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DTQPPILELRGVNKSFGVVHVLHDVDFCVYPGQVTALVGDNGAGKSTLVKAIAGIHPIDTGTYLFEGKPV TVHSPNDVSALGVEVVYQDLALCDNLDIVENMFLGRELKRRGMLDEARMETMAREALTSLSVRTVKSVRQ PVSSLSGGQRQTVAIAKSVLWNSKVVLLDEPTAALGVAQTRQVIELVRGLAERGVGVVLISHNMNDVFEV ADRICALYLGRVAAEVKASEVSHGQVVELITAGRSGSLGLAPAQAAESM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5292 | - | - | 100% (260) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4009 | - | 1e-43 | 38.71% (248) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2428 | - | 8e-29 | 33.04% (224) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 2e-25 | 35.24% (210) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_2607 | - | 1e-43 | 37.76% (241) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 2e-25 | 35.24% (210) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00590 | - | 1e-19 | 27.92% (240) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4237c | - | 9e-28 | 31.78% (236) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0922 | - | 4e-25 | 33.48% (230) | ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_1785 | - | 3e-24 | 33.63% (226) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_6019 | - | 1e-127 | 89.53% (258) | ABC-type sugar transport system ATPase component |
| M. thermoresistible (build 8) | TH_1784 | - | 2e-30 | 33.78% (225) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_0674 | - | 6e-25 | 33.48% (230) | ABC transporter, ATP-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0922|M.marinum_M -------MTRAQAPTSPRGGVSLHGVDKTFGTAAASVHALRGIDLDIEPG
MUL_0674|M.ulcerans_Agy99 -------MTRAQAPTSPRGGVSLHGVDKTFGTAAASVHALRRIDLDIEPG
Mb2419c|M.bovis_AF2122/97 --------MT--------YAIVVADATKRYG----DFVALDHVDFVVPTG
Rv2397c|M.tuberculosis_H37Rv --------MT--------YAIVVADATKRYG----DFVALDHVDFVVPTG
MAV_1785|M.avium_104 --------MTDAGTDRGDIAITVRDAYKRYG----DFVALDHVDFVVPTG
MAB_4237c|M.abscessus_ATCC_199 -----------------MSTIEVRGVRKSYG----QVTALRDVNLTVHQG
TH_1784|M.thermoresistible__bu MDSAGADVAVADPAAEAVPMISMRGVNKYFG----SLHVLRDINLDVARG
Mvan_5292|M.vanbaalenii_PYR-1 ---------MDTQP----PILELRGVNKSFG----VVHVLHDVDFCVYPG
MSMEG_6019|M.smegmatis_MC2_155 ----------MTPE----PILELQRVNKSFG----VVHVLHDVDFRVYPG
Mflv_2607|M.gilvum_PYR-GCK MTISVEKASSDSKPGGKVPLVELKNIGKSYG----NITALKDISLRVHAG
MLBr_00590|M.leprae_Br4923 ------MSSACTVPETPEVVIRLRGVCKHYG----SILAVSNLDLDIHSA
: : * :* . .: :.: : .
MMAR_0922|M.marinum_M ELVAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPR------
MUL_0674|M.ulcerans_Agy99 ELVAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPR------
Mb2419c|M.bovis_AF2122/97 SLTALLGPSGSGKSTLLRTIAGLDQPDTGTITING-------RD------
Rv2397c|M.tuberculosis_H37Rv SLTALLGPSGSGKSTLLRTIAGLDQPDTGTITING-------RD------
MAV_1785|M.avium_104 SLTALLGPSGSGKSTLLRTIAGLDQPDTGTVTIYG-------RD------
MAB_4237c|M.abscessus_ATCC_199 EVTVIIGPSGSGKSTLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYEL
TH_1784|M.thermoresistible__bu QVVVVLGPSGSGKSTLCRTLNRLEPIDSGAISIDG--VALPAEG------
Mvan_5292|M.vanbaalenii_PYR-1 QVTALVGDNGAGKSTLVKAIAGIHPIDTGTYLFEGKPVTVHSPN------
MSMEG_6019|M.smegmatis_MC2_155 QVTALVGDNGAGKSTLVKAIAGIHPIDSGTYLFEGKPVTVRTPN------
Mflv_2607|M.gilvum_PYR-GCK EVTGILGDNGAGKSTLIKIIAGLHQQTDGELLVDGEPTRFASPA------
MLBr_00590|M.leprae_Br4923 EVLALLGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNAR------
.: ::* .*:**:* . : * . *
MMAR_0922|M.marinum_M --ALSKFRRDHVGFIFQFFNLIPTLTAKENVEVIVELTGRGDRR----RA
MUL_0674|M.ulcerans_Agy99 --ALSKFRRDHVGFIFQFFNLIPTLTAKENVEVIVELTGRGDRR----RA
Mb2419c|M.bovis_AF2122/97 -VTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKV
Rv2397c|M.tuberculosis_H37Rv -VTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKV
MAV_1785|M.avium_104 -VTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYG-LKVRKRPKAEIKAKV
MAB_4237c|M.abscessus_ATCC_199 PERAILRQRSQVGFVFQNFNLFPHLTVLENVIEAPLAARRAPRAELEAEA
TH_1784|M.thermoresistible__bu --RELARLRADVGMVFQQFNLFAHKTIVDNVALGPMKVRKTPREQARAEA
Mvan_5292|M.vanbaalenii_PYR-1 -----DVSALGVEVVYQDLALCDNLDIVENMFLGRELKRRGMLDEARMET
MSMEG_6019|M.smegmatis_MC2_155 -----DVSALGIEVVYQDLALCDNLDIVENMFLGREIKVRGMLDEARMET
Mflv_2607|M.gilvum_PYR-GCK -----DALGKGIATVYQNLAVVPLMPVWRNFFLGQELRKKRFPFSLDANA
MLBr_00590|M.leprae_Br4923 -------LRARIGVMLQGGGGYPAARAGEMLNLVASYAADPLDPEWLLET
: : * . ..
MMAR_0922|M.marinum_M TELLDAVGLADR------AGSFPGQLSGGQQQRVAIARALITDPDLLLAD
MUL_0674|M.ulcerans_Agy99 TELLDAVELADR------AGSFPGQLSGGQQQRVAIARALITNPDLLLAD
Mb2419c|M.bovis_AF2122/97 DNLLQVVGLSGF------QSRYPNQLSGGQRQRMALARALAVDPEVLLLD
Rv2397c|M.tuberculosis_H37Rv DNLLQVVGLSGF------QSRYPNQLSGGQRQRMALARALAVDPEVLLLD
MAV_1785|M.avium_104 DNLLEVVGLSGF------QGRYPNQLSGGQRQRMALARALAVDPQVLLLD
MAB_4237c|M.abscessus_ATCC_199 TRLLERVGVADK------AAQYPRRLSGGQQQRVAIARALALRPKVILFD
TH_1784|M.thermoresistible__bu MALLERVGVADQ------ADKYPAQLSGGQQQRVAIARSLAMNPKVMLFD
Mvan_5292|M.vanbaalenii_PYR-1 MAREALTSLSVR--TVKSVRQPVSSLSGGQRQTVAIAKSVLWNSKVVLLD
MSMEG_6019|M.smegmatis_MC2_155 MARDALKSLSVR--TVNSVRQPVSSLSGGQRQTVAIAKSVLWNSKVVLLD
Mflv_2607|M.gilvum_PYR-GCK MRATTLTELAKMGIDLPDVDVPIGSLSGGQKQCVAIARAVFFGARVLILD
MLBr_00590|M.leprae_Br4923 LGLTDVARTTYR------------RLSGGQQQRLALACTLVGRPELVFLD
: *****:* :*:* :: . ::: *
MMAR_0922|M.marinum_M EPMGALDVATGRRVLELLQQTNRSG-LGVIMVTHNR-AAADVADRIIQMR
MUL_0674|M.ulcerans_Agy99 EPMGALDVATGRRVLELLQQTNRSG-LGVIMVTHNR-AAADVADPIIQMR
Mb2419c|M.bovis_AF2122/97 EPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLH
Rv2397c|M.tuberculosis_H37Rv EPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLH
MAV_1785|M.avium_104 EPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLN
MAB_4237c|M.abscessus_ATCC_199 EPTSALDPELVTEVLDVIAQLARDG-ATLVIVTHEIGLAREIADTVVFMD
TH_1784|M.thermoresistible__bu EPTSALDPEMINEVLAVMSALAADG-MTMLVVTHEMGFARRASDRVVFMS
Mvan_5292|M.vanbaalenii_PYR-1 EPTAALGVAQTRQVIELVRGLAERG-VGVVLISHNMNDVFEVADRICALY
MSMEG_6019|M.smegmatis_MC2_155 EPTAALGVAQTRQVIDLVRRLAGQG-LGVVLISHNMNDVFDVADRICALY
Mflv_2607|M.gilvum_PYR-GCK EPTAALGVKQSGVVLKYITAAKEAG-FGVVFITHNPHHAHLVGDHFVLLN
MLBr_00590|M.leprae_Br4923 EPTAGMDTHARLLVWELIDTLRRDG-VTVVLTTHQLKEAEELADRLVIID
** ..:. : : :. :*: . .* . :
MMAR_0922|M.marinum_M DGAIVEQRRNSAPAEASSVRW-----------------------------
MUL_0674|M.ulcerans_Agy99 DGAIVEQRRNSAPAEASSVRW-----------------------------
Mb2419c|M.bovis_AF2122/97 KGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNM
Rv2397c|M.tuberculosis_H37Rv KGRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNM
MAV_1785|M.avium_104 QGRIEQIGSPTEVYDAPTNAFVMSFLGAVSTLNGTLVRPHDIRVGRTPEM
MAB_4237c|M.abscessus_ATCC_199 RGAIVEQGPPKEVLDSPSHPRTASFLSKVLS-------------------
TH_1784|M.thermoresistible__bu DGAIVEDAEPARFFEDPQTDRARDFLGKILHH------------------
Mvan_5292|M.vanbaalenii_PYR-1 LGRVAAEVKASEVSHGQVVELITAGRSGSLGLAPAQAAESM---------
MSMEG_6019|M.smegmatis_MC2_155 LGRVAADVPAADVTHGQVVELITAGRSGNLGLAPAEAAESM---------
Mflv_2607|M.gilvum_PYR-GCK RGRQKLDCSYDDITLEHLTQQMAGGDELEALSHELRAAKQ----------
MLBr_00590|M.leprae_Br4923 HGRMIAAGTPTELMHTGAKDQLRFSAPPRLDLSLLAFALPEDYKTTELTP
*
MMAR_0922|M.marinum_M --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 AVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGD
Rv2397c|M.tuberculosis_H37Rv AVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGD
MAV_1785|M.avium_104 AVAAEDGTAESTGVARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGD
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6019|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_00590|M.leprae_Br4923 GEYLVAGPIDPQVLATVTAWCAQINVLTTNMRVEQHSLEDVFLDLTGRKL
MMAR_0922|M.marinum_M ---------------------------------------------
MUL_0674|M.ulcerans_Agy99 ---------------------------------------------
Mb2419c|M.bovis_AF2122/97 AEALALREGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST
Rv2397c|M.tuberculosis_H37Rv AEALALREGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST
MAV_1785|M.avium_104 AEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA
MAB_4237c|M.abscessus_ATCC_199 ---------------------------------------------
TH_1784|M.thermoresistible__bu ---------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 ---------------------------------------------
MSMEG_6019|M.smegmatis_MC2_155 ---------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK ---------------------------------------------
MLBr_00590|M.leprae_Br4923 R--------------------------------------------