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AVENLDAVSRRPQSADNDARTISLSGARLAFGDQTLWDHLDLSVSAGEFIAVLGPNGTGKTSLLKVLLGQ LELSAGVARVEGKRITAGSPRIGYVPQHRPIDREVLLRGRDLVRLGIDGRRWGALPLRSADRARRREAVF TALQQVNGEQLADVRVGVMSGGELQRIRIAQALVNDPTLLLCDEPLLTLDPANAKLVSTLIDRRRREAGT TVLVVTHEINPLLPYVDRVLYLVDGRFLIGTVEQVMTTERLSTLYQANIRVVKVEDHYIVVGEP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00336 | - | - | 100% (275) | putative ABC-tranporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01726 | - | 2e-21 | 33.88% (242) | putative ABC transporter protein, ATP-binding component |
| M. leprae Br4923 | MLBr_01892 | - | 4e-20 | 32.18% (202) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1890 | modC | 1e-25 | 36.77% (223) | molybdenum ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_1455 | - | 2e-46 | 40.73% (248) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1859 | modC | 1e-25 | 36.77% (223) | molybdenum ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_0576c | - | 8e-78 | 60.16% (251) | putative ABC transporter ATP-binding protein |
| M. marinum M | MMAR_5072 | - | 1e-105 | 75.49% (257) | ATPase component of an ABC-type transport system |
| M. avium 104 | MAV_0582 | - | 1e-112 | 76.54% (260) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6046 | - | 3e-36 | 36.09% (230) | cation ABC transporter, ATP-binding protein, putative |
| M. thermoresistible (build 8) | TH_3585 | - | 6e-93 | 69.44% (252) | PUTATIVE ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_4148 | - | 1e-105 | 75.49% (257) | ATPase component of an ABC-type transport system |
| M. vanbaalenii PYR-1 | Mvan_5319 | - | 1e-45 | 41.74% (230) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00336|M.leprae_Br4923 MAVENLDAVSRRPQSADNDARTISLSGARLAFGDQTLWDHLDLSVSAGEF
MAV_0582|M.avium_104 MSLQAAAAV-------DHDADTVSLRGARLAFGDRVLWEDLDLSVSRGEF
MMAR_5072|M.marinum_M MNQSNHPAI--------------ALRGARLAFGDRVLWEDLDLSVSRGEF
MUL_4148|M.ulcerans_Agy99 MNQSNHPAI--------------ALRGARLAFGDRVLWEDLDLSVSRGEF
TH_3585|M.thermoresistible__bu VSSDPHAVV--------------SLRGARLAFGDRVLWDGLDLTVRAGEF
MAB_0576c|M.abscessus_ATCC_199 MSAA-------------------TLRDASLNRGGRTLWQGLDLTVEPGEF
Mflv_1455|M.gilvum_PYR-GCK MSAP---EPATA----------LSFTDVSAERGGRIIWSESTFDVEAGRF
Mvan_5319|M.vanbaalenii_PYR-1 MSGPESVEAAPA----------LTFDDVSVDRGGRTIWSESTFRVDAGSF
MSMEG_6046|M.smegmatis_MC2_155 MSSHN-AETEPA----------LVFDDVSVVRGGRLIWSEGTFTIPSGGI
Mb1890|M.bovis_AF2122/97 ------------------------MSKLQLRAVVADRRLDVEFSVSAGEV
Rv1859|M.tuberculosis_H37Rv ------------------------MSKLQLRAVVADRRLDVEFSVSAGEV
: : : * .
