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TRYSAPGTTGSVVTFADRYEHFIGGEFVAPAKGEYFENESPVNGVVFTEAARGTADDIERALDAAEAAAT TWGRTSPSERAAVLLKIADRMEADLEKLAVAESWDNGKPVRETLAADLPLAIDHLRYFAGAIRAQEGGLS QIDDDTVAYHFHEPFGVVGLIIPWNFPLLLAMWKLAPALAAGNTVVLKPAEQTPASIHVLLELIADVVPA GVINVVTGFGLEAGKPLAGSPRIAKVSFTGETSTGRAIMQYASQNLIPVTLELGGKSPNIFFADVADTND DFYDRTLEGFTMFALNQGETCTCPSRALIQADIYDEFLQRAVARVGKIVQGNPLDTATMIGAQASRTQFE KIVQYFEIAKDEGAVVRTGGQAATVDADIAGGYYIEPTIIEGSNSMRVFQEEIFGPVVCATSFDHYADAI KIANDSLYGLAGGVWTRNGTVAYRASRDIQAGRIFVNDYHNYPAHAAFGGYKQSGIGRENHKMMLEHYQQ TKCVLTSYATTAKGFF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1306 | - | - | 100% (507) | aldehyde dehydrogenase (NAD) family protein |
| M. smegmatis MC2 155 | MSMEG_0900 | - | 0.0 | 70.41% (507) | eptc-inducible aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1543 | - | 0.0 | 68.84% (507) | eptc-inducible aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0467 | - | 0.0 | 68.64% (507) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4952 | - | 0.0 | 70.61% (507) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0458 | - | 0.0 | 68.64% (507) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 2e-48 | 30.73% (449) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0972 | - | 0.0 | 69.43% (507) | putative aldehyde dehydrogenase |
| M. marinum M | MMAR_4912 | - | 0.0 | 71.40% (507) | aldehyde dehydrogenase |
| M. avium 104 | MAV_4691 | - | 0.0 | 68.84% (507) | eptc-inducible aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3284 | - | 0.0 | 71.66% (494) | PUTATIVE eptc-inducible aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_0494 | - | 0.0 | 70.81% (507) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1468 | - | 0.0 | 71.40% (507) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4912|M.marinum_M MTVFARPGAHSSLMTFESRYGNFIGGEWVAPAAGEYFEDLTPVTGAPFCE
MUL_0494|M.ulcerans_Agy99 MTVFARPGVHSSLMTFESRYDNFIGGEWVAPAAGEYFEDLTPVTGAPFCE
Mb0467|M.bovis_AF2122/97 MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCE
Rv0458|M.tuberculosis_H37Rv MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCE
MAV_4691|M.avium_104 MTVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPVTGQTFCE
TH_3284|M.thermoresistible__bu -------------MSFESRYDNFIGGEWVAPVGGEYFENPSPVTGQPFCE
Mflv_4952|M.gilvum_PYR-GCK MTVYARPGADGSLMSFKPRYDNFIGGQWVAPTAGRYFENPSPVTGQPFTE
Mvan_1468|M.vanbaalenii_PYR-1 MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPVTGQPFTE
MAB_0972|M.abscessus_ATCC_1997 MAKYAAPGTEGSAVTFAPRYDNFIGGEWVAPADGQYFENASPIDGKVFTR
MSMEG_1306|M.smegmatis_MC2_155 MTRYSAPGTTGSVVTFADRYEHFIGGEFVAPAKGEYFENESPVNGVVFTE
MLBr_02573|M.leprae_Br4923 ----------------------------------MSIATINPATGETVKT
: .* * .
