For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NKHPLAVLAGALVTATGLLAAPSITGTAIPSASAADCPDAEVVFPRGTSEPPGIGRVGEAFVDSLRQQTG KNIGVYAVNYPASRLQLHGGDGANDVISHVKSMASSCPNTKIVQGGYSQGADVIDIVAGVPLAGISFGNE LPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSIDLCNPSDPICHSGPGNDWNGHTDGYVPTYTTQ AASFVAAKLAASSMAPVVRLPGPVPRAPGPAPQAPGPATASPGTPVGATGTLVGAH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0856 | cut3 | - | 100% (267) | cutinase precursor, Cut3 |
| M. ulcerans Agy99 | MUL_0855 | cut4 | 3e-57 | 52.56% (215) | cutinase precursor, Cut4 |
| M. ulcerans Agy99 | MUL_1597 | cut1 | 2e-34 | 42.86% (217) | cutinase Cut1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3481 | cut3 | 2e-95 | 67.82% (261) | cutinase precursor CUT3 |
| M. gilvum PYR-GCK | Mflv_4965 | - | 3e-47 | 46.45% (211) | cutinase |
| M. tuberculosis H37Rv | Rv3451 | cut3 | 2e-95 | 67.82% (261) | cutinase precursor CUT3 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3766 | - | 1e-52 | 48.17% (218) | cutinase cut3 precursor |
| M. marinum M | MMAR_1098 | cut3 | 1e-152 | 98.88% (267) | cutinase precursor, Cut3 |
| M. avium 104 | MAV_4394 | - | 6e-88 | 60.85% (258) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_2095 | - | 4e-75 | 58.20% (256) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_3765 | - | 7e-42 | 42.15% (223) | PUTATIVE Cutinase |
| M. vanbaalenii PYR-1 | Mvan_1441 | - | 9e-52 | 50.93% (214) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0856|M.ulcerans_Agy99 -------MNKHPLAVL--------AGALVTATGLLAAPSI-TGTAI--PS
MMAR_1098|M.marinum_M -------MNKHPLAVL--------AGALVTATGLLAAPSI-TGTAI--PS
Mb3481|M.bovis_AF2122/97 -------MNNRPIRLLTSGRAGLGAGALITAVVLLIALGA-VWT----PV
Rv3451|M.tuberculosis_H37Rv -------MNNRPIRLLTSGRAGLGAGALITAVVLLIALGA-VWT----PV
MAV_4394|M.avium_104 -------MKTHRIGRL----LGLGSSALITAAGLLGAP-----AAV--PV
MSMEG_2095|M.smegmatis_MC2_155 -------MLSRRIG----------AWALMAAGIALVVP-----ARL--PV
MAB_3766|M.abscessus_ATCC_1997 -------MTTHQRGTRVG--VVLSSFVVLTVLVLSAASVVGPVSAV--PR
Mflv_4965|M.gilvum_PYR-GCK -------MKIDLEVV-TRGVRALVAAAVAAGVLVVAPAVAAPRSLP---A
Mvan_1441|M.vanbaalenii_PYR-1 -------MMIDLDAP-ARRATGVLAAILVA----AATLVAAPVQIP---A
TH_3765|M.thermoresistible__bu MVGTMGEVNSDLELPGTRRTVALLTAALFLAAGLVTGSAVSPASAPLAPV
: : :
MUL_0856|M.ulcerans_Agy99 ASAADCPDAEVVFPRGTSEPPGIGRVGEAFVDSL--RQQT-GKNIGVYAV
