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MTLLSEPDFGTPAKPGPATVTVEVDGIPVSVPEGTSVMRAAAEAGIDVPKLCATDRLDAFGSCRLCLVEI DGRRGTPASCTTPVAEGMVVHTQTPKVAKLRESVMELYISDHPLDCLTCPANGDCELQDMAGVVGLRQVR YGYEGANHFDAEPDHSNPYFDFDPSKCIACSRCVRACGEIQGTFALTIEGRGFESKVSPGAGELFMDSEC VSCGACVQACPTATLQERSVVELGIPTRSVTTTCAYCGVGCSFKAELRGDELVRMVPQKAGGANEGHSCV KGRFAFGYATHPDRVLRPMVRDKITDPWREVEWDEAINTVARRMQEIAQRHGAGAIGAITSSRCTNEEVY VVQKMVRAAFGNNNVDTCARVCHSPTGYGLKQTFGESAGTQDFRSVAEADVIVVIGANPTDGHPVFASRM KQRIREGARLVVVDPRRIDLVRSPHIEADHHLQLRPGTNVAVVNAMAHVVVTEGLTDASFVAERCEGFEE WAEFIAREENSPEAVEPITGVPAEELRAAARLYALAPNAAIYYGLGVTEHSQGSTMVMGMANLAMACGNI GRDGVGVNPLRGQNNVQGSCDMGSFPHELPGYRHVSDDAVRQVFENLWGTELLAEPGLRIPNMFDAAIEG SFRGLFVHGEDIAQSDPNVKHVLAALESMELVVVQDLFLNETSKYAHVFLPGASFLEKDGTFTNAERRIN RVRAVMKPKSGMHEWDIVCRIATAMGYPMHYDHPSQIMDEIATLTPTFTGVSFDKLDQLGSIQWPCDEEA PEGTPIMHVDAFTRGLGRFVPTPFVPTDERSTRRFPLILTTGRILSQYNVGAQTRRTANIAWHAEDVLEI HPHDAEVRGIADGDLVTLASRVGETTLHAQTSDRMPTGVVYTTFHYPVTGANVVTTDSSDWATNCPEYKV TAVQVALAPPSARQAEARVDELPETELVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0161 | - | - | 100% (939) | formate dehydrogenase, alpha subunit |
| M. smegmatis MC2 155 | MSMEG_2837 | - | 1e-64 | 28.98% (704) | nitrate reductase NarB |
| M. smegmatis MC2 155 | MSMEG_2057 | nuoG | 1e-52 | 31.89% (439) | NADH dehydrogenase subunit G |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3175 | nuoG | 8e-53 | 32.21% (416) | NADH dehydrogenase subunit G |
| M. gilvum PYR-GCK | Mflv_3016 | - | 1e-82 | 29.62% (736) | molybdopterin oxidoreductase |
| M. tuberculosis H37Rv | Rv3151 | nuoG | 8e-53 | 32.21% (416) | NADH dehydrogenase subunit G |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2438 | - | 6e-85 | 31.86% (703) | oxidoreductase |
| M. marinum M | MMAR_3639 | fdhF | 2e-92 | 31.11% (720) | formate dehydrogenase H FdhF |
| M. avium 104 | MAV_2075 | - | 2e-98 | 32.69% (731) | FdhF protein |
| M. thermoresistible (build 8) | TH_0631 | nuoG | 8e-51 | 30.72% (433) | PROBABLE NADH DEHYDROGENASE I (CHAIN G) NUOG |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 3e-92 | 30.69% (743) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_3491 | - | 6e-82 | 29.59% (747) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3639|M.marinum_M MAPNKDAVKTVCAYCGVGCGIVLQTTTDP-QTGKRRVAKSTGDKSHPANL
MUL_1474|M.ulcerans_Agy99 MAPNKDAVKTVCAYCGVGCGIVLQTTTDP-QTGKRRVAKSTGDKSHPANL
MAV_2075|M.avium_104 -------MNTMCAYCGVGCGMVLQITTDP-QTGRRHVAKSVGNKEHPANF
Mflv_3016|M.gilvum_PYR-GCK ------MTRTACSYCGVGCGISVETRTDP-ASGVPVIARVSGDKLHPTNF
Mvan_3491|M.vanbaalenii_PYR-1 ------MTRTACSYCGVGCGISVETRTDP-ATGVPVIARVTGDKLHPSNF
MAB_2438|M.abscessus_ATCC_1997 ------------------------MRTDAHAAGPVTVATVEGDVLHPSNQ
Mb3175|M.bovis_AF2122/97 ---------------------MTQAADTDIRVGQP--EMVTLTIDGVEIS
Rv3151|M.tuberculosis_H37Rv ---------------------MTQAADTDIRVGQP--EMVTLTIDGVEIS
TH_0631|M.thermoresistible__bu ---------------------MTSSTSSPAGTGRAPVEMVNLTIDGTEIS
MSMEG_0161|M.smegmatis_MC2_155 --------------------MTLLSEPDFGTPAKPGPATVTVEVDGIPVS
.
MMAR_3639|M.marinum_M GRLCTKGTTTADLLAA-PGRMESAHLRAHRAGHLESIPIDDAITQCAMRL
MUL_1474|M.ulcerans_Agy99 GRLCTKGTTTADLLAA-PGRMESAHLRAHRAGHLESIPIDDAITQCAMRL
MAV_2075|M.avium_104 GRLCTKGATTADLLAA-PGRMDSAHARAGRGEPLEPIGTDQAITRCAKQL
Mflv_3016|M.gilvum_PYR-GCK GRLCTKGATHAEMMAATDGRLTTALVRPSRDADPVALDVDDAVAEAGSRL
Mvan_3491|M.vanbaalenii_PYR-1 GRLCTKGATHAEMMAATDGRLTTALLRPSRDAEPVATDVDDALAEAGARL
MAB_2438|M.abscessus_ATCC_1997 GRLCTKGATHAQLMAA-DGRMTTAHLRSIRGQQPIPAPLAAATAEAGRRL
Mb3175|M.bovis_AF2122/97 VPKGTLVIRAAELMGIQIPRFCDHPLLEPVG------ACRQCLVEVEGQR
Rv3151|M.tuberculosis_H37Rv VPKGTLVIRAAELMGIQIPRFCDHPLLEPVG------ACRQCLVEVEGQR
TH_0631|M.thermoresistible__bu VPKGTLVIRAAELLGVEIPRFCDHPLLDPVG------ACRQCLVEIEGQR
MSMEG_0161|M.smegmatis_MC2_155 VPEGTSVMRAAAEAGIDVPKLCATDRLDAFG------SCRLCLVEIDGRR
* * . :: . .. :
MMAR_3639|M.marinum_M RAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTNQIESNSRLCMA
MUL_1474|M.ulcerans_Agy99 RAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMA
MAV_2075|M.avium_104 RAIIDEHGPDAFAMYVSGQMSLEAQYLANKLTKGFIGTNQIESNSRLCMA
Mflv_3016|M.gilvum_PYR-GCK RAIVDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRLCMA
Mvan_3491|M.vanbaalenii_PYR-1 RAILDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRLCMA
MAB_2438|M.abscessus_ATCC_1997 REILDNHGPDAIALYVSGQMTLEAQYLANKLAKGYIRTTHIESNSRLCMA
Mb3175|M.bovis_AF2122/97 KPLASCTTVATDDMVVRTQLTSEIADKAQHGVMELLLINHP-LDCPMCDK
Rv3151|M.tuberculosis_H37Rv KPLASCTTVATDDMVVRTQLTSEIADKAQHGVMELLLINHP-LDCPMCDK
TH_0631|M.thermoresistible__bu KPMASCTTTVMPDMVVRTQLTSEAAAAAQHGVMELLLINHP-LDCPVCDK
MSMEG_0161|M.smegmatis_MC2_155 GTPASCTTPVAEGMVVHTQTPKVAKLRES--VMELYISDHP-LDCLTCPA
. : * * . . : :. *
MMAR_3639|M.marinum_M GASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERV
MUL_1474|M.ulcerans_Agy99 GASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERV
MAV_2075|M.avium_104 SAGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCHPILFLRMMDRV
Mflv_3016|M.gilvum_PYR-GCK SAGTGYKQSLGSDGPPGSYTDFDCTNLFFVIGSNMADCHPILYLRMADRL
Mvan_3491|M.vanbaalenii_PYR-1 SAGTGFKQSLGADGPPGSYTDFDCTDLFFVIGSNMADCHPILYLRMADRL
MAB_2438|M.abscessus_ATCC_1997 SAGTGYAQSLGADGPPGSYSDIEHSDLFFVIGANMADCHPILFLRMADRL
Mb3175|M.bovis_AF2122/97 GGECPLQNQAMSNGR--------------------TDSRFTEAKRTFAKP
Rv3151|M.tuberculosis_H37Rv GGECPLQNQAMSNGR--------------------TDSRFTEAKRTFAKP
TH_0631|M.thermoresistible__bu GGECPLQNQAMSTGR--------------------AETRFEDVKRTFPKP
MSMEG_0161|M.smegmatis_MC2_155 NGDCELQDMAGVVGLR------------------QVRYGYEGANHFDAEP
.. * . : .