MMAR_4912|M.marinum_M VPRSTDVDVEKALDAAHAAAPAWGKAAPAERAAILHKIADRMEANLEALA
MUL_0494|M.ulcerans_Agy99 VPRSTDVDVEKALDAAHAAAPAWGKAAPAERATILHKIADRMEANLEALA
Mb0467|M.bovis_AF2122/97 VPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALA
Rv0458|M.tuberculosis_H37Rv VPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALA
MAV_4691|M.avium_104 VARSDEADVDKALDAAHAAAPAWGKTAPPERAAILNKIADRIEENLESLA
TH_3284|M.thermoresistible__bu VARSTEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRIEANLESIA
Mflv_4952|M.gilvum_PYR-GCK VARSDEADIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIEENLESIA
Mvan_1468|M.vanbaalenii_PYR-1 VARSDESDIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIEENLESIA
MAB_0972|M.abscessus_ATCC_1997 VARGTAPDIEKALDAAHAAAEAWGNTSAAERSNALLRIADRMEQHIERLA
MSMEG_1306|M.smegmatis_MC2_155 AARGTADDIERALDAAEAAATTWGRTSPSERAAVLLKIADRMEADLEKLA
MLBr_02573|M.leprae_Br4923 FTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLLEAEANQSA
. ::: *: * * : .:: .:*: ** :: . *
MMAR_4912|M.marinum_M LAESWDNGKPIRETLNADIPLAIDHFRYFAG---AIRAQEGSLSQIDSDT
MUL_0494|M.ulcerans_Agy99 LAESWDNGKPIREALNADIPLAIDHFRYFAG---AIRAQEGSLSQIDSDT
Mb0467|M.bovis_AF2122/97 VAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGALSQIDEDT
Rv0458|M.tuberculosis_H37Rv VAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGALSQIDEDT
MAV_4691|M.avium_104 VAEVWDNGKPIREALAADIPLAADHFRYFAG---ALRAQEGSLSQIDDDT
TH_3284|M.thermoresistible__bu LAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSLSQIDDDT
Mflv_4952|M.gilvum_PYR-GCK LAESWDNGKPIRETLNADLPLAVDHFRYFAG---CIRAQEGSLSEVDADT
Mvan_1468|M.vanbaalenii_PYR-1 LAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSLSEIDDDT
MAB_0972|M.abscessus_ATCC_1997 VAETWDNGKPIRESLNADIPLAIDHFRYFAG---VLRAQEGSISEIDHDT
MSMEG_1306|M.smegmatis_MC2_155 VAESWDNGKPVRETLAADLPLAIDHLRYFAG---AIRAQEGGLSQIDDDT
MLBr_02573|M.leprae_Br4923 ALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEAAAVGAS
: **.::.: : * . :**:* : *:* . : :
MMAR_4912|M.marinum_M VAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPAS
MUL_0494|M.ulcerans_Agy99 VAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPAS
Mb0467|M.bovis_AF2122/97 VAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPAS
Rv0458|M.tuberculosis_H37Rv VAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPAS
MAV_4691|M.avium_104 VAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPVS
TH_3284|M.thermoresistible__bu VAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPAS
Mflv_4952|M.gilvum_PYR-GCK VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPAS
Mvan_1468|M.vanbaalenii_PYR-1 VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPAS
MAB_0972|M.abscessus_ATCC_1997 VAYHFHEPLGVVGQIIPWNFPLLMAVWKLAPALAAGNCVVLKPAEQTPAS
MSMEG_1306|M.smegmatis_MC2_155 VAYHFHEPFGVVGLIIPWNFPLLLAMWKLAPALAAGNTVVLKPAEQTPAS
MLBr_02573|M.leprae_Br4923 KALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQC
* ::*:*** ::*****: **** *** :** *.:.* .