MLBr_00336|M.leprae_Br4923 IAVLGPNGTGKTSLLKVLLGQLELSAGVARVEGKRITAGSPR---IGYVP
MAV_0582|M.avium_104 VAVLGPNGSGKTSLLKVLLGQLPLSAGVGLVDGKPITSGSGR---IGYVP
MMAR_5072|M.marinum_M IAVLGPNGTGKTSLLKVLLGELALSAGVALVDGARLDTGRTRRGHIGYVP
MUL_4148|M.ulcerans_Agy99 IAVLGPNGTGKTSLLKVLLGELALSAGVALVDGARLDTGRTRRGHIGYVP
TH_3585|M.thermoresistible__bu IAVLGPNGTGKTSLLKVLLGQLPLSAGQARVLGRPVGAGNRH---VGYVP
MAB_0576c|M.abscessus_ATCC_199 IAVLGPNGSGKTSLLRLLLGQVPLTRGSMTVTSD-----------LGYVP
Mflv_1455|M.gilvum_PYR-GCK VAVIGPNGSGKTTLLQVILGLLGPASGSVRVFGRAPGTQNDE---IGYVP
Mvan_5319|M.vanbaalenii_PYR-1 VAIIGPNGSGKTTLLQVILGLLPPSSGTVRVYGRQPGAANDE---IGYVP
MSMEG_6046|M.smegmatis_MC2_155 VALIGSNGSGKSTMLQVILGLLPVASGSVRVLDGRPGEHNDQ---IGYVP
Mb1890|M.bovis_AF2122/97 LAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLTDTEAGVNVATHDR
Rv1859|M.tuberculosis_H37Rv LAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLTDTEAGVNVATHDR
:*::*.**:**:: *::: * : * : . :
MLBr_00336|M.leprae_Br4923 QHRPIDREVLLRGRDLVRLGIDGRRWGALPLRSADRARRREAVFTALQQV
MAV_0582|M.avium_104 QHRPMERDVMLRGRDLVRLGLDGGRWGAAPLRPRERARRRATVDQALRQV
MMAR_5072|M.marinum_M QHHPIDREVMLRGRDLVGLGVDGCRWGAVALRSGERARRREAVQRALQQV
MUL_4148|M.ulcerans_Agy99 QHHPIDREVMLRGRDLVGLGVDGCRWGAVALRSGERARRREAVQRALQQV
TH_3585|M.thermoresistible__bu QHRSLDSGLTLRGRDLVGLGYDGHRWGLPDPRG--RDAKRTAVRQALQQV
MAB_0576c|M.abscessus_ATCC_199 QHRLADNALILRAEDLVGLGIDGHRWGLASFNPARRARYRAAVDLALNQV
Mflv_1455|M.gilvum_PYR-GCK QNYDANANEAIRARDAVLLGLTGRRWGFGRTSAADRAR----VEEALGWV
Mvan_5319|M.vanbaalenii_PYR-1 QNYDANANEAIRASDAVLLGLTGRRWGFGRTSTADRRR----VDEALGWV
MSMEG_6046|M.smegmatis_MC2_155 QDYVAGAGEAIRARDAVTLGLTGHRWGMRRVTAEEKAR----VDQALAAV
Mb1890|M.bovis_AF2122/97 RVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREV
Rv1859|M.tuberculosis_H37Rv RVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREV
: : * . : . * *
MLBr_00336|M.leprae_Br4923 NGEQLADVRVGVMSGGELQRIRIAQALVNDPTLLLCDEPLLTLDPANAKL
MAV_0582|M.avium_104 NGEHLADVRAGVMSGGELQRMRVAQALVSDPLLLLCDEPLLTLDPANAKL
MMAR_5072|M.marinum_M DGERLADVRVGLMSGGELQRIRVAQALASDPSLLLCDEPLLALDPANANL
MUL_4148|M.ulcerans_Agy99 GGERLADVRVGLMSGGELQRIRVAQALASDPSLLLCDEPLLALDPANANL
TH_3585|M.thermoresistible__bu NADHLADTPVGLMSGGELQRVRIAQALVTDPELLLCDEPLLNLDPGHARL
MAB_0576c|M.abscessus_ATCC_199 DASHLATKAVSSLSGGELQRVRIAQALAGDPALLLCDEPLLNLDPASAQQ
Mflv_1455|M.gilvum_PYR-GCK DAVGIADRRLSDLSGGQRQRIALAGALVAQPKMLILDEPLASLDVRNQHE
Mvan_5319|M.vanbaalenii_PYR-1 DALDIADRRLSDLSGGQRQRIALAGALVARPRMLILDEPLASLDLRNQHE
MSMEG_6046|M.smegmatis_MC2_155 EATEFADRRVSQLSGGQRQRIALANALVAHPRMLILDEPLAALDLRSQHE
Mb1890|M.bovis_AF2122/97 NAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAG
Rv1859|M.tuberculosis_H37Rv NAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAG
. :* :***: **: :* **. * :*: **** **
MLBr_00336|M.leprae_Br4923 VSTLIDRRRREAGTTVLVVTHEINPLLPYVDRVLYLVDG-RFLIGTVEQV
MAV_0582|M.avium_104 VSALLERRRRDAATTVIVVTHEINPILPYVDRVLYLVDG-RFRIGTVEQV
MMAR_5072|M.marinum_M VAALLDRRRREAATAVMVVTHEVNPILPYVDRVLYLVDG-RFLIGTVEQV
MUL_4148|M.ulcerans_Agy99 VAALLDRRRREAATAVMVVTHEVNPILPYVDRVLYLVDG-RFLIGTVEQV
TH_3585|M.thermoresistible__bu VAALIDRRRRTADTAVLFVTHEVNPVLRYVDRVLYLVDG-QFRIGTVEEV
