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LRSVSGIAAAAAVVAATAVAGLTAGAASAQPACPDVHWIGAAGSGERAGAIAADGGMGRVVAKSYRDFAA LIQQSGRTITAEAVNYPATPVPEDGGILDWAGFMSSVDTGTAALGQQYQAFVAQCPTSQVVLAGYSQGAM VVHRNLHSLDGNPNLAAALLVADGDRLPQDPTINIGSVVTVPGAGKGVAQDWPILAHAPAPLPVTLGAKT ISVCELGDAVCDYDPDAEDEMNPAAVAVHTSYARSTASMDPWTVPLYQLTAGHPPVPAPITPLNAVTPAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1283 | - | - | 100% (280) | cutinase |
| M. vanbaalenii PYR-1 | Mvan_5793 | - | 7e-20 | 31.36% (236) | cutinase |
| M. vanbaalenii PYR-1 | Mvan_1440 | - | 1e-19 | 35.10% (245) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3751 | cut5 | 2e-11 | 30.84% (227) | cutinase precursor CUT5 |
| M. gilvum PYR-GCK | Mflv_5074 | - | 1e-126 | 86.90% (252) | cutinase |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 3e-10 | 29.11% (213) | cutinase precursor CUT4 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3809c | - | 5e-11 | 25.81% (310) | cutinase Cut4 |
| M. marinum M | MMAR_3837 | - | 4e-13 | 28.97% (252) | cutinase precursor |
| M. avium 104 | MAV_2961 | - | 4e-13 | 28.57% (238) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_1403 | - | 5e-98 | 67.29% (269) | cutinase superfamily protein |
| M. thermoresistible (build 8) | TH_1889 | - | 2e-87 | 58.94% (263) | cutinase superfamily protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 9e-12 | 31.28% (243) | cutinase, Cut5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3751|M.bovis_AF2122/97 ------MDVIRW----ARRLAVVAGTAAAVTTPGLLSAHVPMVSAEPCPD
MUL_4327|M.ulcerans_Agy99 ------MRNATW----TRRLAVGAATAVTALVGG--GIRVPFVAAEPCPD
MAV_2961|M.avium_104 ------MLSPFW----ALLLGPALVGTAAP------------AAADSCPD
MMAR_3837|M.marinum_M MCQHQNVNARQS----TRLLGVGLATICAALLSAP--LIIASASAAACPD
Rv3452|M.tuberculosis_H37Rv MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTPALAPPASAG-CPD
MAB_3809c|M.abscessus_ATCC_199 ----MNRYVKRG----SVGVSIFAVSAAAAVLANP-SENSAIAAAAGCPD
Mvan_1283|M.vanbaalenii_PYR-1 ---------------MRSVSGIAAAAAVVAATAVAGLTAGAASAQPACPD
Mflv_5074|M.gilvum_PYR-GCK ---------------MIGMS--------------AGVAT-AQPAQPACPD
MSMEG_1403|M.smegmatis_MC2_155 ---------------MWALAASAVLG-----STVIGLAG-PASAAPDCPD
TH_1889|M.thermoresistible__bu ---------------LTALAGAAALAA--AALITSAVTAHTAAAAPDCPD
: ***
Mb3751|M.bovis_AF2122/97 VEVVFARGTGE----PPGIGSVGGLFVDALR-----SQVGAKSLGVYAVN