MMAR_1098|M.marinum_M ASAADCPDAEVVFARGTSEPPGIGRVGEAFVDSL--RQQT-GKNIGVYAV
Mb3481|M.bovis_AF2122/97 AFADGCPDAEVTFARGTGEPPGIGRVGQAFVDSL--RQQT-GMEIGVYPV
Rv3451|M.tuberculosis_H37Rv AFADGCPDAEVTFARGTGEPPGIGRVGQAFVDSL--RQQT-GMEIGVYPV
MAV_4394|M.avium_104 ASADDCPDVEVIFARGTNEPPGMGRVGDAFVESL--RQQTSGLNIDTYGV
MSMEG_2095|M.smegmatis_MC2_155 ASAAECPDAEVVFARGTDEPAGLGRVGTAFVDAL--RKQAAGLEIDAYAV
MAB_3766|M.abscessus_ATCC_1997 ASADPCSDVDVSFARGRKEPVGLGRVGDEFVDSLTPRVQATGATMNVYPV
Mflv_4965|M.gilvum_PYR-GCK AGAQGCTDIQVVFARGTDEPPGLGRVGSAFVESL--RGRVGGRSVGSYAV
Mvan_1441|M.vanbaalenii_PYR-1 AHAQGCPDIEVVFARGTDEPPGLGRVGAAFVDSL--RGRVGGRSVGTYAV
TH_3765|M.thermoresistible__bu AQAAPCPDVEVIFARGRVESPGPGIIGNAFVNSL--RSKT-DKNVSLYAV
* * *.* :* *.** *. * * :* **::* * :. . :. * *
MUL_0856|M.ulcerans_Agy99 NYPASRLQLHGGDGANDVISHVKSMASSCPNTKIVQGGYSQGADVIDIVA
MMAR_1098|M.marinum_M NYPASRLQLHGGDGANDVISHVKSMASSCPNTKIVLGGYSQGADVIDIVA
Mb3481|M.bovis_AF2122/97 NYAASRLQLHGGDGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVA
Rv3451|M.tuberculosis_H37Rv NYAASRLQLHGGDGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVA
MAV_4394|M.avium_104 NYAASKLQLHGGDGANDTINRIKQAVQKCPNTKIVLGGYSQGASVMDIVA
MSMEG_2095|M.smegmatis_MC2_155 DYKAGKLQLSGGDGAKDAIAHIKSTVSSCSNTKIVLGGYSQGASVVNIAA
MAB_3766|M.abscessus_ATCC_1997 NYDAG--IFSAGGGANDLSNHLQSVAASCPRTKLVIGGYSMGAEVIDTII
Mflv_4965|M.gilvum_PYR-GCK AYPATFDFLAAAGGANDASNHIQWMMANCPSTRLVLGGYSQGAAVIDVIA
Mvan_1441|M.vanbaalenii_PYR-1 NYPASFDFLAAAAGANDASLHIQYMMANCPRTRLVLGGYSQGAAVIDVIA
TH_3765|M.thermoresistible__bu QYPADY---EIDIGANDMSRRIQHMAATCPDTRLVLGGYSLGAAVTDVVL
* * **:* ::: .*. *::* **** ** * :
MUL_0856|M.ulcerans_Agy99 GVPLAGISFGNELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSI
MMAR_1098|M.marinum_M GVPLAGISFGNELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSI
Mb3481|M.bovis_AF2122/97 GVPLGSISFGSPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAI
Rv3451|M.tuberculosis_H37Rv GVPLGSISFGSPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAI
MAV_4394|M.avium_104 GVPIGGINWGSSITPDLASHVAAVATFGDVADRAGGTLPSQSALLGSKAI
MSMEG_2095|M.smegmatis_MC2_155 GNQLGGITWADPLPAQYANNVAAIVTFGDIATRTGEALSTRSNLFGSKAI
MAB_3766|M.abscessus_ATCC_1997 GVPNVGIGFNRPLPPTVGDRIVAIATFGNATHRTGGPLSGIAGVFGSRAI
Mflv_4965|M.gilvum_PYR-GCK AVPFPAVGFDRPLPPNAPDFIAAIALFGNPTTKVG-LPITASPVWGTRSI
Mvan_1441|M.vanbaalenii_PYR-1 AVPIPAVGFNAPLPPNTPDFVAAIAVFGNPSTKLG-IPITASPVWGSRSI
TH_3765|M.thermoresistible__bu AVPISALGFDSPLPAGVDRHIAAIALFGNGIAWAG-PISNFSPLYAERTI
. .: : :.. :.*:. **: * : : . ::*
MUL_0856|M.ulcerans_Agy99 DLCNPSDPICHSGPGN------DWNGHTDGYVPTYTTQAASFVAAKLAAS
MMAR_1098|M.marinum_M DLCNPSDPICHSGPGN------DWNGHTDGYVPTYTTQAASFVAAKLAAS
Mb3481|M.bovis_AF2122/97 DLCNPTDPICHVGPGN------EFSGHIDGYIPTYTTQAASFVVQRLRAG
Rv3451|M.tuberculosis_H37Rv DLCNPTDPICHVGPGN------EFSGHIDGYIPTYTTQAASFVVQRLRAG
MAV_4394|M.avium_104 DLCNPNDPICHAGPGN------EWSGHTEGYVPVYTTQAAAFVASKL-MG
MSMEG_2095|M.smegmatis_MC2_155 DLCNPSDPICHAGQGN------EWSGHTDGYVPVYTTQAAVFAAAKLRAG
MAB_3766|M.abscessus_ATCC_1997 DLCNQGDPICMAGPNN------SWDAHTSYERTGLPAEAAAFVASKLNRH
Mflv_4965|M.gilvum_PYR-GCK DLCNGADPVCSAGD--------DIAAHSNYGPAGFTDQAAAFVAGLV---
Mvan_1441|M.vanbaalenii_PYR-1 DLCNGLDPVCSGGD--------DIAAHSNYGPGMFTDQAAAFVAGRL---
TH_3765|M.thermoresistible__bu ELCHGADPICNPADPETWRDNWSDHAATKYVQSGMVDQAADFVAARL---
:**: **:* . . . . :** *.. :
MUL_0856|M.ulcerans_Agy99 SMAPV-------------------------------VRLPGPVP------
MMAR_1098|M.marinum_M SMAPV-------------------------------VQLPGPVP------
Mb3481|M.bovis_AF2122/97 SVP----------------------------------HLPGSVP------
Rv3451|M.tuberculosis_H37Rv SVP----------------------------------HLPGSVP------
MAV_4394|M.avium_104 AGQSVPGYGPSVPGAGP-QSPGYGQQS-----PVYGQTPPGSGPSIHDNA
MSMEG_2095|M.smegmatis_MC2_155 SGRSVPGYG-TVPEYGPGYGPGYGSGNGQGYGPLYGPATPGYDPESPTHG
MAB_3766|M.abscessus_ATCC_1997 GESEAE--------------------------------------------
Mflv_4965|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1441|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3765|M.thermoresistible__bu --------------------------------------------------
MUL_0856|M.ulcerans_Agy99 RAPGPAPQAPGPATASPGTPVGATGTLVGAH---------
MMAR_1098|M.marinum_M RAPGPAPQAPGPATASPGTPVGATGTLVGAH---------
Mb3481|M.bovis_AF2122/97 QLPGSVLQMPG--TAAP-----APESLHGR----------
Rv3451|M.tuberculosis_H37Rv QLPGSVLQMPG--TAAP-----APESLHGR----------
MAV_4394|M.avium_104 PGPGTAPAPA--VPSTP------PSQAP------LV----
MSMEG_2095|M.smegmatis_MC2_155 PPPGYVPAPPGYVPETPGYELPGPSAAEPSAEVGLVSAVG
MAB_3766|M.abscessus_ATCC_1997 ----------------------------------------
Mflv_4965|M.gilvum_PYR-GCK ----------------------------------------
Mvan_1441|M.vanbaalenii_PYR-1 ----------------------------------------
TH_3765|M.thermoresistible__bu ----------------------------------------