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MLTLCLDIGGTKIAAGLADPAGTLVHTAQRPTPAYGGAEQVWAAVAEMIADALGVAGGAVGGVGIASAGP IDLHSGRVSPINIGSWGGFPLRDRVAAAVPGVPVRLGGDGVCMALGEHWLGAGRGARFLLGLVVSTGVGG GLVLDGAPCLGRTGNAGHVGHVVVDPDGSPCPCGGRGCVETIASGPSLARWARANGWSAPPGAGAKELAE AAGAGDPVALRAFRRGAAALAAMIASVGAVCDLDLAVIGGGVAKSGRLLFEPLRAALADHARLDFLAGLR VVPAELGGAAGLVGAARLAAIA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0669 | - | - | 100% (302) | sugar kinase |
| M. bovis AF2122 / 97 | Mb0857c | PE_PGRS14 | 1e-07 | 28.16% (316) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1789c | wag22b | 3e-07 | 31.95% (169) | hypothetical protein Mb1789c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5102 | - | 1e-113 | 68.90% (299) | ROK family protein |
| M. tuberculosis H37Rv | Rv0650 | - | 1e-174 | 100.00% (302) | sugar kinase |
| M. leprae Br4923 | MLBr_01023 | ppgK | 4e-05 | 28.19% (149) | polyphosphate glucokinase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0987 | - | 1e-137 | 81.73% (301) | carbohydrate kinase |
| M. avium 104 | MAV_4510 | - | 1e-123 | 72.85% (302) | sugar kinase |
| M. smegmatis MC2 155 | MSMEG_1363 | - | 1e-117 | 71.91% (299) | glucokinase |
| M. thermoresistible (build 8) | TH_4374 | - | 1e-117 | 69.21% (302) | PUTATIVE glucokinase |
| M. ulcerans Agy99 | MUL_0739 | - | 1e-137 | 81.73% (301) | carbohydrate kinase |
| M. vanbaalenii PYR-1 | Mvan_1251 | - | 1e-116 | 71.04% (297) | ROK family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0669|M.bovis_AF2122/97 ----------MLTLCLDIGGTKIAAGLADPAGTLVHTAQRPTPAYGGAEQ
Rv0650|M.tuberculosis_H37Rv ----------MLTLCLDIGGTKIAAGLADPAGTLVHTAQRPTPAYGGAEQ
MMAR_0987|M.marinum_M ----------MLTLCLDIGGTKVAVGLADADGALVHTAQVPTPARCAAEQ
MUL_0739|M.ulcerans_Agy99 ----------MLTLCLDIGGTKVAVGLADADGALVHTAQVPTPARCAAEQ
MAV_4510|M.avium_104 ----------MLTLGLDIGGTKIAAALVDSSGTLVHTAVRPTPNPAPADD
Mflv_5102|M.gilvum_PYR-GCK ----MALSMSDLTLTLDIGGTKLAAGLVDADGNLVRRAQTPTPD-GDAET
Mvan_1251|M.vanbaalenii_PYR-1 --------MNDLVLALDIGGTKIAAGLVDADGTLVHRAQQPTPD-GDAET
MSMEG_1363|M.smegmatis_MC2_155 ---------MTLTLALDIGGTKIAAGLVDDDGALVHQAQLPTPD-GDGEL
TH_4374|M.thermoresistible__bu ----------VLTLTLDIGGTKLAAGLVDGDGGLVHHTHAATPG-GDAEA
MLBr_01023|M.leprae_Br4923 MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEI
*.:. ... : . : : . :
Mb0669|M.bovis_AF2122/97 VWAAVAEMIADALGVAGGAVGGVGIASAGP-IDLHS----GRVSPINIGS
Rv0650|M.tuberculosis_H37Rv VWAAVAEMIADALGVAGGAVGGVGIASAGP-IDLHS----GRVSPINIGS
MMAR_0987|M.marinum_M VWAAVAEAIAEALRVADATVAAVGIASAGP-VDLDS----GTVSPINIGS
MUL_0739|M.ulcerans_Agy99 VWAAVAEAIAEALRVADATVAAVGIASAGP-VDLDS----GTVSPINIGS
MAV_4510|M.avium_104 VWDVVHALIAEVVRAADAPIAAVGIASAGP-VDLPS----GSVSPINIAG
Mflv_5102|M.gilvum_PYR-GCK IWDAVASLLAETRSAADSTIGAVGIASAGP-VDVPA----GTVSPINIAE
Mvan_1251|M.vanbaalenii_PYR-1 VWDTAAALLAETRDAAPGPVSAVGIGSAGP-IDVPG----GTVSPINIAE
MSMEG_1363|M.smegmatis_MC2_155 IWNVVDELVTGALRVADGAVDGVGIAAAGP-IDLPG----GTISPINIVE
TH_4374|M.thermoresistible__bu VWTVLAGLIDDALTRAGGRVRAVGVGSAGP-IDLTA----GTVSPINLTA
MLBr_01023|M.leprae_Br4923 AITSTDATADTPRTSPPSDTAGTTSRHRGFGIDIGGSSIKGGIVDLDIGQ
. . .. * :*: . * : :::
Mb0669|M.bovis_AF2122/97 WGG------FPLRDRVAAAVPGVPVRLGGDGVCMALGEHWLGAGRGARFL
Rv0650|M.tuberculosis_H37Rv WGG------FPLRDRVAAAVPGVPVRLGGDGVCMALGEHWLGAGRGARFL
MMAR_0987|M.marinum_M WRG------FPLRDRVAAMVPDVPVRLGGDGVCMALGEHWLGAGRGARFL
MUL_0739|M.ulcerans_Agy99 WRG------FPLRDRVAAMVPDVPVRLGGDGVCMALGEHWLGAGRGARFL
MAV_4510|M.avium_104 WHR------FPLRDKVAAAVPATPVVLGGDGLCMALGEQWLGAGRGARFL
Mflv_5102|M.gilvum_PYR-GCK WHR------FPIVERVEAAT-GLPVYLGGDGLCMAMGEWWRGAGRNRRFM
Mvan_1251|M.vanbaalenii_PYR-1 WSH------FPIVRRVADLT-GLPVRLGGDGLCMALGEWWRGAGRGAGFL
MSMEG_1363|M.smegmatis_MC2_155 WQR------FPIVDRVAAAT-GLPVRLGGDGLCMALGEHWRGAGRGAQFL
TH_4374|M.thermoresistible__bu WSR------FPLTERVSAALPGVPVRLGGDGLCMAMGEQWRGAGRGARFV
MLBr_01023|M.leprae_Br4923 LIGDRIKLLTPQPATPLAVAKTIAEVVNAFGWTAPLGVTYPGVVTQGVVR
* . :.. * .:* : *. .
Mb0669|M.bovis_AF2122/97 LGLVVSTGVGGGLVLDGAPCLGRTGNAGHVGHVVVDP-DGSPCPCG--GR
Rv0650|M.tuberculosis_H37Rv LGLVVSTGVGGGLVLDGAPCLGRTGNAGHVGHVVVDP-DGSPCPCG--GR
MMAR_0987|M.marinum_M LGMVVSTGVGGGLVLGGVPYPGRTGNAGHVGHVVVDQ-DGLRCSCG--GR
MUL_0739|M.ulcerans_Agy99 LGMVVSTGVGGGLVLGGVPYPGRTGNAGHVGHVVVDQ-DGLRCSCG--GR
MAV_4510|M.avium_104 LGMVVSTGVGGGLVLDGAPYPGRTGNAGHVGHVVVEL-DGRPCTCG--GH
Mflv_5102|M.gilvum_PYR-GCK LGMVVSTGIGGGLVLDGAPFHGRTGNAGHVGHVVVEP-DGDACTCG--GR
Mvan_1251|M.vanbaalenii_PYR-1 LGMVVSTGIGGGLVLDGAPYHGRSGNAGHVGHVVVEP-GGAPCTCG--GR
MSMEG_1363|M.smegmatis_MC2_155 LGMVVSTGVGGGLVLDGAPYDGRTGNAGHAGHVIVELEDGDLCTCG--GH
TH_4374|M.thermoresistible__bu LGIVVSTGVGGGLVLDGMPYQGRTGNAGHVGHVVVDP-RGVACSCG--GR
MLBr_01023|M.leprae_Br4923 TAANVDDSWIGTNARDIISAELNSQEVTILNDADAAGLAEGRYGAGKNNS
. *. . * . . . .: :. ... . .* .
Mb0669|M.bovis_AF2122/97 GCVETIASGPSLARWARANG-------WSAPPGAGAKELAEAAGAGDPVA
Rv0650|M.tuberculosis_H37Rv GCVETIASGPSLARWARANG-------WSAPPGAGAKELAEAAGAGDPVA
MMAR_0987|M.marinum_M GCVETIAAGPSMVRWARANG-------WSARPEAGARELAAAAAAGDAVA
MUL_0739|M.ulcerans_Agy99 GCVETIAAGPSMVRWARANG-------WSARPEAGARELAAAAAAGDAVA
MAV_4510|M.avium_104 GCVETVASGPSMVRWARENG-------WSAAPGAGARDLAAAAAS-DPLA
Mflv_5102|M.gilvum_PYR-GCK GCVETVASGPHLARWARAHG-------WEG---ADARELAEAAGRGEDVA
Mvan_1251|M.vanbaalenii_PYR-1 GCVETVASGPHLARWAHDNG-------WAAAPDADAKDLAEAAGRGDPVA
MSMEG_1363|M.smegmatis_MC2_155 GCVETVASGPNMTRWARRQG-------WQAPADADAKELADAANAGDAVA
TH_4374|M.thermoresistible__bu GCVETMAAGPAMVRWARANG-------WNAPPDADAEDLAAAAAAGVPVA
MLBr_01023|M.leprae_Br4923 GLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQRAASSVKDKY
* : :: *. : . :* : . . **
Mb0669|M.bovis_AF2122/97 LRAFRRGAAALAAMIASVGAVCDLDLAVIGGGVAKSGRLLFEPLRAALAD
Rv0650|M.tuberculosis_H37Rv LRAFRRGAAALAAMIASVGAVCDLDLAVIGGGVAKSGRLLFEPLRAALAD
MMAR_0987|M.marinum_M LAAFRRGTRGLAAMIASVGAVCDLDRVVIGGGVAKAGRLLFDPLRAALAD
MUL_0739|M.ulcerans_Agy99 LAAFRRGTRGLAAMIASVGAVCDLDRVVIGGGVAKAGRLLFDPLRAALAD
MAV_4510|M.avium_104 QKAFHRSADALAAMIASVGAVCDLDVVVIGGGVAQSGPLLFDPLRERLAH
Mflv_5102|M.gilvum_PYR-GCK LRAFARGADAVARTIASVAAVCDLDLVVVGGGVAKAGSLLFDPLHQALRT
Mvan_1251|M.vanbaalenii_PYR-1 LRAFARGADAVARTIASVAAVCDLDLVVVGGGVAKAGALLFDPLRQALTM
MSMEG_1363|M.smegmatis_MC2_155 LAAYRRGARAVAAMIASVGAVCDLDLVVIGGGVAKSGALLFDPIREALKN
TH_4374|M.thermoresistible__bu VRAYRRGADALAAAISSVAAVCDLDLVVIGGGVARSGPVLFDPLAEALTT
MLBr_01023|M.leprae_Br4923 KWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTP-
:: : :: : :: . * : ***::: . : :
Mb0669|M.bovis_AF2122/97 HARLDFLAGLRVVPAELGGAAGLVGAARLAAIA-----
Rv0650|M.tuberculosis_H37Rv HARLDFLAGLRVVPAELGGAAGLVGAARLAAIA-----
MMAR_0987|M.marinum_M YLGLDFLAGLRVVPAELGGQAGLVGAARLAGLG-----
MUL_0739|M.ulcerans_Agy99 YLGLDFLAGLRVVPAELGGQAGLVGAARLAGLG-----
MAV_4510|M.avium_104 YAGLDFLSGLTVVPGELGGNAGLIGAARLATLARPAGS
Mflv_5102|M.gilvum_PYR-GCK YAGLDFLTDLRVVPAELGGDAGLVGAAALAAHHGRFG-
Mvan_1251|M.vanbaalenii_PYR-1 YAGLEFLRGLRVVPAELGGDAGLVGAAALVHDSVRFG-
MSMEG_1363|M.smegmatis_MC2_155 YAGLDFLRTLQVVPAELGGDAGLIGAAALARA------
TH_4374|M.thermoresistible__bu YTGLSFLRGLRVVPARLGATAGLIGAARLAISAC----
MLBr_01023|M.leprae_Br4923 -----------MVAAALQNTAGIVGAAMASTADVTH--
:*.. * **::***