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SPPIPRLRRAMRDEVRDALLAMLMDGRLAAGTSVSIDRLSRDLGVSQTPVREALVEIEATGLVHRVAHRG YQVAPPMTAQQAAELADARLVVETTAAHWATRLRDPELLPDLRAAHRAHEEAAWAVREWDGVTRDRNGLP VPLKPYFEADWRFHQTILDHCGNGFLRRMVGSLGASVQRMRQNVHRGPVDTELAVAEHGRVLAAVETGDP QAAADAMRAHIEAVRERSIADA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2546 | - | - | 100% (233) | GntR family transcriptional regulator protein |
| M. smegmatis MC2 155 | MSMEG_6789 | - | 2e-34 | 39.56% (225) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0535 | - | 2e-12 | 27.59% (203) | GntR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 4e-11 | 43.06% (72) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0958 | - | 1e-14 | 29.87% (231) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 4e-11 | 43.06% (72) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1705c | - | 2e-13 | 27.49% (211) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4029 | - | 1e-11 | 27.44% (215) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1576 | - | 3e-12 | 26.99% (226) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3342 | - | 3e-12 | 28.89% (225) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3894 | - | 3e-12 | 27.44% (215) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5910 | - | 8e-11 | 25.41% (244) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_4029|M.marinum_M ----------------------------------------MTDPEFAARP
MUL_3894|M.ulcerans_Agy99 ----------------------------------------MTDPEFAARP
MAV_1576|M.avium_104 ----------------------------------------MSVPDFAARP
TH_3342|M.thermoresistible__bu ----------------------------------------VAVPEFAARP
MAB_1705c|M.abscessus_ATCC_199 -------------------------------------MPVPPSEGIAARS
MSMEG_2546|M.smegmatis_MC2_155 --------------------------------------MSPPIPRLRR--
Mflv_0958|M.gilvum_PYR-GCK --------------------------------------MADAQLQLAALP
Mvan_5910|M.vanbaalenii_PYR-1 -------------------------------------MLDRPNP------
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MMAR_4029|M.marinum_M ---------QLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99 ---------QLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MAV_1576|M.avium_104 ---------QLSDDVAHLIRGRIFDGSYAAGSYVRLDQLAAELGISVTPV
TH_3342|M.thermoresistible__bu ---------QLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVTPV
MAB_1705c|M.abscessus_ATCC_199 ---------LLRDNAYKALRTAIVDGTLAPGERLRDDELSRWLGVSRTPI
MSMEG_2546|M.smegmatis_MC2_155 ---------AMRDEVRDALLAMLMDGRLAAGTSVSIDRLSRDLGVSQTPV
Mflv_0958|M.gilvum_PYR-GCK AAE-----GRRAEQVMAAVRAALDAGVMRPGVKYSVYQLADALQVSRTPV
Mvan_5910|M.vanbaalenii_PYR-1 --------GALHGSLLTALGTGIVSGQYPPGHVLTLEAVSTEHGVSRSVA
. : : * .* : :* :
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLP-------------------LTRQDI
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLP-------------------LTRQDI
MMAR_4029|M.marinum_M REALFALRAEGLVAQQPHRGFVVLP-------------------LTKRDL
MUL_3894|M.ulcerans_Agy99 REALFALRAEGLVAQQPHRGFVVLP-------------------LTKRDL
MAV_1576|M.avium_104 REALFALRAEGLISQQPRRGFVVLP-------------------VTRRDV
TH_3342|M.thermoresistible__bu REALFQLRAEGLLVQQPRRGFMVLP-------------------VTERDL
MAB_1705c|M.abscessus_ATCC_199 REALARLEQAGLVQTQPGRHTIVSP-------------------IDVREA
MSMEG_2546|M.smegmatis_MC2_155 REALVEIEATGLVHRVAHRGYQVAPP------------------MTAQQA
Mflv_0958|M.gilvum_PYR-GCK RDALLRLEEIGLIRFEARQGFRILL-------------------PDPREI
Mvan_5910|M.vanbaalenii_PYR-1 REAVRVLESMGMLESRRRVGITVQPAESWNVFDPVVIRWRLEVGDRTAQL
*:*: :. *:: : :
Mb0170c|M.bovis_AF2122/97 DDIFWLQATIAQELATSATAHITDVEIDELDRIN-NALAGAIGSGDAKTI
Rv0165c|M.tuberculosis_H37Rv DDIFWLQATIAQELATSATAHITDVEIDELDRIN-NALAGAIGSGDAKTI
MMAR_4029|M.marinum_M ADVAYVQAHVGGELAARAAINIGAAQLAELQQIQ-AQLEEAYAADDDERT
MUL_3894|M.ulcerans_Agy99 ADVAYVQAHVGGELAARAAINIGAAQLAELQQIQ-AQLEEAYAADDDERT
MAV_1576|M.avium_104 TDVANVQAHVGGELAARAAVNITDDQLRELKQIQ-AQLEDAYAGDEHERT
TH_3342|M.thermoresistible__bu TDIANVQAHVGGELAARAAQNITDEQLRVLTAIQ-DELEEAYTRDDEDRA
MAB_1705c|M.abscessus_ATCC_199 RAAQSVAAAMHELAVREAITNISPGDLAAMRHAN-TRFAAALDAHDPDAA
MSMEG_2546|M.smegmatis_MC2_155 AELADARLVVETTAAHWATRLRDPELLPDLRAAHRAHEEAAWAVREWDGV
Mflv_0958|M.gilvum_PYR-GCK ADIVAIRFALEPPAAGRAAAVCGPPLADRLAERMELLRRAAARGDEPGFA
Mvan_5910|M.vanbaalenii_PYR-1 VSLSELRLGFEPAAAALAARRASPHQCRIMATAVSDMVVHGRTGDLDAYL
. . * : .
Mb0170c|M.bovis_AF2122/97 AS--------------IEFAFHRVFNKASRRIKLAWFLLNAAR-YMP-AQ
Rv0165c|M.tuberculosis_H37Rv AS--------------IEFAFHRVFNKASRRIKLAWFLLNAAR-YMG-AG
MMAR_4029|M.marinum_M VR--------------LNHEFHRAINLAADSPRLSQLMSQITR-YQP-ES
MUL_3894|M.ulcerans_Agy99 VR--------------LNHEFHRAINLAADSPRLSQLMSQITR-YQP-ES
MAV_1576|M.avium_104 VR--------------LNHEFHRAINIAADSPKLAQLMSQITR-YAP-ES
TH_3342|M.thermoresistible__bu VR--------------LNHEFHRAINVAADSPKLAQVMSQITR-YAP-ES
MAB_1705c|M.abscessus_ATCC_199 LA--------------ADDEFHAVAVEASANPYIAAVLEQVTP-VLRRLE
MSMEG_2546|M.smegmatis_MC2_155 TRDRNGLPVPLKPYFEADWRFHQTILDHCGNGFLRRMVGSLGASVQRMRQ
Mflv_0958|M.gilvum_PYR-GCK AH---------------DLLLHDHILEAAGNNRARRIVRSLRESTRLLGG
Mvan_5910|M.vanbaalenii_PYR-1 LA---------------DKLFHQTLLEASGNEMFRALNGVVAEVLTGRTH
: :* . .
Mb0170c|M.bovis_AF2122/97 VFAADPRWGADAVNSHRQLIAALRRRDTAAVIEHTVWQFTDGARRLTEAL
Rv0165c|M.tuberculosis_H37Rv VRGRP----AMGRGRGEQSSAADRR---AAPPRHSRR---NRAHRLAVHR
MMAR_4029|M.marinum_M VFPGIEHWPARAVKDHRRVLVALKKHDDKAARTAMSEHLASSAVPLIDHL
MUL_3894|M.ulcerans_Agy99 VFPGIEHWPARAVKDHGQVLVALKKHDDKAARTAMSEHLASSAVPLIDHL
MAV_1576|M.avium_104 VFPAIQGWPEQSMKDHRRILSALKKRDDKLARAAMSEHLAAGAVPLIDHL
TH_3342|M.thermoresistible__bu VFPTISGWPARSTEHHRRVLAALADRDPDGARAAMSEHLAAGAGPLIEHL
MAB_1705c|M.abscessus_ATCC_199 RIRFASRDGRHSVALHEQIIARCEAGDSEGAGRAARDNWHTLIAAPEGAA
MSMEG_2546|M.smegmatis_MC2_155 NVHRGPVDTELAVAEHGRVLAAVETGDPQAAADAMRAHIEAVRERSIADA
Mflv_0958|M.gilvum_PYR-GCK ITADRSRTMSDIDAEHQPVVDAVIANDPAAAAAAMRTHLTSTGRLLVAQA
Mvan_5910|M.vanbaalenii_PYR-1 HGLMPEKPNIAAIALHDEVARAIRMGEEQQAERAMRAIIDESASAIVEDS
Mb0170c|M.bovis_AF2122/97 AETEVFG------------------
Rv0165c|M.tuberculosis_H37Rv WGTQADGGPG---------------
MMAR_4029|M.marinum_M IARGVVAESAPSGSAAERARGG---
MUL_3894|M.ulcerans_Agy99 IARGVVAESAPSGSAAERARGG---
MAV_1576|M.avium_104 VARGVVVD----GGGPDPG------
TH_3342|M.thermoresistible__bu KEHGVIAQ-----------------
MAB_1705c|M.abscessus_ATCC_199 HEERGAG------------------
MSMEG_2546|M.smegmatis_MC2_155 -------------------------
Mflv_0958|M.gilvum_PYR-GCK VRDQDSPLDAAAVWAEAVGANTELP
Mvan_5910|M.vanbaalenii_PYR-1 PPSD---------------------