MMAR_4912|M.marinum_M ILYLMSLIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MUL_0494|M.ulcerans_Agy99 ILYLMSLIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
Mb0467|M.bovis_AF2122/97 VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGR
Rv0458|M.tuberculosis_H37Rv VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGR
MAV_4691|M.avium_104 VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKIAFTGETTTGR
TH_3284|M.thermoresistible__bu VMYLMSLIGDLLPPGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
Mflv_4952|M.gilvum_PYR-GCK ILYLMEVIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
Mvan_1468|M.vanbaalenii_PYR-1 ILYLMELIADLLPAGVINVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MAB_0972|M.abscessus_ATCC_1997 ILVLMELIADLLPSGTVNVVNGFGVEAGKPLASSPRIAKIAFTGETTTGR
MSMEG_1306|M.smegmatis_MC2_155 IHVLLELIADVVPAGVINVVTGFGLEAGKPLAGSPRIAKVSFTGETSTGR
MLBr_02573|M.leprae_Br4923 ALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLTGSEPAGQ
* .:*. . . :. :. :.: . *:* ::**. .:*:
MMAR_4912|M.marinum_M LIMQYASQNLIPVTLELGGKSPNIFFSDVLAAHDDYQDKALEGFTMFALN
MUL_0494|M.ulcerans_Agy99 LIMQYASQNLIPVTLELGGKSPNIFFPDVLAAHDDYQDKALEGFTMFALN
Mb0467|M.bovis_AF2122/97 LIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALN
Rv0458|M.tuberculosis_H37Rv LIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALN
MAV_4691|M.avium_104 LIMQYASQNLIPVTLELGGKSPNIFFSDVMAKADDYQDKALEGFTMFALN
TH_3284|M.thermoresistible__bu LIMQYASQNLIPVTLELGGKSPNIFFADVMAASDDFCDKALEGFTMFALN
Mflv_4952|M.gilvum_PYR-GCK LIMQYASQNLIPVTLELGGKSPNIFFNDVLAASDDYQDKALEGFTMFALN
Mvan_1468|M.vanbaalenii_PYR-1 LIMQYASQNLIPVTLELGGKSPNIFFNDVLAQADNYQDKALEGFTMFALN
MAB_0972|M.abscessus_ATCC_1997 LIMQYATENIIPVTLELGGKSPNIFMPDVMAADDAFLDKALEGFTMFALN
MSMEG_1306|M.smegmatis_MC2_155 AIMQYASQNLIPVTLELGGKSPNIFFADVADTNDDFYDRTLEGFTMFALN
MLBr_02573|M.leprae_Br4923 AVGAIAGNEIKPTVLELGGSDPFIVMP-----SADLDAAVATAVTGRVQN
: * .:: *..*****..* *.: . ..* . *
MMAR_4912|M.marinum_M QGEVCTCPSRGLIQADIYDRFLELAAIRTKAVRQGDPLDTETMIGAQASN
MUL_0494|M.ulcerans_Agy99 QGEVCTCPSRGLIQADIYDRFLELAAIRTKAVRQGDPLDTETMIGAQASN
Mb0467|M.bovis_AF2122/97 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASN
Rv0458|M.tuberculosis_H37Rv QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASN
MAV_4691|M.avium_104 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDSETMLGSQASN
TH_3284|M.thermoresistible__bu QGEVCTCPSRSLIQADIYDEFLELATIRTKAVRQGDPLDTETMVGAQASN
Mflv_4952|M.gilvum_PYR-GCK QGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASN
Mvan_1468|M.vanbaalenii_PYR-1 QGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASN
MAB_0972|M.abscessus_ATCC_1997 QGEVCTCPSRALVHASIYDEFIARAITRVEAIVGGDPLDEDTMIGAQASN
MSMEG_1306|M.smegmatis_MC2_155 QGETCTCPSRALIQADIYDEFLQRAVARVGKIVQGNPLDTATMIGAQASR
MLBr_02573|M.leprae_Br4923 NGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATE
:*: * ...* : :*.***.*: * : *:* * * :*. *:.
MMAR_4912|M.marinum_M DQLQKILSYIEIGKEEGARVVTGGERCELGGDLNGGYYVQPTIFEGTNNM
MUL_0494|M.ulcerans_Agy99 DQLQKILSYIEIGKEEGARVVTGGERCELGGDLNGGYYVQPTIFEGTNNM
Mb0467|M.bovis_AF2122/97 DQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNM
Rv0458|M.tuberculosis_H37Rv DQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNM
MAV_4691|M.avium_104 DQLEKVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTIFAGNNKM
TH_3284|M.thermoresistible__bu DQLEKILSYIDIGRSEGATVVTGGERAELGGDLSGGYYVQPTIFTGDNSM
Mflv_4952|M.gilvum_PYR-GCK DQLEKILSYIEIGKSEGAKVVTGGERAELGGDLNGGYYVAPTIFTGNNTM
Mvan_1468|M.vanbaalenii_PYR-1 DQLEKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTIFTGHNKM
MAB_0972|M.abscessus_ATCC_1997 DQYEKILSYIDIGRQEGAQVLTGGDARKVS-EYPDGAYIQPTVFAGTNNM
MSMEG_1306|M.smegmatis_MC2_155 TQFEKIVQYFEIAKDEGAVVRTGGQAATVDADIAGGYYIEPTIIEGSNSM
MLBr_02573|M.leprae_Br4923 SGRAQVEQQVDAAAAAGAVIRCGGK----RPDRPGWFYPPTVITDITKDM
:: . . . ** : **. : . * ..: : *
MMAR_4912|M.marinum_M RIFQEEIFGPVVSVTSFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
MUL_0494|M.ulcerans_Agy99 RIFQEEIFGPVVSVTLFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
Mb0467|M.bovis_AF2122/97 RIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAG
Rv0458|M.tuberculosis_H37Rv RIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAG
MAV_4691|M.avium_104 RIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
TH_3284|M.thermoresistible__bu RIFQEEIFGPVVAVTSFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
Mflv_4952|M.gilvum_PYR-GCK RIFQEEIFGPVVAVTSFTDYDDAISLANDTLYGLGAGVWSRNGNTAYRAG
Mvan_1468|M.vanbaalenii_PYR-1 RIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
MAB_0972|M.abscessus_ATCC_1997 RIFQEEIFGPVLSVAKFDSLDEALKIANDTLYGLGAGVWSRDMTNAYRLG
MSMEG_1306|M.smegmatis_MC2_155 RVFQEEIFGPVVCATSFDHYADAIKIANDSLYGLAGGVWTRNGTVAYRAS
MLBr_02573|M.leprae_Br4923 ALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFI
:: :*:**** .. :*: :** : :**....*::: . :
MMAR_4912|M.marinum_M RDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
MUL_0494|M.ulcerans_Agy99 RDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
Mb0467|M.bovis_AF2122/97 RDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLV
Rv0458|M.tuberculosis_H37Rv RDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLV
MAV_4691|M.avium_104 RDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNMLV
TH_3284|M.thermoresistible__bu RDIKAGRVWTNCYHVYPAHAAFGGYKQSGIGRENHTMMLDHYQQTKNLLV
Mflv_4952|M.gilvum_PYR-GCK RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHRMMLDHYQQTKNLLV
Mvan_1468|M.vanbaalenii_PYR-1 RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
MAB_0972|M.abscessus_ATCC_1997 RGIKAGRVWTNCYHQYPAHAAFGGYKKSGIGRENHKMMLDHYQQTKNILV
MSMEG_1306|M.smegmatis_MC2_155 RDIQAGRIFVNDYHNYPAHAAFGGYKQSGIGRENHKMMLEHYQQTKCVLT
MLBr_02573|M.leprae_Br4923 DNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWI
.* **::: * .. .*** *:** *** : .: : * :
MMAR_4912|M.marinum_M SYGSKAQGFF
MUL_0494|M.ulcerans_Agy99 SYGSKAQGFF
Mb0467|M.bovis_AF2122/97 SYSDKALGFF
Rv0458|M.tuberculosis_H37Rv SYSDKALGFF
MAV_4691|M.avium_104 SYSNKAQGFF
TH_3284|M.thermoresistible__bu SYSTKAQGFF
Mflv_4952|M.gilvum_PYR-GCK SYSDQALGFF
Mvan_1468|M.vanbaalenii_PYR-1 SYSDKALGFF
MAB_0972|M.abscessus_ATCC_1997 SYSPDAAGFF
MSMEG_1306|M.smegmatis_MC2_155 SYATTAKGFF
MLBr_02573|M.leprae_Br4923 A---------
: