__bu -----------
Mflv_1841|M.gilvum_PYR-GCK AVDALVTTS--
Mvan_4888|M.vanbaalenii_PYR-1 AVDALVAA---
MSMEG_3313|M.smegmatis_MC2_155 GLANWVARQNF