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TDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAFLHVAADEALAAAAAIDKQVAAGEPLPS ALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYG PTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASS LDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQP GVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEV MAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRMG EKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLL SAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3011c | gatA | - | 100% (494) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. tuberculosis H37Rv | Rv3375 | amiD | 1e-47 | 31.44% (493) | amidase AmiD |
| M. tuberculosis H37Rv | Rv2363 | amiA2 | 1e-46 | 32.79% (488) | amidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3036c | gatA | 0.0 | 99.39% (494) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. gilvum PYR-GCK | Mflv_4246 | gatA | 0.0 | 86.03% (494) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. leprae Br4923 | MLBr_01702 | gatA | 0.0 | 88.82% (492) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. abscessus ATCC 19977 | MAB_3341c | gatA | 0.0 | 85.02% (494) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. marinum M | MMAR_1702 | gatA | 0.0 | 90.89% (494) | glutamyl-tRNA (Gln) amidotransferase (subunit A), GatA |
| M. avium 104 | MAV_3859 | gatA | 0.0 | 91.09% (494) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. smegmatis MC2 155 | MSMEG_2365 | gatA | 0.0 | 88.84% (493) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. thermoresistible (build 8) | TH_2639 | - | 0.0 | 86.99% (492) | PUTATIVE glutamyl-tRNA (Gln) amidotransferase (subunit A), GatA |
| M. ulcerans Agy99 | MUL_1939 | gatA | 0.0 | 90.69% (494) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
| M. vanbaalenii PYR-1 | Mvan_2115 | gatA | 0.0 | 88.96% (498) | aspartyl/glutamyl-tRNA amidotransferase subunit A |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4246|M.gilvum_PYR-GCK ------MSELIKLDAATLADKISSKEVSSAEVTQAFLDQIAATDGDYHAF
Mvan_2115|M.vanbaalenii_PYR-1 ------MTDLIKLDAATLAAKIAAREVSATEVTQACLDQIAATDAEYHAF
Rv3011c|M.tuberculosis_H37Rv ------MTDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAF
Mb3036c|M.bovis_AF2122/97 ------MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAF
MMAR_1702|M.marinum_M ------MTDLIRSDAATLAAKIAAKEVSATELTQACLDQIEATDDRYHAF
MUL_1939|M.ulcerans_Agy99 ------MTDLIRSDAATLAAKIAAKEVSATELTQACLDQIEATDDRYHAF
MLBr_01702|M.leprae_Br4923 --MIGSLHEIIRLDASTLAAKIVAKELSSVEITQACLDQIEATDDTYRAF
MAV_3859|M.avium_104 ------MNEIIRSDAATLAARIAAKELSSVEATQACLDQIAATDERYHAF
MSMEG_2365|M.smegmatis_MC2_155 MS-----TELIRSDAATLGAKIAAKEVSSTEVTQAHLDQIAATDDRFHAF
TH_2639|M.thermoresistible__bu MSQGKSTDDLIRLDAATLGAKIAAKEISSTELTQACLDRIAATDDRYNAF
MAB_3341c|M.abscessus_ATCC_199 ------MTDLIRQDAAALAALIHSGEVSSVEVTRAHLDQIASTDETYRAF
::*: **::*. * *:*:.* *:* **:* :** :.**
Mflv_4246|M.gilvum_PYR-GCK LHVGAEQALAAAQTVDR----AVAAGEHLPSPLAGVPLALKDVFTTTDMP
Mvan_2115|M.vanbaalenii_PYR-1 LHVAGDQALAAAATVDKAIHEATAAGERLPSPLAGVPLALKDVFTTTDMP
Rv3011c|M.tuberculosis_H37Rv LHVAADEALAAAAAIDK----QVAAGEPLPSALAGVPLALKDVFTTSDMP
Mb3036c|M.bovis_AF2122/97 LHVAADEALAAAAAVDK----QVAAGEPLPSALAGVPLALKDVFTTSDMP
MMAR_1702|M.marinum_M LHIGAHEALSAAAAVDT----ALAAGERLPSALAGVPLALKDVFTTVDMP
MUL_1939|M.ulcerans_Agy99 LHIGAHEALSAAAAVDT----ALAAGERLPSALAGVPLALKDVFTTVDMP
MLBr_01702|M.leprae_Br4923 LHVAAEKALSAAAAVDK----AVAAGGQLSSTLAGVPLALKDVFTTVDMP
MAV_3859|M.avium_104 LHVAADEALGAAAVVDE----AVAAGERLPSPLAGVPLALKDVFTTVDMP
MSMEG_2365|M.smegmatis_MC2_155 LHVAADSALAEAARVDA----AVAAGEQLPSPLAGVPLALKDVFTTTDMP
TH_2639|M.thermoresistible__bu LHVAANKALSAAARVDA----AVAAGEELPSPLAGVPLALKDVFTTIDMP
MAB_3341c|M.abscessus_ATCC_199 LHVAGEQALAAAKDVDD----AIAAGS-VPSGLAGVPLALKDVFTTRDMP
**:....**. * :* *** :.* ************** ***
Mflv_4246|M.gilvum_PYR-GCK TTCGSKVLEGWTSPYDATVTAKLRSAGIPILGKTNMDEFAMGSSTENSAY
Mvan_2115|M.vanbaalenii_PYR-1 TTCGSKILEGWTSPYDATVTAKLRAAGIPILGKTNMDEFAMGSSTENSAY
Rv3011c|M.tuberculosis_H37Rv TTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAY
Mb3036c|M.bovis_AF2122/97 TTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAY
MMAR_1702|M.marinum_M TTCGSKILEGWRSPYDATLTLRLRAAGIPILGKTNMDEFAMGSSTENSAY
MUL_1939|M.ulcerans_Agy99 TTCGSKILEGWRSPYDATLTLRLRAAGIPILGKTNMDEFAMGSSTENSAY
MLBr_01702|M.leprae_Br4923 TTCGSKILQGWHSPYDATVTTRLRAAGIPILGKTNMDEFAMGSSTENSAY
MAV_3859|M.avium_104 TTCGSKILQGWRSPYDATVTTKLRAAGIPILGKTNMDEFAMGSSTENSAY
MSMEG_2365|M.smegmatis_MC2_155 TTCGSKILEGWQSPYDATVTVKLRAAGIPILGKTNMDEFAMGSSTENSAY
TH_2639|M.thermoresistible__bu TTCGSKILDGWQAPYDATVTVALRAAGIPILGKTNLDEFAMGSSTENSAF
MAB_3341c|M.abscessus_ATCC_199 TTCGSKILENWVPPYDATVTARLRGAGIPILGKTNMDEFAMGSSTENSAY
******:*:.* .*****:* **.**********:*************:
Mflv_4246|M.gilvum_PYR-GCK GPTRNPWDTERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTAT
Mvan_2115|M.vanbaalenii_PYR-1 GPTRNPWNVDCVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
Rv3011c|M.tuberculosis_H37Rv GPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
Mb3036c|M.bovis_AF2122/97 GPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MMAR_1702|M.marinum_M GPTRNPWNLDRVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTAT
MUL_1939|M.ulcerans_Agy99 GPTRNPWNLDRVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTAT
MLBr_01702|M.leprae_Br4923 GPTRNPWNVDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MAV_3859|M.avium_104 GPTRNPWNVERVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MSMEG_2365|M.smegmatis_MC2_155 GPTRNPWNTERVPGGSGGGSAAALAAYQAPLAIGSDTGGSIRQPAALTAT
TH_2639|M.thermoresistible__bu GPTRNPWDVNRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTAT
MAB_3341c|M.abscessus_ATCC_199 GPTRNPWDVERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTAT
*******: : ***************:*******:***************
Mflv_4246|M.gilvum_PYR-GCK VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPLDS
Mvan_2115|M.vanbaalenii_PYR-1 VGVKPTYGTVSRYGLIACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
