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MTETHTRVDHVAAMTHLDRKPTTFDSYKDRYETIRMERTDGVLELHFHTNGGPLQWSLLAHNEFEDAFLE IGRDRENDVVIMTGTGEEFSGPAIAPGQHPNRRTMTPETYDPIQWEGKQLLPNLLSIEAPVIAAINGPAV RHAEIPLVSDIVLATEDTYFQDTAHFPGGMVPGDGMHIVMPLLMGPTRARYFLLTGQQLSVAEAREIGLV NEVVPRDDLLSRARELAAQLMRQPRLVRRYSRTVLTEDLRQRMHGLLGYGLALEGLARMKS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2948 | - | - | 100% (271) | 6-oxocamphor hydrolase |
| M. smegmatis MC2 155 | MSMEG_5620 | - | 1e-21 | 34.78% (207) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2880 | - | 7e-21 | 33.17% (208) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2698 | echA15 | 4e-18 | 32.49% (237) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4495 | - | 5e-15 | 38.52% (122) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv2679 | echA15 | 5e-18 | 32.49% (237) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-11 | 25.63% (199) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3124 | - | 2e-15 | 33.33% (186) | enoyl-CoA hydratase |
| M. marinum M | MMAR_3510 | echA8_5 | 6e-19 | 31.25% (208) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_1818 | - | 3e-18 | 29.33% (208) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3045 | - | 5e-23 | 35.27% (207) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 3e-18 | 30.77% (208) | enoyl-CoA hydratase, EchA8_5 |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 7e-18 | 32.21% (208) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3510|M.marinum_M ----------------MNTA--LDITTNGPIRTWTINLPD---VGNAITG
MUL_2758|M.ulcerans_Agy99 ----------------MNTA--LDITTNGPIRTWTINLPD---VGNAITG
Mvan_2877|M.vanbaalenii_PYR-1 ---MTPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPH---VGNAITG
Mflv_4495|M.gilvum_PYR-GCK -----------------MTEDLVLTADHDGVRVITLNRPA---ARNALS-
MAB_3124|M.abscessus_ATCC_1997 -----------------MTEPILLTHTEDRICTITLNRPQ---ARNALS-
MLBr_02402|M.leprae_Br4923 -----------------MKYDTILVDGYQRVGIITLNRPQ---ALNALN-
Mb2698|M.bovis_AF2122/97 -----------MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVG-
Rv2679|M.tuberculosis_H37Rv -----------MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVG-
MAV_1818|M.avium_104 ----MTTSEIATLAGYEQFAPWLLVEKRGNVHVVSINRPE---ALNAVT-
TH_3045|M.thermoresistible__bu -------------VKYD-LPDVMTVRADGPIRTVTLDRAA---DLNSVD-
MSMEG_2948|M.smegmatis_MC2_155 MTETHTRVDHVAAMTHLDRKPTTFDSYKDRYETIRMERTDGVLELHFHTN
:: :
MMAR_3510|M.marinum_M -------KDFIAAFEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMAN
MUL_2758|M.ulcerans_Agy99 -------RDFIAAFEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMAN
Mvan_2877|M.vanbaalenii_PYR-1 -------TDFIAAFESAVDTANSDVAVRAVILTGAGKIFSAGGNVKEMAD
Mflv_4495|M.gilvum_PYR-GCK -------RDLIRATYTALTSADDDDAVRAVVLTGADPAFCAGVDLKEAAR
MAB_3124|M.abscessus_ATCC_1997 -------TALGEEIVKAVTAADADENVDVMILTAADPVFCAGVDLKELG-
MLBr_02402|M.leprae_Br4923 -------SQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMAS
Mb2698|M.bovis_AF2122/97 -------PHMHRDLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAE
Rv2679|M.tuberculosis_H37Rv -------PHMHRDLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAE
MAV_1818|M.avium_104 -------EEVHHAFATIWKVLDADTDVKAVVTTGVGKAFSAGGDMVMFGR
TH_3045|M.thermoresistible__bu -------ADLHWALANVWRQLAADTDARVVILTGAGRAFSAGGDLDWITS
MSMEG_2948|M.smegmatis_MC2_155 GGPLQWSLLAHNEFEDAFLEIGRDRENDVVIMTGTGEEFSGPAIAPGQHP
* .:: . *..
MMAR_3510|M.marinum_M RDGMFGLDALEQRQAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLA
MUL_2758|M.ulcerans_Agy99 RDGMFGLDALEQRQAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLA
Mvan_2877|M.vanbaalenii_PYR-1 RQGMFGLDAIAQRHAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLA
Mflv_4495|M.gilvum_PYR-GCK ---------DGLSYFAEFRTQSCIAAVAAMRTPVVGAINGATFTGGLEMA
MAB_3124|M.abscessus_ATCC_1997 ---------------SGDRAESLDPWWPELSKPVIGAINGAAVTGGLELA
MLBr_02402|M.leprae_Br4923 ---------LTFTDAFDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELA
Mb2698|M.bovis_AF2122/97 TIG-----DYQGRLRIMREARDLVLNLVNFDKPVVSAIRGPAVGAGLVVA
Rv2679|M.tuberculosis_H37Rv TIG-----DYQGRLRIMREARDLVLNLVNFDKPVVSAIRGPAVGAGLVVA
MAV_1818|M.avium_104 LIE-----DEVARTYQIHEARTVFLEVINFPKPLVSAVNGPAVGLGCSIA
TH_3045|M.thermoresistible__bu FLT-----DQVARDESIREGAQIIEEMLRFPLPVIAAVNGPAVGLGCSVA
MSMEG_2948|M.smegmatis_MC2_155 NRR---TMTPETYDPIQWEGKQLLPNLLSIEAPVIAAINGPAVRH-AEIP
. *::.*: * :. :.
