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LTALLEARGISRSFGHVRALDGADFDIDAGEVVGLIGDNGAGKSTLIKALSGSLELDDGEILFEGKPVHL ATPRDANDLGIEVVYQDLALAPHLNPVQNVFLGREIPRPGLLGRFGFMDEKTMRKQAAASFAELGATVRS LSAPVGSMSGGQRQSIAIARAIAWADKVVILDEPTAALGVVQTKNVLETVKRVRDKGIAVIFISHSMPHV LEVCDRIQVLRLGRRVATYPGQGTSVETLVGAMTGALDGRAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1372 | - | - | 100% (252) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6802 | - | 3e-64 | 49.59% (246) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6019 | - | 2e-58 | 48.59% (249) | ABC-type sugar transport system ATPase component |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 2e-22 | 31.06% (235) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_2607 | - | 7e-47 | 40.74% (243) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 2e-22 | 31.06% (235) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00336 | - | 9e-20 | 29.46% (224) | putative ABC-tranporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2623c | - | 6e-31 | 31.91% (257) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_0060 | - | 6e-24 | 31.86% (226) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 2e-22 | 30.53% (226) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_3313 | - | 3e-28 | 32.62% (233) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-22 | 32.02% (228) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_5292 | - | 5e-60 | 48.59% (249) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 --------------------------------MT--------YAIVVADA
Rv2397c|M.tuberculosis_H37Rv --------------------------------MT--------YAIVVADA
MUL_3658|M.ulcerans_Agy99 --------------------------------MTGPGTG--GHAIVVRDA
MMAR_0060|M.marinum_M --------------------------------MTRQDAGRQPVCLAARSI
MAV_0058|M.avium_104 --------------------------------MS-NPASRASVSLACKDI
MSMEG_1372|M.smegmatis_MC2_155 ------------------------------------MT----ALLEARGI
Mvan_5292|M.vanbaalenii_PYR-1 -----------------------MD----------TQP----PILELRGV
Mflv_2607|M.gilvum_PYR-GCK --------------MTISVEKASSD----------SKPGGKVPLVELKNI
MAB_2623c|M.abscessus_ATCC_199 MTKHRDSSLDDEQDSVEMLQAEIEEGSDEGESGVPVDPGEAEVLLEVKDL
TH_3313|M.thermoresistible__bu -------------MSIEELAGVHRD----------IRAAEGEILLETVDL
MLBr_00336|M.leprae_Br4923 -------------MAVENLDAVSRR---------PQSADNDARTISLSGA
: .
Mb2419c|M.bovis_AF2122/97 TKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
Rv2397c|M.tuberculosis_H37Rv TKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGT
MUL_3658|M.ulcerans_Agy99 FKQYGDFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGN
MMAR_0060|M.marinum_M HQTLGGSVVLRGVDLEVPAGTTAAVIGPSGSGKSTLLRTLNRLHEPDSGD
MAV_0058|M.avium_104 HQTLNGNAVLRGVDLDTPAGSTVAVIGPSGSGKSTLLRTLNRLYEPDRGD
MSMEG_1372|M.smegmatis_MC2_155 SRSFGHVRALDGADFDIDAGEVVGLIGDNGAGKSTLIKALSGSLELDDGE
Mvan_5292|M.vanbaalenii_PYR-1 NKSFGVVHVLHDVDFCVYPGQVTALVGDNGAGKSTLVKAIAGIHPIDTGT
Mflv_2607|M.gilvum_PYR-GCK GKSYGNITALKDISLRVHAGEVTGILGDNGAGKSTLIKIIAGLHQQTDGE
MAB_2623c|M.abscessus_ATCC_199 TLKFGGLQALDGVSFDIRRGEILGLVGPNGAGKTTCFNAITGVYKPTSGS
TH_3313|M.thermoresistible__bu TVKFGGLVALDSVSFNIRRGEILGLIGPNGAGKTTCFNAITGVYRPASGA
MLBr_00336|M.leprae_Br4923 RLAFGDQTLWDHLDLSVSAGEFIAVLGPNGTGKTSLLKVLLGQLELSAGV
. .: * .::* .*:**:: .. : *
Mb2419c|M.bovis_AF2122/97 ITINGRDVTRVPPQ---RRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRK-
Rv2397c|M.tuberculosis_H37Rv ITINGRDVTRVPPQ---RRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRK-
MUL_3658|M.ulcerans_Agy99 ITINGRDVTRVPPQ---RRGIGFVFQHYAAFKHLTVRDNVAYG-LKIRK-
MMAR_0060|M.marinum_M ILLDGRSVLRDNPNDL-RQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRG-
MAV_0058|M.avium_104 ILLDGRSVLHDDPDQL-RQRIGMVFQHFNLFPHRTVLDNVALAPRKLRR-
MSMEG_1372|M.smegmatis_MC2_155 ILFEGKPVHLATPRDANDLGIEVVYQDLALAPHLNPVQNVFLG-REIPRP
Mvan_5292|M.vanbaalenii_PYR-1 YLFEGKPVTVHSPNDVSALGVEVVYQDLALCDNLDIVENMFLG-RELKRR
Mflv_2607|M.gilvum_PYR-GCK LLVDGEPTRFASPADALGKGIATVYQNLAVVPLMPVWRNFFLG-QELRKK
MAB_2623c|M.abscessus_ATCC_199 IVFNGKPLRRLRRHQITRRGIARTFQNIRLFGEMTALENVAVG-TDARHK
TH_3313|M.thermoresistible__bu VIFDGQKLGRIKRHQITRLGIARTFQNIRLWGEMTALENVVVG-TDARHK
MLBr_00336|M.leprae_Br4923 ARVEGKRITAGSPR----IGYVPQHRPIDREVLLRGRDLVRLGIDGRRWG
.:*. .: . .
Mb2419c|M.bovis_AF2122/97 --------RPKAEIKAKVDNLLQVVGLS------GFQSRYPNQLSGGQRQ
Rv2397c|M.tuberculosis_H37Rv --------RPKAEIKAKVDNLLQVVGLS------GFQSRYPNQLSGGQRQ
MUL_3658|M.ulcerans_Agy99 --------RPKAEIRDKVDNLLEVVGLS------GFHGRYPDQLSGGQRQ
MMAR_0060|M.marinum_M --------LSNEEARMLALDQLDRVGLK------HKANARPDMLSGGQQQ
MAV_0058|M.avium_104 --------LPAEAARELALTQLDRVGLK------HKAGARPATLSGGQQQ
MSMEG_1372|M.smegmatis_MC2_155 GLLGRFGFMDEKTMRKQAAASFAELGA-----TVRSLSAPVGSMSGGQRQ
Mvan_5292|M.vanbaalenii_PYR-1 GML------DEARMETMAREALTSLSVR----TVKSVRQPVSSLSGGQRQ
Mflv_2607|M.gilvum_PYR-GCK RFPFS---LDANAMRATTLTELAKMGI-----DLPDVDVPIGSLSGGQKQ
MAB_2623c|M.abscessus_ATCC_199 TSVLGALLRTPRHRREEHYAVDVGMGLLDFVGIADDADVKAKNLPYGSQR
TH_3313|M.thermoresistible__bu TSVPGALFRSPRHRREERSAIERATALLHFVGIAHRAEEKAKNLPYGDQR
MLBr_00336|M.leprae_Br4923 ALPLR--SADRARRREAVFTALQQVNGE------QLADVRVGVMSGGELQ
. :. *. :
Mb2419c|M.bovis_AF2122/97 RMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLV
Rv2397c|M.tuberculosis_H37Rv RMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLV
MUL_3658|M.ulcerans_Agy99 RMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLV
MMAR_0060|M.marinum_M RVAIARALAMAPQVMFFDEATSALDPEMVKGILALIADLGADG-MTMVVV
MAV_0058|M.avium_104 RVAIARALAMSPQVMFFDEATSALDPEMVKGILQLIADLGAEG-MTMVVV
MSMEG_1372|M.smegmatis_MC2_155 SIAIARAIAWADKVVILDEPTAALGVVQTKNVLETVKRVRDKG-IAVIFI
Mvan_5292|M.vanbaalenii_PYR-1 TVAIAKSVLWNSKVVLLDEPTAALGVAQTRQVIELVRGLAERG-VGVVLI
Mflv_2607|M.gilvum_PYR-GCK CVAIARAVFFGARVLILDEPTAALGVKQSGVVLKYITAAKEAG-FGVVFI
MAB_2623c|M.abscessus_ATCC_199 RLEIARALATEPKLLCLDEPAAGFTPSEKDSLIELIQRIRDYG-YTVLLI
TH_3313|M.thermoresistible__bu RLEIARALATEPKLLCLDEPAAGFNPSEKAALIDLIRKIRDDG-YTVLLI
MLBr_00336|M.leprae_Br4923 RIRIAQALVNDPTLLLCDEPLLTLDPANAKLVSTLIDRRRREAGTTVLVV
: :*::: :: **. : : : :.:
Mb2419c|M.bovis_AF2122/97 THDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTL
Rv2397c|M.tuberculosis_H37Rv THDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVSTL
MUL_3658|M.ulcerans_Agy99 THDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFLGAVSAL
MMAR_0060|M.marinum_M THEMGFARSTSDAVVFMDHGTVVEAGPPEQLFEAARTERLQRFLAQVL--
MAV_0058|M.avium_104 THEMGFARSASDAVIFMDHGKVVESGPPEQIFEAAETERLQRFLSQVL--
MSMEG_1372|M.smegmatis_MC2_155 SHSMPHVLEVCDRIQVLRLGRRVATYPG----QGTSVETLVGA---MTGA
Mvan_5292|M.vanbaalenii_PYR-1 SHNMNDVFEVADRICALYLGRVAAEVKASEVSHGQVVELITAG---RSGS
Mflv_2607|M.gilvum_PYR-GCK THNPHHAHLVGDHFVLLNRGRQKLDCSYDDITLEHLTQQMAGGDELEALS
MAB_2623c|M.abscessus_ATCC_199 EHDMKLVMGVTDRIVVLEFGRKIADGLPAEVRNDPAVIEAYLGVADEDFH
TH_3313|M.thermoresistible__bu EHDMKLVMGVTDRIVVLEFGRKIADGPPAAIREDPAVIAAYLGVPDDEIG
MLBr_00336|M.leprae_Br4923 THEINPLLPYVDRVLYLVDGRFLIGTVEQVMTTERLSTLYQANIRVVKVE
*. * . : *
Mb2419c|M.bovis_AF2122/97 NGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVE
Rv2397c|M.tuberculosis_H37Rv NGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVE
MUL_3658|M.ulcerans_Agy99 NGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVE
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MSMEG_1372|M.smegmatis_MC2_155 LDGRAA--------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 LGLAPAQAAESM--------------------------------------
Mflv_2607|M.gilvum_PYR-GCK HELRAAKQ------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 GPGWLDSAPPDSESER----------------------------------
TH_3313|M.thermoresistible__bu --------------------------------------------------
MLBr_00336|M.leprae_Br4923 DHYIVVGEP-----------------------------------------
Mb2419c|M.bovis_AF2122/97 LTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDA
Rv2397c|M.tuberculosis_H37Rv LTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDA
MUL_3658|M.ulcerans_Agy99 LTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDD
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MSMEG_1372|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3313|M.thermoresistible__bu --------------------------------------------------
MLBr_00336|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 GVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv GVERVKVTST------
MUL_3658|M.ulcerans_Agy99 GAGSTPRAAQIGVGGQ
MMAR_0060|M.marinum_M ----------------
MAV_0058|M.avium_104 ----------------
MSMEG_1372|M.smegmatis_MC2_155 ----------------
Mvan_5292|M.vanbaalenii_PYR-1 ----------------
Mflv_2607|M.gilvum_PYR-GCK ----------------
MAB_2623c|M.abscessus_ATCC_199 ----------------
TH_3313|M.thermoresistible__bu ----------------
MLBr_00336|M.leprae_Br4923 ----------------