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IGMSAGVATAQPAQPACPDVHWIGAAGSGERLGAGAADGGMGRVIAKSYRDFAGLIQQSGRTITAEAVNY PAVAVPEDGGILDWAGFMGSVDTGTAALGQQYQAFVAQCPTSQVVLAGYSQGAMVVHRNLHSLDASPNLA AALLVADGDRLPQDPTVNIGSVTAVPGAGKGVAQDWPILAHAPAPLPVTMGARTISVCNLGDAVCDYDPD AEDEMNPAAVAVHTSYARKAGAMDSWTVPLYQLVTQRQAPLPAYPVQVTAGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5074 | - | - | 100% (263) | cutinase |
| M. gilvum PYR-GCK | Mflv_1037 | - | 1e-14 | 29.19% (209) | cutinase |
| M. gilvum PYR-GCK | Mflv_4966 | - | 2e-11 | 29.69% (229) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3482 | cut4 | 1e-10 | 27.78% (198) | cutinase precursor CUT4 |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 1e-10 | 27.78% (198) | cutinase precursor CUT4 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3766 | - | 3e-09 | 27.56% (225) | cutinase cut3 precursor |
| M. marinum M | MMAR_3837 | - | 2e-11 | 26.86% (242) | cutinase precursor |
| M. avium 104 | MAV_2961 | - | 5e-13 | 30.04% (233) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_1403 | - | 2e-93 | 67.06% (255) | cutinase superfamily protein |
| M. thermoresistible (build 8) | TH_1889 | - | 2e-82 | 61.98% (242) | cutinase superfamily protein |
| M. ulcerans Agy99 | MUL_0855 | cut4 | 4e-11 | 30.05% (193) | cutinase precursor, Cut4 |
| M. vanbaalenii PYR-1 | Mvan_1283 | - | 1e-126 | 86.90% (252) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3837|M.marinum_M ------MCQHQNVNARQSTRLLGVGLATICAALLSAPLI----IASASAA
MAV_2961|M.avium_104 ------------------------MLSPFWALLLGPALVGT--AAPAAAD
Mb3482|M.bovis_AF2122/97 -----MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTPALAPPASA
Rv3452|M.tuberculosis_H37Rv -----MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTPALAPPASA
MUL_0855|M.ulcerans_Agy99 MWLFPLDAQKWARSGRGRTRLARRCAGLVATTIAACAVLLAFPLVPKAAA
MAB_3766|M.abscessus_ATCC_1997 --------MTTHQRGTRVGVVLSSFVVLTVLVLSAASVVGPVSAVPRASA
Mflv_5074|M.gilvum_PYR-GCK --------------------MIGMS--------------AGVAT-AQPAQ
Mvan_1283|M.vanbaalenii_PYR-1 --------------------MRSVSGIAAAAAVVAATAVAGLTAGAASAQ
MSMEG_1403|M.smegmatis_MC2_155 --------------------MWALAASAVLG-----STVIGLAG-PASAA
TH_1889|M.thermoresistible__bu --------------------LTALAGAAALAA--AALITSAVTAHTAAAA
. .:
MMAR_3837|M.marinum_M A-CPDAEVTFARGTAE-------PPGVGGVGQAFIDSLRSQLGG--RSLG
