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TPEPILELQRVNKSFGVVHVLHDVDFRVYPGQVTALVGDNGAGKSTLVKAIAGIHPIDSGTYLFEGKPVT VRTPNDVSALGIEVVYQDLALCDNLDIVENMFLGREIKVRGMLDEARMETMARDALKSLSVRTVNSVRQP VSSLSGGQRQTVAIAKSVLWNSKVVLLDEPTAALGVAQTRQVIDLVRRLAGQGLGVVLISHNMNDVFDVA DRICALYLGRVAADVPAADVTHGQVVELITAGRSGNLGLAPAEAAESM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6019 | - | - | 100% (259) | ABC-type sugar transport system ATPase component |
| M. smegmatis MC2 155 | MSMEG_1372 | - | 2e-58 | 48.59% (249) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6802 | - | 1e-50 | 45.49% (244) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-25 | 32.82% (262) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_2607 | - | 3e-43 | 38.43% (242) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-25 | 32.82% (262) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-20 | 28.86% (246) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_3050 | - | 5e-29 | 35.27% (224) | putative glutamate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0922 | - | 2e-25 | 33.77% (228) | ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_1785 | - | 8e-24 | 34.76% (210) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_1784 | - | 1e-28 | 34.65% (228) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_0674 | - | 2e-25 | 33.77% (228) | ABC transporter, ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_5292 | - | 1e-127 | 89.53% (258) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3050|M.abscessus_ATCC_1997 MPVSTDTSTSGESSSAPSVPMIALEHVNKHFG----DLHVLKDITLEIPR
TH_1784|M.thermoresistible__bu -MDSAGADVAVADPAAEAVPMISMRGVNKYFG----SLHVLRDINLDVAR
MMAR_0922|M.marinum_M -MTRAQAPTSPRGG-------VSLHGVDKTFGTAAASVHALRGIDLDIEP
MUL_0674|M.ulcerans_Agy99 -MTRAQAPTSPRGG-------VSLHGVDKTFGTAAASVHALRRIDLDIEP
Mb2419c|M.bovis_AF2122/97 ---------MT--------YAIVVADATKRYG----DFVALDHVDFVVPT
Rv2397c|M.tuberculosis_H37Rv ---------MT--------YAIVVADATKRYG----DFVALDHVDFVVPT
MAV_1785|M.avium_104 ---------MTDAGTDRGDIAITVRDAYKRYG----DFVALDHVDFVVPT
MLBr_01089|M.leprae_Br4923 ------------------MAEIVLEHVNKNYPN---GATAVHDLSITVAD
MSMEG_6019|M.smegmatis_MC2_155 -----------MTPE----PILELQRVNKSFG----VVHVLHDVDFRVYP
Mvan_5292|M.vanbaalenii_PYR-1 ----------MDTQP----PILELRGVNKSFG----VVHVLHDVDFCVYP
Mflv_2607|M.gilvum_PYR-GCK -MTISVEKASSDSKPGGKVPLVELKNIGKSYG----NITALKDISLRVHA
: : * : .: : : :
MAB_3050|M.abscessus_ATCC_1997 GQVVVILGPSGSGKSTLCRTINRLEPIDGGTIRIDGAILP-EEGRALASL
TH_1784|M.thermoresistible__bu GQVVVVLGPSGSGKSTLCRTLNRLEPIDSGAISIDGVALP-AEGRELARL
MMAR_0922|M.marinum_M GELVAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPRALSKF
MUL_0674|M.ulcerans_Agy99 GELVAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPRALSKF
Mb2419c|M.bovis_AF2122/97 GSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQ-----
Rv2397c|M.tuberculosis_H37Rv GSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQ-----
MAV_1785|M.avium_104 GSLTALLGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQ-----
MLBr_01089|M.leprae_Br4923 GEFLILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPK-----
MSMEG_6019|M.smegmatis_MC2_155 GQVTALVGDNGAGKSTLVKAIAGIHPIDSGTYLFEGKPVTVRTPND---V
Mvan_5292|M.vanbaalenii_PYR-1 GQVTALVGDNGAGKSTLVKAIAGIHPIDTGTYLFEGKPVTVHSPND---V
Mflv_2607|M.gilvum_PYR-GCK GEVTGILGDNGAGKSTLIKIIAGLHQQTDGELLVDGEPTRFASPAD---A
*.. ::* .*.**:* . : :. * . *
MAB_3050|M.abscessus_ATCC_1997 R-AEVGMVFQSFNLFSHKTILDNVTLAPIKVRKHNKETARKRAIELLERV
TH_1784|M.thermoresistible__bu R-ADVGMVFQQFNLFAHKTIVDNVALGPMKVRKTPREQARAEAMALLERV
MMAR_0922|M.marinum_M RRDHVGFIFQFFNLIPTLTAKENVEVIVELTGRGD----RRRATELLDAV
MUL_0674|M.ulcerans_Agy99 RRDHVGFIFQFFNLIPTLTAKENVEVIVELTGRGD----RRRATELLDAV
Mb2419c|M.bovis_AF2122/97 -RRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPK-AEIKAKVDNLLQVV
Rv2397c|M.tuberculosis_H37Rv -RRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPK-AEIKAKVDNLLQVV
MAV_1785|M.avium_104 -RRGIGFVFQHYAAFKHLTVRDNVAYGLKVRKRPK-AEIKAKVDNLLEVV
MLBr_01089|M.leprae_Br4923 -DRDIAMVFQSYALYPHMTVRQNIAFPLMLAKVKK-AEIAQKVSETAQIL
MSMEG_6019|M.smegmatis_MC2_155 SALGIEVVYQDLALCDNLDIVENMFLGREIKVRGMLDEARMETMARDALK
Mvan_5292|M.vanbaalenii_PYR-1 SALGVEVVYQDLALCDNLDIVENMFLGRELKRRGMLDEARMETMAREALT
Mflv_2607|M.gilvum_PYR-GCK LGKGIATVYQNLAVVPLMPVWRNFFLGQELRKKRFPFSLDANAMRATTLT
: ::* *. ..
MAB_3050|M.abscessus_ATCC_1997 GIASQ------KDKYPAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALD
TH_1784|M.thermoresistible__bu GVADQ------ADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALD
MMAR_0922|M.marinum_M GLADR------AGSFPGQLSGGQQQRVAIARALITDPDLLLADEPMGALD
MUL_0674|M.ulcerans_Agy99 ELADR------AGSFPGQLSGGQQQRVAIARALITNPDLLLADEPMGALD
Mb2419c|M.bovis_AF2122/97 GLSGF------QSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALD
Rv2397c|M.tuberculosis_H37Rv GLSGF------QSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALD
MAV_1785|M.avium_104 GLSGF------QGRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALD
MLBr_01089|M.leprae_Br4923 DLTDL------LDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLD
MSMEG_6019|M.smegmatis_MC2_155 SLSVR--TVNSVRQPVSSLSGGQRQTVAIAKSVLWNSKVVLLDEPTAALG
Mvan_5292|M.vanbaalenii_PYR-1 SLSVR--TVKSVRQPVSSLSGGQRQTVAIAKSVLWNSKVVLLDEPTAALG
Mflv_2607|M.gilvum_PYR-GCK ELAKMGIDLPDVDVPIGSLSGGQKQCVAIARAVFFGARVLILDEPTAALG
:: .*****:* :*:.::: . .: *** . *.