MAB_0576c|M.abscessus_ATCC_199 ICALIDKRRCDAQTAVLFVTHEINPIVPYVDRILYLVDG-RFQIGTVDEV
Mflv_1455|M.gilvum_PYR-GCK IVAVLGRLKRELGVTVLVVAHDLNPLLGVLDSAIYLLDG-HAHHAALDKV
Mvan_5319|M.vanbaalenii_PYR-1 IVAVLARLKRDLGVTVLVVAHDLNPLLTVLDSAIYLLDG-HAHHAALDRV
MSMEG_6046|M.smegmatis_MC2_155 IVQLLARVNSEYQVTIIVVAHDLNPLLSVLDSAIYLLDG-HAHHAPMD-V
Mb1890|M.bovis_AF2122/97 IRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADV
Rv1859|M.tuberculosis_H37Rv IRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADV
: :: :::..:*:: :. * : * .* ..: *
MLBr_00336|M.leprae_Br4923 MTTER---------------------------LSTLYQANIRVVKVEDH-
MAV_0582|M.avium_104 MNSET---------------------------LSALYRADIQVVKVKGG-
MMAR_5072|M.marinum_M MTSQT---------------------------LSTLYRADIEVIKVVKGP
MUL_4148|M.ulcerans_Agy99 MTSQT---------------------------LSTLYRADIEVIKVVKGP
TH_3585|M.thermoresistible__bu MTSET---------------------------LSELYGADIEVLRVGGR-
MAB_0576c|M.abscessus_ATCC_199 MTTET---------------------------LSELYRAQIDVVKIRGQ-
Mflv_1455|M.gilvum_PYR-GCK VDSAL---------------------------LTHMYGTRIQVAHTLQG-
Mvan_5319|M.vanbaalenii_PYR-1 VDSQL---------------------------LTHMYGTRIQVAHTLQG-
MSMEG_6046|M.smegmatis_MC2_155 VNADL---------------------------LTHLYGTKVQVANTLQG-
Mb1890|M.bovis_AF2122/97 LTAPRSRFGARIAGVNLVNGTIGPDGSLRTQSGAHWYGTPVQDLPTGHEA
Rv1859|M.tuberculosis_H37Rv LTAPRSRFGARIAGVNLVNGTIGPDGSLRTQSGAHWYGTPVQDLPTGHEA
: : : * : :
MLBr_00336|M.leprae_Br4923 ---YIVVGEP----------------------------------------
MAV_0582|M.avium_104 ---YVVAGEHTDGHG-----------------------------------
MMAR_5072|M.marinum_M HTRYLVVDAQDGLR------------------------------------
MUL_4148|M.ulcerans_Agy99 HTRYLVVDAQDGLR------------------------------------
TH_3585|M.thermoresistible__bu ---YVVVGEHLDHSGHMSGHLHE---------------------------
MAB_0576c|M.abscessus_ATCC_199 ---YVVVGEDRQITAECAEHAHE---------------------------
Mflv_1455|M.gilvum_PYR-GCK -ELYMRSGG-----------------------------------------
Mvan_5319|M.vanbaalenii_PYR-1 -ELYMRSGG-----------------------------------------
MSMEG_6046|M.smegmatis_MC2_155 -QMYMRSE------------------------------------------
Mb1890|M.bovis_AF2122/97 IAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPMVLVRGHDQPGGAP
Rv1859|M.tuberculosis_H37Rv IAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPTVLVRGHDQPGGAP
:
MLBr_00336|M.leprae_Br4923 -------------------------------------------
MAV_0582|M.avium_104 -------------------------------------------
MMAR_5072|M.marinum_M -------------------------------------------
MUL_4148|M.ulcerans_Agy99 -------------------------------------------
TH_3585|M.thermoresistible__bu -------------------------------------------
MAB_0576c|M.abscessus_ATCC_199 -------------------------------------------
Mflv_1455|M.gilvum_PYR-GCK -------------------------------------------
Mvan_5319|M.vanbaalenii_PYR-1 -------------------------------------------
MSMEG_6046|M.smegmatis_MC2_155 -------------------------------------------
Mb1890|M.bovis_AF2122/97 GLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS
Rv1859|M.tuberculosis_H37Rv GLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS