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MTTSEIATLAGYEQFAPWLLVEKRGNVHVVSINRPEALNAVTEEVHHAFATIWKVLDADTDVKAVVTTGV GKAFSAGGDMVMFGRLIEDEVARTYQIHEARTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDLLVMGE NSYLADPHVAVGLTAGDGGTAMLPLLIGMMKAKEYVLLGDRITAPIAEKLNLVTKVVSDDTVLDEALALG ERFAALPPQALRSSKVALNMHLARAAQGVLEYALAEELTSFSTPEFKERVAAFLARSKK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1818 | - | - | 100% (269) | enoyl-CoA hydratase |
| M. avium 104 | MAV_2558 | - | e-131 | 87.73% (269) | enoyl-CoA hydratase |
| M. avium 104 | MAV_0867 | - | 7e-52 | 44.17% (240) | enoyl-CoA hydratase/isomerase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2698 | echA15 | 2e-40 | 40.89% (225) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2395 | - | 2e-49 | 40.33% (243) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2679 | echA15 | 2e-40 | 40.89% (225) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 3e-28 | 30.56% (252) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 2e-28 | 31.42% (261) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4790 | - | 1e-53 | 44.90% (245) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5620 | - | 1e-58 | 44.62% (251) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3709 | - | 1e-125 | 84.01% (269) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0359 | - | 1e-53 | 44.49% (245) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4253 | - | 7e-49 | 40.24% (246) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2698|M.bovis_AF2122/97 ----MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHRDLA
Rv2679|M.tuberculosis_H37Rv ----MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHRDLA
MAV_1818|M.avium_104 MTTSEIATLAGYEQFAPWLLVEKRGNVHVVSINRPEALNAVTEEVHHAFA
TH_3709|M.thermoresistible__bu MTTSEIATLPGYEEFAPWLLVEKRGAVHVVSINRPEAFNAVNEEVHHAFA
Mflv_2395|M.gilvum_PYR-GCK -----------MYGMPDEIDVTADGDLRIITLNRPDDLNAVNDNLHVGLA
Mvan_4253|M.vanbaalenii_PYR-1 -----------MYGMPEEIDVRADGALRIITLNRPDDLNAVNDNLHVGLA
MMAR_4790|M.marinum_M -----------MYDMPTEIDVRAEGALRIITLNRPDALNAVNDNLHVGLA
MUL_0359|M.ulcerans_Agy99 -----------MYDMPTEIDVRAEGALRIITLNRPDALNAVNDNLHVGLA
MSMEG_5620|M.smegmatis_MC2_155 ----------MNYDVPDELSVSTDGPVRIVTINRETDLNSVNEKLHWALA
MLBr_02402|M.leprae_Br4923 -------------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEIT
MAB_1185c|M.abscessus_ATCC_199 ----------MTSHNFETILTERIDRVAVITLNRPKALNALNSQVMNEVT
: : : :*:: .: .:
Mb2698|M.bovis_AF2122/97 DIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREA
Rv2679|M.tuberculosis_H37Rv DIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREA
MAV_1818|M.avium_104 TIWKVLDADTDVKAVVTTGVGKAFSAGGDMVMFGRLIEDEVARTYQIHEA
TH_3709|M.thermoresistible__bu TIWRRLTDDEDVRAVVTTGVGKAFSAGGDMVMFGRLIEDPVARQFQITEA
Mflv_2395|M.gilvum_PYR-GCK KIWEELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTIKHG
Mvan_4253|M.vanbaalenii_PYR-1 KIWEELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTIKHG
MMAR_4790|M.marinum_M GLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTIAHG
MUL_0359|M.ulcerans_Agy99 GLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTIAHG
MSMEG_5620|M.smegmatis_MC2_155 NVWRQLAADKDAKVVVLTGAGRAFSAGGDLGWITTFLDDPVARDESIREG
MLBr_02402|M.leprae_Br4923 NAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAW
MAB_1185c|M.abscessus_ATCC_199 TAAAEFDADHGIGAIIITGSEKAFAAGADIKEMSEQSFSDMFGSDFFSAW
: * . : * :.*::*..: : :
Mb2698|M.bovis_AF2122/97 RDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTK
Rv2679|M.tuberculosis_H37Rv RDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTK
MAV_1818|M.avium_104 RTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDLLVMGENSYLADPHVA
TH_3709|M.thermoresistible__bu RTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGRSSYLADPHVA
Mflv_2395|M.gilvum_PYR-GCK RDLVIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVS
Mvan_4253|M.vanbaalenii_PYR-1 RDLVIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVS
MMAR_4790|M.marinum_M RDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQ
MUL_0359|M.ulcerans_Agy99 RDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQ
MSMEG_5620|M.smegmatis_MC2_155 AQIIEEMLRFPLPVIAAVNGPAVGLGCSVALLCDILLISEDAYLADPHVS
MLBr_02402|M.leprae_Br4923 G----KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIK
MAB_1185c|M.abscessus_ATCC_199 G----KLGAVRTPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQPEIK
: * ::*: * *:* * :. :.*. . : : : .