MAV_2961|M.avium_104 S-CPDVEVVFARGTSE-------PPGVGRIGQSFVDTLRSRLGT--KSVG
Mb3482|M.bovis_AF2122/97 G-CPDAEVVFARGTGE-------PPGLGRVGQAFVSSLRQQTN---KSIG
Rv3452|M.tuberculosis_H37Rv G-CPDAEVVFARGTGE-------PPGLGRVGQAFVSSLRQQTN---KSIG
MUL_0855|M.ulcerans_Agy99 A-CPDVQVVFARGTGE-------PPGLGRVGNAMVASLRQKTD---QSIG
MAB_3766|M.abscessus_ATCC_1997 DPCSDVDVSFARGRKE-------PVGLGRVGDEFVDSLTPRVQATGATMN
Mflv_5074|M.gilvum_PYR-GCK PACPDVHWIGAAGSGERLGAGAADGGMGRVIAKSYRDFAGLIQQSGRTIT
Mvan_1283|M.vanbaalenii_PYR-1 PACPDVHWIGAAGSGERAGAIAADGGMGRVVAKSYRDFAALIQQSGRTIT
MSMEG_1403|M.smegmatis_MC2_155 PDCPDLHWIGVAGSGERDNP-TLNGGMGRVVYRSLQDISRLVAQDGRTMT
TH_1889|M.thermoresistible__bu PDCPDIHWIGAAGSGERDGDLTADAGMGTTVYRSYQEFRELAQRDGRTIT
*.* . . * * *:* : ::
MMAR_3837|M.marinum_M VYAVNYPATED-----------WPPSASAGATDASTHVESMAASCPNTKL
MAV_2961|M.avium_104 VYPVNYPATTD-----------FP-TAADGISDAGAHVQQMAANCPRTKM
Mb3482|M.bovis_AF2122/97 TYGVNYPANGD-----------FL-AAADGANDASDHIQQMASACRATRL
Rv3452|M.tuberculosis_H37Rv TYGVNYPANGD-----------FL-AAADGANDASDHIQQMASACRATRL
MUL_0855|M.ulcerans_Agy99 AYAVNYPANKD-----------FL-AAADGANDASDHVQQMTNECPNTKL
MAB_3766|M.abscessus_ATCC_1997 VYPVNYDAG--------------IFSAGGGANDLSNHLQSVAASCPRTKL
Mflv_5074|M.gilvum_PYR-GCK AEAVNYPAVAVPEDGGILDWAGFMGSVDTGTAALGQQYQAFVAQCPTSQV
Mvan_1283|M.vanbaalenii_PYR-1 AEAVNYPATPVPEDGGILDWAGFMSSVDTGTAALGQQYQAFVAQCPTSQV
MSMEG_1403|M.smegmatis_MC2_155 AEPVVYPAVEVPADGDLLGWGGFMSSVDTGVAALANQYTAFTQRCPQSKV
TH_1889|M.thermoresistible__bu AEAVEYPAVPVPGEGEVLGWAGFLSSVRTGAEALGNQYAAFVQRCPDTTV
. * * * :. * . : .. * : :
MMAR_3837|M.marinum_M VLGGYSQGAMVID----LITIARAPVAGFIPQTLS---AEVADHVAAVAV
MAV_2961|M.avium_104 VLGGYSQGAAVMG----FVTESAVPDGVQLVQSLQPMPAAVANHVAAVAL
Mb3482|M.bovis_AF2122/97 VLGGYSQGAAVID----IVTAAPLP-GLGFTQPLP---PAADDHIAAIAL
Rv3452|M.tuberculosis_H37Rv VLGGYSQGAAVID----IVTAAPLP-GLGFTQPLP---PAADDHIAAIAL
MUL_0855|M.ulcerans_Agy99 VLGGYSQGAAVIN----IVTAAPLP-GLGFTQPLP---AQAAQHVAAVTL
MAB_3766|M.abscessus_ATCC_1997 VIGGYSMGAEVID----TIIGVPNV-GIGFNRPLP---PTVGDRIVAIAT
Mflv_5074|M.gilvum_PYR-GCK VLAGYSQGAMVVHRNLHSLDASPNLAAALLVADGDRLPQDPTVNIGSVTA
Mvan_1283|M.vanbaalenii_PYR-1 VLAGYSQGAMVVHRNLHSLDGNPNLAAALLVADGDRLPQDPTINIGSVVT
MSMEG_1403|M.smegmatis_MC2_155 VLAGYSQGAMVVHRNLHALATSPNLAAALLVADGDRLPTDPTINLGTATM
TH_1889|M.thermoresistible__bu VLAGYSQGAMVVHRNLHALAGSPNFGAALLVADGDRLPGDTTVDMGTVTA
*:.*** ** *: : . : : : .
MMAR_3837|M.marinum_M FGNPTDRYLG-------GPISEISPWYGHKAIDLCAPNDPICTPGALALP
MAV_2961|M.avium_104 FGKPSAQFMSII----NEPPVTIGPLYAAKTIELCVPGDPICS-GAVNP-
Mb3482|M.bovis_AF2122/97 FGNPSGRAGG--------LMSALTPQFGSKTINLCNNGDPICSDGNRWR-
Rv3452|M.tuberculosis_H37Rv FGNPSGRAGG--------LMSALTPQFGSKTINLCNNGDPICSDGNRWR-
MUL_0855|M.ulcerans_Agy99 FGNPSGRAGG--------LMTALSPHFGGKILNLCNTGDPICSDGDQWK-
MAB_3766|M.abscessus_ATCC_1997 FGNATHRTGG--------PLSGIAGVFGSRAIDLCNQGDPICMAGPNNS-
Mflv_5074|M.gilvum_PYR-GCK VPGAGKGVAQDWPILAHAP-APLPVTMGARTISVCNLGDAVCDYDPDAED
Mvan_1283|M.vanbaalenii_PYR-1 VPGAGKGVAQDWPILAHAP-APLPVTLGAKTISVCELGDAVCDYDPDAED
MSMEG_1403|M.smegmatis_MC2_155 VPGAGKGVAQDWPILAHAP-APLPPTVGSRTISVCDRGDAVCDYDPDAD-
TH_1889|M.thermoresistible__bu VSRPSMGVAQDWPILAGPPTTPLPPSVGSRTISVCDIGDPVCDYDPAAGS
. . : . : :.:* .*.:* .
MMAR_3837|M.marinum_M SHDEMFSAAHLSYAQSGMPSQAATFVVSQL--------------------
MAV_2961|M.avium_104 -------AAHRQYVEAGMVDQAVDFTTDRV--------------------
Mb3482|M.bovis_AF2122/97 --------AHLGYVP-GMTNQAARFVASRI--------------------
Rv3452|M.tuberculosis_H37Rv --------AHLGYVP-GMTNQAARFVASRI--------------------
MUL_0855|M.ulcerans_Agy99 --------AHTGYVP-GLTNKAASFVAGRI--------------------
MAB_3766|M.abscessus_ATCC_1997 ------WDAHTSYERTGLPAEAAAFVASKLNRHGESEAE-----------
Mflv_5074|M.gilvum_PYR-GCK EMNPAAVAVHTSYARKAGAMDSWTVPLYQLVT---------QRQAPLPAY
Mvan_1283|M.vanbaalenii_PYR-1 EMNPAAVAVHTSYARSTASMDPWTVPLYQLTAG--------HPPVPAPIT
MSMEG_1403|M.smegmatis_MC2_155 EVTAAAIAVHTSYARSAS--QPWTWPLYQLLMPTVTNPAVPNPTVPIPTG
TH_1889|M.thermoresistible__bu AMTAEGVAIHTSYVSGHGESLPWTAPLYRMLG---------SAPESVQLA
* * . ::
MMAR_3837|M.marinum_M ------------------------------------
MAV_2961|M.avium_104 ------------------------------------
Mb3482|M.bovis_AF2122/97 ------------------------------------
Rv3452|M.tuberculosis_H37Rv ------------------------------------
MUL_0855|M.ulcerans_Agy99 ------------------------------------
MAB_3766|M.abscessus_ATCC_1997 ------------------------------------
Mflv_5074|M.gilvum_PYR-GCK PVQ------------------------VTAGS----
Mvan_1283|M.vanbaalenii_PYR-1 PLN------------------------AVTPAP---
MSMEG_1403|M.smegmatis_MC2_155 PVPGPQAPTLQASPQNPLTGTETSVQPAEEPAPTLG
TH_1889|M.thermoresistible__bu AAEG--------------------------------