Rv3011c|M.tuberculosis_H37Rv VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
Mb3036c|M.bovis_AF2122/97 VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
MMAR_1702|M.marinum_M VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTAMLHQVIAGHDAKDS
MUL_1939|M.ulcerans_Agy99 VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTAMLHQVIAGHDAKDS
MLBr_01702|M.leprae_Br4923 VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHAVIAGHDARDS
MAV_3859|M.avium_104 VGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDIRDS
MSMEG_2365|M.smegmatis_MC2_155 VGVKPTYGTVSRYGLIACASSLDQGGPCARTVLDTALLHAVIAGHDARDS
TH_2639|M.thermoresistible__bu VGVKPTYGTVSRYGLVACASSLDQGGPCGRTVLDTALLHQVIAGHDAKDS
MAB_3341c|M.abscessus_ATCC_199 VGVKPTYGTVSRFGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS
************:**:************.*******:** ****** **
Mflv_4246|M.gilvum_PYR-GCK TSVEAPVPDVVAAARTGAGGDLTGVRIGVVKQLRSGEGYQAGVLASFNAA
Mvan_2115|M.vanbaalenii_PYR-1 TSVNAAVPDVVGAARAGARGDLKGVRIGVVKQLRSGEGYQPGVLASFTAA
Rv3011c|M.tuberculosis_H37Rv TSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAA
Mb3036c|M.bovis_AF2122/97 TSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAA
MMAR_1702|M.marinum_M TSLETEIPDVVGAAKAGASGDLRGVRIGVVKQLRG-DGYQPGVLASFEAA
MUL_1939|M.ulcerans_Agy99 TSLETEIPDVVGAAKAGASGDLRGVRIGVVKQLRG-DGYQPGVLASFEAA
MLBr_01702|M.leprae_Br4923 TSVEAAVPDIVGAAKAGESGDLHGVRVGVVRQLRG-EGYQSGVLASFQAA
MAV_3859|M.avium_104 TSVDAPVPDVVGAARAGAAGDLKGVRVGVVKQLRG-EGYQPGVLASFEAA
MSMEG_2365|M.smegmatis_MC2_155 TSVKADVPDVVAAARAGATGDLKGVRVGVVKQLRG-DGYQPGVLQSFNAA
TH_2639|M.thermoresistible__bu TSLTAPVPDVVAAARAGASGDLKGVRVGVVRQLRG-EGIQPGVLASFDAA
MAB_3341c|M.abscessus_ATCC_199 TSVDEPVPDVVAAARAGASGDLKGVRVGVVTQLRG-DGYQPGVMASFDAA
**: :**:*.**::* *** ***:*** **:. :* *.**: ** **
Mflv_4246|M.gilvum_PYR-GCK VDQLTALGAEVTEVDCPHFDYSLPAYYLILPSEVSSNLAKFDGMRYGLRA
Mvan_2115|M.vanbaalenii_PYR-1 VEQLTALGAEVSEVDCPHFDHSLAAYYLILPSEVSSNLAKFDGMRYGLRV
Rv3011c|M.tuberculosis_H37Rv VEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRV
Mb3036c|M.bovis_AF2122/97 VEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRV
MMAR_1702|M.marinum_M VAQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRI
MUL_1939|M.ulcerans_Agy99 VAQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRI
MLBr_01702|M.leprae_Br4923 VEQLIALGATVSEVDCPHFDYALAAYYLILPSEVSSNLARFDAMRYGLRV
MAV_3859|M.avium_104 VEQLTALGAEVSEVDCPHFEYALAAYYLILPSEVSSNLARFDAMRYGLRI
MSMEG_2365|M.smegmatis_MC2_155 VEQLTALGAEVTEVDCPHFDHAMAAYYLILPSEVSSNLARFDAMRFGLRV
TH_2639|M.thermoresistible__bu VEQLAALGAEVIEVDCPNIDHALAAYYLIMPSEVSSNLARFDAMRYGLRV
MAB_3341c|M.abscessus_ATCC_199 VEQLTALGADVVEVSCPHFEYALPAYYLILPSEVSSNLARFDAMRYGMRV
* ** **** * **.**::::::.*****:*********:**.**:*:*
Mflv_4246|M.gilvum_PYR-GCK GDDGTHSAEEVMALTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKV
Mvan_2115|M.vanbaalenii_PYR-1 GDDGTTSAEEVMAMTRAAGFGAEVKRRIMIGTYALSAGYYDAYYNQAQKV
Rv3011c|M.tuberculosis_H37Rv GDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
Mb3036c|M.bovis_AF2122/97 GDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
MMAR_1702|M.marinum_M GDDGTHSAEEVMAMTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKV
MUL_1939|M.ulcerans_Agy99 GDDGTHSAEEVMAMTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKI
MLBr_01702|M.leprae_Br4923 GDDGSRSAEEVIALTRAAGFGPEVKRRIMIGAYALSAGYYDSYYSQAQKV
MAV_3859|M.avium_104 GDDGSHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
MSMEG_2365|M.smegmatis_MC2_155 GDDGTHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
TH_2639|M.thermoresistible__bu GDDGTRSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKV
MAB_3341c|M.abscessus_ATCC_199 GDDGTHSAEEVMALTRAAGFGPEVKRRIMIGTYALSAGYYDAYYGRAQKV
****: *****:*:*******.*********:*********:**.:***:
Mflv_4246|M.gilvum_PYR-GCK RTLIARDLDAAYQKVDVLVSPATPTTAFRLGEKVDDPLSMYLFDLCTLPL
Mvan_2115|M.vanbaalenii_PYR-1 RTLIARDLDEAYRSVDVLVSPATPSTAFRLGEKVDDPLAMYLFDLCTLPL
Rv3011c|M.tuberculosis_H37Rv RTLIARDLDAAYRSVDVLVSPTTPTTAFRMGEKVDDPLAMYLFDLCTLPL
Mb3036c|M.bovis_AF2122/97 RTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPL
MMAR_1702|M.marinum_M RTLIARDLDEAYQSVDVLVSPATPTTAFPLGEKVDDPLAMYLFDLCTLPL
MUL_1939|M.ulcerans_Agy99 RTLIARDLDEAYQSVDVLVSPATPTTAFPLGEKVDDPLAMYLFDLCTLPL
MLBr_01702|M.leprae_Br4923 RTLIARDLDKAYRSVDVLVSPATPTTAFSLGEKADDPLAMYLFDLCTLPL
MAV_3859|M.avium_104 RTLIARDLDAAYESVDVVVSPATPTTAFGLGEKVDDPLAMYLFDLCTLPL
MSMEG_2365|M.smegmatis_MC2_155 RTLIARDLDRAYENVDVLVSPATPTTAFGLGEKVDDPLAMYLFDLCTLPL
TH_2639|M.thermoresistible__bu RTLVARDFDAAYEKVDVLVSPTTPTTAFPLGEKVDHPLAMYLFDLCTLPL
MAB_3341c|M.abscessus_ATCC_199 RTLIKRDLERAYEQVDVLVTPATPTTAFRLGEKVDDPLAMYQFDLCTLPL
***: **:: **..***:*:*:**:*** :***.*.**:** ********
Mflv_4246|M.gilvum_PYR-GCK NLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAARGPL
Mvan_2115|M.vanbaalenii_PYR-1 NLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAARGPL
Rv3011c|M.tuberculosis_H37Rv NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
Mb3036c|M.bovis_AF2122/97 NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MMAR_1702|M.marinum_M NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MUL_1939|M.ulcerans_Agy99 NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MLBr_01702|M.leprae_Br4923 NLAGHCGMSVPSGLSSDDDLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MAV_3859|M.avium_104 NLAGHCGMSVPSGLSPDDDLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MSMEG_2365|M.smegmatis_MC2_155 NLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPL
TH_2639|M.thermoresistible__bu NLAGHCGMSVPSGLSPDDNLPVGLQIMAPALADDRLYRVGAAYEAARGPL
MAB_3341c|M.abscessus_ATCC_199 NLAGHCGMSVPSGLSADDGLPVGLQIMAPALADDRLYRVGAAYETARGAL
***************.**.*************************:***.*
Mflv_4246|M.gilvum_PYR-GCK PTAL
Mvan_2115|M.vanbaalenii_PYR-1 PTAL
Rv3011c|M.tuberculosis_H37Rv LSAI
Mb3036c|M.bovis_AF2122/97 LSAI
MMAR_1702|M.marinum_M PSAI
MUL_1939|M.ulcerans_Agy99 PSAI
MLBr_01702|M.leprae_Br4923 PSAI
MAV_3859|M.avium_104 RSAI
MSMEG_2365|M.smegmatis_MC2_155 PSAL
TH_2639|M.thermoresistible__bu PAAV
MAB_3341c|M.abscessus_ATCC_199 PAAL
:*: