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M. gilvum PYR-GCK Mflv_4246 (gatA)

annotation: aspartyl/glutamyl-tRNA amidotransferase subunit A
coordinates: 4507504 - 4508988
length: 494

SELIKLDAATLADKISSKEVSSAEVTQAFLDQIAATDGDYHAFLHVGAEQALAAAQTVDRAVAAGEHLPS
PLAGVPLALKDVFTTTDMPTTCGSKVLEGWTSPYDATVTAKLRSAGIPILGKTNMDEFAMGSSTENSAYG
PTRNPWDTERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASS
LDQGGPCARTVLDTALLHQVIAGHDPLDSTSVEAPVPDVVAAARTGAGGDLTGVRIGVVKQLRSGEGYQA
GVLASFNAAVDQLTALGAEVTEVDCPHFDYSLPAYYLILPSEVSSNLAKFDGMRYGLRAGDDGTHSAEEV
MALTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKVRTLIARDLDAAYQKVDVLVSPATPTTAFRLG
EKVDDPLSMYLFDLCTLPLNLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAARGPLP
TAL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4246gatA-100% (494)aspartyl/glutamyl-tRNA amidotransferase subunit A
M. gilvum PYR-GCKMflv_2712-3e-4332.18% (491) amidase
M. gilvum PYR-GCKMflv_1016-1e-3729.61% (510) amidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3036cgatA0.086.23% (494) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. tuberculosis H37RvRv3011cgatA0.086.03% (494) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. leprae Br4923MLBr_01702gatA0.084.41% (494) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. abscessus ATCC 19977MAB_3341cgatA0.085.02% (494) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. marinum MMMAR_1702gatA0.086.03% (494) glutamyl-tRNA (Gln) amidotransferase (subunit A), GatA
M. avium 104MAV_3859gatA0.087.25% (494) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. smegmatis MC2 155MSMEG_2365gatA0.088.03% (493) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. thermoresistible (build 8)TH_2639-0.085.16% (492) PUTATIVE glutamyl-tRNA (Gln) amidotransferase (subunit A), GatA
M. ulcerans Agy99MUL_1939gatA0.085.83% (494) aspartyl/glutamyl-tRNA amidotransferase subunit A
M. vanbaalenii PYR-1Mvan_2115gatA0.089.36% (498) aspartyl/glutamyl-tRNA amidotransferase subunit A

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4246|M.gilvum_PYR-GCK          ------MSELIKLDAATLADKISSKEVSSAEVTQAFLDQIAATDGDYHAF
Mvan_2115|M.vanbaalenii_PYR-1       ------MTDLIKLDAATLAAKIAAREVSATEVTQACLDQIAATDAEYHAF
MLBr_01702|M.leprae_Br4923          --MIGSLHEIIRLDASTLAAKIVAKELSSVEITQACLDQIEATDDTYRAF
MAV_3859|M.avium_104                ------MNEIIRSDAATLAARIAAKELSSVEATQACLDQIAATDERYHAF
Mb3036c|M.bovis_AF2122/97           ------MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAF
Rv3011c|M.tuberculosis_H37Rv        ------MTDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAF
MMAR_1702|M.marinum_M               ------MTDLIRSDAATLAAKIAAKEVSATELTQACLDQIEATDDRYHAF
MUL_1939|M.ulcerans_Agy99           ------MTDLIRSDAATLAAKIAAKEVSATELTQACLDQIEATDDRYHAF
MSMEG_2365|M.smegmatis_MC2_155      MS-----TELIRSDAATLGAKIAAKEVSSTEVTQAHLDQIAATDDRFHAF
TH_2639|M.thermoresistible__bu      MSQGKSTDDLIRLDAATLGAKIAAKEISSTELTQACLDRIAATDDRYNAF
MAB_3341c|M.abscessus_ATCC_199      ------MTDLIRQDAAALAALIHSGEVSSVEVTRAHLDQIASTDETYRAF
                                            ::*: **::*.  *   *:*:.* *:* **:* :**  :.**

Mflv_4246|M.gilvum_PYR-GCK          LHVGAEQALAAAQTVDR----AVAAGEHLPSPLAGVPLALKDVFTTTDMP
Mvan_2115|M.vanbaalenii_PYR-1       LHVAGDQALAAAATVDKAIHEATAAGERLPSPLAGVPLALKDVFTTTDMP
MLBr_01702|M.leprae_Br4923          LHVAAEKALSAAAAVDK----AVAAGGQLSSTLAGVPLALKDVFTTVDMP
MAV_3859|M.avium_104                LHVAADEALGAAAVVDE----AVAAGERLPSPLAGVPLALKDVFTTVDMP
Mb3036c|M.bovis_AF2122/97           LHVAADEALAAAAAVDK----QVAAGEPLPSALAGVPLALKDVFTTSDMP
Rv3011c|M.tuberculosis_H37Rv        LHVAADEALAAAAAIDK----QVAAGEPLPSALAGVPLALKDVFTTSDMP
MMAR_1702|M.marinum_M               LHIGAHEALSAAAAVDT----ALAAGERLPSALAGVPLALKDVFTTVDMP
MUL_1939|M.ulcerans_Agy99           LHIGAHEALSAAAAVDT----ALAAGERLPSALAGVPLALKDVFTTVDMP
MSMEG_2365|M.smegmatis_MC2_155      LHVAADSALAEAARVDA----AVAAGEQLPSPLAGVPLALKDVFTTTDMP
TH_2639|M.thermoresistible__bu      LHVAANKALSAAARVDA----AVAAGEELPSPLAGVPLALKDVFTTIDMP
MAB_3341c|M.abscessus_ATCC_199      LHVAGEQALAAAKDVDD----AIAAGS-VPSGLAGVPLALKDVFTTRDMP
                                    **:....**. *  :*       ***  :.* ************** ***

Mflv_4246|M.gilvum_PYR-GCK          TTCGSKVLEGWTSPYDATVTAKLRSAGIPILGKTNMDEFAMGSSTENSAY
Mvan_2115|M.vanbaalenii_PYR-1       TTCGSKILEGWTSPYDATVTAKLRAAGIPILGKTNMDEFAMGSSTENSAY
MLBr_01702|M.leprae_Br4923          TTCGSKILQGWHSPYDATVTTRLRAAGIPILGKTNMDEFAMGSSTENSAY
MAV_3859|M.avium_104                TTCGSKILQGWRSPYDATVTTKLRAAGIPILGKTNMDEFAMGSSTENSAY
Mb3036c|M.bovis_AF2122/97           TTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAY
Rv3011c|M.tuberculosis_H37Rv        TTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAY
MMAR_1702|M.marinum_M               TTCGSKILEGWRSPYDATLTLRLRAAGIPILGKTNMDEFAMGSSTENSAY
MUL_1939|M.ulcerans_Agy99           TTCGSKILEGWRSPYDATLTLRLRAAGIPILGKTNMDEFAMGSSTENSAY
MSMEG_2365|M.smegmatis_MC2_155      TTCGSKILEGWQSPYDATVTVKLRAAGIPILGKTNMDEFAMGSSTENSAY
TH_2639|M.thermoresistible__bu      TTCGSKILDGWQAPYDATVTVALRAAGIPILGKTNLDEFAMGSSTENSAF
MAB_3341c|M.abscessus_ATCC_199      TTCGSKILENWVPPYDATVTARLRGAGIPILGKTNMDEFAMGSSTENSAY
                                    ******:*:.* .*****:*  **.**********:*************:

Mflv_4246|M.gilvum_PYR-GCK          GPTRNPWDTERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTAT
Mvan_2115|M.vanbaalenii_PYR-1       GPTRNPWNVDCVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MLBr_01702|M.leprae_Br4923          GPTRNPWNVDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MAV_3859|M.avium_104                GPTRNPWNVERVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
Mb3036c|M.bovis_AF2122/97           GPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
Rv3011c|M.tuberculosis_H37Rv        GPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MMAR_1702|M.marinum_M               GPTRNPWNLDRVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTAT
MUL_1939|M.ulcerans_Agy99           GPTRNPWNLDRVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTAT
MSMEG_2365|M.smegmatis_MC2_155      GPTRNPWNTERVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTAT
TH_2639|M.thermoresistible__bu      GPTRNPWDVNRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MAB_3341c|M.abscessus_ATCC_199      GPTRNPWDVERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTAT
                                    *******: : ***************:*******:***************

Mflv_4246|M.gilvum_PYR-GCK          VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPLDS
Mvan_2115|M.vanbaalenii_PYR-1       VGVKPTYGTVSRYGLIACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
MLBr_01702|M.leprae_Br4923          VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHAVIAGHDARDS
MAV_3859|M.avium_104                VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDIRDS
Mb3036c|M.bovis_AF2122/97           VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
Rv3011c|M.tuberculosis_H37Rv        VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
MMAR_1702|M.marinum_M               VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTAMLHQVIAGHDAKDS
MUL_1939|M.ulcerans_Agy99           VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTAMLHQVIAGHDAKDS
MSMEG_2365|M.smegmatis_MC2_155      VGVKPTYGTVSRYGLIACASSLDQGGPCARTVLDTALLHAVIAGHDARDS
TH_2639|M.thermoresistible__bu      VGVKPTYGTVSRYGLVACASSLDQGGPCGRTVLDTALLHQVIAGHDAKDS
MAB_3341c|M.abscessus_ATCC_199      VGVKPTYGTVSRFGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
                                    ************:**:************.*******:** ******  **

Mflv_4246|M.gilvum_PYR-GCK          TSVEAPVPDVVAAARTGAGGDLTGVRIGVVKQLRSGEGYQAGVLASFNAA
Mvan_2115|M.vanbaalenii_PYR-1       TSVNAAVPDVVGAARAGARGDLKGVRIGVVKQLRSGEGYQPGVLASFTAA
MLBr_01702|M.leprae_Br4923          TSVEAAVPDIVGAAKAGESGDLHGVRVGVVRQLRG-EGYQSGVLASFQAA
MAV_3859|M.avium_104                TSVDAPVPDVVGAARAGAAGDLKGVRVGVVKQLRG-EGYQPGVLASFEAA
Mb3036c|M.bovis_AF2122/97           TSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAA
Rv3011c|M.tuberculosis_H37Rv        TSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAA
MMAR_1702|M.marinum_M               TSLETEIPDVVGAAKAGASGDLRGVRIGVVKQLRG-DGYQPGVLASFEAA
MUL_1939|M.ulcerans_Agy99           TSLETEIPDVVGAAKAGASGDLRGVRIGVVKQLRG-DGYQPGVLASFEAA
MSMEG_2365|M.smegmatis_MC2_155      TSVKADVPDVVAAARAGATGDLKGVRVGVVKQLRG-DGYQPGVLQSFNAA
TH_2639|M.thermoresistible__bu      TSLTAPVPDVVAAARAGASGDLKGVRVGVVRQLRG-EGIQPGVLASFDAA
MAB_3341c|M.abscessus_ATCC_199      TSVDEPVPDVVAAARAGASGDLKGVRVGVVTQLRG-DGYQPGVMASFDAA
                                    **:   :**:*.**::*  *** ***:*** **:. :* *.**: ** **

Mflv_4246|M.gilvum_PYR-GCK          VDQLTALGAEVTEVDCPHFDYSLPAYYLILPSEVSSNLAKFDGMRYGLRA
Mvan_2115|M.vanbaalenii_PYR-1       VEQLTALGAEVSEVDCPHFDHSLAAYYLILPSEVSSNLAKFDGMRYGLRV
MLBr_01702|M.leprae_Br4923          VEQLIALGATVSEVDCPHFDYALAAYYLILPSEVSSNLARFDAMRYGLRV
MAV_3859|M.avium_104                VEQLTALGAEVSEVDCPHFEYALAAYYLILPSEVSSNLARFDAMRYGLRI
Mb3036c|M.bovis_AF2122/97           VEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRV
Rv3011c|M.tuberculosis_H37Rv        VEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRV
MMAR_1702|M.marinum_M               VAQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRI
MUL_1939|M.ulcerans_Agy99           VAQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRI
MSMEG_2365|M.smegmatis_MC2_155      VEQLTALGAEVTEVDCPHFDHAMAAYYLILPSEVSSNLARFDAMRFGLRV
TH_2639|M.thermoresistible__bu      VEQLAALGAEVIEVDCPNIDHALAAYYLIMPSEVSSNLARFDAMRYGLRV
MAB_3341c|M.abscessus_ATCC_199      VEQLTALGADVVEVSCPHFEYALPAYYLILPSEVSSNLARFDAMRYGMRV
                                    * ** **** * **.**::::::.*****:*********:**.**:*:* 

Mflv_4246|M.gilvum_PYR-GCK          GDDGTHSAEEVMALTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKV
Mvan_2115|M.vanbaalenii_PYR-1       GDDGTTSAEEVMAMTRAAGFGAEVKRRIMIGTYALSAGYYDAYYNQAQKV
MLBr_01702|M.leprae_Br4923          GDDGSRSAEEVIALTRAAGFGPEVKRRIMIGAYALSAGYYDSYYSQAQKV
MAV_3859|M.avium_104                GDDGSHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
Mb3036c|M.bovis_AF2122/97           GDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
Rv3011c|M.tuberculosis_H37Rv        GDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
MMAR_1702|M.marinum_M               GDDGTHSAEEVMAMTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKV
MUL_1939|M.ulcerans_Agy99           GDDGTHSAEEVMAMTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKI
MSMEG_2365|M.smegmatis_MC2_155      GDDGTHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
TH_2639|M.thermoresistible__bu      GDDGTRSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
MAB_3341c|M.abscessus_ATCC_199      GDDGTHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYGRAQKV
                                    ****: *****:*:*******.*********:*********:**.:***:

Mflv_4246|M.gilvum_PYR-GCK          RTLIARDLDAAYQKVDVLVSPATPTTAFRLGEKVDDPLSMYLFDLCTLPL
Mvan_2115|M.vanbaalenii_PYR-1       RTLIARDLDEAYRSVDVLVSPATPSTAFRLGEKVDDPLAMYLFDLCTLPL
MLBr_01702|M.leprae_Br4923          RTLIARDLDKAYRSVDVLVSPATPTTAFSLGEKADDPLAMYLFDLCTLPL
MAV_3859|M.avium_104                RTLIARDLDAAYESVDVVVSPATPTTAFGLGEKVDDPLAMYLFDLCTLPL
Mb3036c|M.bovis_AF2122/97           RTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPL
Rv3011c|M.tuberculosis_H37Rv        RTLIARDLDAAYRSVDVLVSPTTPTTAFRMGEKVDDPLAMYLFDLCTLPL
MMAR_1702|M.marinum_M               RTLIARDLDEAYQSVDVLVSPATPTTAFPLGEKVDDPLAMYLFDLCTLPL
MUL_1939|M.ulcerans_Agy99           RTLIARDLDEAYQSVDVLVSPATPTTAFPLGEKVDDPLAMYLFDLCTLPL
MSMEG_2365|M.smegmatis_MC2_155      RTLIARDLDRAYENVDVLVSPATPTTAFGLGEKVDDPLAMYLFDLCTLPL
TH_2639|M.thermoresistible__bu      RTLVARDFDAAYEKVDVLVSPTTPTTAFPLGEKVDHPLAMYLFDLCTLPL
MAB_3341c|M.abscessus_ATCC_199      RTLIKRDLERAYEQVDVLVTPATPTTAFRLGEKVDDPLAMYQFDLCTLPL
                                    ***: **:: **..***:*:*:**:*** :***.*.**:** ********

Mflv_4246|M.gilvum_PYR-GCK          NLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAARGPL
Mvan_2115|M.vanbaalenii_PYR-1       NLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MLBr_01702|M.leprae_Br4923          NLAGHCGMSVPSGLSSDDDLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MAV_3859|M.avium_104                NLAGHCGMSVPSGLSPDDDLPVGLQIMAPALADDRLYRVGAAYEAARGPL
Mb3036c|M.bovis_AF2122/97           NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
Rv3011c|M.tuberculosis_H37Rv        NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MMAR_1702|M.marinum_M               NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MUL_1939|M.ulcerans_Agy99           NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MSMEG_2365|M.smegmatis_MC2_155      NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
TH_2639|M.thermoresistible__bu      NLAGHCGMSVPSGLSPDDNLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MAB_3341c|M.abscessus_ATCC_199      NLAGHCGMSVPSGLSADDGLPVGLQIMAPALADDRLYRVGAAYETARGAL
                                    ***************.**.*************************:***.*

Mflv_4246|M.gilvum_PYR-GCK          PTAL
Mvan_2115|M.vanbaalenii_PYR-1       PTAL
MLBr_01702|M.leprae_Br4923          PSAI
MAV_3859|M.avium_104                RSAI
Mb3036c|M.bovis_AF2122/97           LSAI
Rv3011c|M.tuberculosis_H37Rv        LSAI
MMAR_1702|M.marinum_M               PSAI
MUL_1939|M.ulcerans_Agy99           PSAI
MSMEG_2365|M.smegmatis_MC2_155      PSAL
TH_2639|M.thermoresistible__bu      PAAV
MAB_3341c|M.abscessus_ATCC_199      PAAL
                                     :*: