For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MWALAASAVLGSTVIGLAGPASAAPDCPDLHWIGVAGSGERDNPTLNGGMGRVVYRSLQDISRLVAQDGR TMTAEPVVYPAVEVPADGDLLGWGGFMSSVDTGVAALANQYTAFTQRCPQSKVVLAGYSQGAMVVHRNLH ALATSPNLAAALLVADGDRLPTDPTINLGTATMVPGAGKGVAQDWPILAHAPAPLPPTVGSRTISVCDRG DAVCDYDPDADEVTAAAIAVHTSYARSASQPWTWPLYQLLMPTVTNPAVPNPTVPIPTGPVPGPQAPTLQ ASPQNPLTGTETSVQPAEEPAPTLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1403 | - | - | 100% (305) | cutinase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_5878 | - | 2e-12 | 28.50% (214) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_2474 | - | 3e-09 | 27.83% (212) | cutinase Cut3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3482 | cut4 | 8e-09 | 27.78% (216) | cutinase precursor CUT4 |
| M. gilvum PYR-GCK | Mflv_5074 | - | 2e-93 | 67.06% (255) | cutinase |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 8e-09 | 27.78% (216) | cutinase precursor CUT4 |
| M. leprae Br4923 | MLBr_00099 | - | 1e-05 | 24.59% (244) | hypothetical protein MLBr_00099 |
| M. abscessus ATCC 19977 | MAB_3766 | - | 5e-10 | 26.92% (234) | cutinase cut3 precursor |
| M. marinum M | MMAR_1098 | cut3 | 2e-13 | 26.80% (291) | cutinase precursor, Cut3 |
| M. avium 104 | MAV_1682 | - | 2e-13 | 29.41% (238) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_1889 | - | 2e-87 | 64.82% (253) | cutinase superfamily protein |
| M. ulcerans Agy99 | MUL_0856 | cut3 | 1e-12 | 26.46% (291) | cutinase precursor, Cut3 |
| M. vanbaalenii PYR-1 | Mvan_1283 | - | 6e-98 | 67.29% (269) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5074|M.gilvum_PYR-GCK -----------------MIGMS--------------AGVAT-AQPAQP--
Mvan_1283|M.vanbaalenii_PYR-1 -----------------MRSVSGIAAAAAVVAATAVAGLTAGAASAQP--
MSMEG_1403|M.smegmatis_MC2_155 -----------------MWALAASAVLG-----STVIGLAG-PASAAP--
TH_1889|M.thermoresistible__bu -----------------LTALAGAAALAA--AALITSAVTAHTAAAAP--
Mb3482|M.bovis_AF2122/97 -MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTP--ALAPPASA--
Rv3452|M.tuberculosis_H37Rv -MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTP--ALAPPASA--
MAV_1682|M.avium_104 ----------------------MLGAGAMTAGATLLG---APLPASAA--
MMAR_1098|M.marinum_M ----------MNKHPLAVLAGALVTATGLLAAPSITGT--AIPSASAA--
MUL_0856|M.ulcerans_Agy99 ----------MNKHPLAVLAGALVTATGLLAAPSITGT--AIPSASAA--
MAB_3766|M.abscessus_ATCC_1997 -----MTTHQRGTRVGVVLSSFVVLTVLVLSAASVVGPVSAVPRASAD--
MLBr_00099|M.leprae_Br4923 MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLPPGV
.
Mflv_5074|M.gilvum_PYR-GCK --------------------ACPDVHWIGAAGSGERLGAG-AADGGMGRV
Mvan_1283|M.vanbaalenii_PYR-1 --------------------ACPDVHWIGAAGSGERAGAI-AADGGMGRV
MSMEG_1403|M.smegmatis_MC2_155 --------------------DCPDLHWIGVAGSGERDNP--TLNGGMGRV
TH_1889|M.thermoresistible__bu --------------------DCPDIHWIGAAGSGERDGDL-TADAGMGTT
Mb3482|M.bovis_AF2122/97 --------------------GCPDAEVVFARGTGE--------PPGLGRV
Rv3452|M.tuberculosis_H37Rv --------------------GCPDAEVVFARGTGE--------PPGLGRV
MAV_1682|M.avium_104 --------------------PCPDIEVTFARGTAE--------PPGVGGV
MMAR_1098|M.marinum_M --------------------DCPDAEVVFARGTSE--------PPGIGRV
MUL_0856|M.ulcerans_Agy99 --------------------DCPDAEVVFPRGTSE--------PPGIGRV
MAB_3766|M.abscessus_ATCC_1997 --------------------PCSDVDVSFARGRKE--------PVGLGRV
MLBr_00099|M.leprae_Br4923 LPIPSTAPHPRKPRPAFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQFPD
*.* . * *
Mflv_5074|M.gilvum_PYR-GCK IAKSYRDFAGLIQQSGRTITAEAVNYPAVAVPEDGGILDWAGFMGSVDTG
Mvan_1283|M.vanbaalenii_PYR-1 VAKSYRDFAALIQQSGRTITAEAVNYPATPVPEDGGILDWAGFMSSVDTG
MSMEG_1403|M.smegmatis_MC2_155 VYRSLQDISRLVAQDGRTMTAEPVVYPAVEVPADGDLLGWGGFMSSVDTG
TH_1889|M.thermoresistible__bu VYRSYQEFRELAQRDGRTITAEAVEYPAVPVPGEGEVLGWAGFLSSVRTG
Mb3482|M.bovis_AF2122/97 GQAFVSSL--RQQT-NKSIGTYGVNYPANGD-----------FLAAADG-
Rv3452|M.tuberculosis_H37Rv GQAFVSSL--RQQT-NKSIGTYGVNYPANGD-----------FLAAADG-
MAV_1682|M.avium_104 GQAFVEAL--RSQAGARSLGVYPVNYPADDD-----------FAASASAG
MMAR_1098|M.marinum_M GEAFVDSL--RQQT-GKNIGVYAVNYPASRL-----------QLHGGDG-
MUL_0856|M.ulcerans_Agy99 GEAFVDSL--RQQT-GKNIGVYAVNYPASRL-----------QLHGGDG-
MAB_3766|M.abscessus_ATCC_1997 GDEFVDSLTPRVQATGATMNVYPVNYDAG-------------IFSAGGG-
MLBr_00099|M.leprae_Br4923 ALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQ-MTYNDSRAEG
: : . : * * .
Mflv_5074|M.gilvum_PYR-GCK TAALGQQYQAFVAQCPTSQVVLAGYSQGAMVVHRNLHSLDASP-----NL
Mvan_1283|M.vanbaalenii_PYR-1 TAALGQQYQAFVAQCPTSQVVLAGYSQGAMVVHRNLHSLDGNP-----NL
MSMEG_1403|M.smegmatis_MC2_155 VAALANQYTAFTQRCPQSKVVLAGYSQGAMVVHRNLHALATSP-----NL
TH_1889|M.thermoresistible__bu AEALGNQYAAFVQRCPDTTVVLAGYSQGAMVVHRNLHALAGSP-----NF
Mb3482|M.bovis_AF2122/97 ANDASDHIQQMASACRATRLVLGGYSQGAAVID----IVTAAP-----LP
Rv3452|M.tuberculosis_H37Rv ANDASDHIQQMASACRATRLVLGGYSQGAAVID----IVTAAP-----LP
MAV_1682|M.avium_104 AGDASAHVQSMVADCPNTKLVLGGYSQGAMVID----LITIAQ-----AP
MMAR_1098|M.marinum_M ANDVISHVKSMASSCPNTKIVLGGYSQGADVID----IVAGVP-----LA
MUL_0856|M.ulcerans_Agy99 ANDVISHVKSMASSCPNTKIVQGGYSQGADVID----IVAGVP-----LA
MAB_3766|M.abscessus_ATCC_1997 ANDLSNHLQSVAASCPRTKLVIGGYSMGAEVID----TIIGVP-----NV
MLBr_00099|M.leprae_Br4923 TRAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDDDL
. . . * : * *:* ** : :
Mflv_5074|M.gilvum_PYR-GCK AAALLVADGDRLPQDPTVNIGSVTAVPGAGKGVAQDWPIL-AHAP-APLP
Mvan_1283|M.vanbaalenii_PYR-1 AAALLVADGDRLPQDPTINIGSVVTVPGAGKGVAQDWPIL-AHAP-APLP
MSMEG_1403|M.smegmatis_MC2_155 AAALLVADGDRLPTDPTINLGTATMVPGAGKGVAQDWPIL-AHAP-APLP
