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LGAGAMTAGATLLGAPLPASAAPCPDIEVTFARGTAEPPGVGGVGQAFVEALRSQAGARSLGVYPVNYPA DDDFAASASAGAGDASAHVQSMVADCPNTKLVLGGYSQGAMVIDLITIAQAPVAGLIPQTLNADQAEHVS ALALFGNPSDRYLGAPVSVVSPWYGAKAIDLCAPGDPVCTPGGPLALPSHDEMVSPAHLSYRQSGMPAQA ATFVAAHL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1682 | - | - | 100% (219) | serine esterase, cutinase family protein |
| M. avium 104 | MAV_2741 | - | 4e-53 | 51.18% (211) | serine esterase, cutinase family protein |
| M. avium 104 | MAV_0369 | - | 3e-52 | 49.12% (228) | serine esterase cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2006c | cfp21 | 4e-53 | 51.63% (215) | cutinase precursor CFP21 |
| M. gilvum PYR-GCK | Mflv_3373 | - | 2e-47 | 47.96% (221) | cutinase |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 4e-53 | 51.63% (215) | cutinase precursor CFP21 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3766 | - | 8e-40 | 46.31% (203) | cutinase cut3 precursor |
| M. marinum M | MMAR_3837 | - | 1e-92 | 75.23% (222) | cutinase precursor |
| M. smegmatis MC2 155 | MSMEG_1528 | - | 1e-50 | 51.75% (228) | cutinase |
| M. thermoresistible (build 8) | TH_0238 | - | 1e-45 | 45.74% (223) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 4e-50 | 45.69% (232) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_3105 | - | 7e-52 | 50.92% (218) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3373|M.gilvum_PYR-GCK ------MRSKRLRAVAGAVFVATAASVQ-TVAGTP-----AAAADPCPDV
Mvan_3105|M.vanbaalenii_PYR-1 ------MQVRRVLGIVGAAVAVSAGLWP-IGVGAP-----AASADPCPDI
MSMEG_1528|M.smegmatis_MC2_155 --MSLDLVFRRARLVAAAALIATVMLAAPLAAHAPTGALGAARAADCPDI
MAB_3766|M.abscessus_ATCC_1997 --MTTHQRGTRVGVVLSSFVVLTVLVLSAASVVGPVSAVPRASADPCSDV
MAV_1682|M.avium_104 --------------MLGAG--AMTAGATLLGAPLP------ASAAPCPDI
MMAR_3837|M.marinum_M MCQHQNVNARQSTRLLGVG--LATICAALLSAPLII---ASASAAACPDA
Mb2006c|M.bovis_AF2122/97 ------MTPRSLVRIVGVVVATTLALVSAPAGGR------AAHADPCSDI
Rv1984c|M.tuberculosis_H37Rv ------MTPRSLVRIVGVVVATTLALVSAPAGGR------AAHADPCSDI
TH_0238|M.thermoresistible__bu ---LSRIGSAVGAALTTASLITGTVITSTVVAGTAV---PAAAAQPCPDV
MUL_4327|M.ulcerans_Agy99 ------MRNATWTRRLAVG--AATAVTALVGGGIRV---PFVAAEPCPDV
. * *.*
Mflv_3373|M.gilvum_PYR-GCK EVIWARGTGAPAGLGWLGTAFVDSLRAKVG--GRSVGAYGVNYPASFDFD
Mvan_3105|M.vanbaalenii_PYR-1 EVIFARGTGAEPGLGWVGDAFVNALRPKVG--GRSVGTYAVNYPAGFDFD
MSMEG_1528|M.smegmatis_MC2_155 EVVFARGTDESPGIGRIGNAFVQALRGKVG--GRSVGTYAVNYPASYDFL
MAB_3766|M.abscessus_ATCC_1997 DVSFARGRKEPVGLGRVGDEFVDSLTPRVQATGATMNVYPVNYDAG---I
MAV_1682|M.avium_104 EVTFARGTAEPPGVGGVGQAFVEALRSQAG--ARSLGVYPVNYPADDDFA
MMAR_3837|M.marinum_M EVTFARGTAEPPGVGGVGQAFIDSLRSQLG--GRSLGVYAVNYPATEDWP
Mb2006c|M.bovis_AF2122/97 AVVFARGTHQASGLGDVGEAFVDSLTSQVG--GRSIGVYAVNYPASDDYR
Rv1984c|M.tuberculosis_H37Rv AVVFARGTHQASGLGDVGEAFVDSLTSQVG--GRSIGVYAVNYPASDDYR
TH_0238|M.thermoresistible__bu QVVFARGTGEPPGVGPTGQAFIDALRPRVG--DRSLDVYAVNYPAIDVWN
MUL_4327|M.ulcerans_Agy99 EVLFARGTGEPPGIGGIGGSFVAALRSDIG--AKSSAVYAIDYPASSDFS
* :*** *:* * *: :* : .* ::* *
Mflv_3373|M.gilvum_PYR-GCK AS-----APMGAADAAGRVQWMADNCPDTRLVLGGNSQGAGVIDLITLDA
Mvan_3105|M.vanbaalenii_PYR-1 NS-----APLGAADASGRVQWMAGNCPDTKLVLGGMSQGAGVIDLITVDP
MSMEG_1528|M.smegmatis_MC2_155 AA-----AD-GANDASGHVQWMVNNCPNTRLVLGGYSQGAAVIDVIAAVP
MAB_3766|M.abscessus_ATCC_1997 FS-----AGGGANDLSNHLQSVAASCPRTKLVIGGYSMGAEVIDTIIGVP
MAV_1682|M.avium_104 AS-----ASAGAGDASAHVQSMVADCPNTKLVLGGYSQGAMVIDLITIAQ
MMAR_3837|M.marinum_M PS-----ASAGATDASTHVESMAASCPNTKLVLGGYSQGAMVIDLITIAR
Mb2006c|M.bovis_AF2122/97 AS-----ASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTSA-
Rv1984c|M.tuberculosis_H37Rv AS-----ASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTSA-
TH_0238|M.thermoresistible__bu TG------IDGIRDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAE
MUL_4327|M.ulcerans_Agy99 SSDFPRTVIDGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSAS
. * * . :: . .** *: *:** * ** * .
Mflv_3373|M.gilvum_PYR-GCK TP---RGRFTPTPLAPHLSDRVAAVAVFGNPLRDLP----GGGPLSQVSG
Mvan_3105|M.vanbaalenii_PYR-1 RP---LGRFTPTPMPPNVADHVAAVVVFGNPLRDIR----GGGPLPQMSG
MSMEG_1528|M.smegmatis_MC2_155 FP---AIGFN-APLPANVPEHVAAVAVFGNPSAKL------GLPLTASP-
MAB_3766|M.abscessus_ATCC_1997 NV---GIGFN-RPLPPTVGDRIVAIATFGNATHRT------GGPLSGIAG
MAV_1682|M.avium_104 AP---VAGLIPQTLNADQAEHVSALALFGNPSD-----RYLGAPVSVVSP
MMAR_3837|M.marinum_M AP---VAGFIPQTLSAEVADHVAAVAVFGNPTD-----RYLGGPISEISP
Mb2006c|M.bovis_AF2122/97 -------------MPPAVADHVAAVALFGEPSSGFSSMLWGGGSLPTIGP
Rv1984c|M.tuberculosis_H37Rv -------------MPPAVADHVAAVALFGEPSSGFSSMLWGGGSLPTIGP
TH_0238|M.thermoresistible__bu VPAGVDPATVPKPLDPDIAEHVAAVVLFGMPNA--RAMNFLGTPPVVIGP
MUL_4327|M.ulcerans_Agy99 VPPGVPAAAVPKPMAPDIADYVAAVTLFGTPSE--QFLQHYGAPPITIGP
: . : : *:. ** . * .
Mflv_3373|M.gilvum_PYR-GCK VFGSRSIDLCGLDDPFCSSGLN----------FPAHFSYIKNG-MVEEAT
Mvan_3105|M.vanbaalenii_PYR-1 TYGSKSIDLCAFDDPFCSPGFN----------LPAHFAYVDNG-MVEEAA
MSMEG_1528|M.smegmatis_MC2_155 VYGSRAIDLCNAGDPVCGSGDS----------VPAHRAY-DGG-PANQAA
MAB_3766|M.abscessus_ATCC_1997 VFGSRAIDLCNQGDPICMAGPNN--------SWDAHTSYERTG-LPAEAA
MAV_1682|M.avium_104 WYGAKAIDLCAPGDPVCTPGGPLALPSHDEMVSPAHLSYRQSG-MPAQAA
MMAR_3837|M.marinum_M WYGHKAIDLCAPNDPICTPG-ALALPSHDEMFSAAHLSYAQSG-MPSQAA
Mb2006c|M.bovis_AF2122/97 LYSSKTINLCAPDDPICTGG----------GNIMAHVSYVQSG-MTSQAA
Rv1984c|M.tuberculosis_H37Rv LYSSKTINLCAPDDPICTGG----------GNIMAHVSYVQSG-MTSQAA
TH_0238|M.thermoresistible__bu LYEDKTVKLCAVDDPVCSNG----------MNFAAHNTYATNAAMVDQGA
MUL_4327|M.ulcerans_Agy99 LYQPRTIELCASGDPVCSGG----------NDAAAHALYAVNG-MTGQGA
: :::.** .**.* * ** * . :.:
Mflv_3373|M.gilvum_PYR-GCK NFVAGRLQ------------------
Mvan_3105|M.vanbaalenii_PYR-1 NFAAGRLG------------------
MSMEG_1528|M.smegmatis_MC2_155 AFVAGLL-------------------
MAB_3766|M.abscessus_ATCC_1997 AFVASKLNRHGESEAE----------
MAV_1682|M.avium_104 TFVAAHL-------------------
MMAR_3837|M.marinum_M TFVVSQL-------------------
Mb2006c|M.bovis_AF2122/97 TFAANRLDHAG---------------
Rv1984c|M.tuberculosis_H37Rv TFAANRLDHAG---------------
TH_0238|M.thermoresistible__bu AFAADRLGVASDKPLPTPSSGQNFGN
MUL_4327|M.ulcerans_Agy99 DFAAHHL-------------------
*.. *