MUL_4327|M.ulcerans_Agy99 VEVLFARGTGE----PPGIGGIGGSFVAALR-----SDIGAKSSAVYAID
MAV_2961|M.avium_104 VEVVFARGTSE----PPGVGRIGQSFVDTLR-----SRLGTKSVGVYPVN
MMAR_3837|M.marinum_M AEVTFARGTAE----PPGVGGVGQAFIDSLR-----SQLGGRSLGVYAVN
Rv3452|M.tuberculosis_H37Rv AEVVFARGTGE----PPGLGRVGQAFVSSLR-----QQTN-KSIGTYGVN
MAB_3809c|M.abscessus_ATCC_199 VDVSFARGTND----SPGLGDVGKAFTDELT-----DRLAGKSVDIYAVN
Mvan_1283|M.vanbaalenii_PYR-1 VHWIGAAGSGERAGAIAADGGMGRVVAKSYRDFAALIQQSGRTITAEAVN
Mflv_5074|M.gilvum_PYR-GCK VHWIGAAGSGERLGAGAADGGMGRVIAKSYRDFAGLIQQSGRTITAEAVN
MSMEG_1403|M.smegmatis_MC2_155 LHWIGVAGSGERDNP-TLNGGMGRVVYRSLQDISRLVAQDGRTMTAEPVV
TH_1889|M.thermoresistible__bu IHWIGAAGSGERDGDLTADAGMGTTVYRSYQEFRELAQRDGRTITAEAVE
. . *: : . . :* . :: :
Mb3751|M.bovis_AF2122/97 YPAS--------NDFASSDFPKTVIDGIRDAGSHIQSMAMSCPQTRQVLG
MUL_4327|M.ulcerans_Agy99 YPAS--------SDFSSSDFPRTVIDGIRDASSHIESMAAKCPATREVLG
MAV_2961|M.avium_104 YPAT--------TDFP------TAADGISDAGAHVQQMAANCPRTKMVLG
MMAR_3837|M.marinum_M YPAT--------EDWPP-----SASAGATDASTHVESMAASCPNTKLVLG
Rv3452|M.tuberculosis_H37Rv YPAN--------GDFL------AAADGANDASDHIQQMASACRATRLVLG
MAB_3809c|M.abscessus_ATCC_199 YPAS--------FDWVR------AGDGANDMSYHVQEVARNCPNTQFVLG
Mvan_1283|M.vanbaalenii_PYR-1 YPATPVPEDGGILDWAG--FMSSVDTGTAALGQQYQAFVAQCPTSQVVLA
Mflv_5074|M.gilvum_PYR-GCK YPAVAVPEDGGILDWAG--FMGSVDTGTAALGQQYQAFVAQCPTSQVVLA
MSMEG_1403|M.smegmatis_MC2_155 YPAVEVPADGDLLGWGG--FMSSVDTGVAALANQYTAFTQRCPQSKVVLA
TH_1889|M.thermoresistible__bu YPAVPVPGEGEVLGWAG--FLSSVRTGAEALGNQYAAFVQRCPDTTVVLA
*** .: . * . : .. * : **.
Mb3751|M.bovis_AF2122/97 GYSQGAAVAG----YVTSAVVPPAVPVQAVPAPMAPEVANHVAAVTLFGA
MUL_4327|M.ulcerans_Agy99 GYSQGAAVAG----YVTSASVPPGVPAAAVPKPMAPDIADYVAAVTLFGT
MAV_2961|M.avium_104 GYSQGAAVMG----FVTESAVPDGVQLVQSLQPMPAAVANHVAAVALFGK
MMAR_3837|M.marinum_M GYSQGAMVID----LITIARAP---VAGFIPQTLSAEVADHVAAVAVFGN
Rv3452|M.tuberculosis_H37Rv GYSQGAAVID----IVTAAPLP----GLGFTQPLPPAADDHIAAIALFGN
MAB_3809c|M.abscessus_ATCC_199 GFSQGAAVVD----VLFGTNGT----GLTFNNPLPTDLEKRVAAIVLIGN
Mvan_1283|M.vanbaalenii_PYR-1 GYSQGAMVVHRNLHSLDGNPNLAAALLVADGDRLPQDPTINIGSVVTVPG
Mflv_5074|M.gilvum_PYR-GCK GYSQGAMVVHRNLHSLDASPNLAAALLVADGDRLPQDPTVNIGSVTAVPG
MSMEG_1403|M.smegmatis_MC2_155 GYSQGAMVVHRNLHALATSPNLAAALLVADGDRLPTDPTINLGTATMVPG
TH_1889|M.thermoresistible__bu GYSQGAMVVHRNLHALAGSPNFGAALLVADGDRLPGDTTVDMGTVTAVSR
*:**** * : :. :.: . .
Mb3751|M.bovis_AF2122/97 PSAQFLGQY----GAPPIAIGPLYQPKTLQLCADGDSICG---------D
MUL_4327|M.ulcerans_Agy99 PSEQFLQHY----GAPPITIGPLYQPRTIELCASGDPVCS---------G
MAV_2961|M.avium_104 PSAQFMSII----NEPPVTIGPLYAAKTIELCVPGDPICS---------G
MMAR_3837|M.marinum_M PTDRYL-------GGPISEISPWYGHKAIDLCAPNDPICTPGALALPSHD
Rv3452|M.tuberculosis_H37Rv PS----GRA----GGLMSALTPQFGSKTINLCNNGDPICS---------D
MAB_3809c|M.abscessus_ATCC_199 PKNWQVAG-----MNLDLSIRDDQRSKIIDICNPGDGICDP--------N
Mvan_1283|M.vanbaalenii_PYR-1 AGKGVAQDWPILAHAP-APLPVTLGAKTISVCELGDAVCDYDPDAEDEMN
Mflv_5074|M.gilvum_PYR-GCK AGKGVAQDWPILAHAP-APLPVTMGARTISVCNLGDAVCDYDPDAEDEMN
MSMEG_1403|M.smegmatis_MC2_155 AGKGVAQDWPILAHAP-APLPPTVGSRTISVCDRGDAVCDYDPDAD-EVT
TH_1889|M.thermoresistible__bu PSMGVAQDWPILAGPPTTPLPPSVGSRTISVCDIGDPVCDYDPAAGSAMT
. : : :.:* .* :*
Mb3751|M.bovis_AF2122/97 GNSPVAHGLYAVNGMVGQGANFAASRL-----------------------
MUL_4327|M.ulcerans_Agy99 GNDAAAHALYAVNGMTGQGADFAAHHL-----------------------
MAV_2961|M.avium_104 AVNPAAHRQYVEAGMVDQAVDFTTDRV-----------------------
MMAR_3837|M.marinum_M EMFSAAHLSYAQSGMPSQAATFVVSQL-----------------------
Rv3452|M.tuberculosis_H37Rv GNRWRAHLGYVP-GMTNQAARFVASRI-----------------------
MAB_3809c|M.abscessus_ATCC_199 GGGLGPHMQYKSDGSADKAADFVAGRLAAVAASSSAAAASSSTSTTASGV
Mvan_1283|M.vanbaalenii_PYR-1 PAAVAVHTSYARSTASMDPWTVPLYQLTAG--------HPPVPAPITPLN
Mflv_5074|M.gilvum_PYR-GCK PAAVAVHTSYARKAGAMDSWTVPLYQLVT---------QRQAPLPAYPVQ
MSMEG_1403|M.smegmatis_MC2_155 AAAIAVHTSYARSAS--QPWTWPLYQLLMPTVTNPAVPNPTVPIPTGPVP
TH_1889|M.thermoresistible__bu AEGVAIHTSYVSGHGESLPWTAPLYRMLG---------SAPESVQLAAAE
* * ::
Mb3751|M.bovis_AF2122/97 --------------------------------------------------
MUL_4327|M.ulcerans_Agy99 --------------------------------------------------
MAV_2961|M.avium_104 --------------------------------------------------
MMAR_3837|M.marinum_M --------------------------------------------------
Rv3452|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3809c|M.abscessus_ATCC_199 PASTSKSANPLSATTAPAPTSASPAPASSPSSSTPKPVAASTSRRVPAWM
Mvan_1283|M.vanbaalenii_PYR-1 ------------------------AVTPAP--------------------
Mflv_5074|M.gilvum_PYR-GCK ------------------------VTAGS---------------------
MSMEG_1403|M.smegmatis_MC2_155 GPQAPTLQASPQNPLTGTETSVQPAEEPAPTLG-----------------
TH_1889|M.thermoresistible__bu G-------------------------------------------------
Mb3751|M.bovis_AF2122/97 ------------------------------------
MUL_4327|M.ulcerans_Agy99 ------------------------------------
MAV_2961|M.avium_104 ------------------------------------
MMAR_3837|M.marinum_M ------------------------------------
Rv3452|M.tuberculosis_H37Rv ------------------------------------
MAB_3809c|M.abscessus_ATCC_199 MPATDAPAAEVPAAVTSTIPAPDPARHGPLPGPGGQ
Mvan_1283|M.vanbaalenii_PYR-1 ------------------------------------
Mflv_5074|M.gilvum_PYR-GCK ------------------------------------
MSMEG_1403|M.smegmatis_MC2_155 ------------------------------------
TH_1889|M.thermoresistible__bu ------------------------------------