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MSYPTTRPATWFVTGTSKGLGLELVRQLLARGDNVAATTRSTERLHAGLEGVDTGSLLPIEVDLADPSAV HKAVTATVERFGHLDVVVNNAGYGFLASVEDTTDADIRQMLDVQVIGTWNVLRAAIPHLRAARSGHIVNV SSILGLTAMPGWGLYCAGKFALNGMSEALAGEMAEFGVNVSIVEPGYFRTSFLTTDSLALPEATSDAYPG IHEMTQNHLALQGSQLGDPVKGAEAIIDIAVAGQGPLHQLLGSDSYEYAQAKVAALSGDIEAGRELAFTT DHR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1628 | - | - | 100% (283) | oxidoreductase, short chain dehydrogenase/reductase family protein |
M. smegmatis MC2 155 | MSMEG_0524 | - | 5e-54 | 40.88% (274) | short chain dehydrogenase |
M. smegmatis MC2 155 | MSMEG_2808 | - | 2e-46 | 38.32% (274) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1385 | fabG | 2e-23 | 35.14% (185) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. gilvum PYR-GCK | Mflv_0930 | - | 8e-42 | 35.51% (276) | short-chain dehydrogenase/reductase SDR |
M. tuberculosis H37Rv | Rv1350 | fabG | 2e-23 | 35.14% (185) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. leprae Br4923 | MLBr_01094 | - | 7e-22 | 34.78% (184) | short chain alcohol dehydrogenase |
M. abscessus ATCC 19977 | MAB_3405 | - | 8e-27 | 36.90% (187) | short chain dehydrogenase |
M. marinum M | MMAR_1614 | - | 3e-44 | 38.87% (247) | short chain dehydrogenase |
M. avium 104 | MAV_4982 | - | 8e-47 | 38.41% (276) | short-chain dehydrogenase/reductase SDR |
M. thermoresistible (build 8) | TH_3670 | - | 4e-39 | 37.60% (242) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_3423 | - | 4e-44 | 38.46% (247) | short chain dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_5466 | - | 1e-124 | 75.97% (283) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment Mb1385|M.bovis_AF2122/97 -MASLLNARTAVITGGAQG-LGLAIGQRFVAEGARVVLGDVNLEATEVAA Rv1350|M.tuberculosis_H37Rv -MASLLNARTAVITGGAQG-LGLAIGQRFVAEGARVVLGDVNLEATEVAA MSMEG_1628|M.smegmatis_MC2_155 MSYPTTRPATWFVTGTSKG-LGLELVRQLLARGDNVAATTRSTERLHAGL Mvan_5466|M.vanbaalenii_PYR-1 MPYPTDNPATWFVTGASRG-LGAELVRQLLRRGDNVAATTRSAERLSAAL MAV_4982|M.avium_104 ------MPKTWFITGSSRG-LGRALTTAVLDHGDHVVATARRPAQLDELV TH_3670|M.thermoresistible__bu MGSNVWGSKVWFITGASRG-FGREWAIAALDRGDRVAATARDVSTLDDLR MMAR_1614|M.marinum_M -------MSTWLITGCSTG-LGRALAEAVIDAGHHTVATARSVGGVADLV MUL_3423|M.ulcerans_Agy99 -------MSTWLITGCSTG-LGRALAEAVIDAGHHTVATARSVGGVADLA Mflv_0930|M.gilvum_PYR-GCK ------MSKRWFVTGGTPGGFGVAFAEAALEAGDRVVITSRRPHELAAWA MAB_3405|M.abscessus_ATCC_1997 --MDKITGKNIAITGAARG-IGYATATALLRRGARVVIGDRDVEALGSAV MLBr_01094|M.leprae_Br4923 --MEGFAGKVAVVTGAGSG-IGQALAIELARSGAKLAISDVDGEGLAQTE :** * :* * . . Mb1385|M.bovis_AF2122/97 KRLGGD-DVALAVRCDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDA Rv1350|M.tuberculosis_H37Rv KRLGGD-DVALAVRCDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDA MSMEG_1628|M.smegmatis_MC2_155 EGVDTG--SLLPIEVDLADPSAVHKAVTATVERFGHLDVVVNNAGYGFLA Mvan_5466|M.vanbaalenii_PYR-1 AGVDTG--RLLPLVVDLTDAAAVDGAVAAALDRFGRLDVVVNNAGYGFLG MAV_4982|M.avium_104 DRYGP---RIRACELDVTDRAAARRAIAAAVTAFGRIDVVVNNAGYANSA TH_3670|M.thermoresistible__bu DRFGD---AVLAMTLDVTDRAADFAAVQRAHDHFGRLDIVVNNAGYGHFG MMAR_1614|M.marinum_M QRSPE---RVLPLALDITEPDQITAAVQAAQQRFGGIDVLVNNAGYGYRA MUL_3423|M.ulcerans_Agy99 QRSPE---RVLPLALDITEPDQITAAMQAAQQRFGGIDVLVNNAGYGYRA Mflv_0930|M.gilvum_PYR-GCK DGYDD---RVLVVPLELTDAAQVQRVVQAAEEHFGGIDVLVNNAGRGWYG MAB_3405|M.abscessus_ATCC_1997 EGLKEE-GNVDAHPLDVTDPASFKRFLEAASAG-GPIDVLVNNAGVMPIG MLBr_01094|M.leprae_Br4923 GQLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTG :::: . * :: : **** . Mb1385|M.bovis_AF2122/97 TMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMSSVSG-K Rv1350|M.tuberculosis_H37Rv TMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMSSVSG-K MSMEG_1628|M.smegmatis_MC2_155 SVEDTTDADIRQMLDVQVIGTWNVLRAAIPHLRAARSGHIVNVSSILG-L Mvan_5466|M.vanbaalenii_PYR-1 AVEETTDAEIRQMLDVQVSGVWNVLRSAVPHLRAARSGHIINVSSILG-L MAV_4982|M.avium_104 PVEEVSDDDFRAQVETNFFGVVNVTKAALPVLHRQRAGHIVQISSVGGRV TH_3670|M.thermoresistible__bu FVEELTETEVRDQMETNFFGALWVTQAALPYLRRQRSGHIIQVSSIGG-V MMAR_1614|M.marinum_M AVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRARRSGAIVNISSIAVAL MUL_3423|M.ulcerans_Agy99 AVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRARRSGAIVNISSIAVAL Mflv_0930|M.gilvum_PYR-GCK SIEGMDESSLRAMFELNFFAVLSVTRAVLPGMRARGSGWIVNVSSVAG-L MAB_3405|M.abscessus_ATCC_1997 PFLSTSDRAIRSMLEVNLYGVINGCQLALPEMVARRRGQVVNIASVAG-L MLBr_01094|M.leprae_Br4923 DVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFG-L . . . . .. : . : * :::::*: Mb1385|M.bovis_AF2122/97 VGMVGQTNYSAAKAGIVGMTKAAAKELAHLG--IRVNAIAPGLIRS---- Rv1350|M.tuberculosis_H37Rv VGMVGQTNYSAAKAGIVGMTKAAAKELAHLG--IRVNAIAPGLIRS---- MSMEG_1628|M.smegmatis_MC2_155 TAMPGWGLYCAGKFALNGMSEALAGEMAEFG--VNVSIVEPGYFRT-SFL Mvan_5466|M.vanbaalenii_PYR-1 TAVPGWGLYCAGKFALNGMSEALAAELAGFG--IRVTIVEPGYFRT-DFL MAV_4982|M.avium_104 GGSPGIAAYQASKFAVAGFSEALAAEVAPLG--IKVTIAEPGALRT-EWA TH_3670|M.thermoresistible__bu SAFADLGAYHASKWALEGLSQSLSLEVAPFG--IHVTLIEPGGYAT-DWG MMAR_1614|M.marinum_M TPVG-SGYYAAAKAAMEGMSGALHGELAPLG--ISVTVVEPGAFRT-DFA MUL_3423|M.ulcerans_Agy99 TPVG-SGYYAAAKAAMEGMSGALHGELAPLG--ISVTVVEPGAFRT-DFA Mflv_0930|M.gilvum_PYR-GCK VAAPGFGYYSATKFAIEAVTDALRDEVSTHG--ISVLAVEPGAFRTNAYA MAB_3405|M.abscessus_ATCC_1997 MAVPGMAVYNASKFGVVGLSRALSDEFAPQG--VQVSAVLPTFTNTELIA MLBr_01094|M.leprae_Br4923 FSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKT---- * : * .: ..: : *.: * : * * : Mb1385|M.bovis_AF2122/97 ----------AMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDL Rv1350|M.tuberculosis_H37Rv ----------AMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDL MSMEG_1628|M.smegmatis_MC2_155 TTDSLALPEATSDAYPGIHEMTQNHLALQGSQLGDPVKGAEAIIDIAVAG Mvan_5466|M.vanbaalenii_PYR-1 TTESLALPTAAGDAYPAIREMTEQHLQLQGSQLGDPVKGAAAVIHVAVTG MAV_4982|M.avium_104 GSSMAVATVSP-DYESTVGAMNRRRAGFNRNAPGDPARAAHAIIEVVIAD TH_3670|M.thermoresistible__bu GSSARRSATMP-EYAESRAEADRVRS-QRVARPGDPKASAAALLKVVDAE MMAR_1614|M.marinum_M GRSLVQSTRMINDYAATAGQRRKENDTMHGNQPGDPAKAAAAIITAVESP MUL_3423|M.ulcerans_Agy99 GRSLVQSTRMINDYAATAGQRRKENDTMHGNQPGDPAKAAAAIITAVESP Mflv_0930|M.gilvum_PYR-GCK GFANKPVAETIPSYHDMLEEVRAAFVEMDGVQPGDPRRGARAVIAAMAQD MAB_3405|M.abscessus_ATCC_1997 GTDSTGAQKPVEPEDIAAAVVRIIEKPRVQVTVPKPLGAVTTIVNSLPTG MLBr_01094|M.leprae_Br4923 ------AIARNATAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVR-- .* . : Mb1385|M.bovis_AF2122/97 SS---YMTG----------------------TVLDVTGGRFI-------- Rv1350|M.tuberculosis_H37Rv SS---YMTG----------------------TVLDVTGGRFI-------- MSMEG_1628|M.smegmatis_MC2_155 QGPLHQLLG---------SDSYEYAQAKVAALSGDIEAGRELAFTTDHR- Mvan_5466|M.vanbaalenii_PYR-1 GGPLHQLLG---------SDAVSYAEAKIDALVADVKAGRDLALTTDHR- MAV_4982|M.avium_104 DPPLRLLLGSDALSAALAKSHQQIAEANRWAELSKSIDYPPVATPHRAAR TH_3670|M.thermoresistible__bu KPPLRVFFG---------ELPLQIVNADYQSRLQTWEEWQPIAVLAQG-- MMAR_1614|M.marinum_M APPAFLLLG------PDALMAYRHIAQRRDVEITDWEQLTAGTNLTP--- MUL_3423|M.ulcerans_Agy99 APPAFLLLG------PDALMAYRHIAQRRDVEITDWEQLTAGTNLTP--- Mflv_0930|M.gilvum_PYR-GCK PPPRRLVLG---------NSGYDAVIDALEQSLGDIRANETLSRSADFPT MAB_3405|M.abscessus_ATCC_1997 VRRFMSKKTG--------TDRVFLDFDTSARTAYENRAGSSLGVTKPDGE MLBr_01094|M.leprae_Br4923 KKKARVLVG--------PDAKVANVVVRFSGGAGYQRLFAQVASRLILNQ Mb1385|M.bovis_AF2122/97 -- Rv1350|M.tuberculosis_H37Rv -- MSMEG_1628|M.smegmatis_MC2_155 -- Mvan_5466|M.vanbaalenii_PYR-1 -- MAV_4982|M.avium_104 SR TH_3670|M.thermoresistible__bu -- MMAR_1614|M.marinum_M -- MUL_3423|M.ulcerans_Agy99 -- Mflv_0930|M.gilvum_PYR-GCK -- MAB_3405|M.abscessus_ATCC_1997 -- MLBr_01094|M.leprae_Br4923 R-