TH_1889|M.thermoresistible__bu GAALLVADGDRLPGDTTVDMGTVTAVSRPSMGVAQDWPIL-AGPPTTPLP
Mb3482|M.bovis_AF2122/97 GLGFT----QPLPPAADDHIAAIALFGNPSGR---------AGGLMSALT
Rv3452|M.tuberculosis_H37Rv GLGFT----QPLPPAADDHIAAIALFGNPSGR---------AGGLMSALT
MAV_1682|M.avium_104 VAGLIP---QTLNADQAEHVSALALFGNPSDRY--------LGAPVSVVS
MMAR_1098|M.marinum_M GISFG----NELPAQYADNIAAVAVFGNVANR---------SGGSLTTQS
MUL_0856|M.ulcerans_Agy99 GISFG----NELPAQYADNIAAVAVFGNVANR---------SGGSLTTQS
MAB_3766|M.abscessus_ATCC_1997 GIGFN----RPLPPTVGDRIVAIATFGNATHR---------TGGPLSGIA
MLBr_00099|M.leprae_Br4923 VLGVTLIADGRRQQGVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTGAR
.. : . :
Mflv_5074|M.gilvum_PYR-GCK V----TMGARTISVCNLGDAVCDYDP-DAEDEMNPAAVAVHTS-YARKAG
Mvan_1283|M.vanbaalenii_PYR-1 V----TLGAKTISVCELGDAVCDYDP-DAEDEMNPAAVAVHTS-YARSTA
MSMEG_1403|M.smegmatis_MC2_155 P----TVGSRTISVCDRGDAVCDYDP-DAD-EVTAAAIAVHTS-YARSAS
TH_1889|M.thermoresistible__bu P----SVGSRTISVCDIGDPVCDYDP-AAGSAMTAEGVAIHTS-YVSGHG
Mb3482|M.bovis_AF2122/97 P----QFGSKTINLCNNGDPICSDGN----------RWRAHLG-YVP-GM
Rv3452|M.tuberculosis_H37Rv P----QFGSKTINLCNNGDPICSDGN----------RWRAHLG-YVP-GM
MAV_1682|M.avium_104 P----WYGAKAIDLCAPGDPVCTPGGPLALPSHDEMVSPAHLS-YRQSGM
MMAR_1098|M.marinum_M S----LLGSKSIDLCNPSDPICHSGP--------GNDWNGHTDGYVP-TY
MUL_0856|M.ulcerans_Agy99 S----LLGSKSIDLCNPSDPICHSGP--------GNDWNGHTDGYVP-TY
MAB_3766|M.abscessus_ATCC_1997 G----VFGSRAIDLCNQGDPICMAGP--------NNSWDAHTS-YERTGL
MLBr_00099|M.leprae_Br4923 PGGFGVLHSRTNEICAPGDLICAAPA----EAFSVANLPATLNTLASGAG
::: .:* .* :* .
Mflv_5074|M.gilvum_PYR-GCK AMDSWTVPLYQLVT---------QRQAPLPAYPVQ---------------
Mvan_1283|M.vanbaalenii_PYR-1 SMDPWTVPLYQLTAG--------HPPVPAPITPLN---------------
MSMEG_1403|M.smegmatis_MC2_155 --QPWTWPLYQLLMPTVTNPAVPNPTVPIPTGPVPGPQAPTLQASPQNPL
TH_1889|M.thermoresistible__bu ESLPWTAPLYRMLG---------SAPESVQLAAAEG--------------
Mb3482|M.bovis_AF2122/97 TNQAARFVASRI--------------------------------------
Rv3452|M.tuberculosis_H37Rv TNQAARFVASRI--------------------------------------
MAV_1682|M.avium_104 PAQAATFVAAHL--------------------------------------
MMAR_1098|M.marinum_M TTQAASFVAAKLAAS---------SMAPVVQLPGPVPRAPGPAPQAPGPA
MUL_0856|M.ulcerans_Agy99 TTQAASFVAAKLAAS---------SMAPVVRLPGPVPRAPGPAPQAPGPA
MAB_3766|M.abscessus_ATCC_1997 PAEAAAFVASKLNRH---------GESEAE--------------------
MLBr_00099|M.leprae_Br4923 QPIHAMYATAQFWDLDG-------APATVWTLNWVHRLIEGAPHPKHG--
::
Mflv_5074|M.gilvum_PYR-GCK ---------VTAGS----
Mvan_1283|M.vanbaalenii_PYR-1 ---------AVTPAP---
MSMEG_1403|M.smegmatis_MC2_155 TGTETSVQPAEEPAPTLG
TH_1889|M.thermoresistible__bu ------------------
Mb3482|M.bovis_AF2122/97 ------------------
Rv3452|M.tuberculosis_H37Rv ------------------
MAV_1682|M.avium_104 ------------------
MMAR_1098|M.marinum_M TASPGTPVGATGTLVGAH
MUL_0856|M.ulcerans_Agy99 TASPGTPVGATGTLVGAH
MAB_3766|M.abscessus_ATCC_1997 ------------------
MLBr_00099|M.leprae_Br4923 ------------------