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LIPTSTDLVEAYRRKEMSPVEATQAALDAIDSYDKSVNAFVLVDHEGALAAAKESEARWFSGEQLGPADG VPTSIKDALWTRGWPTLRGSTLIDEAGPWDEDAPSVARLREAGAVIIGKTTTPEYSWKGVTDSYRYGATV NPWDTTKTAGGSSGGSAAAVGLGMGPWSVGTDGGGSVRIPGGFTGTVALKPTYGLVPLYPMSAFGSLAHV GPMTRSVRDCAALLDVISRFDGRDGTAMPTPTSSFLDGLDAGVAGLRVAYSPNLGYVHNDPEVDAAVRAA VDVIAAAGAEVEEVDPGFADPVEAFHVLWFSGEAHVLRGYGDAVDDRVDPGLRRTAAIGATFSAADYLDA TAVRMDLGLRMGRFHQTYDLLLTPTLPLPAFPAGQDVPDGWHSPDWTSWTPYTYPFNLSQQPALTVPCGF TSAGLPIGLQVVGPRHSDSLVLRVGQAYQSATDWHLKTPKVLTGEGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2497 | - | - | 100% (467) | putative amidase |
| M. smegmatis MC2 155 | MSMEG_3970 | - | 5e-60 | 35.60% (455) | glutamyl-tRNA(Gln) amidotransferase subunit A |
| M. smegmatis MC2 155 | MSMEG_1090 | - | 5e-60 | 33.33% (456) | amidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3036c | gatA | 2e-58 | 35.08% (476) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. gilvum PYR-GCK | Mflv_4246 | gatA | 9e-60 | 35.20% (483) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. tuberculosis H37Rv | Rv3011c | gatA | 2e-58 | 35.08% (476) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. leprae Br4923 | MLBr_01702 | gatA | 8e-56 | 34.74% (475) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. abscessus ATCC 19977 | MAB_4415 | - | 1e-138 | 54.50% (444) | putative amidase |
| M. marinum M | MMAR_1702 | gatA | 2e-58 | 34.53% (472) | glutamyl-tRNA (Gln) amidotransferase (subunit A), GatA |
| M. avium 104 | MAV_3859 | gatA | 5e-58 | 34.74% (475) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. thermoresistible (build 8) | TH_2639 | - | 2e-59 | 35.08% (476) | PUTATIVE glutamyl-tRNA (Gln) amidotransferase (subunit A), GatA |
| M. ulcerans Agy99 | MUL_1939 | gatA | 1e-58 | 34.32% (472) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. vanbaalenii PYR-1 | Mvan_2115 | gatA | 1e-55 | 34.58% (483) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01702|M.leprae_Br4923 --MIGSLHEIIRLDASTLAAKIVAKELSSVEITQACLDQIEATDDTYRAF
MAV_3859|M.avium_104 ------MNEIIRSDAATLAARIAAKELSSVEATQACLDQIAATDERYHAF
Mb3036c|M.bovis_AF2122/97 ------MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAF
Rv3011c|M.tuberculosis_H37Rv ------MTDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAF
MMAR_1702|M.marinum_M ------MTDLIRSDAATLAAKIAAKEVSATELTQACLDQIEATDDRYHAF
MUL_1939|M.ulcerans_Agy99 ------MTDLIRSDAATLAAKIAAKEVSATELTQACLDQIEATDDRYHAF
Mflv_4246|M.gilvum_PYR-GCK ------MSELIKLDAATLADKISSKEVSSAEVTQAFLDQIAATDGDYHAF
Mvan_2115|M.vanbaalenii_PYR-1 ------MTDLIKLDAATLAAKIAAREVSATEVTQACLDQIAATDAEYHAF
TH_2639|M.thermoresistible__bu MSQGKSTDDLIRLDAATLGAKIAAKEISSTELTQACLDRIAATDDRYNAF
MSMEG_2497|M.smegmatis_MC2_155 ----------MIPTSTDLVEAYRRKEMSPVEATQAALDAIDSYDKSVNAF
MAB_4415|M.abscessus_ATCC_1997 ---MHKPTDPTEMTALELVAAYTSGELSPVEATAAVLSRIAQHDSAINAY
: * *:*..* * * *. * * .*:
MLBr_01702|M.leprae_Br4923 LHVAAEKALSAAAAVDK----AVAAGGQLSSTLAGVPLALKDVFTTVDMP
MAV_3859|M.avium_104 LHVAADEALGAAAVVDE----AVAAGERLPSPLAGVPLALKDVFTTVDMP
Mb3036c|M.bovis_AF2122/97 LHVAADEALAAAAAVDK----QVAAGEPLPSALAGVPLALKDVFTTSDMP
Rv3011c|M.tuberculosis_H37Rv LHVAADEALAAAAAIDK----QVAAGEPLPSALAGVPLALKDVFTTSDMP
MMAR_1702|M.marinum_M LHIGAHEALSAAAAVDT----ALAAGERLPSALAGVPLALKDVFTTVDMP
MUL_1939|M.ulcerans_Agy99 LHIGAHEALSAAAAVDT----ALAAGERLPSALAGVPLALKDVFTTVDMP
Mflv_4246|M.gilvum_PYR-GCK LHVGAEQALAAAQTVDR----AVAAGEHLPSPLAGVPLALKDVFTTTDMP
Mvan_2115|M.vanbaalenii_PYR-1 LHVAGDQALAAAATVDKAIHEATAAGERLPSPLAGVPLALKDVFTTTDMP
TH_2639|M.thermoresistible__bu LHVAANKALSAAARVDA----AVAAGEELPSPLAGVPLALKDVFTTIDMP
MSMEG_2497|M.smegmatis_MC2_155 VLVDHEGALAAAKESEA-----RWFSGEQLGPADGVPTSIKDALWTRGWP
MAB_4415|M.abscessus_ATCC_1997 CLVDEEAALAAATESEE-----RWRGHYTRGLLDGVPISIKDVFLTRNWP
: . **.** : . . *** ::**.: * . *
MLBr_01702|M.leprae_Br4923 TTCGSKILQG-WHSPYDATVTTRLRAAGIPILGKTNMDEFAMGSSTENSA
MAV_3859|M.avium_104 TTCGSKILQG-WRSPYDATVTTKLRAAGIPILGKTNMDEFAMGSSTENSA
Mb3036c|M.bovis_AF2122/97 TTCGSKILEG-WRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSA
Rv3011c|M.tuberculosis_H37Rv TTCGSKILEG-WRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSA
MMAR_1702|M.marinum_M TTCGSKILEG-WRSPYDATLTLRLRAAGIPILGKTNMDEFAMGSSTENSA
MUL_1939|M.ulcerans_Agy99 TTCGSKILEG-WRSPYDATLTLRLRAAGIPILGKTNMDEFAMGSSTENSA
Mflv_4246|M.gilvum_PYR-GCK TTCGSKVLEG-WTSPYDATVTAKLRSAGIPILGKTNMDEFAMGSSTENSA
Mvan_2115|M.vanbaalenii_PYR-1 TTCGSKILEG-WTSPYDATVTAKLRAAGIPILGKTNMDEFAMGSSTENSA
TH_2639|M.thermoresistible__bu TTCGSKILDG-WQAPYDATVTVALRAAGIPILGKTNLDEFAMGSSTENSA
MSMEG_2497|M.smegmatis_MC2_155 TLRGSTLIDEAGPWDEDAPSVARLREAGAVIIGKTTTPEYSWKGVTDSYR
MAB_4415|M.abscessus_ATCC_1997 TLRGSGLIDPDGPWDVDSPAVQRIRADGMVMVGKTTTPEFAWKGVTDSRQ
* ** ::: *:. . :* * ::***. *:: . *:.
MLBr_01702|M.leprae_Br4923 YGPTRNPWNVDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTA
MAV_3859|M.avium_104 YGPTRNPWNVERVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTA
Mb3036c|M.bovis_AF2122/97 YGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTA
Rv3011c|M.tuberculosis_H37Rv YGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTA
MMAR_1702|M.marinum_M YGPTRNPWNLDRVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTA
MUL_1939|M.ulcerans_Agy99 YGPTRNPWNLDRVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTA
Mflv_4246|M.gilvum_PYR-GCK YGPTRNPWDTERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTA
Mvan_2115|M.vanbaalenii_PYR-1 YGPTRNPWNVDCVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTA
TH_2639|M.thermoresistible__bu FGPTRNPWDVNRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTA
MSMEG_2497|M.smegmatis_MC2_155 YGATVNPWDTTKTAGGSSGGSAAAVGLGMGPWSVGTDGGGSVRIPGGFTG
MAB_4415|M.abscessus_ATCC_1997 RGITHNPADPSRTAGGSSGGSAAAVAAGMAPMSIGTDGGGSVRIPASFCG
* * ** : ..***.******:. .* ::*:* ***:* *..: .
MLBr_01702|M.leprae_Br4923 TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHAVIAGHDARD
MAV_3859|M.avium_104 TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDIRD
Mb3036c|M.bovis_AF2122/97 TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRD
Rv3011c|M.tuberculosis_H37Rv TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRD
MMAR_1702|M.marinum_M TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTAMLHQVIAGHDAKD
MUL_1939|M.ulcerans_Agy99 TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTAMLHQVIAGHDAKD
Mflv_4246|M.gilvum_PYR-GCK TVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPLD
Mvan_2115|M.vanbaalenii_PYR-1 TVGVKPTYGTVSRYGLIACASSLDQGGPCARTVLDTALLHQVIAGHDPRD
TH_2639|M.thermoresistible__bu TVGVKPTYGTVSRYGLVACASSLDQGGPCGRTVLDTALLHQVIAGHDAKD
MSMEG_2497|M.smegmatis_MC2_155 TVALKPTYGLVPLYPMSAFG-SLAHVGPMTRSVRDCAALLDVISRFDGRD
MAB_4415|M.abscessus_ATCC_1997 VVGFKPTHGRIPMYPISPFG-PLAHGGPITRTVEDAALLMDIISLPDYRD
.*..***:* :. * : . . .* : ** *:* * * * :*: * *
MLBr_01702|M.leprae_Br4923 STSVEAAVPDIVGAAKAGESGDLHGVRVGVVRQLRG-EGYQSGVLASFQA
MAV_3859|M.avium_104 STSVDAPVPDVVGAARAGAAGDLKGVRVGVVKQLRG-EGYQPGVLASFEA
Mb3036c|M.bovis_AF2122/97 STSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEA
Rv3011c|M.tuberculosis_H37Rv STSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEA
MMAR_1702|M.marinum_M STSLETEIPDVVGAAKAGASGDLRGVRIGVVKQLRG-DGYQPGVLASFEA
MUL_1939|M.ulcerans_Agy99 STSLETEIPDVVGAAKAGASGDLRGVRIGVVKQLRG-DGYQPGVLASFEA
Mflv_4246|M.gilvum_PYR-GCK STSVEAPVPDVVAAARTGAGGDLTGVRIGVVKQLRSGEGYQAGVLASFNA
Mvan_2115|M.vanbaalenii_PYR-1 STSVNAAVPDVVGAARAGARGDLKGVRIGVVKQLRSGEGYQPGVLASFTA
TH_2639|M.thermoresistible__bu STSLTAPVPDVVAAARAGASGDLKGVRVGVVRQLRG-EGIQPGVLASFDA
MSMEG_2497|M.smegmatis_MC2_155 GTAMPTPTSSFLDGLDAGVAG----LRVAYSPNLGY-VHNDPEVDAAVRA
MAB_4415|M.abscessus_ATCC_1997 PTSLSPTLTTYRSQVYRDMTG----LDIAYSPTLGY-VDVDPEVADLVEN
*:: . . . * : :. * :. * .
MLBr_01702|M.leprae_Br4923 AVEQLIALGATVSEVDCPHFDYALAAYYLILPSEVSSNLARFDAMRYGLR
MAV_3859|M.avium_104 AVEQLTALGAEVSEVDCPHFEYALAAYYLILPSEVSSNLARFDAMRYGLR
Mb3036c|M.bovis_AF2122/97 AVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLR
Rv3011c|M.tuberculosis_H37Rv AVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLR
MMAR_1702|M.marinum_M AVAQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLR
MUL_1939|M.ulcerans_Agy99 AVAQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLR
Mflv_4246|M.gilvum_PYR-GCK AVDQLTALGAEVTEVDCPHFDYSLPAYYLILPSEVSSNLAKFDGMRYGLR
Mvan_2115|M.vanbaalenii_PYR-1 AVEQLTALGAEVSEVDCPHFDHSLAAYYLILPSEVSSNLAKFDGMRYGLR
TH_2639|M.thermoresistible__bu AVEQLAALGAEVIEVDCPNIDHALAAYYLIMPSEVSSNLARFDAMRYGLR
MSMEG_2497|M.smegmatis_MC2_155 AVDVIAAAGAEVEEVD-PGFADPVEAFHVLWFSGEAHVLRGYG--DAVDD
MAB_4415|M.abscessus_ATCC_1997 AVNALNDAGLPVTHAD-PGFSDPIDSFETLWAAGAAASLNNYGALDDVGT
** : * * ..* * : .: :: : : : * :.
MLBr_01702|M.leprae_Br4923 VGDDGSRSAEEVIALTRAAGFGPEVKRRIMIGAYALSAGYYDSYYSQAQK
MAV_3859|M.avium_104 IGDDGSHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQK
Mb3036c|M.bovis_AF2122/97 VGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQK
Rv3011c|M.tuberculosis_H37Rv VGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQK
MMAR_1702|M.marinum_M IGDDGTHSAEEVMAMTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQK
MUL_1939|M.ulcerans_Agy99 IGDDGTHSAEEVMAMTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQK
Mflv_4246|M.gilvum_PYR-GCK AGDDGTHSAEEVMALTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQK
Mvan_2115|M.vanbaalenii_PYR-1 VGDDGTTSAEEVMAMTRAAGFGAEVKRRIMIGTYALSAGYYDAYYNQAQK
TH_2639|M.thermoresistible__bu VGDDGTRSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQK
MSMEG_2497|M.smegmatis_MC2_155 RVDPG------------------------LRRTAAIGATFSAADYLDATA
MAB_4415|M.abscessus_ATCC_1997 DIDPG------------------------LAQMWDTGAGASATEYLAARN
* * : .* : * *
MLBr_01702|M.leprae_Br4923 VRTLIARDLDKAYRSVDVLVSPATPTTAFSLGEKADDPLAMYLFDLCT--
MAV_3859|M.avium_104 VRTLIARDLDAAYESVDVVVSPATPTTAFGLGEKVDDPLAMYLFDLCT--
Mb3036c|M.bovis_AF2122/97 VRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCT--
Rv3011c|M.tuberculosis_H37Rv VRTLIARDLDAAYRSVDVLVSPTTPTTAFRMGEKVDDPLAMYLFDLCT--
MMAR_1702|M.marinum_M VRTLIARDLDEAYQSVDVLVSPATPTTAFPLGEKVDDPLAMYLFDLCT--
MUL_1939|M.ulcerans_Agy99 IRTLIARDLDEAYQSVDVLVSPATPTTAFPLGEKVDDPLAMYLFDLCT--
Mflv_4246|M.gilvum_PYR-GCK VRTLIARDLDAAYQKVDVLVSPATPTTAFRLGEKVDDPLSMYLFDLCT--
Mvan_2115|M.vanbaalenii_PYR-1 VRTLIARDLDEAYRSVDVLVSPATPSTAFRLGEKVDDPLAMYLFDLCT--
TH_2639|M.thermoresistible__bu VRTLVARDFDAAYEKVDVLVSPTTPTTAFPLGEKVDHPLAMYLFDLCT--
MSMEG_2497|M.smegmatis_MC2_155 VRMDLGLRMGRFHQTYDLLLTPTLPLPAFPAGQDVPDGWHSPDWTSWTPY
MAB_4415|M.abscessus_ATCC_1997 TCVQLGVTMGAFHELHNVLITPTVPIPAFPLGADVPPNSGMRWWAQWTPF
:. :. :. :::::*: * .** * .. : *
MLBr_01702|M.leprae_Br4923 -LPLNLAGHCGMSVPSGLSSDDDLPVGLQIMAPALADDRLYRVGAAYEAA
MAV_3859|M.avium_104 -LPLNLAGHCGMSVPSGLSPDDDLPVGLQIMAPALADDRLYRVGAAYEAA
Mb3036c|M.bovis_AF2122/97 -LPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAA
Rv3011c|M.tuberculosis_H37Rv -LPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAA
MMAR_1702|M.marinum_M -LPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAA
MUL_1939|M.ulcerans_Agy99 -LPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAA
Mflv_4246|M.gilvum_PYR-GCK -LPLNLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAA
Mvan_2115|M.vanbaalenii_PYR-1 -LPLNLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAA
TH_2639|M.thermoresistible__bu -LPLNLAGHCGMSVPSGLSPDDNLPVGLQIMAPALADDRLYRVGAAYEAA
MSMEG_2497|M.smegmatis_MC2_155 TYPFNLSQQPALTVPCGFTSAG-LPIGLQVVGPRHSDSLVLRVGQAYQSA
MAB_4415|M.abscessus_ATCC_1997 TYPFNMTQQPALSIPVGNTAQG-LPVGMQIVGPRHSDDLVLAVGHFAE--
*:*:: : .:::* * :. . **:*:*::.* :*. : ** :
MLBr_01702|M.leprae_Br4923 RG------PLPSAI--
MAV_3859|M.avium_104 RG------PLRSAI--
Mb3036c|M.bovis_AF2122/97 RG------PLLSAI--
Rv3011c|M.tuberculosis_H37Rv RG------PLLSAI--
MMAR_1702|M.marinum_M RG------PLPSAI--
MUL_1939|M.ulcerans_Agy99 RG------PLPSAI--
Mflv_4246|M.gilvum_PYR-GCK RG------PLPTAL--
Mvan_2115|M.vanbaalenii_PYR-1 RG------PLPTAL--
TH_2639|M.thermoresistible__bu RG------PLPAAV--
MSMEG_2497|M.smegmatis_MC2_155 TDWHLKTPKVLTGEGH
MAB_4415|M.abscessus_ATCC_1997 --------RVLAG---
: :.