MMAR_3639|M.marinum_M KSGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDP
MUL_1474|M.ulcerans_Agy99 KSGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDP
MAV_2075|M.avium_104 KAGAKLIVVDPRRTATAEKADLFLQIAPGTDLALLNGLLHLIVENGHTDG
Mflv_3016|M.gilvum_PYR-GCK KAGARLIVVDPRRTATADKADLYLPIRPGTDLALLNGILRVLVQDGAIDE
Mvan_3491|M.vanbaalenii_PYR-1 KAGAKLIVVDPRRTATADKADLYLPIRPGTDLALLNGILHLLVENGAVDQ
MAB_2438|M.abscessus_ATCC_1997 SSGARLIVVDPRRTATADRADLFLQITPGTDLALLNGLLHLLVENGAVDA
Mb3175|M.bovis_AF2122/97 INISAQVLLDRERCILCARCTRFSDQIAGDPFIDMQERGALQQVGIYADE
Rv3151|M.tuberculosis_H37Rv INISAQVLLDRERCILCARCTRFSDQIAGDPFIDMQERGALQQVGIYADE
TH_0631|M.thermoresistible__bu INISSQVLLDRERCVLCARCTRFSQQIAGDPFIELLERGALQQVGIAPEQ
MSMEG_0161|M.smegmatis_MC2_155 DHSNPYFDFDPSKCIACSRCVRACGEIQGTFALTIEGRGFESKVSPGAGE
. .* : . :. * : .
MMAR_3639|M.marinum_M QFISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWM
MUL_1474|M.ulcerans_Agy99 QFISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWM
MAV_2075|M.avium_104 EFIAEFTEGWEVMPSFLEQYTPDRVSEITGIPEQDIRAAAQLIGEADNFM
Mflv_3016|M.gilvum_PYR-GCK AFIAEHTEGWEAMPAFLADYPPSRVAEITGLAEADIRSAAAMIAEAGDWI
Mvan_3491|M.vanbaalenii_PYR-1 EFIAEHTQGWESMPEFLAGYPPDRVAAITGLSEADIRAAADMIAEAGDWL
MAB_2438|M.abscessus_ATCC_1997 EFIAQHTEGWDGMPEFLAGYAPAVVAAITGLAEEDIRTAARWIGEAREWM
Mb3175|M.bovis_AF2122/97 PFESYFSG------------------------------------------
Rv3151|M.tuberculosis_H37Rv PFESYFSG------------------------------------------
TH_0631|M.thermoresistible__bu PFQSYFSG------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 LFMDSECVSCG---------------------------------------
*
MMAR_3639|M.marinum_M SCWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGR
MUL_1474|M.ulcerans_Agy99 SCWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGR
MAV_2075|M.avium_104 SCWTMGLNQSTHGTWNTNAICNLHLATGAICKPGSGPFSLTGQPNAMGGR
Mflv_3016|M.gilvum_PYR-GCK SCWTMGLNQSTHGTWNTNAICNLHLATGAICRPGAGPMSLTGQPNAMGGR
Mvan_3491|M.vanbaalenii_PYR-1 SCWTMGLNQSTHGTWNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGR
MAB_2438|M.abscessus_ATCC_1997 TLWTMGLNQSTHGTWNTNAICNLHLATGAICRPGSGPFSLTGQPNAMGGR
Mb3175|M.bovis_AF2122/97 ---------------NTVQICPVGALTGTAYRFRARPFDLVSSPSVCEHC
Rv3151|M.tuberculosis_H37Rv ---------------NTVQICPVGALTGTAYRFRARPFDLVSSPSVCEHC
TH_0631|M.thermoresistible__bu ---------------NTVQICPVGALTGAAYRFRARPFDLVSSPTVCEHC
MSMEG_0161|M.smegmatis_MC2_155 ---------------ACVQACPTATLQERSVVELG--IPTRSVTTTCAYC
* . : . ...
MMAR_3639|M.marinum_M EMGYMGPGLPGQRSVLS--APDREFVEEQWGLPGGALRTDVSGGVIDMFS
MUL_1474|M.ulcerans_Agy99 EMGYMGPGLPGQRSVLS--APDREFVEEQWGLPGGALRTDVSGGVIDMFS
MAV_2075|M.avium_104 EMGYMGPGLPGQRSVAS--AADREFVEDVWGVPRGRLRTEVGTGTIDMFS
Mflv_3016|M.gilvum_PYR-GCK EMGYMGPGLPGQRAVLS--AEDRSFVETQWDLEPGTVRTEVGPGTVEMFR
Mvan_3491|M.vanbaalenii_PYR-1 EMGYMGPGLPGQRSVAS--AADRAFVEEQWDLEPGTIRADIGPGTVEMFR
MAB_2438|M.abscessus_ATCC_1997 EMGYMGPGLPGQRSVKS--PADRDFVEKRWQLPPGSIRAEFGTGTVDMFA
Mb3175|M.bovis_AF2122/97 ASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKG---------------
Rv3151|M.tuberculosis_H37Rv ASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKG---------------
TH_0631|M.thermoresistible__bu ASGCAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKG---------------
MSMEG_0161|M.smegmatis_MC2_155 GVGCSFKAELRGDELVRMVPQKAGGANEGHSCVKG---------------
* : . . .: *
MMAR_3639|M.marinum_M RMADGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNE
MUL_1474|M.ulcerans_Agy99 RMADGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNE
MAV_2075|M.avium_104 RMADGQIKACWIICTNPVASVANRKTVLAGLERAELVIAQDAYLGTETSE
Mflv_3016|M.gilvum_PYR-GCK RIAGGDIKAVWIICTNPVASVANRDTVITGLQSAELVITQDAYVDTATNR
Mvan_3491|M.vanbaalenii_PYR-1 QMGSGDIKAAWIICTNPVASVANRDAVVAGLSTAELVITQDVYADTATNR
MAB_2438|M.abscessus_ATCC_1997 QMAAGNIKACWIICTNPVASVANRKNVVDGLRRAELVIAQDAFLATATNE
Mb3175|M.bovis_AF2122/97 ---------RWAFTYATQPDVITTPLIRDGGD--------------PKGA
Rv3151|M.tuberculosis_H37Rv ---------RWAFTYATQPDVITTPLIRDGGD--------------PKGA
TH_0631|M.thermoresistible__bu ---------RWAFTYTRVGDRLTAPLVRG-----------------ADGE
MSMEG_0161|M.smegmatis_MC2_155 ---------RFAFGYATHPDRVLRPMVRDKIT----------------DP
: : : .
MMAR_3639|M.marinum_M YANVLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIAC
MUL_1474|M.ulcerans_Agy99 YANVLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIAC
MAV_2075|M.avium_104 YADVLLPAALWAETEGVMVNSERNITLSQPAVAAPGGAMPDWQIIARIAC
Mflv_3016|M.gilvum_PYR-GCK YADIMLPATLWAEADAVMVNSGRTLTLLAQSVPAAGDARPDWELICGVAR
Mvan_3491|M.vanbaalenii_PYR-1 YADIVLPATLWAETDAVMVNSDRNLTLLQQSVPPVGDARPDWELICGVAR
MAB_2438|M.abscessus_ATCC_1997 YADILLPAALWAESDGVSINSERTATLTNRAVEAPGDARPDWQLICDIAT
Mb3175|M.bovis_AF2122/97 LVPTSWSHAMAVAAQGLAAARGRTGVLVGGRVT-----WEDAYAYAKFAR
Rv3151|M.tuberculosis_H37Rv LVPTSWSHAMAVAAQGLAAARGRTGVLVGGRVT-----WEDAYAYAKFAR
TH_0631|M.thermoresistible__bu LRSASWPEALYTAARGLAGAVGRAGVLVGGRAT-----VTDAYSYAKFAR
MSMEG_0161|M.smegmatis_MC2_155 WREVEWDEAINTVARRMQEIAQRHGAGAIGAITSSRCTNEEVYVVQKMVR
:: . : : * : ..
MMAR_3639|M.marinum_M EMGFSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCP
MUL_1474|M.ulcerans_Agy99 EMGFSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCP
MAV_2075|M.avium_104 EMGFSEAFSYSCAEEVFEEIKRFWNPTTGYDLRGVSYERLRRQPLQWPCP
Mflv_3016|M.gilvum_PYR-GCK HLGFGDAFDHKSSEEIFDEIRRFHNPRTGYDLRGVTYERLRATPVQWPCP
Mvan_3491|M.vanbaalenii_PYR-1 HLGFGDAFDYKSSEQIFDEIRRFHNPGTGYDLRGITYERLRDTPVQWPCA
MAB_2438|M.abscessus_ATCC_1997 AMGFGDAFGYSSSEEIFEEIRAFWNPRTGYDMRGMSYARLRQGPVQWPCP
Mb3175|M.bovis_AF2122/97 ITLGTNDIDFRARPHSAEEADFLAARIAGRHMA-VSYADLESAPVVLLVG
Rv3151|M.tuberculosis_H37Rv ITLGTNDIDFRARPHSAEEADFLAARIAGRHMA-VSYADLESAPVVLLVG
TH_0631|M.thermoresistible__bu MVLGGNDIDFRARTHSAEEADFLAAVVAGRPMP-VTYTDLERAPAVLLAG
MSMEG_0161|M.smegmatis_MC2_155 AAFGNNNVDTCAR-VCHSPTGYGLKQTFGESAGTQDFRSVAEADVIVVIG
: .. . . * . :
MMAR_3639|M.marinum_M PDGASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLV
MUL_1474|M.ulcerans_Agy99 PDGASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLV
MAV_2075|M.avium_104 PQSTADRNPIRYLNDGVSQTQLVREDGTVPRLAFPTPSGRAVFFARPHLQ
Mflv_3016|M.gilvum_PYR-GCK SEDAPDRNPIRYLNDGVSQDLHIDDDGHIPRLAFATPSRRAVFHPRPHLD
Mvan_3491|M.vanbaalenii_PYR-1 SAEQSDRNPIRYLNDGVSQDQYVGPDGHRPRLAFPTPSRRAVFHPRPHMD
MAB_2438|M.abscessus_ATCC_1997 PESEVDRNPIRYLNDGISQHPHVDENGVVPRLAFPTPSRRAVFHARAHRD
Mb3175|M.bovis_AF2122/97 FEPE-DESPIVFLRLRKAARRHRVPVYTIAPFATGG--------------
Rv3151|M.tuberculosis_H37Rv FEPE-DESPIVFLRLRKAARRHRVPVYTIAPFATGG--------------
TH_0631|M.thermoresistible__bu FEPE-EESPIVFLRLRKAVRKHGLRVMSVAPYASPG--------------
MSMEG_0161|M.smegmatis_MC2_155 ANPTDGHPVFASRMKQRIREGARLVVVDPRRIDLVR--------------
. :
MMAR_3639|M.marinum_M PDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDA
MUL_1474|M.ulcerans_Agy99 PDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDA
MAV_2075|M.avium_104 PEEMPDDDYPFLLNTGRLPHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDA
Mflv_3016|M.gilvum_PYR-GCK AAELPDDDYPFILNTGRLQHQWHTMTKTGRVAKLTKLNPAPFVEIHPSDA
Mvan_3491|M.vanbaalenii_PYR-1 AAELPDDDYPLVLNTGRLQHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDA
MAB_2438|M.abscessus_ATCC_1997 PAELPGEGYPVVLNTGRLQHHWHTLTKTGRIKTLDRLHPSPFVEIHPHDA
Mb3175|M.bovis_AF2122/97 --------------LHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPG
Rv3151|M.tuberculosis_H37Rv --------------LHKMSGRLIKTVPGGEPAALDDLATGAVGDLLATPG
TH_0631|M.thermoresistible__bu --------------LTKLGGRLLPTVPGGEAEALDALHD---DDWLTRPG
MSMEG_0161|M.smegmatis_MC2_155 -------------SPHIEADHHLQLRPGTNVAVVNAMAHVVVTEGLTDAS
: . : : : . .
MMAR_3639|M.marinum_M ADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLS
MUL_1474|M.ulcerans_Agy99 ADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLS
MAV_2075|M.avium_104 ARLGIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFHWNDAFGEYLS
Mflv_3016|M.gilvum_PYR-GCK AALGITDGQDLELRTRRGRAVLPAVLTERVRPGNTWAPFHWNDEHGENLT
Mvan_3491|M.vanbaalenii_PYR-1 AALGISGGHDVELVTRRGRAVLPAVLTDRVQPGNTWVPFHWNDEHGDHLT
MAB_2438|M.abscessus_ATCC_1997 TTLGISDGDIVEIASRRGTAELPALVSDRVKRGSCFAPFHWNDAHGPGLT
Mb3175|M.bovis_AF2122/97 AVIMVGER----LATVPGGLSAAARLADTTGARLAWVPRRAGERGALEAG
Rv3151|M.tuberculosis_H37Rv AVIIVGER----LATVPGGLSAAARLADTTGARLAWVPRRAGERGALEAG
TH_0631|M.thermoresistible__bu AVILTGER----LAGHPGAYSAAARLADATGARLAWIPRRAGEX---XXN
MSMEG_0161|M.smegmatis_MC2_155 FVAERCEG----FEEWAEFIAREENSPEAVEPITGVPAEELRAAARLYAL
: .: . . .
MMAR_3639|M.marinum_M INAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADTCADATAP
MUL_1474|M.ulcerans_Agy99 INAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACADATAP
MAV_2075|M.avium_104 INAVTNDAVDPISNQPEFKACAVTLTKVAVSHPDSAIG-TGPSAGHDTPE
Mflv_3016|M.gilvum_PYR-GCK INALTNDAVDPDSLQPEFKVCAVRLTPVPAADG-----------------
Mvan_3491|M.vanbaalenii_PYR-1 VNALTNDAVDPDSLQPEFKVCAVRLAPVPAAG------------------
MAB_2438|M.abscessus_ATCC_1997 INAVTNDAVDPDSLQPEFKVSAVALRPT----------------------
Mb3175|M.bovis_AF2122/97 ALPTLLPGGRPLADEVARAQVCAAWHIAELPAAA----------------
Rv3151|M.tuberculosis_H37Rv ALPTLLPGGRPLADEVARAQVCAAWHIAELPAAA----------------
TH_0631|M.thermoresistible__bu ASPTG---------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 APNAAIYYGLGVTEHSQGSTMVMGMANLAMACGN----------------
MMAR_3639|M.marinum_M KLLADTAQFSVTQVDALAELLGVANEPTPQFGPFARSYLAGLIAGLRSET
MUL_1474|M.ulcerans_Agy99 KLLADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSET
MAV_2075|M.avium_104 SAPTEVREISVSQVDALGELLGVATSFKPEFNELGRSYLAGMLTGLRSDV
Mflv_3016|M.gilvum_PYR-GCK ---------------------------APDLTDDEKLYIAGFLAGVDEGR
Mvan_3491|M.vanbaalenii_PYR-1 ---------------------------APEFTETEKLYLAGFFAGIEEGL
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3175|M.bovis_AF2122/97 --------------------------------------------------
Rv3151|M.tuberculosis_H37Rv --------------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M GRRMAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAA
MUL_1474|M.ulcerans_Agy99 GRRMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAA
MAV_2075|M.avium_104 GRRAGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADASQQAALPEPPQPA
Mflv_3016|M.gilvum_PYR-GCK ----PGVPVLPAGAPVGARARLWVDGLLAGRYSRLETAAPS---------
Mvan_3491|M.vanbaalenii_PYR-1 ----PGVPVLPASAPVGPRARLWVDGLLAGRYSRSDTVAET---------
MAB_2438|M.abscessus_ATCC_1997 -----------------------------GRTKADSMPEKQ---------
Mb3175|M.bovis_AF2122/97 --------------------------------------------------
Rv3151|M.tuberculosis_H37Rv --------------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M AQSDNAAEA----AVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVV
MUL_1474|M.ulcerans_Agy99 AQSDNAAEA----AVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVV
MAV_2075|M.avium_104 AQQPPAAPAGATPAPERAPVVVLWASQTGNAEELAADVAAQLAAAELPVA
Mflv_3016|M.gilvum_PYR-GCK -------------ASPRGGPLVLWASQTGTAEEFAGSLGERLA----GAR
Mvan_3491|M.vanbaalenii_PYR-1 -------------PATEG-PLVLWASQTGNAEEFAGRLGERLN----GAR
MAB_2438|M.abscessus_ATCC_1997 -------------KEALGDVAILWTSQTGNAETAAVSVHRLLHTAGISAT
Mb3175|M.bovis_AF2122/97 -------------GRDADGILAAAADETLAALLVGGIEPADFADPDAVLA
Rv3151|M.tuberculosis_H37Rv -------------GRDADGILAAAADETLAALLVGGIEPADFADPDAVLA
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 ----------------------------------IGRDGVGVNPLRGQNN
MMAR_3639|M.marinum_M LHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAATAPSLA
MUL_1474|M.ulcerans_Agy99 LHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLA
MAV_2075|M.avium_104 LHSMDDFPAAELAATRELLLITSTTGDGDAPDNGSGLWRALTGDAAPRLG
Mflv_3016|M.gilvum_PYR-GCK LRAMDDTDLSELSDAGEVVIVTSTFGDGGPPDNGTAFWERLESADAPALD
Mvan_3491|M.vanbaalenii_PYR-1 LRAMDDVELDDLSEAGEVVIVTSTFGDGGPPDNGAGFWERLESPHAPSLD
MAB_2438|M.abscessus_ATCC_1997 ITAMDECDPADLVGVNTAVVIASSFGEGGPPDNGARFWAALSGDTKP-LN
Mb3175|M.bovis_AF2122/97 ALDATGFVVSLELRHSAVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEP
Rv3151|M.tuberculosis_H37Rv ALDATGFVVSLELRHSTVTERADVVFPVAPTTQKAGAFVNWEGRYRTFEP
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 VQGSCDMGSFPHELPGYRHVSDDAVRQVFENLWGTELLAEPGLRIPNMFD
MMAR_3639|M.marinum_M GTRYSVLALGDSNYADFCGHGRALDHRLAELGASRVTDRVDCEPDYEESA
MUL_1474|M.ulcerans_Agy99 GTRYSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEESA
MAV_2075|M.avium_104 NTRYAVLALGDSNYDDFCGHGRKLDARLAELGATRIAERVDCEPDYEQAA
Mflv_3016|M.gilvum_PYR-GCK GVRYTVLGIGDRSYDNFCGHAKSLDTRLADLGATRMLDRADCEAYDEQPM
Mvan_3491|M.vanbaalenii_PYR-1 GVRYTVLGIGDRSYDNFCGHARSLDARLADLGATRMLDRVECEAYDAQPL
MAB_2438|M.abscessus_ATCC_1997 HMRYAVLGFGDRAYADFCGHAKALDARLHELGASPLLGRVDGEATDRTLV
Mb3175|M.bovis_AF2122/97 ALRGSTLQAGQSDHRVLDALADDMGVHLGVPTVEAAREELAALGIWDGKH
Rv3151|M.tuberculosis_H37Rv ALRGSTLQAGQSDHRVLDALADDMGVHLGVPTVEAAREELAALGIWDGKH
TH_0631|M.thermoresistible__bu --------------------------------VSTATRSITKSTVWWSKS
MSMEG_0161|M.smegmatis_MC2_155 AAIEGSFRGLFVHGEDIAQSDPNVKHVLAALESMELVVVQDLFLNETSKY
MMAR_3639|M.marinum_M ARWLQEVLDGLRRTAPPV---------ITAAPVRAASIANR--PQGYTKK
MUL_1474|M.ulcerans_Agy99 ARWLQEVLDGLRRTAPPV---------ITAEPVRAASIASR--PQGYTKK
MAV_2075|M.avium_104 AKWVADVIEALTRTPTAVGGDGGATVSARTSPVAAPSRPNTPAPHTYSKK
Mflv_3016|M.gilvum_PYR-GCK AAWADSVVGLMSTPVTPAP---------T-------QPAVPAAPAPFTRG
Mvan_3491|M.vanbaalenii_PYR-1 ARWADSVVELVAAPGTPP-------------------AAPAQEPTLFTRA
MAB_2438|M.abscessus_ATCC_1997 ASWTADLLDAIGDGATAIV---------ETVRKLRSEGLRVAAPERFTRD
Mb3175|M.bovis_AF2122/97 AAGPHIAATGPTQPEAGEA---------------------------ILTG
Rv3151|M.tuberculosis_H37Rv AAGPHIAATGPTQPEAGEA---------------------------ILTG
TH_0631|M.thermoresistible__bu TRWRCSGGSAPPR-------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 AHVFLPGASFLEKDGTFTN-------------------------------
:
MMAR_3639|M.marinum_M RPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAH
MUL_1474|M.ulcerans_Agy99 RPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAH
MAV_2075|M.avium_104 HPLITDMVRNTTLNGPKSTKDVRHLVFNLPEDAVSYEAGDALGVWPRNSD
Mflv_3016|M.gilvum_PYR-GCK NPAQAPLCRNVRLTPDGAGKDVRQFGFDISGQDLAYSVGDSLGVWVVNSD
Mvan_3491|M.vanbaalenii_PYR-1 EPVAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYSVGDSLGVCVVNSD
MAB_2438|M.abscessus_ATCC_1997 APILAALSHNELLSAPNSGKEVRRIEFDLTGHDVSYSAGDALGIYPTNRE
Mb3175|M.bovis_AF2122/97 WRMLLDEGRLQDGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSR
Rv3151|M.tuberculosis_H37Rv WRMLLDEGRLQDGEPYLAGTARTPVVRLSPDTAAEIGAADGEAVTVSTSR
TH_0631|M.thermoresistible__bu -------GRRAGRSP--TSTRRRRRRPDCSTSGSTWAAPDGSRRSPTWSR
MSMEG_0161|M.smegmatis_MC2_155 --AERRINRVRAVMKPKSGMHEWDIVCRIAT-AMGYPMHYDHPSQIMDEI
: : .
MMAR_3639|M.marinum_M QLVDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVA
MUL_1474|M.ulcerans_Agy99 QLVDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVA
MAV_2075|M.avium_104 ELVDEWLAVTGLDGQTPVEVGEHGLMSLRSALTERIEIAHISRDLVRFVQ
Mflv_3016|M.gilvum_PYR-GCK AVVESWLSATGFHGAEAVIVDGR-QISLREALTRHYDVCKVTSNLVTFVA
Mvan_3491|M.vanbaalenii_PYR-1 FVVENWLAATDLRGDEAVVVDGV-QQALRDALTAHYDVCKVTSNLVKFVA
MAB_2438|M.abscessus_ATCC_1997 EDVQRWLTTTGFDAQLPVTIDGG-ELPLATALANHYDICRVTEDLLRFIA
Mb3175|M.bovis_AF2122/97 GSITLPCSVTDMP-------DRVVWLPLNSAGSTVHRQLRVTIGSIVKIG
Rv3151|M.tuberculosis_H37Rv GSITLPCSVTDMP-------DRVVWLPLNSAGSTVHRQLRVTIGSIVKIG
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 ATLTPTFTGVSFDKLDQLGSIQWPCDEEAPEGTPIMHVDAFTRGLGRFVP
MMAR_3639|M.marinum_M QRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWM
MUL_1474|M.ulcerans_Agy99 QRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWM
MAV_2075|M.avium_104 ERTGDA----KLAELLKPENKRALADWTWGRQSIDLLAQLPVSASAHEWL
Mflv_3016|M.gilvum_PYR-GCK EHCPDA----ATAKRLRN-DRGALDTWLVDRNGLDLVREFGIRADPALWQ
Mvan_3491|M.vanbaalenii_PYR-1 EHCRDA----ATAKRLRN-DRGELDRWLVNRNGLDLVREFSVRADPQLWQ
MAB_2438|M.abscessus_ATCC_1997 ERRRDK----HSAKLLQGRDTQAREVWLRGRNALDVIREFPIRAAIEEWQ
Mb3175|M.bovis_AF2122/97 AGS-----------------------------------------------
Rv3151|M.tuberculosis_H37Rv AGS-----------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 TP----------------------------------FVPTDERSTRRFPL
MMAR_3639|M.marinum_M SVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLA
MUL_1474|M.ulcerans_Agy99 SVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLA
MAV_2075|M.avium_104 RVLKRLQPRLYSISSSPKACPGEVHLTVSPVRYN-FQGVPRRGVCSTYLA
Mflv_3016|M.gilvum_PYR-GCK EVLVRLTPRQYSISSSPLVSPHEVQLTVSVVRYRGADGTPRGGVASTYLA
Mvan_3491|M.vanbaalenii_PYR-1 EVLVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGADGGPRGGVASTYLA
MAB_2438|M.abscessus_ATCC_1997 QVLIRLTPRQYSISSSPLVSPQAISLTVSIVRYQGPDGSPRGGVGSTFLA
Mb3175|M.bovis_AF2122/97 --------------------------------------------------
Rv3151|M.tuberculosis_H37Rv --------------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 ILTTGRILSQYNVGAQTRRTANIAWHAEDVLEIHPHDAEVRG--------
MMAR_3639|M.marinum_M DRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRAL
MUL_1474|M.ulcerans_Agy99 DRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRAL
MAV_2075|M.avium_104 ARSPGDRVAVYLQPSSNFRPPSDPDTPMIMIGPGTGIAPFRGFLQERRAL
Mflv_3016|M.gilvum_PYR-GCK DLPDCTPVPVFLQRSPHFRPPEDPHTPMIMVGPGTGIAPFRGFLQERRAL
Mvan_3491|M.vanbaalenii_PYR-1 DLPDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGIAPFRGFLQERRAL
MAB_2438|M.abscessus_ATCC_1997 DRAQHLPVPIFLQRSPHFRPPRTSDTPMIMIGPGTGIAPFRGFLQERRAL
Mb3175|M.bovis_AF2122/97 --------------------------------------------------
Rv3151|M.tuberculosis_H37Rv --------------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3639|M.marinum_M GHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVY
MUL_1474|M.ulcerans_Agy99 GHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVY
MAV_2075|M.avium_104 GHRGPNWLFFGEQHAATDFYYRDELEQMREDGFLTELDLAFSRDQQHKVY
Mflv_3016|M.gilvum_PYR-GCK GHRGANWLFFGDQHREQNFYYRDDLLDMVDDGFLNRLDLAFSRDQRQRIY
Mvan_3491|M.vanbaalenii_PYR-1 GHRGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRLDLAFSRDQARRVY
MAB_2438|M.abscessus_ATCC_1997 GHTGANWLFFGDQHRTEHFYYRDELDGFLRDGSLRRLDLAFSRDQAKRIY
Mb3175|M.bovis_AF2122/97 --------------------------------------------------
Rv3151|M.tuberculosis_H37Rv --------------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 ----------------------------IADGDLVTLASRVGETTLHAQT
MMAR_3639|M.marinum_M VQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLD
MUL_1474|M.ulcerans_Agy99 VQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLD
MAV_2075|M.avium_104 VQHLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDRALCDIAAEFGNLD
Mflv_3016|M.gilvum_PYR-GCK VQHKMLDYGADVWRWLDDGAHFYVCGDATRMAKDVDDALTEILRTHARMS
Mvan_3491|M.vanbaalenii_PYR-1 VQHKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDDALTEIIRTHGGMS
MAB_2438|M.abscessus_ATCC_1997 VQHRMMEQGAQLWRWLNEGAHLYVCGDASRMAKDVDGALLTIAQKHGKLS
Mb3175|M.bovis_AF2122/97 --------------------------------------------------
Rv3151|M.tuberculosis_H37Rv --------------------------------------------------
TH_0631|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 SDRMPTGVVYTTFHYPVTGANVVTTDSSDWATNCPEYKVTAVQVALAPPS
MMAR_3639|M.marinum_M PESATAFVHALSADKRYHRDVY
MUL_1474|M.ulcerans_Agy99 PESATAFVHALSADKRYHRDVY
MAV_2075|M.avium_104 PDAAKAYVQSLSADKRYHRDVY
Mflv_3016|M.gilvum_PYR-GCK SDAAREYKREMVAEKRYVRDVY
Mvan_3491|M.vanbaalenii_PYR-1 ADAARDYKREMVAEKRYVRDVY
MAB_2438|M.abscessus_ATCC_1997 GEQALEFRKELVAEKRYVRDVY
Mb3175|M.bovis_AF2122/97 ----------------------
Rv3151|M.tuberculosis_H37Rv ----------------------
TH_0631|M.thermoresistible__bu ----------------------
MSMEG_0161|M.smegmatis_MC2_155 ARQAEARVDELPETELVR----