MAB_3050|M.abscessus_ATCC_1997 PEMVNEVLDVMVSLA-KEGMTMLVVTHEMGFARKAADRIIFMADGAIVED
TH_1784|M.thermoresistible__bu PEMINEVLAVMSALA-ADGMTMLVVTHEMGFARRASDRVVFMSDGAIVED
MMAR_0922|M.marinum_M VATGRRVLELLQQTN-RSGLGVIMVTHNR-AAADVADRIIQMRDGAIVEQ
MUL_0674|M.ulcerans_Agy99 VATGRRVLELLQQTN-RSGLGVIMVTHNR-AAADVADPIIQMRDGAIVEQ
Mb2419c|M.bovis_AF2122/97 AKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQV
Rv2397c|M.tuberculosis_H37Rv AKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQV
MAV_1785|M.avium_104 AKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQI
MLBr_01089|M.leprae_Br4923 AKLRVRTRGEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQI
MSMEG_6019|M.smegmatis_MC2_155 VAQTRQVIDLVRRLA-GQGLGVVLISHNMNDVFDVADRICALYLGRVAAD
Mvan_5292|M.vanbaalenii_PYR-1 VAQTRQVIELVRGLA-ERGVGVVLISHNMNDVFEVADRICALYLGRVAAE
Mflv_2607|M.gilvum_PYR-GCK VKQSGVVLKYITAAK-EAGFGVVFITHNPHHAHLVGDHFVLLNRGRQKLD
: : ::*: . .* . : *
MAB_3050|M.abscessus_ATCC_1997 SDPESFFTNPKSERAKDFLG------------------------------
TH_1784|M.thermoresistible__bu AEPARFFEDPQTDRARDFLG------------------------------
MMAR_0922|M.marinum_M RRN----SAPAEASSVRW--------------------------------
MUL_0674|M.ulcerans_Agy99 RRN----SAPAEASSVRW--------------------------------
Mb2419c|M.bovis_AF2122/97 GSPTDVYDAPANAFVMSFLG---------------------------AVS
Rv2397c|M.tuberculosis_H37Rv GSPTDVYDAPANAFVMSFLG---------------------------AVS
MAV_1785|M.avium_104 GSPTEVYDAPTNAFVMSFLG---------------------------AVS
MLBr_01089|M.leprae_Br4923 GTPDELYERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQ
MSMEG_6019|M.smegmatis_MC2_155 VPAADVTHGQVVELITAGRS----------------------------GN
Mvan_5292|M.vanbaalenii_PYR-1 VKASEVSHGQVVELITAGRS----------------------------GS
Mflv_2607|M.gilvum_PYR-GCK CSYDDITLEHLTQQMAGGDE----------------------------LE
MAB_3050|M.abscessus_ATCC_1997 KILGH---------------------------------------------
TH_1784|M.thermoresistible__bu KILHH---------------------------------------------
MMAR_0922|M.marinum_M --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 TLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTG---VLRAVVDRVVVLGF
Rv2397c|M.tuberculosis_H37Rv TLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTG---VLRAVVDRVVVLGF
MAV_1785|M.avium_104 TLNGTLVRPHDIRVGRTPEMAVAAEDGTAESTG---VARAIVDRVVKLGF
MLBr_01089|M.leprae_Br4923 AMIGQHPVPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGA
MSMEG_6019|M.smegmatis_MC2_155 LGLAPAEAAESM--------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 LGLAPAQAAESM--------------------------------------
Mflv_2607|M.gilvum_PYR-GCK ALSHELRAAKQ---------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MMAR_0922|M.marinum_M --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 EVRVELTS------AATGGAFTAQITRGDAEALALREGDTVYVRATRVPP
Rv2397c|M.tuberculosis_H37Rv EVRVELTS------AATGGAFTAQITRGDAEALALREGDTVYVRATRVPP
MAV_1785|M.avium_104 EVRVELTS------AATGGPFTAQITRGDAEALALREGDTVYVRATRVPP
MLBr_01089|M.leprae_Br4923 DKYIYFTTTGCDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIEL
MSMEG_6019|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------
TH_1784|M.thermoresistible__bu --------------------------
MMAR_0922|M.marinum_M --------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------
Mb2419c|M.bovis_AF2122/97 IAGG---VSGVDDAGVERVKVTST--
Rv2397c|M.tuberculosis_H37Rv IAGG---VSGVDDAGVERVKVTST--
MAV_1785|M.avium_104 ITAGATTVPAVSRDGADEATLTSA--
MLBr_01089|M.leprae_Br4923 AFGTAKIAVFDADSGVNLTVSAPTDA
MSMEG_6019|M.smegmatis_MC2_155 --------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------