MMAR_3510|M.marinum_M MMCDIRIASQRASFAE-SFVALGIIPGDGGTWFLQRAIGYERAAEMTLTG
MUL_2758|M.ulcerans_Agy99 MMCDIRIASQRASFAE-SFVALGIIPGDGGTWFLQRAIGYERAAEMTLTG
Mvan_2877|M.vanbaalenii_PYR-1 AMCDIRVASERASFAE-SFVQIGLVPGDGGTWFLQRAIGYERAAEMTLTG
Mflv_4495|M.gilvum_PYR-GCK LGCDFMIASERAVFAD-THARVGILPGGGMTARLPQLVGAAMARRLSMTG
MAB_3124|M.abscessus_ATCC_1997 LACDILIASEKARFAD-THARVGILPTWGLTTLLPLSVGRGLARRMSLTG
MLBr_02402|M.leprae_Br4923 MMCDLLIAADTAKFGQ-PEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTG
Mb2698|M.bovis_AF2122/97 LLADISVAGRAAKIID-GHTKLGVAAGDHAAICWPLLVGMAKAKYYLLTC
Rv2679|M.tuberculosis_H37Rv LLADISVAGRAAKIID-GHTKLGVAAGDHAAICWPLLVGMAKAKYYLLTC
MAV_1818|M.avium_104 LLSDLLVMGENSYLAD-PHVAVGLTAGDGGTAMLPLLIGMMKAKEYVLLG
TH_3045|M.thermoresistible__bu VLCDIVLIAENAYLAD-PHVAVGLVAGDGGAAMWPLLTLVLRSREYLFTG
MSMEG_2948|M.smegmatis_MC2_155 LVSDIVLATEDTYFQDTAHFPGGMVPGDGMHIVMPLLMGPTRARYFLLTG
.*: : : : : *: . : :
MMAR_3510|M.marinum_M DRIDAATALEWGMVSRVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQ
MUL_2758|M.ulcerans_Agy99 DRIDAATALEWGMVSRVVPHGDLLPQAQELAERIVKNPAHALRMAKRLLQ
Mvan_2877|M.vanbaalenii_PYR-1 DRIDAATALEWGLVSRVVAHDELLTAAGELAARIAKNPPHTLRMAKRLLQ
Mflv_4495|M.gilvum_PYR-GCK EVVDAARAERIGLVTEVVAHQHLLQRAIDLAHQIAEVPRPTMRGLKEIYT
MAB_3124|M.abscessus_ATCC_1997 DYLSAEDALRAGLVTEVVAHNELLPAAKRLAATIAGNNQPAVRELLASYR
MLBr_02402|M.leprae_Br4923 RTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVN
Mb2698|M.bovis_AF2122/97 EPLSGEEAERIGLVSICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN
Rv2679|M.tuberculosis_H37Rv EPLSGEEAERIGLVSICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN
MAV_1818|M.avium_104 DRITAPIAEKLNLVTKVVSDDTVLDEALALGERFAALPPQALRSSKVALN
TH_3045|M.thermoresistible__bu DRIPAATAVELGLASRTVPADDLLPEAIRLAERLAAQPAEALRGTKRIVN
MSMEG_2948|M.smegmatis_MC2_155 QQLSVAEAREIGLVNEVVPRDDLLSRARELAAQLMRQPRLVRRYSRTVLT
: * . .:.. * :* * :. : . *
MMAR_3510|M.marinum_M ESRVGSLESTLGMAAAMQPLAHRDPEHQQRIAKWRTR-------------
MUL_2758|M.ulcerans_Agy99 ESRVGSLESTLGMAAAMQPLAHRDPEHQQRIAKWRTRIAKWRTR------
Mvan_2877|M.vanbaalenii_PYR-1 ESRTGVLESTLGMAAAMQPLAHRDPEHAARISRWRSS-------------
Mflv_4495|M.gilvum_PYR-GCK AGASAVVDPALAAEERIAF---AQHRDLEGLGDRFSAVSQRNRDQIGGA-
MAB_3124|M.abscessus_ATCC_1997 RIESELVGNGLQVALDDAHRWIDQNSIAEGVEARRTAIMERGRSQNA---
MLBr_02402|M.leprae_Br4923 RSFESTLAEGLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR-----
Mb2698|M.bovis_AF2122/97 -HWYRMFGPAFETSLGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGA
Rv2679|M.tuberculosis_H37Rv -HWYRMFGPAFETSLGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGA
MAV_1818|M.avium_104 MHLARAAQGVLEYALAEELTSFSTPEFKERVAAFLARSKK----------
TH_3045|M.thermoresistible__bu MYLSQALAGPLQAGFAAEVATMRTAEHRDRLLALRERTR-----------
MSMEG_2948|M.smegmatis_MC2_155 EDLRQRMHGLLGYGLALEGLARMKS-------------------------
:
MMAR_3510|M.marinum_M --
MUL_2758|M.ulcerans_Agy99 --
Mvan_2877|M.vanbaalenii_PYR-1 --
Mflv_4495|M.gilvum_PYR-GCK --
MAB_3124|M.abscessus_ATCC_1997 --
MLBr_02402|M.leprae_Br4923 --
Mb2698|M.bovis_AF2122/97 GS
Rv2679|M.tuberculosis_H37Rv GS
MAV_1818|M.avium_104 --
TH_3045|M.thermoresistible__bu --
MSMEG_2948|M.smegmatis_MC2_155 --