Mb2698|M.bovis_AF2122/97 LGVAAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDD
Rv2679|M.tuberculosis_H37Rv LGVAAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDD
MAV_1818|M.avium_104 VGLTAGDGGTAMLPLLIGMMKAKEYVLLGDRITAPIAEKLNLVTKVVSDD
TH_3709|M.thermoresistible__bu VGLVAGDGGAAMLPLLIGLMKAKQYVLLGDRITPEEAEKLNLVTKVAEDD
Mflv_2395|M.gilvum_PYR-GCK IGLVAADGGPLVWGSQISLLQAKEFALTGVRIKAQKAVELGLANHVVD--
Mvan_4253|M.vanbaalenii_PYR-1 IGLVAADGGPLVWGSQISLLQAKEFALTGVRIKAQRAVELGLANHVVD--
MMAR_4790|M.marinum_M VGLVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVNHVAA--
MUL_0359|M.ulcerans_Agy99 VGLVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLANHVAA--
MSMEG_5620|M.smegmatis_MC2_155 VGLVAGDGGAALWPLLTPIMRSREFLYTGDRIDAGKAVELGLASRSVAPG
MLBr_02402|M.leprae_Br4923 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLAD
MAB_1185c|M.abscessus_ATCC_199 LGVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRVVATE
:*: .. .. : : * . .*.. .
Mb2698|M.bovis_AF2122/97 DVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIG
Rv2679|M.tuberculosis_H37Rv DVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIG
MAV_1818|M.avium_104 TVLDEALALGERFAALPPQALRSSKVALNMHLARAAQGVLEYALAEELTS
TH_3709|M.thermoresistible__bu AVLDDALAIGERLAALPPQALRATKVAMNMHLSRAALGILEYALAEEYTS
Mflv_2395|M.gilvum_PYR-GCK DPVGEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVS
Mvan_4253|M.vanbaalenii_PYR-1 DPVAEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVS
MMAR_4790|M.marinum_M DPVAEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQS
MUL_0359|M.ulcerans_Agy99 DPVAEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQS
MSMEG_5620|M.smegmatis_MC2_155 QLRSEAMTLAHRLAKQPVEALQGTKRVVNMYLSQVLSGPLQAGFAAEQVS
MLBr_02402|M.leprae_Br4923 DLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHST
MAB_1185c|M.abscessus_ATCC_199 SLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLFERRIFHSA
* . : . .* :* :* :
Mb2698|M.bovis_AF2122/97 FGGPDVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv FGGPDVREGLAAHREKRPARFGADPDPGAGS
MAV_1818|M.avium_104 FSTPEFKERVAAFLARSKK------------
TH_3709|M.thermoresistible__bu FTTPEFQERVAAFRAKSNK------------
Mflv_2395|M.gilvum_PYR-GCK FGTADFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1 FGTADFNKIVDGLIAKK--------------
MMAR_4790|M.marinum_M FTTEDFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99 FTTEDFRSIVTRLTAPKN-------------
MSMEG_5620|M.smegmatis_MC2_155 MRSDDHRARLLAFKKKAHK------------
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR-------
MAB_1185c|M.abscessus_ATCC_199 FGTADQSEGMAAFVEKRPANFIHR-------
: : :